Perioperative News and Research

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Tiam1 inhibition mitigates morphine tolerance and hyperalgesia in mouse model

Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems -; prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same pain relief, and paradoxically, prolonged use also can create an extreme sensitivity to pain, called hyperalgesia.

9 Apr 2024

Smartphone app and health coach combo improves surgical outcomes

Coupling a smart phone app with a real-life health coach appears to be key to helping patients adhere to pre-surgical preparation and post-surgical recovery guidance and improving surgical outcomes, according to new findings led by UPMC and University of Pittsburgh School of Medicine physician-scientists.

4 Apr 2024

NCCN updates treatment guidelines for high-incidence cancers

The National Comprehensive Cancer Network is announcing several new updates to the cancer treatment practices listed in the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines).

14 Mar 2024

Robotic-assisted surgery for gallbladder cancer found to be as effective as traditional methods

Each year, approximately 2,000 people die annually of gallbladder cancer (GBC) in the U.S., with only one in five cases diagnosed at an early stage. With GBC rated as the first biliary tract cancer and the 17th most deadly cancer worldwide, pressing attention for proper management of disease must be addressed.

5 Mar 2024

Complications during pregnancy linked to higher risk of heart disease and stroke later in life

Heart disease is the leading cause of death among women, and women who have complications during pregnancy, such as high blood pressure or gestational diabetes, have a significantly higher risk of heart disease and stroke later in life, according to a new scientific statement from the American Heart Association, published today in Circulation, the Association's flagship peer-reviewed journal.

12 Feb 2024

Comparing perioperative differences: Sleeve gastrectomy vs. Roux-en-Y gastric bypass

Study compares laparoscopic sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) in obese patients, finding both procedures have low, comparable perioperative risks and complications, challenging the criteria for selecting between the two surgeries.

1 Feb 2024

New scientific statement outlines recommendations for diagnosing, managing cerebral venous thrombosis

A new scientific statement from the American Heart Association emphasizes the need to increase patients' and physicians' awareness of cerebral venous thrombosis (CVT) to improve the recognition of this condition and initiate prompt medical treatment.

29 Jan 2024

Study identifies risk factors for deadly blood clots after lung cancer surgery

In patients who undergo pulmonary resection for lung cancer, a major potential postoperative complication is venous thromboembolism (VTE)-;a condition that develops when a blood clot forms in a vein-;which can lead to part of the clot breaking off and lodging in the lung, resulting in a pulmonary embolism (PE).

29 Jan 2024

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Currently used Food and Drug Administration-approved transplant drugs -; with the addition of an also already FDA-approved complement inhibitor -; are the optimal immunosuppression regimen for pig-to-human kidney transplants, according to a landmark discovery by University of Alabama at Birmingham investigators.

25 Jan 2024

FDA-approved drug may help to decrease pain after surgery, study finds

Researchers in the Department of Anesthesia and Perioperative Medicine at the Medical University of South Carolina (MUSC) have found that an FDA-approved drug may help to decrease pain after surgery.

12 Jan 2024

Precision surgery, powered by prediction: Optimizing patient care with the best risk scores

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Risk prediction models are an important part of assessing operative mortality and postoperative complication rates in current cardiac surgery practice.

5 Jan 2024

New study provides comprehensive picture of perioperative cardiac arrest in the UK

A new study ‒ that has examined all cardiac arrests occurring during or soon after surgery in more than 300 UK hospitals over a one-year period ‒ has identified that this extremely dangerous and often fatal event occurs in 3 per 10,000 surgeries requiring anesthesia.

16 Nov 2023

$3.4 million grant awarded to identify therapeutic treatments for acute respiratory distress syndrome

A four-year, $3.4 million grant to investigate molecular mechanisms and therapeutic treatments for acute respiratory distress syndrome (ARDS) has been awarded to UTHealth Houston researchers by the National Heart, Lung, and Blood Institute, part of the National Institutes of Health.

26 Oct 2023

Perioperative durvalumab may change standard-of-care for patients with resectable lung cancer

A regimen of pre-surgical immunotherapy and chemotherapy followed by post-surgical immunotherapy significantly improved event-free survival (EFS) and pathologic complete response (pCR) rates compared to chemotherapy alone for patients with operable non-small cell lung cancer (NSCLC), according to results of a Phase III trial reported by researchers at The University of Texas MD Anderson Cancer Center.

24 Oct 2023

Perioperative immunotherapy improves event-free survival in resectable early-stage lung cancer

Compared with pre-surgical (neoadjuvant) chemotherapy alone, adding perioperative immunotherapy – given before and after surgery – significantly improved event-free survival (EFS) in patients with resectable early-stage non-small cell lung cancer (NSCLC).

22 Oct 2023

More walking before surgery reduces postoperative complications

Women more likely than men to develop depression after traumatic brain injury

Women are nearly 50% more likely than men to develop depression after suffering a concussion or other traumatic brain injury (TBI), according to an analysis of nine studies and nearly 700,000 people presented at the ANESTHESIOLOGY 2023 annual meeting.

16 Oct 2023

Perioperative News and Research

Tiam1 inhibition mitigates morphine tolerance and hyperalgesia in mouse model

Smartphone app and health coach combo improves surgical outcomes

NCCN updates treatment guidelines for high-incidence cancers

Robotic-assisted surgery for gallbladder cancer found to be as effective as traditional methods

Complications during pregnancy linked to higher risk of heart disease and stroke later in life

Comparing perioperative differences: Sleeve gastrectomy vs. Roux-en-Y gastric bypass

New scientific statement outlines recommendations for diagnosing, managing cerebral venous thrombosis

Study identifies risk factors for deadly blood clots after lung cancer surgery

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

FDA-approved drug may help to decrease pain after surgery, study finds

Precision surgery, powered by prediction: Optimizing patient care with the best risk scores

New study provides comprehensive picture of perioperative cardiac arrest in the UK

$3.4 million grant awarded to identify therapeutic treatments for acute respiratory distress syndrome

Perioperative durvalumab may change standard-of-care for patients with resectable lung cancer

Perioperative immunotherapy improves event-free survival in resectable early-stage lung cancer

More walking before surgery reduces postoperative complications

Women more likely than men to develop depression after traumatic brain injury

Two simple solutions could help prevent postpartum hemorrhage

AI-powered unbiased pain detection system holds promise for improving patient care

Virtual reality can help calm caregivers of surgery-bound children

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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