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New drug combination could reduce malaria infection risk in pregnant women living with HIV

Researchers have tested a new combination of medications that could thwart resistance to common malaria drugs, significantly reducing the infection risk in pregnant women living with HIV.

24 Jan 2024

New study offers hope for reducing malaria in pregnant women living with HIV

In women living with HIV, preventive treatment with DHA-PPQ is a safe and effective strategy to prevent malaria during pregnancy, according to the final results of MAMAH, a clinical trial funded by the European & Developing Countries Clinical Trials Partnership (EDCTP) and coordinated by the Barcelona Institute for Global Health (ISGlobal), an institution supported by "la Caixa" Foundation.

12 Jan 2024

Purdue researcher receives $1.38 million to fight against drug-resistant malaria in developing countries

A Purdue researcher is taking a giant leap forward in the fight against drug-resistant strains of malaria in developing countries.

15 Sep 2023

Microscopic and submicroscopic malaria in pregnancy: a systematic review and meta-analysis investigates prevalence and associated risk factors

Researchers conducted a systematic review to describe the epidemiology of submicroscopic and microscopic malaria infections during pregnancy.

22 Jun 2023

New antimalarial prevents malaria more effectively than current treatments but does not improve birth outcomes

A large LSTM-led trial confirms new antimalarial, dihydroartemisinin-piperaquine, is more effective at preventing malaria than current WHO recommended treatment but does not improve adverse birth outcomes.

10 Mar 2023

Laos malaria outbreak in 2020–21 likely caused by multidrug-resistant strains of P. falciparum

Researchers describe the genetic epidemiology and dynamics of the Plasmodium falciparum responsible for malaria outbreaks in Attapeu Province, Laos.

5 Dec 2022

Meta-analysis informs a change to treatment guidelines for uncomplicated malaria in the first trimester of pregnancy

A new WWARN meta-analysis commissioned by the World Health Organization (WHO) which informed a change to its treatment guidelines has been published in The Lancet.

28 Nov 2022

The effect of Artemisia annua hot water extracts against the SARS-CoV-2 Omicron variant

Researchers assessed the effect of Artemisia annua hot water extracts against the SARS-CoV-2 Omicron variant.

28 Jul 2022

Researchers evaluate artemisinin for COVID-19 management

Researchers assessed the effectiveness of artemisinin-based antimalarials in the management of COVID-19.

16 Jun 2022

Do Artemisia annua L. compounds have SARS-CoV-2 antiviral potential?

Caused by SARS-CoV-2, the ongoing COVID-19 pandemic has led to over 121.2 million cases and over 2.6 million deaths worldwide. An interesting new study examines the potential antiviral activity of compounds present in the plant Artemisia annua L.

18 Mar 2021

Triple therapies effective and safe in malaria

A new study describing the outcome of a clinical trial of two malaria treatment protocols involving the use of triple therapies based on artemisinin reports their high efficacy and low adverse effects.

12 Mar 2020

Researchers use single cell genome sequencing to study malaria transmission

New technology employing single cell genome sequencing of the parasite that causes malaria has yielded some surprising results and helps pave the way for possible new intervention strategies for this deadly infectious disease, according to Texas Biomedical Research Institute Assistant Professor Ian Cheeseman, Ph.D. Dr. Cheeseman was Principal Investigator of a three-year study published in the January 2020 edition of Cell Host & Microbe, a high-impact peer-reviewed publication.

8 Jan 2020

Artemisinins are still strongest weapon against malaria, say experts

The powerful medicines known as artemisinins have plenty of mileage in them in the global fight against malaria, and concern about partial resistance has been overstated.

26 Apr 2019

Researchers create biocompatible gels using caffeine as catalyst

Caffeine is well-known for its ability to help people stay alert, but a team of researchers at MIT and Brigham and Women's Hospital has now come up with a novel use for this chemical stimulant -- catalyzing the formation of polymer materials.

13 Apr 2018

LSTM researchers show potential of novel antiparasitic drug to combat malaria

Researchers from the Liverpool School of Tropical Medicine have shown the large potential impact of a completely new type of antimalarial drug that kills mosquitoes, as opposed to existing drugs that target the parasite, to reduce the spread of malaria.

27 Mar 2018

Researchers test new anti-malaria medication

An international research team has conducted successful phase II clinical tests of a new anti-malaria medication. The treatment led to a cure in 83 cases.

19 Jan 2018

“Super malaria” resistant to standard medications in South East Asia

The spread of a single multidrug resistant malaria parasite strain in Vietnam is cause for alarm say researchers.

25 Sep 2017

Monell Center receives Gates Foundation grant to support innovative global health research project

The Monell Center announced today that it has received a $345,000 grant from the Bill & Melinda Gates Foundation. The grant supports an innovative global health research project titled, "Developing Novel Pediatric Formulation Technologies for Global Health: Human Taste Assays."

1 Dec 2016

Study compares different strategies to prevent malaria among pregnant women in sub Saharan Africa

A novel strategy to screen pregnant women for malaria with rapid diagnostic tests and treat the test-positive women with effective antimalarials does not lower the risk of adverse pregnancy outcomes compared with treating all pregnant women with the malaria preventive sulfadoxine-pyrimethamine (SP) in sub-Saharan Africa, according to an open label randomized trial published this week in PLOS Medicine by Feiko ter Kuile, of the Liverpool School of Tropical Medicine, and colleagues.

19 Sep 2016

Study assesses acceptability of alternative drug to prevent malaria among pregnant women in Kenya

Researchers at LSTM, working with colleagues at the Centres for Disease Control and Prevention USA, the Kenya Medical Research Institute, and from the London School of Hygiene and Tropical Medicine, have completed a study to assess the acceptability among pregnant women and health providers in Kenya of a new drug as an alternative to the standard drug used to prevent malaria in pregnancy.

21 Mar 2016