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Pneumonia is a leading cause of death and hospitalization, costing health care systems billions of dollars and an estimated 600,000 adult deaths worldwide each year. Pneumococcal disease is caused by the bacterium Streptococcus pneumoniae and the term describes a group of illnesses, including invasive infections, such as bacteremia/sepsis and meningitis, as well as pneumonia and upper respiratory tract infections. Although all age groups may be affected, the highest rate of pneumococcal disease occurs in young children and older adults. In addition, persons suffering from a wide range of chronic conditions (eg, diabetes, cardiovascular disease) and immune deficiencies are at increased risk.
Structures on surface of pneumococci determine bacteria’s ability to cause meningitis

Structures on surface of pneumococci determine bacteria’s ability to cause meningitis

Structures on the surface of pneumococci determine the ability of these bacteria to enter the brain and cause severe infections, according to a paper published in The Journal of Clinical Investigation by researchers at Karolinska Institutet. [More]
Alcohol intoxication perturbs immune system of aged individuals

Alcohol intoxication perturbs immune system of aged individuals

The immune system in the elderly is dysfunctional and infections are more prevalent, more severe, and harder to defeat. Drinking alcohol has a variety of damaging effects on the immune system and organs - like the gut, liver and lung - which can be worsened by pre-existing conditions as well as consumption of prescription and over-the-counter medications that aged individuals often take. [More]
Researchers find new way for treating GBS infection in neonates

Researchers find new way for treating GBS infection in neonates

Researchers have discovered how the bacteria Group B streptococcus (GBS) avoids detection by the immune system during pregnancy. [More]
Anthrax capsule vaccine offers protection from deadly anthrax infection in monkeys

Anthrax capsule vaccine offers protection from deadly anthrax infection in monkeys

Vaccination with the anthrax capsule--a naturally occurring component of the bacterium that causes the disease--completely protected monkeys from lethal anthrax infection, according to a study published online this week in the journal VACCINE. [More]
Study shows increase in costs of hospitalization for people with private insurance

Study shows increase in costs of hospitalization for people with private insurance

Even if you have what you might think of as good health insurance, your next hospital stay could cost you more than $1,000 out of your own pocket. [More]
FDA approves novel stomach-draining device to treat obesity

FDA approves novel stomach-draining device to treat obesity

The U.S. Food and Drug Administration today approved a new obesity treatment device that uses a surgically-placed tube to drain a portion of the stomach contents after every meal. [More]
How can we defeat drug resistance? An interview with Dr Grania Brigden

How can we defeat drug resistance? An interview with Dr Grania Brigden

The O’Neill report is a wide ranging report recognising anti-microbial resistance (AMR) as a global problem with major public health and economic significance. [More]
Tiny molecular scaffolding could be key to fight against antibiotic resistance

Tiny molecular scaffolding could be key to fight against antibiotic resistance

Tiny molecular scaffolding that joins molecules together could be the key to our battle against antibiotic resistance. Research published in Bioorganic & Medicinal Chemistry Letters shows that carbon nanodot scaffolding assembled with small molecules called polyamines can kill some dangerous drug-resistant bacteria, including Acinetobacter baumanii and Klebsiella pneumonia. [More]
New experimental antibiotic can help combat MRSA infections

New experimental antibiotic can help combat MRSA infections

A new experimental antibiotic developed by a team of scientists at Rutgers University successfully treats the deadly MRSA infection and restores the efficacy of a commonly prescribed antibiotic that has become ineffective against MRSA. [More]
New immunization approach may one day wipe out pneumonia, meningitis

New immunization approach may one day wipe out pneumonia, meningitis

A new vaccine allows pneumonia-causing bacteria to colonize inside the body, springing into action only if the bacteria pose a threat. [More]
Global increase in sale of baby formula raises concerns about health of infants, mothers

Global increase in sale of baby formula raises concerns about health of infants, mothers

A new study from The Australian National University has found a global boom in the sale of infant and baby formula, especially in China and Southeast Asia, raising concerns about the health of millions of mothers and their babies. [More]
Maternal vaccination against influenza can reduce flu risk in newborns

Maternal vaccination against influenza can reduce flu risk in newborns

Each year, influenza causes between 250,000 and half a million deaths around the world. Pregnant women and young infants have a higher risk of complications related to influenza; these complications can easily lead to death. [More]
Readmission rates after major cancer procedures depend on patient cohort, hospital characteristics

Readmission rates after major cancer procedures depend on patient cohort, hospital characteristics

Readmission rates after complex cancer operations tend to be higher in hospitals that are considered to be vulnerable because they serve as safety nets in their communities or have a high number of Medicaid patients. [More]
Cigarette smoke promotes bacteria colonization, immune invasion

Cigarette smoke promotes bacteria colonization, immune invasion

The mouth is one of the "dirtiest" parts of the body, home to millions of germs. But puffing cigarettes can increase the likelihood that certain bacteria like Porphyromonas gingivalis will not only set up camp but will build a fortified city in the mouth and fight against the immune system. [More]
New data visualization platform identifies shortfalls in vaccine introduction and coverage

New data visualization platform identifies shortfalls in vaccine introduction and coverage

As the 69th World Health Assembly discusses progress on the Global Vaccine Action Plan, a new data visualization platform--from the International Vaccine Access Center at the Johns Hopkins Bloomberg School of Public Health--provides stark numbers on where shortfalls exist in vaccine introduction and coverage. [More]
Care-related infection measurements not followed up in hospitals, study finds

Care-related infection measurements not followed up in hospitals, study finds

Suffering from an infection during a hospital stay is a common care-related injury. To prevent spreading and to work preventively, all hospitals measure the occurrence of care-related infections. [More]
Heart failure patients who receive influenza vaccine less likely to develop dementia

Heart failure patients who receive influenza vaccine less likely to develop dementia

Influenza vaccination is associated with a lower risk of dementia in patients with heart failure, according to a study in more than 20 000 patients presented today at Heart Failure 2016 and the 3rd World Congress on Acute Heart Failure by Dr Ju-Chi Liu, director of the Division of Cardiovascular Medicine, Department of Medicine, Taipei Medical University - Shuang Ho Hospital, in New Taipei City, Taiwan. [More]
Children treated at stand-alone Level I PTC have better outcomes following motor vehicle accident

Children treated at stand-alone Level I PTC have better outcomes following motor vehicle accident

Children and adolescents injured in motor vehicle accidents have better outcomes when treated at a stand-alone Level I pediatric trauma center (PTC) than at general adult trauma centers (ATC) or adult trauma centers with added Level I pediatric qualifications (ATC+PTC), according to a new study to be published in the Journal of Pediatric Surgery by researchers from Children's Minnesota. [More]
Study finds that ACS NSQIP Surgical Risk Calculator has excellent calibration

Study finds that ACS NSQIP Surgical Risk Calculator has excellent calibration

The American College of Surgeons National Surgical Quality Improvement Program Surgical Risk Calculator accurately estimates the chance of a patient experiencing postoperative complications, and its performance can improve with recalibration of the tool according to research findings appearing online in the Journal of the American College of Surgeons in advance of print publication. [More]
Natural product darwinolide may help combat fatal MRSA infection

Natural product darwinolide may help combat fatal MRSA infection

A serious and sometimes fatal bacterial infection, known as methicillin-resistant Staphylococcus aureus (MRSA), may soon be beatable thanks to the efforts of University of South Florida scientists who have isolated and tested an extract from a sponge found in Antarctica. [More]
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