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Curve along edge of tumor may play major role in cancer cell metastasis

Curve along edge of tumor may play major role in cancer cell metastasis

Only a few cells in a cancerous tumor are able to break away and spread to other parts of the body, but the curve along the edge of the tumor may play a large role in activating these tumor-seeding cells, according to a new University of Illinois study. [More]
Certain genetic markers linked with depression can also predict who may benefit from exercise

Certain genetic markers linked with depression can also predict who may benefit from exercise

Call it personalized medicine for depression -- but the prescription in this case is exercise, which University of Florida Health researchers have found helps people with certain genetic traits. [More]
Innovations in pre-clinical MRI: an interview with Priv. Doz. Dr. Dominik von Elverfeldt

Innovations in pre-clinical MRI: an interview with Priv. Doz. Dr. Dominik von Elverfeldt

To me the most exciting aspect of pre-clinical imaging is its broad range, from very basic science up to applied science. You deal with a range of disciplines including biology, chemistry, physics, biochemistry, biophysics, cell biology and of course medicine, as the aim is the translation of research to humans. [More]
Experts focus on scientific complexities of individual and population health at iCOMOS 2016

Experts focus on scientific complexities of individual and population health at iCOMOS 2016

How do we balance the needs for individualized health care with the public health programs serving communities - especially in the context of environmental pollution and climate change? Given a fixed set of resources, maximizing the potential of both is challenging, indeed. [More]
Researchers develop new mathematical model to evaluate best treatment protocol to clear infection

Researchers develop new mathematical model to evaluate best treatment protocol to clear infection

Antibiotic resistance is one of the most challenging problems in modern medicine. A new study by Erida Gjini and Patricia H. Brito from the Instituto Gulbenkian de Ciência, provides a new mathematical model to evaluate the best treatment protocol to clear an infection, by taking into account the role of the host immune system. [More]
Researchers develop new method for identifying DNA mutations in single cancer cell

Researchers develop new method for identifying DNA mutations in single cancer cell

Researchers at The University of Texas MD Anderson Cancer Center have announced a new method for detecting DNA mutations in a single cancer cell versus current technology that analyzes millions of cells which they believe could have important applications for cancer diagnosis and treatment. The results are published in the April 18 online issue of Nature Methods. [More]
Study shows children with rare eye disease have greatest benefit from gene therapy

Study shows children with rare eye disease have greatest benefit from gene therapy

Scientists at Oregon Health & Science University's Casey Eye Institute and Baylor College of Medicine's Cullen Eye Institute published findings from a two-year Phase I clinical trial in the journal Ophthalmology, which showed that children had the greatest benefit from gene therapy for treatment of Leber congenital amaurosis (LCA) or severe early childhood onset retinal degeneration (SECORD). [More]
How will IoT impact healthcare? An interview with David Doherty

How will IoT impact healthcare? An interview with David Doherty

IoT is a term being used to help communicate the complex transition that's happening as Mobile transforms the Internet into a network of devices. The idea of the internet being something we go to and use a mouse to navigate is dead as we now can talk to SIRI on our mobiles to immediately summon Uber cars and buy things from Amazon that will arrive in just a few hours. Welcome to a new world! [More]
Scientists aim to develop latest biosensors for personalized medicine, drug development

Scientists aim to develop latest biosensors for personalized medicine, drug development

Scientists at the Leibniz Institute for Molecular Pharmacology in Berlin-Buch and the California Institute of Technology in Pasadena cooperate in the future for the development of the latest biosensors for usage related to personalized medicine and drug development. [More]
International scientists discuss new treatments for non small cell lung cancer

International scientists discuss new treatments for non small cell lung cancer

More than 30 prominent international scientists gathered to discuss the state-of-the-art, as well as promising future approaches for the treatment of lung cancer at the stunning 17th century Borgo San Luigi, in Monteriggion, in the heart of the Tuscany countryside. [More]
Moffitt study reports that liver metastases have different sensitivities to radiation therapy

Moffitt study reports that liver metastases have different sensitivities to radiation therapy

Radiation is a commonly used therapeutic option to treat liver metastases, with the majority of tumors maintained under control after one year. However, some patients do not respond as well to radiation treatment, and the factors that predict patient outcomes are unclear. Moffitt Cancer Center researchers report that liver metastases have different sensitivities to radiation therapy based on the location of the primary tumor. [More]
Complete genetic map of scleroderma opens door for diagnosis and targeted treatment

Complete genetic map of scleroderma opens door for diagnosis and targeted treatment

Scleroderma is an autoimmune disease that affects one out of every 10,000 people in Europe and North America, mostly middle-aged women, and causes death in a high percentage of cases. [More]
Advances in NMR metabolomics: an interview with Professor Tone F. Bathen

Advances in NMR metabolomics: an interview with Professor Tone F. Bathen

The main objective of our research is to improve and individualize cancer diagnostics and cancer treatment. We try to achieve this through the integrated use of MR technology and the development of data-driven tools to analyze tumors on both a functional and molecular level. [More]
Phenotypic personalized medicine can identify a person's optimal drug, dose combinations

Phenotypic personalized medicine can identify a person's optimal drug, dose combinations

For decades, doctors and scientists have predicted that personalized medicine — tailoring drug doses and combinations to people's specific diseases and body chemistry — would be the future of health care. [More]
Myriad myRisk Hereditary Cancer test identifies 70% more deleterious mutations than BRCA1/2 testing alone

Myriad myRisk Hereditary Cancer test identifies 70% more deleterious mutations than BRCA1/2 testing alone

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, working in collaboration with researchers from the Harvard Medical School, today announced that the Journal of Clinical Oncology has published a paper showing the frequency of germline mutations in 25 cancer susceptibility genes among patients with breast cancer. [More]
Oregon's new birth control law could improve access to all forms of contraception

Oregon's new birth control law could improve access to all forms of contraception

Researchers at Oregon Health & Science University, University of Minnesota School of Public Health and George Mason University applaud Oregon's new birth control law which allows women age 18 or older to obtain some methods of hormonal contraception directly from pharmacies, without having to visit a prescribing clinician, yet note how the law could go even further to improve access to all forms of contraception, according to a viewpoint article published in the Journal of the American Medical Association today. [More]
New drug regimens could significantly improve treatment for tuberculosis

New drug regimens could significantly improve treatment for tuberculosis

Researchers from UCLA and Shanghai Jiao Tong University have made an important step toward a substantially faster and more effective treatment for tuberculosis, which infects some 10 million people and causes 1.5 million deaths each year. [More]
Personalized medicine promises better treatment options for cystic fibrosis patients

Personalized medicine promises better treatment options for cystic fibrosis patients

For a highly variable disease like cystic fibrosis, personalized medicine promises treatments based on individual factors, down to the molecular level. This promise is especially alluring for the treatment of children with cystic fibrosis, who are at particular risk for complications that could affect them throughout their lives. [More]
Researchers develop metastasis-on-a-chip system to advance cancer investigation, drug discovery

Researchers develop metastasis-on-a-chip system to advance cancer investigation, drug discovery

Advances in personalized medicine allow doctors to select the most promising drugs for certain types of malignant tumors. [More]
Scientists find evidence that amyloid fibrils adopt several distinct architectures in human, animal tissues

Scientists find evidence that amyloid fibrils adopt several distinct architectures in human, animal tissues

Formation of amyloid fibrils is a characteristic feature of neurogenerative diseases like Alzheimer's. As published in the journal Angewandte Chemie, German and American scientists have found evidence that these fibrils adopt several distinct three-dimensional architectures in real patient and animal tissues. [More]
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