Physiology News and Research

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Human physiology is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems. Most aspects of human physiology are closely homologous to corresponding aspects of animal physiology, and animal experimentation has provided much of the foundation of physiological knowledge. Anatomy and physiology are closely related fields of study: anatomy, the study of form, and physiology, the study of function, are intrinsically tied and are studied in tandem as part of a medical curriculum.

HemoShear announces milestone in development of predictive drug safety systems

HemoShear, LLC, a leading developer of human-relevant systems for drug development and discovery, today announced an important milestone in the development of systems that predict safety of new drugs and chemicals.

19 Jul 2013

Discovery provides evidence that genetic defect responsible for Down syndrome can be suppressed

Scientists at the University of Massachusetts Medical School are the first to establish that a naturally occurring X chromosome "off switch" can be rerouted to neutralize the extra chromosome responsible for trisomy 21, also known as Down syndrome, a genetic disorder characterized by cognitive impairment.

18 Jul 2013

Both milky spots and fat cells in omentum promote ovarian cancer metastases

Cancer researchers have wondered why ovarian cancer cells are so attracted to the abdominal cavity, especially the omentum, with the hope that such an understanding could lead to better disease management or even prevention.

18 Jul 2013

Children exposed to AEDs in womb at risk of early development issues: Study

Children whose mothers took antiepileptic drugs while pregnant are at increased risk of early development issues, according to a new study published in Epilepsia, a journal published by Wiley on behalf of the International League Against Epilepsy.

18 Jul 2013

Long-term cannabis use, dopamine and motivation: an interview with Dr Michael Bloomfield, Department of Medicine at Imperial

We classified ‘long-term’ cannabis use as being regular, at least weekly, cannabis use for over 12 months. This is the period of time that’s used in the DSM-IV psychiatric diagnostic manual to classify substance use disorders. In our study the average duration of at least weekly use was just over four and a half years.

17 Jul 2013

Research couple receives 2013 Khalid Iqbal Lifetime Achievement Award for Alzheimer's study

The research couple receives the "2013 Khalid Iqbal Lifetime Achievement Award" for its role as pioneers in investigating the role of tau in Alzheimer's disease. The award ceremony was held yesterday (10:45 am US EST) within the framework of the "Alzheimer's Association International Conference (AAIC 2013)" in Boston (USA).

17 Jul 2013

Standardized vascular health checks may improve health and cost-effectiveness outcomes

Archimedes Inc., a healthcare modeling company, today announced the results of a two-year long collaboration with Novo Nordisk A/S, a world leader in diabetes care, which evaluated the effects of standardized vascular health checks on expected health outcomes.

17 Jul 2013

Drug to treat multiple sclerosis may also hold promise for treating cardiac hypertrophy

A drug already approved to treat multiple sclerosis may also hold promise for treating cardiac hypertrophy, or thickening of the cardiac muscle--a disorder that often leads to heart failure, researchers at the University of Illinois at Chicago College of Medicine report.

17 Jul 2013

Study explores mechanisms of chemotherapy-induced neurological side effects

Chemotherapy is one of the primary treatments for cancer. However, one of the most disturbing findings of recent studies of cancer survivors is the apparent prevalence of chemotherapy-associated adverse neurological effects, including vascular complications, seizures, mood disorders, cognitive dysfunctions, and peripheral neuropathies.

16 Jul 2013

Researchers uncover role of IKACh in pacemaker activity and heart rate regulation

Researchers have uncovered a previously unknown role for the acetylcholine-activated inward-rectifying potassium current (IKACh) in cardiac pacemaker activity and heart rate regulation, according to a study in The Journal of General Physiology.

16 Jul 2013

Proteins involved in immunity produce cancer-causing DNA mutations, study finds

A set of proteins involved in the body's natural defenses produces a large number of mutations in human DNA, according to a study led by researchers at the National Institutes of Health. The findings suggest that these naturally produced mutations are just as powerful as known cancer-causing agents in producing tumors.

15 Jul 2013

Coffee and appetite: an interview with Matt Schubert and Associate Professor Ben Desbrow, Griffith University

We wanted to do something a bit different than the “typical” work on caffeine and exercise, and I have considerable interest in appetite regulation, so we built up from there.

15 Jul 2013

Urocortin molecule protects cells from osteoarthritis, say researchers

UK scientists have found a naturally occurring molecule in the body which may have important consequences for treating osteoarthritis. Researchers from The University of Manchester and the University of Westminster have found that the molecule, known as Urocortin, protects cells in the joints from being destroyed.

From The University of Manchester 12 Jul 2013

Seven scientists to receive Annual Klerman and Freedman Prizes from Brain & Behavior Research Foundation

Seven young scientists will be recognized by the Brain & Behavior Research Foundation at its presentation of the Annual Klerman and Freedman Prizes on Friday July 26, 2013 at Le Parker Meriden Hotel, New York, NY.

12 Jul 2013

3D-printed airway splint saves life of infant born with severe tracheobronchomalacia

Half a millennium after Johannes Gutenberg printed the bible, researchers printed a 3D splint that saved the life of an infant born with severe tracheobronchomalacia, a birth defect that causes the airway to collapse.

12 Jul 2013

Alnylam releases positive top-line data from ALN-TTRsc Phase I trial for TTR-mediated amyloidosis

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today positive top-line results from its ongoing Phase I trial of ALN-TTRsc, a subcutaneously administered RNAi therapeutic targeting the transthyretin gene for the treatment of TTR-mediated amyloidosis.

12 Jul 2013

Seven named recipients of GSA poster awards at 19th International C. elegans Meeting

Six graduate students and one undergraduate were named as recipients of Genetics Society of America poster awards at the 19th International C. elegans Meeting, held June 26 on the campus of the University of California, Los Angeles.

12 Jul 2013

Research reveals link between elevated BMI and increased risk of gallstone in women

New research reveals a causal association between elevated body mass index (BMI) and increased risk of gallstone disease. Results published in Hepatology, a journal of the American Association for the Study of Liver Diseases, show women are at greater risk of developing gallstones.

12 Jul 2013

Acetaminophen overdose survivors have lower overall health following acute liver failure

Spontaneous survivors of acetaminophen overdose have significantly lower overall health compared to survivors or transplant recipients following acute liver failure caused by non-drug induced liver injury according to a new study published online in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

10 Jul 2013

Lifestyle modification programs may reduce risk of heart attack in people with coronary heart disease

Lifestyle modification programs that addressed at least two health behaviors lowered the risk of a fatal heart attack or stroke in people with coronary heart disease, finds a new systematic review in the American Journal of Preventive Medicine.

10 Jul 2013

Physiology News and Research

HemoShear announces milestone in development of predictive drug safety systems

Discovery provides evidence that genetic defect responsible for Down syndrome can be suppressed

Both milky spots and fat cells in omentum promote ovarian cancer metastases

Children exposed to AEDs in womb at risk of early development issues: Study

Long-term cannabis use, dopamine and motivation: an interview with Dr Michael Bloomfield, Department of Medicine at Imperial

Research couple receives 2013 Khalid Iqbal Lifetime Achievement Award for Alzheimer's study

Standardized vascular health checks may improve health and cost-effectiveness outcomes

Drug to treat multiple sclerosis may also hold promise for treating cardiac hypertrophy

Study explores mechanisms of chemotherapy-induced neurological side effects

Researchers uncover role of IKACh in pacemaker activity and heart rate regulation

Proteins involved in immunity produce cancer-causing DNA mutations, study finds

Coffee and appetite: an interview with Matt Schubert and Associate Professor Ben Desbrow, Griffith University

Urocortin molecule protects cells from osteoarthritis, say researchers

Seven scientists to receive Annual Klerman and Freedman Prizes from Brain & Behavior Research Foundation

3D-printed airway splint saves life of infant born with severe tracheobronchomalacia

Alnylam releases positive top-line data from ALN-TTRsc Phase I trial for TTR-mediated amyloidosis

Seven named recipients of GSA poster awards at 19th International C. elegans Meeting

Research reveals link between elevated BMI and increased risk of gallstone in women

Acetaminophen overdose survivors have lower overall health following acute liver failure

Lifestyle modification programs may reduce risk of heart attack in people with coronary heart disease

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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