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Experimental study shows beneficial effects of Vardenafil on NSAID-induced gastric ulcer

19. November 2009 00:54
Indomethacin has been proved by epidemiological and experimental studies to be closely associated with peptic ulcer development. Vardenafil is a potent phosphodiesterase 5 inhibitor and its effects on the gastric mucosa havenot been reported. [More]

Study: Short-term use of COX-2 inhibitors may help prevent gastric cancer

29. October 2009 03:17
Elevated expression of COX-2 is observed in a wide variety of human malignancies, including gastric cancer. Long-term high dose COX-2 inhibitors can inhibit gastric carcinogenesis in animal models, but the possible life-threatening cardiovascular adverse events limit its popular application. Therefore, it is important to evaluate the optimal intervention point of COX-2 inhibitors for inhibiting H. pylori-associated gastric carcinogenesis. [More]

Shire receives European approval for FOSRENOL

28. October 2009 05:19
Shire plc, the global specialty biopharmaceutical company, today announced it has received approval through the European Mutual Recognition Procedure for an extension to the current indication for FOSRENOL(R) (lanthanum carbonate), paving the way to make the non-calcium, non-resin phosphate binder available throughout the EU to control hyperphosphataemia in chronic kidney disease (CKD) patients who are not on dialysis with a serum phosphorus level greather than or equal to 1.78mmol/L (5.5mg/dL). [More]

University neurologists launch multiple sclerosis research study

24. October 2009 01:21
Neurologists at the University at Buffalo are beginning a research study that could overturn the prevailing wisdom on the cause of multiple sclerosis (MS). [More]

Incisionless operation for stomach ulcers may soon move into human trials

15. October 2009 04:54
An incisionless operation to patch stomach ulcers and potentially other perforations in the digestive tract may soon move into human trials at the Mayo Clinic in Rochester, MN. Clinical investigators reported on their research experience at the 95th annual Clinical Congress of the American College of Surgeons. [More]

Posted in: Medical Procedure News | Medical Condition News

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Shire publishes efficacy study results of FOSRENOL and Renagel

7. October 2009 07:58
Shire plc, the global specialty biopharmaceutical company, today announces the publication in Clinical Nephrology of findings from a head-to-head clinical study comparing the efficacy of two non-calcium based phosphate binders, FOSRENOL(R) (lanthanum carbonate) and sevelamer hydrochloride (Genzyme's Renagel(R)) in chronic kidney disease (CKD) patients on haemodialysis. [More]

Careful follow-up after eradication therapy for peptic ulcer needed

25. September 2009 11:41
Although it has been demonstrated that Helicobacter pylori causes gastric cancer, it is still controversial that whether H. pylori eradication therapy is effective in primary prevention of gastric cancer. This is especially important for Yamagata Prefecture, a region of Japan with the second highest incidence of gastric cancer in the world. [More]

Results from COGENT clinical trial presented at TCT symposium

25. September 2009 05:59
Results from a late breaking clinical trial called COGENT demonstrate that the combination of giving patients clopidogrel, a blood thinner commonly prescribed to patients with cardiovascular disease, and stomach medicines such as omeprazole, known as proton pump inhibitors (PPIs), did not lead to adverse events, as some prior studies had suggested. [More]

Posted in: Drug Trial News

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GI Company's Phase II study demonstrates safety of rhITF oral spray formulation

10. September 2009 09:32
Published today, as an original investigation, in the peer-reviewed Journal of Clinical Oncology, are statistically significant Phase II clinical results of The GI Company's lead clinical compound, rhITF (recombinant human Intestinal Trefoil Factor) oral spray. The article is titled, "A Phase II, Randomized, Double-blind, Placebo-Controlled Study of rhITF Oral Spray for Prevention of Oral Mucositis in Colorectal Cancer Patients Receiving 5-Fluorouracil-based Chemotherapy." [More]

Initial results of the CURRENT-OASIS 7 clinical trial due for release

30. August 2009 23:38
Today, the OASIS study group will present initial results of the CURRENT-OASIS 7 clinical trial at the European Society of Cardiology congress in Barcelona. Sanofi-aventis and Bristol-Myers Squibb, co-commercialization and co-development partners for PLAVIX(clopidogrel bisulfate), were sponsors of the study. [More]

FDA issues final approval for manufacturing and marketing Ranbaxy's Glycopyrrolate tablets

25. August 2009 02:11
Ranbaxy Pharmaceuticals Inc. (RPI), a wholly owned subsidiary of Ranbaxy Laboratories Limited (RLL), announced today that RLL has received approval from the U.S. Food and Drug Administration to manufacture and market Glycopyrrolate Tablets USP, 1 mg and 2 mg. [More]

Posted in: Pharmaceutical News

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Peptic ulcer bacterium alters the body's defence system

30. June 2009 03:40
Helicobacter pylori survives in the body by manipulating important immune system cells. This is shown in a thesis from the Sahlgrenska Academy, University of Gothenburg, Sweden. The discovery may lead to new treatments against the common peptic ulcer bacterium. [More]

Posted in: Medical Research News

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Costs of digestive diseases grown to more than $141 billion a year

10. February 2009 22:45
Digestive, liver and pancreatic diseases result in more than 100 million outpatient visits and 13 million hospitalizations annually at a cost of $141.8 billion. [More]

An ideal therapy for peptic ulcer disease

11. November 2008 23:03
Since the discovery of the etiological role of Helicobacter pylori (H pylori) in peptic ulcer disease, its eradication became the main objective of therapy, and several treatment regimens were developed. [More]

Posted in: Medical Research News

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Free drug samples may end up costing uninsured more

7. September 2008 20:55
Free drug samples provided to physicians by pharmaceutical companies could actually be costing uninsured patients more in the long run, according to a study done by researchers at Wake Forest University Baptist Medical Center and colleagues. [More]

Posted in: Pharmaceutical News

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