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Pharmacology is the study of how chemical substances interact with living systems. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, interactions, toxicology, therapy, and medical applications and antipathogenic capabilities.
MRI-guided focused ultrasound treatment improves quality of life in patients with essential tremor

MRI-guided focused ultrasound treatment improves quality of life in patients with essential tremor

Treatment with MRI-guided focused ultrasound significantly improves tremors and quality of life in patients with essential tremor (ET), the most common movement disorder, according to a study published in the August 25 issue of the New England Journal of Medicine. [More]
Anesthetic administered with nasal spray effective in preventing pain during dental treatment

Anesthetic administered with nasal spray effective in preventing pain during dental treatment

A fear of pain causes many people with dental phobias to avoid or delay needed treatment. In some cases, the injection of a numbing agent can be the most painful part of the visit. [More]
IRB Barcelona review article provides insights into emerging field of shuttle peptides

IRB Barcelona review article provides insights into emerging field of shuttle peptides

IRB Barcelona researchers publish a review article on the emerging field of drug transporters that have the capacity to reach the brain more efficiently. [More]
Novel inhibitory brain receptor reduces seizure-like activity in pubertal mice

Novel inhibitory brain receptor reduces seizure-like activity in pubertal mice

More than half of children with epilepsy outgrow their seizures, yet the mechanism underlying this remission is unknown. [More]
UNC researchers map anxiety circuit in the brain that may explain side effects of antidepressants

UNC researchers map anxiety circuit in the brain that may explain side effects of antidepressants

More than 100 million people worldwide take selective serotonin reuptake inhibitors (SSRIs), such as Prozac and Zoloft, to treat depression, anxiety and related conditions, but these drugs have a common and mysterious side effect: they can worsen anxiety in the first few weeks of use, which leads many patients to stop treatment. [More]
Atomic level analysis reveals how two classes of calcium channel blockers produce different effects

Atomic level analysis reveals how two classes of calcium channel blockers produce different effects

An atomic level analysis has revealed how two classes of calcium channel blockers, widely prescribed for heart disease patients, produce separate therapeutic effects through their actions at different sites on the calcium channel molecule. [More]
New noninvasive treatment option improves quality of life in patients with essential tremor

New noninvasive treatment option improves quality of life in patients with essential tremor

Treatment with MRI-guided focused ultrasound significantly improves tremors and quality of life in patients with essential tremor (ET), the most common movement disorder, according to a study published in the August 25 issue of the New England Journal of Medicine. [More]
TMDU researchers inject gelatin-based gel carrying protein/peptide drugs to trigger bone augmentation

TMDU researchers inject gelatin-based gel carrying protein/peptide drugs to trigger bone augmentation

The part of the jawbone containing tooth sockets is known as alveolar bone, and its loss over time or following dental disease may ultimately result in tooth loss. [More]
Researcher aims to shed new light on inner workings of the retina

Researcher aims to shed new light on inner workings of the retina

One of the more studied parts of the human anatomy, the retina -- the neural layer at the back of the eye that senses light -- still has secrets to reveal. [More]
Research offers new insights into sleep/awake patterns in animals

Research offers new insights into sleep/awake patterns in animals

Research from University of California, Irvine scientists and their colleagues offers new insights into why many animals sleep at night and are active during the day, while others do the reverse. [More]

New study examines effectiveness of pictogram labels on medication-related road traffic crash risk

A new study questions the effectiveness of using pictogram message on the labels of anxiety and sleep medications that interfere with driving - an approach this is currently implemented across France. [More]
Newfound role for PARP proteins could lead to therapeutic opportunities for cancer

Newfound role for PARP proteins could lead to therapeutic opportunities for cancer

Using technology they developed, UT Southwestern Medical Center researchers have identified a previously unknown role of a certain class of proteins: as regulators of gene activity and RNA processing. [More]
Scientists identify potential mechanism that paves way for improved treatment of fungal infections

Scientists identify potential mechanism that paves way for improved treatment of fungal infections

By identifying new compounds that selectively block mitochondrial respiration in pathogenic fungi, Whitehead Institute scientists have identified a potential antifungal mechanism that could enable combination therapy with fluconazole, one of today's most commonly prescribed fungal infection treatments. [More]
Scientists clarify how tumour cells kill specific cells in vascular wall to establish metastases

Scientists clarify how tumour cells kill specific cells in vascular wall to establish metastases

Many cancers only become a mortal danger if they form metastases elsewhere in the body. Such secondary tumours are formed when individual cells break away from the main tumour and travel through the bloodstream to distant areas of the body. [More]
Study finds reduced activity of ACMSD enzyme in people with suicidal behavior

Study finds reduced activity of ACMSD enzyme in people with suicidal behavior

It is known that people who have attempted suicide have ongoing inflammation in their blood and spinal fluid. Now, a collaborative study from research teams in the U.S., Sweden and Australia published in Translational Psychiatry shows that suicidal patients have a reduced activity of an enzyme that regulates inflammation and its byproducts. [More]
UA experts offer advice on choosing right pair of sunglasses

UA experts offer advice on choosing right pair of sunglasses

Experts from the University of Alicante have found that prolonged exposure to the sun increases the chance of developing alterations in the lens by 4%. Choosing the right pair of sunglasses can reduce such complications. [More]
Novel compound holds potential for next-generation prostate cancer treatment

Novel compound holds potential for next-generation prostate cancer treatment

In the search for new ways to attack recurrent prostate cancer, researchers at Duke Health report that a novel compound appears to have a unique way of blocking testosterone from fueling the tumors in mice. [More]
Gasotransmitters in the body could potentially be used to develop new drugs

Gasotransmitters in the body could potentially be used to develop new drugs

Gases once thought of only as environmental pollutants are now known to be produced by the body. They could potentially be used to develop drugs to treat diseases including heart failure and cancer. [More]
Penn researchers develop computer model for designing drug-delivery nanocarriers

Penn researchers develop computer model for designing drug-delivery nanocarriers

A team of University of Pennsylvania researchers has developed a computer model that will aid in the design of nanocarriers, microscopic structures used to guide drugs to their targets in the body. [More]
Combinations of FDA-approved drugs may prevent vision loss linked to retinal degeneration

Combinations of FDA-approved drugs may prevent vision loss linked to retinal degeneration

Combinations of Food and Drug Administration-approved drugs protect against the loss of cells required for vision in a mouse model of blinding retinal diseases. [More]
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