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Study examines events that lead to sepsis by Streptococcus pneumoniae

Study examines events that lead to sepsis by Streptococcus pneumoniae

An international team of academics, including Professor Marco Oggioni from the University of Leicester's Department of Genetics, has studied how localised infections can turn into the dangerous systematic disease sepsis - and has identified for the first time through genetic evidence that a single bacteria could be the cause. [More]
Researchers find immune receptor for uric acid crystals

Researchers find immune receptor for uric acid crystals

The surface of immune system cells is home to a number of receptors which are able to detect pathogens. As soon as these receptors are activated, inflammation occurs and the body's defense mechanisms kick in. Immune cells also have receptors that regulate or even suppress immunological responses to prevent damage to individual cells. [More]
Scientist receives $147,157 grant from NIH to find cure for infectious disease

Scientist receives $147,157 grant from NIH to find cure for infectious disease

A Clemson University scientist was awarded a two-year, $147,157 grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to find a cure for an infectious disease. [More]
Many community hospitals prescribe ineffective antibiotics for patients with bloodstream infections

Many community hospitals prescribe ineffective antibiotics for patients with bloodstream infections

Growing drug resistance, a high prevalence of S. aureus bacteria and ineffective antibiotics prescribed to one in three patients are among the challenges facing community hospitals in treating patients with serious bloodstream infections, according to researchers at Duke Medicine. [More]
New research raises hopes of new class of drugs to combat antibiotic resistant infections

New research raises hopes of new class of drugs to combat antibiotic resistant infections

New research has found some compounds effective in blocking the proliferation of certain bacteria, raising hopes of a new class of drugs to combat antibiotic resistant infections [More]
Gut bacteria and blood cell development relationship helps immune system fight infection

Gut bacteria and blood cell development relationship helps immune system fight infection

The human relationship with microbial life is complicated. At almost any supermarket, you can pick up both antibacterial soap and probiotic yogurt during the same shopping trip. [More]
Parasites in human are most likely to interact via food source

Parasites in human are most likely to interact via food source

Over 1,400 species of parasites - viruses, bacteria, fungi, intestinal worms and protozoa - are able to infect humans. In most cases, the right medicine against a parasite cures the patient. [More]
UNIGE discovers new class of molecules toxic for Plasmodium pathogen

UNIGE discovers new class of molecules toxic for Plasmodium pathogen

​The malaria parasite is particularly pernicious since it is built to develop resistance to treatments. The lack of new therapeutic approaches also contributes to the persistence of this global scourge. [More]
Sleep apnoea may be risk factor for pneumonia

Sleep apnoea may be risk factor for pneumonia

People who suffer from sleep apnoea face an increased risk of developing pneumonia, a large epidemiological study indicates. [More]
Researchers examine association between diabetes and obesity

Researchers examine association between diabetes and obesity

It's by now well established that obesity is a major risk factor for diabetes. But what exactly is it about extra body fat that leads to insulin resistance and blood glucose elevation, the hallmarks of diabetes? [More]

Six papers published by PNAS in 2013 to receive Cozzarelli Prize

The Proceedings of the National Academy of Sciences (PNAS) Editorial Board has selected six papers published by PNAS in 2013 to receive the Cozzarelli Prize, an award that recognizes outstanding contributions to the scientific disciplines represented by the National Academy of Sciences. [More]
New drug is effective against superbug MRSA

New drug is effective against superbug MRSA

"I routinely call hospitals and request their yearly antibiotic susceptibility testing data," said Washington University in St. Louis' Timothy Wencewicz. "The log might say, for example, that they've treated hundreds of patients for Acinetobacter baumanni, a bacterium brought into U.S. hospitals by soldiers wounded in the Iraq war, with 30 different antibiotics. [More]
Small-molecule drug effective in protecting nonhuman primates from lethal Marburg virus

Small-molecule drug effective in protecting nonhuman primates from lethal Marburg virus

For the first time, scientists have demonstrated the effectiveness of a small-molecule drug in protecting nonhuman primates from the lethal Marburg virus. Their work, published online in the journal Nature, is the result of a continuing collaboration between Army scientists and industry partners that also shows promise for treating a broad range of other viral diseases. [More]
New methodology for rapid detection of antibiotics in blood paves way to drug development, personalized treatment

New methodology for rapid detection of antibiotics in blood paves way to drug development, personalized treatment

A new methodology for rapidly measuring the level of antibiotic drug molecules in human blood serum has been developed, paving the way to applications within drug development and personalised medicine. [More]
Scientists reveal two regulatory mechanisms that keep the body's immune response in check

Scientists reveal two regulatory mechanisms that keep the body's immune response in check

A Keck Medicine of USC-led team of microbiologists has identified previously unknown interactions between critical proteins in the human immune response system, uncovering two independent regulatory mechanisms that keep the body's immune response in check. Their findings appear in the February 2014 edition of Cell Host & Microbe, the top peer-reviewed scientific journal that focuses on the study of cell-pathogen interaction. [More]
Cognitive decline in obese diabetic mice can be reversed with regular exercise, surgical removal of belly fat

Cognitive decline in obese diabetic mice can be reversed with regular exercise, surgical removal of belly fat

Cognitive decline that often accompanies obesity and diabetes can be reversed with regular exercise or surgical removal of belly fat, scientists report. [More]

Researchers produce extremely accurate and detailed images of "toxic injections"

Bacteria have developed many different ways of smuggling their toxic cargo into cells. Tripartite Tc toxin complexes, which are used by bacteria like the plague pathogen Yersinia pestis and the insect pathogen Photorhabdus luminescens, are particularly unusual. [More]

iCOMOS conference to explore science behind ‘One Health’ in complex environments

The University of Minnesota will present an international conference on the science behind One Health this spring in Minneapolis. [More]
Researchers discover 'microbial Pompeii' preserved on teeth of skeletons around 1,000 years old

Researchers discover 'microbial Pompeii' preserved on teeth of skeletons around 1,000 years old

An international team of researchers have discovered a 'microbial Pompeii' preserved on the teeth of skeletons around 1,000 years old. The key to the discovery is the dental calculus (plaque) which preserves bacteria and microscopic particles of food on the surfaces of teeth, effectively creating a mineral tomb for microbiomes. [More]
Researchers discover that immune cells control blood stem cells in bone marrow

Researchers discover that immune cells control blood stem cells in bone marrow

Researchers in Bern have discovered that, during a viral infection, immune cells control the blood stem cells in the bone marrow and therefore also the body's own defences. The findings could allow for new forms of therapy, such as for bone marrow diseases like leukaemia. [More]