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Synthetic sgRNA for CRISPR genome editing

Synthetic sgRNA for CRISPR genome editing

Chemically synthesized single guide RNA is the best way to do CRISPR genome editing. It is more pure than biological methods of creating guide RNAs, like in vitro transcription or plasmids. As a result, sgRNA leads to more consistency and higher quality. [More]
Researchers find strong link between angiotensin receptor autoantibodies and increased risk of frailty

Researchers find strong link between angiotensin receptor autoantibodies and increased risk of frailty

Results of a new study led by Johns Hopkins researchers offer new evidence for a strong link between angiotensin receptor autoantibodies and increased risk of frailty. [More]
3D-printed organ models could aid individualized dosimetry in nuclear medicine

3D-printed organ models could aid individualized dosimetry in nuclear medicine

In nuclear medicine, the goal is to keep radiation exposure at a minimum, while obtaining quality images. [More]
Novel imaging agent can rapidly and accurately detect metastasis of prostate cancer

Novel imaging agent can rapidly and accurately detect metastasis of prostate cancer

New research demonstrates that a novel imaging agent can quickly and accurately detect metastasis of prostate cancer, even in areas where detection has previously been difficult. [More]
New study finds genetic link between Parkinson's disease and cognitive decline

New study finds genetic link between Parkinson's disease and cognitive decline

Although the hallmark symptoms of Parkinson's disease (PD) - such as involuntary shaking, slowness of movement and muscle rigidity - are related to movement, recent evidence has suggested that memory impairment plays an outsized role in diminished quality of life and the burden placed on caregivers. [More]
OHSU scientists identify potential target for preventing and treating Alzheimer's disease

OHSU scientists identify potential target for preventing and treating Alzheimer's disease

A new scientific discovery may provide a future avenue for treatment and prevention of Alzheimer's disease. [More]
Nature Methods publishes comparative study of leading Protein-Protein Interaction Networks

Nature Methods publishes comparative study of leading Protein-Protein Interaction Networks

Nature Methods published (online) a comparative study of leading Protein-Protein Interaction (PPI) Networks. [More]
TGen and City of Hope collaborate to accelerate precision medicine research

TGen and City of Hope collaborate to accelerate precision medicine research

City of Hope, a world-renowned independent research and cancer and diabetes treatment center, and Translational Genomics Research Institute, a leading biomedical research institute, announced today that they have formed an alliance to make precision medicine a reality for patients. [More]
Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

The Allen Institute for Cell Science has released the Allen Cell Collection: the first publicly available collection of gene edited, fluorescently tagged human induced pluripotent stem cells that target key cellular structures with unprecedented clarity. [More]
Drexel researchers one step closer to offering new treatment for chronic wounds

Drexel researchers one step closer to offering new treatment for chronic wounds

Drexel University researchers are one step closer to offering a new treatment for the millions of patients who suffer from slow-healing, chronic wounds. [More]
Inflammatory marker detected in blood tests can better predict risk of death, study suggests

Inflammatory marker detected in blood tests can better predict risk of death, study suggests

A new study looking at deaths from cancer, cardiovascular disease and all causes suggests that an inflammatory marker detected in blood tests in middle-aged adults can better predict the risk of death compared with another similar biomarker. [More]
Veterans Affairs researchers discover alleles of certain genes that offer protection from GWI

Veterans Affairs researchers discover alleles of certain genes that offer protection from GWI

Veterans Affairs researchers have found that certain forms, or alleles, of a gene known to play a key role in the immune system appear to offer protection from Gulf War illness (GWI). Further, they discovered how such protection is manifested in the brain. [More]
Crowdsourcing new prediction tool for better prognosis of metastatic castration-resistant prostate cancer

Crowdsourcing new prediction tool for better prognosis of metastatic castration-resistant prostate cancer

Knowing the likely course of cancer can influence treatment decisions. Now a new prediction model published today in Lancet Oncology offers a more accurate prognosis for a patient's metastatic castration-resistant prostate cancer. [More]
Researchers to explore how in-womb exposure to environmental chemicals may affect childhood obesity

Researchers to explore how in-womb exposure to environmental chemicals may affect childhood obesity

Kaiser Permanente researchers have received a major new grant from the National Institutes of Health to study how exposures to environmental chemicals during pregnancy may influence the risk of obesity and neurodevelopmental disorders in children. [More]
Statins can help prevent first time heart attacks, strokes in adults with cardiovascular risk factors

Statins can help prevent first time heart attacks, strokes in adults with cardiovascular risk factors

Cholesterol-lowering drugs help prevent heart attacks and strokes in adults with cardiovascular risk factors such as high cholesterol, high blood pressure, diabetes and smoking, but have not yet had a heart attack or stroke, according to a large-scale analysis of clinical trial data led by the OHSU Pacific Northwest Evidence-Based Practice Center. [More]
Technion researchers develop new diagnostic technology for improving personalized cancer treatment

Technion researchers develop new diagnostic technology for improving personalized cancer treatment

Using synthetic DNA sequences as the tiniest of barcodes, Technion researchers have developed a new diagnostic technology for determining the suitability of specific anticancer drugs to a specific patient - before treatment even begins. [More]
Personalized medicine may offer solution for treatment of psychiatric disturbances

Personalized medicine may offer solution for treatment of psychiatric disturbances

An ever widening gap is appearing between clinical practice and the treatment prescribed in DSM-5, the standard work on schizophrenia, psychiatrist Jan Dirk Blom will assert in his inaugural lecture on 11 November. [More]
Agendia partners with Cryogene and Mist to distribute breast cancer recurrence assay in the Middle East

Agendia partners with Cryogene and Mist to distribute breast cancer recurrence assay in the Middle East

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, announced today a partnership agreement to distribute the company’s breast cancer recurrence assay, MammaPrint, in the Middle East. [More]
ASH partners with other organizations to address knowledge gaps in AML care

ASH partners with other organizations to address knowledge gaps in AML care

The American Society of Hematology has partnered with several organizations on independent educational programming designed to help address knowledge gaps in the diagnosis and treatment of acute myeloid leukemia (AML). [More]
Scientists use latest sequencing technology to review genetic makeup of ataxias syndrome

Scientists use latest sequencing technology to review genetic makeup of ataxias syndrome

According to a recent study published in JAMA Neurology, Northwestern Medicine scientists have examined more than a century of data of the genetic makeup of ataxias, a neurodegenerative disorder, to better understand the different forms of this devastating disease and how it affects patients. [More]
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