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Study links low- and high-birthweight babies to increased cardiovascular disease risk

Study links low- and high-birthweight babies to increased cardiovascular disease risk

For reasons that remain unclear at least in the smaller babies, both birthweight extremes appear to increase the likelihood of early development of dangerous fat around major organs in the abdomen that significantly increases these risks, said Dr. Brian Stansfield, neonatologist at the Children's Hospital of Georgia and the Medical College of Georgia at Augusta University. [More]
Bioprinted 3-D placenta model could help better understand preeclampsia

Bioprinted 3-D placenta model could help better understand preeclampsia

Preeclampsia is a pregnancy complication involving the placenta that can be serious -- even fatal -- for the mother or fetus. The only effective treatment option is premature delivery. [More]
Pluristem completes enrollment in Phase II intermittent claudication trial

Pluristem completes enrollment in Phase II intermittent claudication trial

Pluristem Therapeutics Inc., a leading developer of placenta-based cell therapy products, today announced it has completed the planned enrollment of 150 patients in a global Phase II trial of its PLacental eXpanded (PLX)-PAD cells for the treatment of intermittent claudication (IC), a peripheral artery disease (PAD). The double blind, randomized, placebo controlled trial enrolled 50 patients since October 2015 in the U.S., Germany, Israel, and South Korea. [More]
Mouse models of Zika virus infection in pregnancy provide basis to develop vaccines, treatments

Mouse models of Zika virus infection in pregnancy provide basis to develop vaccines, treatments

Two mouse models of Zika virus infection in pregnancy have been developed by a team of researchers at Washington University School of Medicine in St. Louis. In them, the virus migrated from the pregnant mouse's bloodstream into the placenta, where it multiplied, then spread into the fetal circulation and infected the brains of the developing pups. [More]
Brazilian strain of Zika virus can cause severe birth defects

Brazilian strain of Zika virus can cause severe birth defects

Researchers at University of California San Diego School of Medicine, with colleagues in Brazil and Senegal, have described the first "direct experimental proof" that the Brazilian strain of Zika virus can actually cause severe birth defects. The findings are published in the May 11 online issue of Nature. [More]
New NICE guidance recommends use of Roche Diagnostics’ new pre-eclampsia test

New NICE guidance recommends use of Roche Diagnostics’ new pre-eclampsia test

Obstetricians and midwives are today welcoming the publication of new NICE guidance recommending the use of a new test from Roche Diagnostics that can rule-out the development of the life threatening condition, pre-eclampsia, within one week in pregnant women. [More]
lncRNA in placenta may help protect unborn baby from invading pathogens

lncRNA in placenta may help protect unborn baby from invading pathogens

The human placenta is an organ unlike any other. During the course of nine months it is formed by the embryo, sustains life and then is shed. [More]
Researchers find way to selectively deliver drugs to placenta without harming fetus

Researchers find way to selectively deliver drugs to placenta without harming fetus

Nearly 10 percent of babies born in the United States are born premature, according to the March of Dimes. The underlying cause of many complications during pregnancy is often a poorly functioning placenta, the organ that nourishes and maintains the fetus. [More]
High-fructose diet during pregnancy may affect fetal growth

High-fructose diet during pregnancy may affect fetal growth

Consuming a high-fructose diet during pregnancy may cause defects in the placenta and restrict fetal growth, potentially increasing a baby's risk for metabolic health problems later in life, according to research in mice and people by a team at Washington University School of Medicine in St. Louis. [More]
Study finds link between placenta and offspring bone

Study finds link between placenta and offspring bone

Researchers at the Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, studied 518 children in the Avon Longitudinal Study of Parents and Children (ALSPAC) who underwent bone scans at nine, 15 and 17 years old. Measurements such as thickness, volume and weight, were also taken from the mothers' placenta. [More]
Maternal exposure to air pollution increases risk of long-term health problems in children

Maternal exposure to air pollution increases risk of long-term health problems in children

Even small amounts of air pollution appear to raise the risk of a condition in pregnant women linked to premature births and lifelong neurological and respiratory disorders in their children, new Johns Hopkins Bloomberg School of Public Health research suggests. [More]
Pluristem granted two key cell therapy patents in Japan

Pluristem granted two key cell therapy patents in Japan

Pluristem Therapeutics Inc. (PSTI), a leading developer of placenta-based cell therapy products, has announced that the Japan Patent Office has granted the Company two key patents addressing... [More]
Study links effects of prenatal alcohol and drug exposure with placental development

Study links effects of prenatal alcohol and drug exposure with placental development

In the United States, prenatal alcohol exposure (PAE) is the most common preventable cause of developmental delay. Animal studies have shown some of the adverse effects of PAE on placental development, but few studies have examined these effects in humans. This is the first study to examine the effects of prenatal exposure to methamphetamine, marijuana, and cigarette smoking on human placental development. [More]
Johns Hopkins expert offers tips on Zika virus relating to pregnancy, sexual transmission

Johns Hopkins expert offers tips on Zika virus relating to pregnancy, sexual transmission

No treatment or vaccine currently exists for Zika virus. For most people who contract the virus, the illness will be mild and pass on its own in about one week. [More]
Zika threat to Olympics attendees? An interview with Prof. Eskild Petersen

Zika threat to Olympics attendees? An interview with Prof. Eskild Petersen

The risk in terms of the Olympics, especially for travelling populations remains low – with the notable exception of pregnant women. [More]
Annual economic cost of U.S. premature births linked to air pollution reaches $4.33 billion

Annual economic cost of U.S. premature births linked to air pollution reaches $4.33 billion

The annual economic cost of the nearly 16,000 premature births linked to air pollution in the United States has reached $4.33 billion, according to a report by scientists at NYU Langone Medical Center. [More]
Embryos with abnormalities in initial stages of pregnancy may grow into healthy babies

Embryos with abnormalities in initial stages of pregnancy may grow into healthy babies

Abnormal cells in the early embryo are not necessarily a sign that a baby will be born with a birth defect such as Down's syndrome, suggests new research carried out in mice at the University of Cambridge. In a study published today in the journal Nature Communications, scientists show that abnormal cells are eliminated and replaced by healthy cells, repairing - and in many cases completely fixing - the embryo. [More]
Study: Cox2 inhibition improves outcomes in preeclampsia-like mouse model

Study: Cox2 inhibition improves outcomes in preeclampsia-like mouse model

Preeclampsia is characterized by elevated blood pressure in the second half of pregnancy and impaired blood flow to the placenta, which increases the risk of premature birth and pregnancy complications. [More]
Mothers give offspring a head start in life

Mothers give offspring a head start in life

Thank your mothers: A research collaboration between UC Santa Barbara and L'École Normale Supérieure in Paris has proven that deterministic maternal effects can give offspring a better start on life. [More]
Maternal Immunations app aims to guide, remind pregnant women about vaccines

Maternal Immunations app aims to guide, remind pregnant women about vaccines

A new app to guide and remind pregnant women about vaccines recommended during pregnancy has been launched by researchers [More]
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