Pharmacology News and Research RSS Feed - Pharmacology News and Research

Pharmacology is the study of how chemical substances interact with living systems. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, interactions, toxicology, therapy, and medical applications and antipathogenic capabilities.
Antibiotic gel shows promise in preventing onset of Lyme borreliosis following tick bite

Antibiotic gel shows promise in preventing onset of Lyme borreliosis following tick bite

An antibiotic gel based on azithromycin, an antibiotic with antibacterial properties, helps to prevent the onset of Lyme borreliosis following a tick bite. [More]
Researchers use CRISPR-based genetic screening to identify three promising HIV treatment targets

Researchers use CRISPR-based genetic screening to identify three promising HIV treatment targets

Investigators from Whitehead Institute, the Ragon Institute of MGH, MIT and Harvard and the Broad Institute of MIT and Harvard have used CRISPR-Cas9 gene-editing technology to identify three promising new targets for treatment of HIV infection. [More]
Novel approach can regenerate dental pulp-like tissues in animal model

Novel approach can regenerate dental pulp-like tissues in animal model

When a tooth is damaged, either by severe decay or trauma, the living tissues that comprise the sensitive inner dental pulp become exposed and vulnerable to harmful bacteria. [More]
New review highlights need to reassess use of biologics for treating rheumatoid arthritis patients

New review highlights need to reassess use of biologics for treating rheumatoid arthritis patients

The use of biologics, which are generally made from human and/or animal materials, has significantly changed the management of rheumatoid arthritis over the last decade, becoming the cornerstone treatment for many patients. [More]
Study suggests revolutionary way to make cancer cells more susceptible to existing chemotherapies

Study suggests revolutionary way to make cancer cells more susceptible to existing chemotherapies

The same signal that drives aggressive growth in a deadly cancer cell type also triggers coping mechanisms that make it "notoriously" hard to kill, according to a study published online December 15 in Cell. When stressed, this cell type - far more than most cancer cells - encases its genetic messages in protein globs called "stress granules" that lessen the effect of chemotherapies. [More]
UT Southwestern researchers develop new imaging method to see proteins in action

UT Southwestern researchers develop new imaging method to see proteins in action

UT Southwestern Medical Center researchers developed a new imaging technique that makes X-ray images of proteins as they move in response to electric field pulses. [More]
Scientists discover new class of host molecules to transport steroids in the body

Scientists discover new class of host molecules to transport steroids in the body

Synthetic hosts are to transport medical substances and hormones into the body and to release them at specific points. [More]
Researchers correct motor symptoms linked to Parkinson's disease in mice

Researchers correct motor symptoms linked to Parkinson's disease in mice

A research group led by University of Helsinki Docent Timo Myöhänen has succeeded in correcting the motor symptoms associated with Parkinson's disease in mice. [More]
Study identifies recurrent genomic alterations in subset of breast cancer

Study identifies recurrent genomic alterations in subset of breast cancer

A genomic analysis study by Rutgers Cancer Institute of New Jersey investigators and other colleagues has identified recurrent genomic alterations in a subset of breast cancer that are typically associated with a form of thyroid cancer and an intestinal birth defect known as Hirschsprung disease. [More]

New review provides insights on rates, predictors of relapse after surgery in Crohn's disease patients

Some patients with Crohn's disease, a chronic inflammatory disease that affects the lining of the digestive tract, require surgery to remove part or all of the large intestine; however, surgery does not cure the condition and many patients relapse after surgery. [More]
Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following publication of research findings today in the journal Science Translational Medicine. [More]
Cold Spring Harbor Laboratory Press publishes new book on key aspects of ciliary biology

Cold Spring Harbor Laboratory Press publishes new book on key aspects of ciliary biology

Nearly every cell in the human body has one or more protrusive structures called cilia or flagella. [More]
Biochemists uncover how potential diabetes drugs interact with LRH-1 protein

Biochemists uncover how potential diabetes drugs interact with LRH-1 protein

Imagine a key that opens a pin tumbler lock. A very similar key can also fit into the lock, but upside down in comparison to the first key. [More]
UMass researchers develop new class of photodynamic molecules for treating deep-tissue tumors

UMass researchers develop new class of photodynamic molecules for treating deep-tissue tumors

UMass Medical School scientist Gang Han, PhD, and his team have designed a new class of molecules used in photodynamic therapy that are able to direct lamp light deep into tissue to kill cancer tumors. [More]
Research unlocks potential new therapies for inflammatory diseases

Research unlocks potential new therapies for inflammatory diseases

Macrophages are frontline cells in our immune system. They detect microbial invaders and also tissue injury and then mount an appropriate response needed to clear the infection and repair the damaged tissue. [More]
Special article outlines recommended strategies to prevent Zika from blood transfusion

Special article outlines recommended strategies to prevent Zika from blood transfusion

As the Zika epidemic spreads to the United States, the potential for contracting the disease via blood transfusion has emerged as a serious concern. [More]
Applying quantitative microscopy to live cells

Applying quantitative microscopy to live cells

Microscopy's got a long history. It was developed about 350 years ago for scientists to visualize things they could discern, but not describe. The two pioneers of microscopy were Antoine van Leeuwenhoek, who developed the first microscope and soon after the renowned scientist, Robert Hooke. [More]
UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Previous studies identified the Hippo pathway kinases LATS1/2 as a tumor suppressor, but new research led by University of California San Diego School of Medicine scientists reveals a surprising role for these enzymes in subduing cancer immunity. The findings, published in Cell on December 1, could have a clinical role in improving efficiency of immunotherapy drugs. [More]
New mouse model provides key information for understanding cortical circuit development

New mouse model provides key information for understanding cortical circuit development

A day by day log of cortical electric activity in the mouse visual cortex was published in the Journal of Neuroscience by George Washington University researcher Matthew Colonnese, Ph.D. [More]
Researchers develop virtual liver model to better understand metabolism of non-prescription painkiller

Researchers develop virtual liver model to better understand metabolism of non-prescription painkiller

Researchers at Indiana University's Biocomplexity Institute have developed a virtual model of the human liver to better understand how the organ metabolizes acetaminophen, a common non-prescription painkiller and fever-reducer used in over-the-counter drugs such as Tylenol. [More]
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