Pathology News and Research RSS Feed - Pathology News and Research

Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology.

Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.
Heat-shock protein 90 enables ER+ breast cancers to develop resistance to hormonal therapy

Heat-shock protein 90 enables ER+ breast cancers to develop resistance to hormonal therapy

Long known for its ability to help organisms successfully adapt to environmentally stressful conditions, the highly conserved molecular chaperone heat-shock protein 90 (HSP90) also enables estrogen receptor-positive (ER+) breast cancers to develop resistance to hormonal therapy. [More]
Alere Determine HIV-1/2 Ag/Ab Combo test receives CLIA Waiver from FDA

Alere Determine HIV-1/2 Ag/Ab Combo test receives CLIA Waiver from FDA

Alere Inc., a global leader in rapid diagnostic tests, today announced that the U.S. Food and Drug Administration (FDA) has granted CLIA (Clinical Laboratory Improvement Amendments) Waiver for the Alere Determine™ HIV-1/2 Ag/Ab Combo test. [More]
CTI BioPharma presents data from Phase 3 trial of pacritinib in AML patients at ASH 2014

CTI BioPharma presents data from Phase 3 trial of pacritinib in AML patients at ASH 2014

CTI BioPharma Corp. today announced data showing treatment with pacritinib, an investigational oral multikinase inhibitor in Phase 3 clinical development, preferentially killed acute myeloid leukemia (AML) cells with FLT3 mutations, overcame stromal protection and suppressed leukemic outgrowth from stroma adherent AML cells in both medium-term (7-14 days) and long-term (5-6 weeks) assays. [More]
McMaster University researchers identify hormone that contributes to obesity, diabetes

McMaster University researchers identify hormone that contributes to obesity, diabetes

Researchers from McMaster University have identified an important hormone that is elevated in obese people and contributes to obesity and diabetes by inhibiting brown fat activity. [More]
SI-BONE wins Gold 2014 International MarCom Award for SI Joint Patient Community website

SI-BONE wins Gold 2014 International MarCom Award for SI Joint Patient Community website

SI-BONE, Inc., a medical device company that pioneered the use of the iFuse Implant System, a minimally invasive surgical (MIS) device indicated for fusion for certain disorders of the sacroiliac (SI) joint, won the Gold 2014 International MarCom Award for its SI Joint Patient Community website and an Honorable Mention for the SI Buddy Patient Networking Program. [More]
AbbVie reports results from venetoclax Phase 2 clinical trial in AML at ASH 2014

AbbVie reports results from venetoclax Phase 2 clinical trial in AML at ASH 2014

AbbVie presented during an oral presentation at the American Society of Hematology's 56th Annual Meeting new results from a Phase 2 study of investigational compound venetoclax (ABT-199/GDC-0199) in patients with acute myelogenous leukemia (AML). AML is an aggressive and deadly type of blood cancer, in which the body produces too many of a specific type of white blood cell (myeloblast), which can crowd out healthy blood cells. [More]
Researchers identify new targets for future CLL therapies

Researchers identify new targets for future CLL therapies

Chronic lymphocytic leukemia (CLL) is among the most frequent leukemias affecting adults in Western countries. It usually occurs in older patients, does not cause any symptoms for a long time and is often only discovered by accident. Despite treatment, relapses frequently occur. The immunologists Dr. Kristina Heinig and Dr. Uta Höpken (Max Delbrück Center for Molecular Medicine, MDC, Berlin-Buch) and the hematologist Dr. Armin Rehm (MDC and Charité - Universitätsmedizin Berlin) have now discovered why this is so. [More]
Malnutrition predicts long-term survival in elderly patients undergoing Whipple procedure

Malnutrition predicts long-term survival in elderly patients undergoing Whipple procedure

Malnutrition is an important factor predicting long-term survival in older patients undergoing pancreaticoduodenectomy (PD) (commonly called the Whipple procedure) to treat benign tumors and cysts of the pancreas as well as pancreatitis, according to new study results published in the December issue of the Journal of the American College of Surgeons. [More]
Leica Biosystems completes acquisition of Devicor Medical Products

Leica Biosystems completes acquisition of Devicor Medical Products

Leica Biosystems, a global leader in anatomic pathology laboratory solutions and instruments, announced today that it has successfully completed its previously announced acquisition of Devicor Medical Products, Inc. [More]
Five speech pathology students from Griffith to take on jobs with Queensland Health

Five speech pathology students from Griffith to take on jobs with Queensland Health

Griffith’s Master of Speech Pathology department is delighted following the amazing success of five of its graduating students who are set to take on jobs with Queensland Health. [More]
Aging in Rural Places: A new book examines health and wellness in rural areas

Aging in Rural Places: A new book examines health and wellness in rural areas

Kristina Hash, associate professor in the School of Social Work at West Virginia University, has co-edited and co-authored a book examining rural areas and discussing the issues, programs and policies designed to meet residents' needs. [More]
Experts report three key topics that may make difference in the battle against Alzheimer's disease

Experts report three key topics that may make difference in the battle against Alzheimer's disease

Detection, prevention, and preclinical treatment are three key areas that may make a difference in the battle to reduce the rapid rise of new Alzheimer's disease (AD) cases every year. These three topics are the focus of an important new supplement to the Journal of Alzheimer's Disease. [More]
Neuroimaging markers have synergistic effect on cognitive decline

Neuroimaging markers have synergistic effect on cognitive decline

The Alzheimer disease neuroimaging markers β-amyloid and neurodegeneration have synergistic effects on the rate of cognitive decline in clinically normal people, research shows. [More]
Real-time surgical guidance study to evaluate TriVersa NanoMate with LESA capability from Advion

Real-time surgical guidance study to evaluate TriVersa NanoMate with LESA capability from Advion

Advion, Inc. announces that is its TriVersa NanoMate with liquid extraction surface analysis (LESA) capability will be evaluated as part of a study at Brigham and Women’s Hospital. [More]
Researchers identify possible prognostic biomarker in triple-negative breast cancer

Researchers identify possible prognostic biomarker in triple-negative breast cancer

"Triple-negative" breast cancer (TNBC) occurs in patients whose cells do not express receptors for estrogen, progesterone, and/or human epidermal growth factor receptor 2 (ER-/PR-/HER2-). [More]
Researchers explore how to turn on the activity of paternal gene

Researchers explore how to turn on the activity of paternal gene

Most genes are inherited as two working copies, one from the mother and one from the father. However, in a few instances, a gene is imprinted, which means that one copy is silenced. This is called genomic imprinting. If the active copy is mutated, then disease results, even though the silenced gene copy may be normal. [More]
Mayo Clinic recommends genetic screening for patients with triple-negative breast cancer

Mayo Clinic recommends genetic screening for patients with triple-negative breast cancer

Most patients with triple-negative breast cancer should undergo genetic testing for mutations in known breast cancer predisposition genes, including BRCA1 and BRCA2, a Mayo Clinic-led study has found. [More]
Fenofibrate benefits in diabetic retinopathy mediated through PPARα

Fenofibrate benefits in diabetic retinopathy mediated through PPARα

Peroxisome proliferator–activated receptor α exerts protective effects on retinal pericytes, shows research that explains why fenofibrate is protective against diabetic retinopathy. [More]
Study provides proof of concept for developing antibodies against human pathogens

Study provides proof of concept for developing antibodies against human pathogens

Scientists investigating the potentially deadly hantavirus have used a novel approach to developing protective antibodies against it. Their work, published in today's online edition of Science Translational Medicine, provides proof of concept for producing antibodies against a broad range of human pathogens. [More]
Salford researchers to support adoption of CAD technologies in footwear manufacturing

Salford researchers to support adoption of CAD technologies in footwear manufacturing

A University of Salford team headed by Dr Anita Williams, Senior Lecturer at the School of Health Sciences, is moving into its second year of delivering sector-leading education content for industries in the UK and European Union, as part of an EU Leonardo da-Vinci funded project - INGA3D. [More]