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New research links mutations in TEX11 gene to some cases of male infertility

New research links mutations in TEX11 gene to some cases of male infertility

In the most severe form of male infertility, men do not make any measurable levels of sperm. This condition, called azoospermia, affects approximately 1 percent of the male population and is responsible for about a sixth of cases of male infertility. [More]
ASHG declares 2015 recipients of annual Award for Excellence in Human Genetics Education

ASHG declares 2015 recipients of annual Award for Excellence in Human Genetics Education

The American Society of Human Genetics (ASHG) has named Robert L. Nussbaum, M.D., chief medical officer of invitae and clinical professor of medicine (volunteer) at the University of California, San Francisco (UCSF); Roderick R. McInnes, CM, M.D., Ph.D., director of the Lady Davis Institute at the Jewish General Hospital and Alva chair in human genetics, Canada Research chair in neurogenetics, and professor of human genetics and biochemistry at McGill University; and Huntington F. Willard, Ph.D., president and director of the Marine Biological Laboratory and professor of human genetics at the University of Chicago; as the 2015 recipients of its annual Award for Excellence in Human Genetics Education. [More]
Kalorama Information: NGS diagnostics can detect any number of genetic variants

Kalorama Information: NGS diagnostics can detect any number of genetic variants

Next generation sequencing may be able to bypass some of the downside of molecular testing and in doing so earn its place in clinical testing, according to Kalorama Information. [More]
SLU researchers find way to stop growth of cancer cells by targeting the Warburg Effect

SLU researchers find way to stop growth of cancer cells by targeting the Warburg Effect

In research published in Cancer Cell, Thomas Burris, Ph.D., chair of pharmacology and physiology at Saint Louis University, has, for the first time, found a way to stop cancer cell growth by targeting the Warburg Effect, a trait of cancer cell metabolism that scientists have been eager to exploit. [More]
Immune Pharmaceuticals begins bertilimumab Phase II clinical trials in Bullous Pemphigoid, Ulcerative Colitis

Immune Pharmaceuticals begins bertilimumab Phase II clinical trials in Bullous Pemphigoid, Ulcerative Colitis

Immune Pharmaceuticals Inc. announced today that it has initiated its Phase II Ulcerative Colitis clinical trial and is scheduled to initiate its Phase II Bullous Pemphigoid clinical trial on July 1, 2015. Study Initiation is the training of hospital staff to allow for patient screening and immediate patient enrollment into the clinical trial upon selection. [More]
Biontech, Siemens enter into strategic collaboration on manufacture of personalized cancer vaccines

Biontech, Siemens enter into strategic collaboration on manufacture of personalized cancer vaccines

Siemens and BioNTech AG, a fully integrated biotechnology company developing truly personalized cancer immunotherapies, have entered into a strategic collaboration. [More]
Myriad Genetics, Chris4Life launch educational campaign to teach individuals about risk of hereditary cancer

Myriad Genetics, Chris4Life launch educational campaign to teach individuals about risk of hereditary cancer

Chris4Life Colon Cancer Foundation, a Washington, D.C.-based national non-profit organization, and Myriad Genetics, a leader in personalized medicine, today announced their “What’s Your History” family history week (June 24-30, 2015). [More]
Cytokine levels may help distinguish patients with suicidality

Cytokine levels may help distinguish patients with suicidality

One American dies from suicide every 12.8 minutes, making suicide the tenth leading cause of death in the United States according to the American Foundation for Suicide Prevention. [More]
Scientists identify four melanoma subtypes that share common 'downstream' signaling pathways

Scientists identify four melanoma subtypes that share common 'downstream' signaling pathways

Cutaneous melanoma, the most deadly form of skin cancer, is now believed to be divided into four distinct genomic subtypes, say researchers at The University of Texas MD Anderson Cancer Center, a finding that could prove valuable in the ever-increasing pursuit of personalized medicine. [More]
Florida Institute finalizes funding agreement with TransGenex Nanobiotech

Florida Institute finalizes funding agreement with TransGenex Nanobiotech

The Florida Institute for the Commercialization of Public Research announced today that it has finalized a funding agreement with TransGenex Nanobiotech, Inc., a company that is developing nano-scale technologies for novel, cost-effective diagnostic and therapeutic agents against cancers and other inflammatory diseases. [More]
Cryoport to provide cryogenic logistics solutions to support personalized medicine efforts of CaRE Arthritis

Cryoport to provide cryogenic logistics solutions to support personalized medicine efforts of CaRE Arthritis

Cryoport, Inc., the leading provider of advanced cryogenic logistics solutions for the life sciences industry, serving markets including immunotherapies, stem cells, cell lines, clinical research organizations, vaccine manufacturers, animal health, and reproductive medicine, today announced that the Company is the preferred cryogenic logistics provider to CaRE Arthritis. [More]
Supporting life science innovation: an interview with Ger Brophy, CTO, GE Healthcare Life Sciences

Supporting life science innovation: an interview with Ger Brophy, CTO, GE Healthcare Life Sciences

We are very interested in accessing innovation and technology, but we can't hope to do everything ourselves. One way for us to do this is to set up the Innovation Village, to provide space for entrepreneurs and innovators in South Wales. [More]
Dell extends partnership with TGen to globally expand precision medicine trial for pediatric cancer

Dell extends partnership with TGen to globally expand precision medicine trial for pediatric cancer

Dell today announced its extended partnership with the Translational Genomics Research Institute to help clinical researchers and doctors globally expand the reach and impact of the world's first Food and Drug Administration-approved precision medicine trial for pediatric cancer. [More]
MammaTyper molecular diagnostic test for breast cancer now available in Europe

MammaTyper molecular diagnostic test for breast cancer now available in Europe

BioNTech AG, a fully integrated biotechnology company developing truly personalized cancer immunotherapies and its subsidiary BioNTech Diagnostics GmbH, today announced the launch of MammaTyper, a CE-IVD marked molecular diagnostic test to stratify breast cancer patients by molecular subtyping of routine tumor tissue, for universal use in pathology laboratories. [More]
BioNTech announces launch of MammaTyper test to improve breast cancer treatment

BioNTech announces launch of MammaTyper test to improve breast cancer treatment

BioNTech AG, a fully integrated biotechnology company developing truly personalized cancer immunotherapies and its subsidiary BioNTech Diagnostics GmbH, today announced the launch of MammaTyper, a CE-IVD marked molecular diagnostic test to stratify breast cancer patients by molecular subtyping of routine tumor tissue, for universal use in pathology laboratories. [More]
Simple process for obtaining induced pluripotent stem cells without use of reagents

Simple process for obtaining induced pluripotent stem cells without use of reagents

For their ability to differentiate into other cell types, the embryonic stem cells hold a large potential in the medical industry. Their use, however, poses ethical questions due to the fact that in order to obtain them, it is necessary to destroy the embryo. For this reason, medical researches use the so-called induced pluripotent stem cells (iPSC). In fact, it is possible to reprogram adult cells that can be obtained by simply drawing blood and making them "regress" to a similar state to that of embryonic stem cells. [More]
Researchers examine specific causes of mortality after blood and marrow transplant

Researchers examine specific causes of mortality after blood and marrow transplant

Blood and Marrow Transplantation (BMT) is a potentially curative treatment for patients with leukemia or other life-threating blood diseases. With a goal of increasing survival rates, a research team led by Roswell Park Cancer Institute investigators verified patient outcome data submitted by more than 150 U.S. transplant centers over an 11-year period to the Center for International Blood and Marrow Transplant Research. [More]
DalCor, MHI partner to conduct Phase III clinical trial of investigational cardiovascular drug

DalCor, MHI partner to conduct Phase III clinical trial of investigational cardiovascular drug

DalCor Pharmaceuticals and the Montreal Heart Institute announced today a collaboration in principle to conduct an international Phase III clinical trial which could result in a major clinical advance in cardiovascular personalised medicine. [More]
Rhythm announces initiation of two setmelanotide Phase 2 trials for treatment of PWS, POMC-null obesity

Rhythm announces initiation of two setmelanotide Phase 2 trials for treatment of PWS, POMC-null obesity

Rhythm announced today the initiation of two Phase 2 clinical trials focused on evaluating the safety and effectiveness of setmelanotide (RM-493), the company's novel melanocortin 4 receptor (MC4R) agonist, for the treatment of Prader-Willi Syndrome (PWS) and POMC-null obesity. [More]
Steven Schiff wins NIH Director's Pioneer Award to reduce infant deaths from neonatal sepsis

Steven Schiff wins NIH Director's Pioneer Award to reduce infant deaths from neonatal sepsis

Steven Schiff, professor of neurosurgery and Brush Chair Professor of Engineering in Engineering Science and Mechanics, has received a $4.1 million National Institutes of Health Director's Pioneer Award, for research aimed at reducing the number of infant deaths from neonatal sepsis in developing countries by identifying the roots of infection, from season of birth to home environment. [More]
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