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Researchers are developing compounds to combat causative agents of periodontitis

Researchers are developing compounds to combat causative agents of periodontitis

A total 12 million Germans suffer from periodontitis. If the inflammation remains untreated, this could lead to tooth loss. However, it is also suspected of triggering many other diseases, like cardiopulmonary diseases. Researchers are studying the interactions, and developing compounds to combat the causative agents. [More]
Diet may influence susceptibility to autoinflammatory bone disease in at-risk individuals

Diet may influence susceptibility to autoinflammatory bone disease in at-risk individuals

Diet-induced changes in the gut's bacterial ecosystem can alter susceptibility to an autoinflammatory bone disease by modifying the immune response, St. Jude Children's Research Hospital scientists reported. The findings appeared September 28 as an advanced online publication of the scientific journal Nature. [More]
Study links gum disease to lung disease, cancer and heart failure

Study links gum disease to lung disease, cancer and heart failure

Most people are very familiar with the reality that, if they don't practice regular brushing and overall good dental hygiene, they are at risk for developing gum disease. Less well known is the full extent of the potential harm caused by gum disease. [More]
Modulation of B cells may effectively treat symptoms of type 2 diabetes and periodontitis

Modulation of B cells may effectively treat symptoms of type 2 diabetes and periodontitis

Going to the dentist isn't fun for anyone, but for those with periodontal disease related to type 2 diabetes, a new research discovery may have them smiling. [More]
Non-surgical gum disease treatment reduces thickness of wall of arteries

Non-surgical gum disease treatment reduces thickness of wall of arteries

A simple non-surgical gum disease treatment markedly reduces the thickness of the wall of the arteries, a risk factor for heart disease, according to a first of its kind study among Aboriginal Australians. [More]
New framework for monitoring oral cancer development, progression, recurrence

New framework for monitoring oral cancer development, progression, recurrence

Each year, approximately 22,000 Americans are diagnosed with oral cancer. The five-year survival rate of 40% in the U.S. is one of the lowest of the major cancers, and it has not improved in the past 40 years. [More]
Red wine could potentially help prevent cavities

Red wine could potentially help prevent cavities

For anyone searching for another reason to enjoy a glass of red wine with dinner, here's a good one: A new study has found that red wine, as well as grape seed extract, could potentially help prevent cavities. [More]
New drug offers promising possibility for treating adults with periodontitis

New drug offers promising possibility for treating adults with periodontitis

Nearly half of all adults in the United States suffer from the gum disease periodontitis, and 8.5 percent have a severe form that can raise the risk of heart disease, diabetes, arthritis and pregnancy complications. [More]
Oral health: The gateway to your overall health

Oral health: The gateway to your overall health

If the eyes are the windows to your soul, then your mouth is the gateway to your overall health. Research has found a surprising number of links between the state of your oral health and your overall health. [More]
Interleukin receives conditional approval to offer results of PerioPredict genetic risk test

Interleukin receives conditional approval to offer results of PerioPredict genetic risk test

Interleukin Genetics, Inc. today announced it has received conditional approval from the New York State Department of Health to offer, process and report the results of the PerioPredict™ Genetic Risk Test for periodontal disease. [More]
TG2 protein is a key mediator in Porphyromonas gingivalis infection, study finds

TG2 protein is a key mediator in Porphyromonas gingivalis infection, study finds

Scientists at Forsyth, along with a colleague from Northwestern University, have discovered that the protein, Transgultaminase 2 (TG2), is a key component in the process of gum disease. TG2 is widely distributed inside and outside of human cells. The scientists found that blocking some associations of TG2 prevents the bacteria Porphyromonas gingivalis (PG) from adhering to cells. This insight may one day help lead to novel therapies to prevent gum disease caused by PG. [More]
CUMC researchers devise new system for classifying periodontal disease

CUMC researchers devise new system for classifying periodontal disease

Researchers at Columbia University Medical Center have devised a new system for classifying periodontal disease based on the genetic signature of affected tissue, rather than on clinical signs and symptoms. The new classification system, the first of its kind, may allow for earlier detection and more individualized treatment of severe periodontitis, before loss of teeth and supportive bone occurs. [More]
Tooth loss associated with depression and anxiety, study finds

Tooth loss associated with depression and anxiety, study finds

Today, at the 43rd Annual Meeting & Exhibition of the American Association for Dental Research, held in conjunction with the 38th Annual Meeting of the Canadian Association for Dental Research, R. Constance Wiener, from West Virginia University, Morgantown, will present a research study titled "Association of Tooth Loss and Depression and Anxiety." [More]
Twin brains reveal similar progressions of neuropathological changes

Twin brains reveal similar progressions of neuropathological changes

Despite widespread use of a single term, Alzheimer's disease is actually a diverse collection of diseases, symptoms and pathological changes. [More]
Researchers discover how byproducts from bacteria prevalent in gum disease incite growth of deadly tumors

Researchers discover how byproducts from bacteria prevalent in gum disease incite growth of deadly tumors

Researchers from Case Western Reserve University have discovered how byproducts in the form of small fatty acids from two bacteria prevalent in gum disease incite the growth of deadly Kaposi's sarcoma-related (KS) lesions and tumors in the mouth. [More]
Researchers discover 'microbial Pompeii' preserved on teeth of skeletons around 1,000 years old

Researchers discover 'microbial Pompeii' preserved on teeth of skeletons around 1,000 years old

An international team of researchers have discovered a 'microbial Pompeii' preserved on the teeth of skeletons around 1,000 years old. The key to the discovery is the dental calculus (plaque) which preserves bacteria and microscopic particles of food on the surfaces of teeth, effectively creating a mineral tomb for microbiomes. [More]
Nonsurgical treatment of periodontal disease does not improve glycemic control in patients with diabetes

Nonsurgical treatment of periodontal disease does not improve glycemic control in patients with diabetes

A recent study published in the Journal of the American Medical Association (JAMA) found that nonsurgical treatment of periodontal disease does not improve glycemic control in patients with type 2 diabetes. [More]
Poor oral hygiene, excess sugar consumption linked to heart disease

Poor oral hygiene, excess sugar consumption linked to heart disease

The association between poor oral health and increased risk of cardiovascular disease should make the reduction of sugars such as those contained in junk food, particularly fizzy drinks, an important health policy target, say experts writing in the Journal of the Royal Society of Medicine. [More]
ACOEM urges employers to respond to the impact of diabetes on worker health and productivity

ACOEM urges employers to respond to the impact of diabetes on worker health and productivity

In recognition of November as National Diabetes Month, the American College of Occupational and Environmental Medicine (ACOEM) is urging employers to identify and respond to the impact of diabetes on worker health and productivity. [More]
Research findings offer new therapeutic paradigm for periodontal disease

Research findings offer new therapeutic paradigm for periodontal disease

The red, swollen and painful gums and bone destruction of periodontal disease could be effectively treated by beckoning the right kind of immune system cells to the inflamed tissues, according to a new animal study conducted by researchers at the University of Pittsburgh. [More]