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Pneumonia is a leading cause of death and hospitalization, costing health care systems billions of dollars and an estimated 600,000 adult deaths worldwide each year. Pneumococcal disease is caused by the bacterium Streptococcus pneumoniae and the term describes a group of illnesses, including invasive infections, such as bacteremia/sepsis and meningitis, as well as pneumonia and upper respiratory tract infections. Although all age groups may be affected, the highest rate of pneumococcal disease occurs in young children and older adults. In addition, persons suffering from a wide range of chronic conditions (eg, diabetes, cardiovascular disease) and immune deficiencies are at increased risk.
LSTM-led researchers publish findings from lung health study in international respiratory journal

LSTM-led researchers publish findings from lung health study in international respiratory journal

A team of investigators led from LSTM has published findings from a lung health study to determine the prevalence of lung disease among adults in Malawi, in the leading international respiratory journal, the American Journal of Respiratory and Critical Care Medicine. [More]
Increased breastfeeding could save over 800000 children’s lives annually

Increased breastfeeding could save over 800000 children’s lives annually

Just 1 in 5 children in high-income countries are breastfed to 12 months, whilst only 1 in 3 children in low and middle-income countries are exclusively breastfed for the first 6 months. [More]
Three Case Western faculty members receive funding to develop new diagnostic technologies

Three Case Western faculty members receive funding to develop new diagnostic technologies

Three Case Western Reserve University faculty members have received funding to further develop emerging technologies aimed at malaria, cystic fibrosis, and sickle cell anemia. [More]
New breakthrough drug shows promise to fight antibiotic-resistant infections

New breakthrough drug shows promise to fight antibiotic-resistant infections

A New York pharmaceutical company, TGV-Laboratories, has developed a groundbreaking drug that shows promise in treating a wide variety of antibiotic-resistant fungal and bacterial infections. [More]
CosmosID announces $6M in Series B funding round

CosmosID announces $6M in Series B funding round

CosmosID, the leading genomic big data company focused on microbiome research, outbreak investigations, and infectious disease diagnostics, using next-generation DNA sequencing, announced $6M in Series B funding. [More]
UNICEF launches US $2.8 billion appeal to meet the needs of children in crisis

UNICEF launches US $2.8 billion appeal to meet the needs of children in crisis

In the Pacific Islands, many children don’t have enough safe water to drink and their education has been interrupted as result of the severe, ongoing El Niño. [More]
New case of MERS CoV confirmed in Thailand, other states in WHO South-East Asia Region cautioned to remain vigilant

New case of MERS CoV confirmed in Thailand, other states in WHO South-East Asia Region cautioned to remain vigilant

Thailand today confirmed Middle East respiratory syndrome coronavirus disease in a traveler, the second such case in the country in the last seven months, as WHO cautioned other member states in its South-East Asia Region against the continuing risks and the need to remain vigilant. [More]
E-cigarettes suppress immune defenses, alter inflammation and boost bacterial virulence

E-cigarettes suppress immune defenses, alter inflammation and boost bacterial virulence

Researchers at the University of California, San Diego School of Medicine and Veterans Affairs San Diego Healthcare System report data suggesting that e-cigarettes are toxic to human airway cells, suppress immune defenses and alter inflammation, while at the same time boosting bacterial virulence. [More]
Building Health Check launches IAQ Screening Kit for E. coli bacteria

Building Health Check launches IAQ Screening Kit for E. coli bacteria

Following a number of recent outbreaks of E. coli, or Escherichia coli, bacteria at grocers and restaurants across the country, Building Health Check, LLC, has released an Indoor Air Quality (IAQ) Screening Kit for the E. coli bacteria. [More]
Carbapenem-resistant Enterobacteriaceae: an interview with Dr. Michael Dudley

Carbapenem-resistant Enterobacteriaceae: an interview with Dr. Michael Dudley

Enterobacteriaceae refer to the family of bacteria such as E. coli and Klebsiella that are bacterial pathogens most frequently associated with hospital-acquired infections [More]
UC San Diego researchers develop rapid susceptibility test for Staphylococcus aureus

UC San Diego researchers develop rapid susceptibility test for Staphylococcus aureus

A team of biologists and biomedical researchers at UC San Diego has developed a new method to determine if bacteria are susceptible to antibiotics within a few hours, an advance that could slow the appearance of drug resistance and allow doctors to more rapidly identify the appropriate treatment for patients with life threatening bacterial infections. [More]
Positive bosutinib response for elderly blast phase CML patient

Positive bosutinib response for elderly blast phase CML patient

A case study suggests that the third-generation tyrosine kinase inhibitor bosutinib may be considered as induction therapy for blast phase chronic myeloid leukaemia in older patients. [More]
New interprofessional program aims to provide primary care and dental services to older adults

New interprofessional program aims to provide primary care and dental services to older adults

Primary care within a dental practice? It's an interdisciplinary idea that has teeth: Your mouth, noted the U.S. surgeon general in the Oral Health in America report, provides a window into your overall health. Now, a research team led by Maria Dolce, an associate professor in the School of Nursing at Northeastern, will make that idea a reality. [More]
Adding naturally-occurring protein to flu vaccine may offer protection to babies

Adding naturally-occurring protein to flu vaccine may offer protection to babies

According to the World Health Organization, influenza causes serious illness among millions of people each year, resulting in 250,000 to 500,000 deaths. Those most at risk include infants younger than six months, because they cannot be vaccinated against the disease. [More]
Common mortality causes prevail in epilepsy patients

Common mortality causes prevail in epilepsy patients

A prospective, community-based study confirms that patients with epilepsy usually die of the same causes as other people. [More]
Specialized oral nutrition supplement associated with 50% lower death rate in older patients

Specialized oral nutrition supplement associated with 50% lower death rate in older patients

Results from a new clinical trial show that a specialized oral nutrition supplement was associated with a 50 percent lower death rate in older malnourished patients with a heart or lung disease 90 days following hospitalization. [More]
Screening smokers with community-acquired pneumonia could facilitate early diagnosis of lung cancer

Screening smokers with community-acquired pneumonia could facilitate early diagnosis of lung cancer

Lung cancer is the leading cause of cancer mortality in the United States, with a five-year survival rate of just 17 percent. Smoking causes approximately 85 percent of all lung cancer cases, only 15 percent of which are diagnosed at an early stage. Most efforts to obtain early diagnosis have been unsuccessful, largely due to the highly aggressive nature of the disease. [More]
Good bacteria can help inhibit growth of S. pneumoniae

Good bacteria can help inhibit growth of S. pneumoniae

A new study from the Forsyth Institute is helping to shed more light on the important connections among the diverse bacteria in our microbiome. According to research published in mBio, scientists at Forsyth, led by Dr. Katherine P. Lemon, along with their collaborator at Vanderbilt University, have demonstrated that a harmless bacterium found in the nose and on skin may negatively impact the growth of a pathogen that commonly causes middle ear infections in children and pneumonia in children and older adults. [More]
FDA grants Orphan Drug Designation to Ionis Pharmaceuticals' IONIS-HTT Rx for treatment of HD patients

FDA grants Orphan Drug Designation to Ionis Pharmaceuticals' IONIS-HTT Rx for treatment of HD patients

Ionis Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration has granted Orphan Drug Designation to IONIS-HTTRx for the treatment of patients with Huntington's disease (HD). [More]
Forge Therapeutics obtains exclusive license to patent rights related to novel metalloprotein inhibitors

Forge Therapeutics obtains exclusive license to patent rights related to novel metalloprotein inhibitors

Forge Therapeutics, Inc., a biotechnology company developing innovative medicines using a breakthrough drug discovery platform targeting metalloproteins, announced today it has obtained an exclusive license from the University of California San Diego to patent rights related to novel metalloprotein inhibitors discovered in the laboratory of Forge Therapeutics scientific co-founder Professor Seth Cohen, Ph.D. [More]
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