Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

CSHL scientists solve the mystery of why some infants born with grave syndrome

By identifying a protein that acts as a genetic modifier, scientists at Cold Spring Harbor Laboratory have solved the mystery of why some infants are born with a grave syndrome consisting of cleft palate and major deformities of the skin and limbs, while other infants bearing the same predisposing genetic mutation bear little or no sign of the illness, called EEC.

14 Jun 2013

SV Bio receives CLIA certification for in silico diagnostics laboratory

Silicon Valley Biosystems today announced that it has received Clinical Laboratory Improvement Amendment certification from the California Department of Public Health for its in silico diagnostics laboratory.

13 Jun 2013

Study unravels cause of hearing loss in humans

A novel genetic mutation was first identified in 2010 as causing hearing loss in humans. Researchers have now discovered that this mutation induces malfunction of an inhibitor of an enzyme commonly found in our body that destroys proteins.

13 Jun 2013

Hypometabolism in brain regions of cognitively normal patients associated with Alzheimer's disease

Alzheimer's disease has been linked in many studies to amyloid plaque buildup in the brain, but new research is finding a common thread between amyloid burden and lower energy levels, or metabolism, of neurons in certain areas of the brain associated with Alzheimer's disease-even for people with no sign of cognitive decline.

12 Jun 2013

PET and MR imaging can improve quality of life and survival for advanced breast cancer patients

For patients with advanced breast cancer, positron emission tomography and magnetic resonance imaging can improve quality of life and survival by providing physicians with information on the effectiveness of chemotherapy prior to surgery, say researchers presenting at the 2013 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging.

12 Jun 2013

Research could lead to new ways to combat chlamydia

A protein secreted by the chlamydia bug has a very unusual structure, according to scientists in the School of Medicine at The University of Texas Health Science Center San Antonio. The discovery of the protein's shape could lead to novel strategies for diagnosing and treating chlamydia, a sexually transmitted disease that infects an estimated 2.8 million people in the U.S. each year.

12 Jun 2013

Cytosine methylation plays key role in development of childhood ALL

Changes in an epigenetic mechanism that turns expression of genes on and off may be as important as genetic alterations in causing pediatric acute lymphoblastic leukemia, according to a study led by scientists at St. Jude Children's Research Hospital and published in the June 10 online edition of the Journal of Clinical Investigation.

11 Jun 2013

Powerful new mass spectrometry systems and solutions for life-science research, clinical research, pharma and applied markets announced by Bruker

At the 61st ASMS Conference on Mass Spectrometry and Allied Topics, Bruker today announced mass spectrometry-based product introductions for life-science and clinical research, for biotech/pharma/CRO customers, as well as for industrial and applied markets. The new mass spectrometry systems and solutions are designed to deliver confident analyses with dramatically enhanced resolution, sensitivity and precision.

10 Jun 2013

Bone tumor identified in the rib of 120,000-year-old Neandertal

The first-known definitive case of a benign bone tumor has been discovered in the rib of a young Neandertal who lived about 120,000 years ago in what is now present-day Croatia.

10 Jun 2013

Scientists find that mice develop age-related progressive motor symptoms of Parkinson's disease

The presence of Lewy bodies in nerve cells, formed by intracellular deposits of the protein α-synuclein, is a characteristic pathologic feature of Parkinson's Disease (PD). In the quest for an animal model of PD that mimics motor and non-motor symptoms of human PD, scientists have developed strains of mice that overexpress α-synuclein.

10 Jun 2013

Novel abnormalities in FGFR gene identified in a spectrum of cancers

Novel abnormalities in the FGFR gene, called FGFR fusions, were identified in a spectrum of cancers, and preliminary results with cancer cells harboring FGFR fusions suggested that some patients with these cancers may benefit from treatment with FGFR inhibitor drugs, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.

10 Jun 2013

Cancer cells' appetite for sugar may have serious consequences for immune cell function

Cancer cells' appetite for sugar may have serious consequences for immune cell function, researchers at Washington University School of Medicine in St. Louis have learned.

7 Jun 2013

Study suggests erectile dysfunction in young men may be more prevalent than previously thought

In a recent analysis of one outpatient clinic, one in four men seeking medical help for newly-developed erectile dysfunction (ED) was younger than 40 years, and nearly half of young men with the condition had severe ED.

7 Jun 2013

Communications aimed at shifting organizational culture can overcome gender differences in career paths

To attract and maintain a diverse, qualified academic workforce, institutions of higher education should have - and promote - policies to help balance career and family life, according to an article published by UC Davis researchers in the June 2013 issue of Academic Medicine.

6 Jun 2013

Winners of EFIC-Grünenthal-Grant announced

For the 8th time the European Federation of IASP Chapters in cooperation with the pharmaceutical company Grünenthal Group announced the EFIC-Grünenthal-Grant (E-G-G) - a grant aimed to support young scientists at an early stage of their experimental projects on clinical and human volunteer-based pain research.

6 Jun 2013

Investigators report possible missing link necessary to prevent osteoporosis

By analyzing biopsy specimens from patients with postmenopausal osteoporosis and primary hyperparathyroidism, investigators have begun to pay increasing attention to "reversal cells," which prepare for bone formation during bone remodeling.

6 Jun 2013

Scientists suggest that Oprl1 receptor is altered in mice with PTSD-like symptoms

When injected into mice immediately following a traumatic event, a new drug prevents the animals from developing memory problems and increased anxiety that are indicative of post-traumatic stress disorder.

6 Jun 2013

Study suggests modulation of "enhancer-directed RNAs" can alter gene expression in living cells

In a pair of distinct but complementary papers, researchers at the University of California, San Diego School of Medicine and colleagues illuminate the functional importance of a relatively new class of RNA molecules.

5 Jun 2013

Blocking MHCII action rescues nerve cells from Parkinson's disease mechanisms, researchers find

The same mechanism that lets the immune system mount a massive attack against invading bacteria contributes to the destruction of brain cells as part of Parkinson's disease, according to a study published online today in the Journal of Neuroscience.

5 Jun 2013

American Academy of Otolaryngology publishes new guideline on “Improving Voice Outcomes after Thyroid Surgery”

The American Academy of Otolaryngology-Head and Neck Surgery Foundation on Tuesday published a new Clinical Practice Guideline on "Improving Voice Outcomes after Thyroid Surgery" to recognize the importance of the patient's voice and the potential impact thyroid surgery can have on it.

4 Jun 2013

Pathology News and Research

Further Reading

CSHL scientists solve the mystery of why some infants born with grave syndrome

SV Bio receives CLIA certification for in silico diagnostics laboratory

Study unravels cause of hearing loss in humans

Hypometabolism in brain regions of cognitively normal patients associated with Alzheimer's disease

PET and MR imaging can improve quality of life and survival for advanced breast cancer patients

Research could lead to new ways to combat chlamydia

Cytosine methylation plays key role in development of childhood ALL

Powerful new mass spectrometry systems and solutions for life-science research, clinical research, pharma and applied markets announced by Bruker

Bone tumor identified in the rib of 120,000-year-old Neandertal

Scientists find that mice develop age-related progressive motor symptoms of Parkinson's disease

Novel abnormalities in FGFR gene identified in a spectrum of cancers

Cancer cells' appetite for sugar may have serious consequences for immune cell function

Study suggests erectile dysfunction in young men may be more prevalent than previously thought

Communications aimed at shifting organizational culture can overcome gender differences in career paths

Winners of EFIC-Grünenthal-Grant announced

Investigators report possible missing link necessary to prevent osteoporosis

Scientists suggest that Oprl1 receptor is altered in mice with PTSD-like symptoms

Study suggests modulation of "enhancer-directed RNAs" can alter gene expression in living cells

Blocking MHCII action rescues nerve cells from Parkinson's disease mechanisms, researchers find

American Academy of Otolaryngology publishes new guideline on “Improving Voice Outcomes after Thyroid Surgery”

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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