Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Deciphering the role of GPCRs in obesity pathology for drug development

Announcing a new publication for Acta Materia Medica journal. G protein-coupled receptors (GPCRs) are important, potential drug targets for the treatment of metabolic disorders, such as obesity.

5 Mar 2024

Scientists take the first step toward early diagnosis of metastasis formation

Metastases are largely responsible for the death rate of patients with solid cancers; the prognosis of cancer patients reduces significantly if metastases are diagnosed.

4 Mar 2024

Researchers discover a noninvasive, low-cost test to detect oral cancer

Oral cancers and precancerous mouth lesions are considered especially difficult to diagnose early and accurately.

4 Mar 2024

PharmaKure partners with Sheffield Hallam University to develop epigenetic markers for Alzheimer’s disease prediction

PharmaKure, a clinical stage pharmaceutical company developing precision medicines for Alzheimer’s Disease (AD) and other neurodegenerative diseases, today announces a new epigenetics collaboration with Sheffield Hallam University.

4 Mar 2024

Nerve overgrowth identified as cause of pain in recurring UTIs

A perplexing problem for people with recurring urinary tract infections (UTIs) is persistent pain, even after antibiotics have successfully cleared the bacteria.

1 Mar 2024

Rare gene mutations in hereditary Alzheimer's disease disrupt amyloid production, study shows

A University of Kansas study of rare gene mutations that cause hereditary Alzheimer's disease shows these mutations disrupt production of a small sticky protein called amyloid.

29 Feb 2024

PharmaKure announces epigenetics collaboration with Sheffield Hallam University to understand mechanisms of Alzheimer’s Diseases

New collaboration will enhance ability to identify those more at risk of developing brain diseases to enable earlier interventions.

From PharmaKure 29 Feb 2024

Developing a prognostic model for bladder urothelial cancer using oxidative stress signatures

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 3, entitled, "Prognostic model development and molecular subtypes identification in bladder urothelial cancer by oxidative stress signatures."

28 Feb 2024

Brain waves drive waste removal during sleep, study finds

There lies a paradox in sleep. Its apparent tranquility juxtaposes with the brain's bustling activity. The night is still, but the brain is far from dormant.

28 Feb 2024

New lung cell atlas unveils pathways to lung adenocarcinoma development

Researchers at The University of Texas MD Anderson Cancer Center built a new atlas of lung cells, uncovering new cellular pathways and precursors in the development of lung adenocarcinoma, the most common type of lung cancer.

28 Feb 2024

Calcium crystal deposits linked to worsening knee osteoarthritis, study finds

Knee osteoarthritis (OA) is the most common form of arthritis, affecting approximately 600 million people worldwide and 34 million people in the U.S.

28 Feb 2024

Anti-cancer drug shows promise in treating brain injuries after stroke

A study by the Institut de Neurociències of the UAB (INc-UAB) demonstrates in animal models the benefits of vorinostat after having suffered a stroke.

28 Feb 2024

Genetic studies shed light on hypertension risk but fall short of revealing new treatments

Genetic variant research in hypertension has identified numerous associations but is unlikely to yield new treatments, emphasizing the gap between scientific discovery and clinical application.

27 Feb 2024

Study uncovers the anti-aging role of vitamin D and vitamin D receptor in Drosophila midgut model

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 3, entitled, "The anti-aging effect of vitamin D and vitamin D receptor in Drosophila midgut."

27 Feb 2024

Revolutionary stem cell culture method produces full model of human central nervous system

The first stem cell culture method that produces a full model of the early stages of the human central nervous system has been developed by a team of engineers and biologists at the University of Michigan, the Weizmann Institute of Science, and the University of Pennsylvania.

26 Feb 2024

Novel insights into pathologies of diabetic cardiomyopathy, hippocampal neurotoxicity, and Alzheimer’s

DCM is the leading cause of heart failure in patients with chronic diabetes. However, the underlying mechanisms of DCM are poorly understood, and treatment options are limited.

26 Feb 2024

Study unveils role of dopamine and serotonin in social behavior

In a study in today's (Monday Feb. 26) Nature Human Behavior, scientists delve into the world of chemical neuromodulators in the human brain, specifically dopamine and serotonin, to reveal their role in social behavior.

26 Feb 2024

Study reveals pivotal insights into the progression of Parkinson's disease

Parkinson's disease, the second most common type of progressive dementia after Alzheimer's disease, affects nearly 1 million people in the U.S. and an estimated 10 million individuals worldwide.

24 Feb 2024

Blood test rivals spinal fluid analysis in Alzheimer's detection

A study reveals blood test %p-tau217 matches or surpasses CSF tests in detecting Alzheimer's disease pathology, offering a less invasive, equally accurate alternative for diagnosis across various stages.

22 Feb 2024

Understanding and addressing neurodevelopmental challenges in congenital heart disease

More than a decade of new knowledge about neurodevelopmental risk in people with congenital heart disease has changed the thinking about who is most at risk and the factors that impact neurological development, learning, emotions and behaviors, according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation.

22 Feb 2024

Pathology News and Research

Further Reading

Deciphering the role of GPCRs in obesity pathology for drug development

Scientists take the first step toward early diagnosis of metastasis formation

Researchers discover a noninvasive, low-cost test to detect oral cancer

PharmaKure partners with Sheffield Hallam University to develop epigenetic markers for Alzheimer’s disease prediction

Nerve overgrowth identified as cause of pain in recurring UTIs

Rare gene mutations in hereditary Alzheimer's disease disrupt amyloid production, study shows

PharmaKure announces epigenetics collaboration with Sheffield Hallam University to understand mechanisms of Alzheimer’s Diseases

Developing a prognostic model for bladder urothelial cancer using oxidative stress signatures

Brain waves drive waste removal during sleep, study finds

New lung cell atlas unveils pathways to lung adenocarcinoma development

Calcium crystal deposits linked to worsening knee osteoarthritis, study finds

Anti-cancer drug shows promise in treating brain injuries after stroke

Genetic studies shed light on hypertension risk but fall short of revealing new treatments

Study uncovers the anti-aging role of vitamin D and vitamin D receptor in Drosophila midgut model

Revolutionary stem cell culture method produces full model of human central nervous system

Novel insights into pathologies of diabetic cardiomyopathy, hippocampal neurotoxicity, and Alzheimer’s

Study unveils role of dopamine and serotonin in social behavior

Study reveals pivotal insights into the progression of Parkinson's disease

Blood test rivals spinal fluid analysis in Alzheimer's detection

Understanding and addressing neurodevelopmental challenges in congenital heart disease

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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