Periostin News and Research

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Periostin may be a novel therapeutic target for treating esophageal squamous cell carcinoma

Esophageal squamous cell carcinoma (ESCC) accounts for around 90% of esophageal cancers, especially in East Asia.

9 Apr 2024

Brain natriuretic peptide plays a role in activating atopic dermatitis

Researchers from North Carolina State University have pinpointed a particular peptide's role in activating atopic dermatitis, or eczema. The work could lead to more effective treatments for the condition.

19 Oct 2023

New device for diagnosing bone fragility approved for marketing in the Europe

A new device for diagnosing bone fragility invented by the University Hospitals of Geneva and the University of Geneva has been approved for marketing in the European Economic Area and Switzerland.

20 Sep 2022

Boehringer Ingelheim acquires Northern Biologics to expand cancer immunology portfolio

Boehringer Ingelheim today announced the acquisition of Northern Biologics Inc., a wholly owned subsidiary of Northern LP. By acquiring this entity, which focuses on therapeutic antibodies targeting the tumor microenvironment, Boehringer Ingelheim is now positioned at the forefront of the stromal biology space - an emerging area in cancer immunology.

From Boehringer Ingelheim International GmbH 18 May 2020

Common protein in skin can directly activate itch-associated neurons

A commonly expressed protein in skin - periostin - can directly activate itch-associated neurons in the skin, according to new research from North Carolina State University.

7 Apr 2020

Patients with severe asthma may benefit from newly developed targeted treatments

In a novel study, researchers succeeded in identifying patients with a form of severe asthma (type 2 endotype) by measuring periostin concentrations in their airways.

23 Oct 2018

LJI study reveals key player that promotes skin inflammation in atopic dermatitis

Severe eczema, also known as atopic dermatitis, is a chronic inflammatory skin condition that is driven by an allergic reaction. In their latest study, researchers at La Jolla Institute reveal an important player that promotes skin inflammation in atopic dermatitis and the characteristic thickening of the skin.

18 Jan 2018

$Blood tests help predict fracture risk in postmenopausal women$

Blood tests help predict fracture risk in postmenopausal women

In a study published in the Journal of Bone and Mineral Research, blood tests that detect fragments of a protein secreted by bone cells helped to predict fracture risk in postmenopausal women, independently of bone mineral density, bone turnover markers, and other measures of bone health.

16 Aug 2017

New study aims to prevent chronic cardiac failure

Researchers at Osaka University clarified that the cell adhesion inhibition of periostin1 damages myocardinal cells, inducing compromised cardiac myocyte contractile force and myocytes death, leading to the onset of cardiac failure after AMI through the administration of periostin neutralizing antibodies they had developed on their own.

26 Jan 2016

Researchers identify new regulatory pathway that may play vital role in basal-like breast cancer

Researchers have identified a new regulatory pathway that may play an important role in basal-like breast cancer (BLBC), a particularly aggressive form of breast cancer often referred to as "triple negative." This pathway may serve as a target for the development of an effective therapeutic.

5 Nov 2015

MedImmune to present Phase IIb asthma data on benralizumab and tralokinumab at ATS conference

AstraZeneca today announced that MedImmune, its global biologics research and development arm, will present Phase IIb data on two novel investigational molecules – benralizumab and tralokinumab – at the upcoming American Thoracic Society 2014 International Conference being held in San Diego, California, 16-21 May.

14 May 2014

Researchers solve long-standing mystery behind dormant disseminated breast tumor cells

The long-standing mystery behind dormant disseminated breast tumor cells and what activates them after years and even decades of latency may have been solved. Researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) have identified the microenvironment surrounding microvasculature - the small blood vessels that transport blood within tissues - as a niche where dormant cancer cells reside. When these blood vessels begin to sprout, the new tips produce molecules that transform dormant cancer cells into metastatic tumors.

4 Jun 2013

Biomarkers predict progressive spinal damage in ankylosing spondylitis

German researchers have discovered five biomarkers that may predict the progression of structural damage in the spine of patients with ankylosing spondylitis who are already at high risk for disease progression.

8 Jun 2012

Study identifies 5 biomarkers that may predict progression of spinal damage in AS patients

A new study presented today at EULAR 2012, the Annual Congress of the European League Against Rheumatism, has identified five biomarkers that may predict the progression of structural damage in the spine of patients with Ankylosing Spondylitis (AS) who are already at high risk of disease progression.

7 Jun 2012

Periostin News and Research

Periostin may be a novel therapeutic target for treating esophageal squamous cell carcinoma

Brain natriuretic peptide plays a role in activating atopic dermatitis

New device for diagnosing bone fragility approved for marketing in the Europe

Boehringer Ingelheim acquires Northern Biologics to expand cancer immunology portfolio

Common protein in skin can directly activate itch-associated neurons

Patients with severe asthma may benefit from newly developed targeted treatments

LJI study reveals key player that promotes skin inflammation in atopic dermatitis

Blood tests help predict fracture risk in postmenopausal women

New study aims to prevent chronic cardiac failure

Researchers identify new regulatory pathway that may play vital role in basal-like breast cancer

MedImmune to present Phase IIb asthma data on benralizumab and tralokinumab at ATS conference

Researchers solve long-standing mystery behind dormant disseminated breast tumor cells

Biomarkers predict progressive spinal damage in ankylosing spondylitis

Study identifies 5 biomarkers that may predict progression of spinal damage in AS patients

Growth factor enhances heart regeneration, improves heart function without need for cardiac stem cells

Heart patches that stimulate regeneration

Special patch improves heart function after heart attacks

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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