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Genetic testing at UMMC helps doctors identify effective medication for heart stent patients

Genetic testing at UMMC helps doctors identify effective medication for heart stent patients

The University of Maryland Medical Center is now offering a simple genetic test to patients who receive heart stents to determine whether they have a genetic deficiency that affects how they respond to a common drug to prevent blood clots. [More]
ACMG advocates sharing of laboratory and clinical genomic data to improve genetic health care

ACMG advocates sharing of laboratory and clinical genomic data to improve genetic health care

There are an estimated 5,000 - 7,000 rare genetic diseases, each of which can vary dramatically and be caused by a multitude of different genetic changes. [More]
Researchers develop first sensor that can identify IBD and distinguish between two subtypes

Researchers develop first sensor that can identify IBD and distinguish between two subtypes

Researchers have developed the first sensor capable of objectively identifying inflammatory bowel disease (IBD) and distinguishing between its two subtypes. [More]
Targeting Legumain could be promising strategy for treatment of cancer

Targeting Legumain could be promising strategy for treatment of cancer

Legumain (LGMN), or asparaginyl endopeptidase, is a newly identified lysosomal cysteine protease. [More]
Agendia data reveals impact of MammaPrint on adjuvant treatment decisions in breast cancer patients

Agendia data reveals impact of MammaPrint on adjuvant treatment decisions in breast cancer patients

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, has presented new prospective data demonstrating the strong impact of its 70-Gene Breast Cancer Recurrence assay, MammaPrint, and the corresponding 80-Gene Molecular Subtyping Assay BluePrint, in clinical decision-making for patients with early-stage breast cancer in Germany. [More]
Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Diet-related diseases like non-alcoholic fatty liver disease (NAFLD) are known to have a major inflammatory component. [More]
Novel genomics model allows personalized approach to radiation therapy

Novel genomics model allows personalized approach to radiation therapy

Cancer therapeutics is currently in the era of precision medicine - personalized medicine for individual patients based on their tumor biology. [More]
Scientists isolate and characterize therapy-resistant dormant leukemia cells

Scientists isolate and characterize therapy-resistant dormant leukemia cells

Dr. Irmela Jeremias from Helmholtz Zentrum München and her colleagues have succeeded in finding a small population of inactive leukemia cells that is responsible for relapse of the disease. [More]
New technique uses focused ultrasound to detect cancer biomarkers in the blood

New technique uses focused ultrasound to detect cancer biomarkers in the blood

Each year, thousands of Canadian men with prostate cancer undergo biopsies to help their doctors better understand the progression and nature of their disease. It provides vital, sometimes life-saving information, yet cancer researcher John Lewis knows it can be a difficult test to ask of anyone. [More]
New Forsyth study provides new foundation for fighting Sjögren's syndrome

New Forsyth study provides new foundation for fighting Sjögren's syndrome

Sjögren's syndrome is the second most common autoimmune disease affecting four million Americans--yet treatments are limited due to a lack of knowledge about its causes. [More]
Phenotypic Personalized Medicine could surmount treatment challenges for acute lymphoblastic leukemia

Phenotypic Personalized Medicine could surmount treatment challenges for acute lymphoblastic leukemia

A team of UCLA bioengineers has demonstrated that its technology may go a long way toward overcoming the challenges of treatment for acute lymphoblastic leukemia, among the most common types of cancer in children, and has the potential to help doctors personalize drug doses. [More]
New model can simplify process of mixing perfect drug cocktails

New model can simplify process of mixing perfect drug cocktails

Drug cocktails, such as those for treating cancer, are best when the proper ingredients are mixed in the right proportions - just like the alcoholic versions offered at the local bar. [More]
Synthetic sgRNA for CRISPR genome editing

Synthetic sgRNA for CRISPR genome editing

Chemically synthesized single guide RNA is the best way to do CRISPR genome editing. It is more pure than biological methods of creating guide RNAs, like in vitro transcription or plasmids. As a result, sgRNA leads to more consistency and higher quality. [More]
Researchers find strong link between angiotensin receptor autoantibodies and increased risk of frailty

Researchers find strong link between angiotensin receptor autoantibodies and increased risk of frailty

Results of a new study led by Johns Hopkins researchers offer new evidence for a strong link between angiotensin receptor autoantibodies and increased risk of frailty. [More]
3D-printed organ models could aid individualized dosimetry in nuclear medicine

3D-printed organ models could aid individualized dosimetry in nuclear medicine

In nuclear medicine, the goal is to keep radiation exposure at a minimum, while obtaining quality images. [More]
Novel imaging agent can rapidly and accurately detect metastasis of prostate cancer

Novel imaging agent can rapidly and accurately detect metastasis of prostate cancer

New research demonstrates that a novel imaging agent can quickly and accurately detect metastasis of prostate cancer, even in areas where detection has previously been difficult. [More]
New study finds genetic link between Parkinson's disease and cognitive decline

New study finds genetic link between Parkinson's disease and cognitive decline

Although the hallmark symptoms of Parkinson's disease (PD) - such as involuntary shaking, slowness of movement and muscle rigidity - are related to movement, recent evidence has suggested that memory impairment plays an outsized role in diminished quality of life and the burden placed on caregivers. [More]
OHSU scientists identify potential target for preventing and treating Alzheimer's disease

OHSU scientists identify potential target for preventing and treating Alzheimer's disease

A new scientific discovery may provide a future avenue for treatment and prevention of Alzheimer's disease. [More]
Nature Methods publishes comparative study of leading Protein-Protein Interaction Networks

Nature Methods publishes comparative study of leading Protein-Protein Interaction Networks

Nature Methods published (online) a comparative study of leading Protein-Protein Interaction (PPI) Networks. [More]
TGen and City of Hope collaborate to accelerate precision medicine research

TGen and City of Hope collaborate to accelerate precision medicine research

City of Hope, a world-renowned independent research and cancer and diabetes treatment center, and Translational Genomics Research Institute, a leading biomedical research institute, announced today that they have formed an alliance to make precision medicine a reality for patients. [More]
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