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Pneumonia is a leading cause of death and hospitalization, costing health care systems billions of dollars and an estimated 600,000 adult deaths worldwide each year. Pneumococcal disease is caused by the bacterium Streptococcus pneumoniae and the term describes a group of illnesses, including invasive infections, such as bacteremia/sepsis and meningitis, as well as pneumonia and upper respiratory tract infections. Although all age groups may be affected, the highest rate of pneumococcal disease occurs in young children and older adults. In addition, persons suffering from a wide range of chronic conditions (eg, diabetes, cardiovascular disease) and immune deficiencies are at increased risk.
Mutations in gene that enables memories, sense of direction can contribute to schizophrenia symptoms

Mutations in gene that enables memories, sense of direction can contribute to schizophrenia symptoms

Mutations in a gene that should enable memories and a sense of direction instead can result in imprecise communication between neurons that contributes to symptoms of schizophrenia, scientists report. [More]
Improving fungal disease diagnostics could help battle against antimicrobial resistance

Improving fungal disease diagnostics could help battle against antimicrobial resistance

Ignorance of fungal disease and lack of diagnostics across the world is causing doctors to unknowingly overprescribe antibiotics a new report warns. [More]
Better fungal disease diagnostics could be critical to fight against antimicrobial resistance

Better fungal disease diagnostics could be critical to fight against antimicrobial resistance

Poor diagnosis worldwide of fungal disease causes doctors to overprescribe antibiotics, increasing harmful resistance to antimicrobial drugs, according to a paper published today in Emerging Infectious Diseases. [More]
Important vaccines that should not be missed by adults, elders and pregnant women

Important vaccines that should not be missed by adults, elders and pregnant women

Vaccines are an important part of routine healthcare for adults, seniors and women who are pregnant. [More]
Vaccine campaign targeting freshers could hold key to reducing spread of meningitis

Vaccine campaign targeting freshers could hold key to reducing spread of meningitis

A campaign targeted at students arriving at university for the first time could hold the key to reducing the spread of meningitis and septicaemia, say researchers at the universities of Nottingham and Leicester. [More]
Researchers finding way to manipulate signals in bacteria to reduce infections

Researchers finding way to manipulate signals in bacteria to reduce infections

The University of Illinois at Chicago College of Pharmacy has received a five-year, $1.25 million federal grant to continue its research into how bacteria that cause streptococcal infections can be manipulated. [More]
S. pneumoniae uses hosts' immune defenses to spread infection, study reveals

S. pneumoniae uses hosts' immune defenses to spread infection, study reveals

The bacteria that cause most cases of pneumonia worldwide secrete a toxin that helps them jump from one body to the next - with help from the hosts' immune defenses. This is the finding of a study led by researchers from NYU Langone Medical Center and published online January 11 in Cell Host & Microbe. [More]
Dutch scientists discover favorable conditions for growth of Legionella bacteria

Dutch scientists discover favorable conditions for growth of Legionella bacteria

The bacteria that cause Legionnaire's disease grow well in warm tap water installations with ample dissolved organic matter--conditions that support the growth of biofilms. The research is published January 6th in Applied and Environmental Microbiology, a journal of the American Society for Microbiology. [More]
New study from Veterans Health Administration finds significant decline in MRSA HAI rates

New study from Veterans Health Administration finds significant decline in MRSA HAI rates

The Department of Veterans Affairs' Veterans Health Administration's campaign to limit healthcare facility-associated infections (HAIs) of methicillin-resistant Staphylococcus aureus (MRSA) continues to make significant progress, according to a study published in the January issue of the American Journal of Infection Control, the official journal of the Association for Professionals in Infection Control and Epidemiology . [More]
Monthly high dose of vitamin D lowers respiratory infections in older adults

Monthly high dose of vitamin D lowers respiratory infections in older adults

In people over the age of 65, acute respiratory infections--such as the common cold, influenza, or pneumonia--can lead to potentially life-threatening complications. [More]
CRCHUM receives NIH grant to study ways to prevent mortality after myocardial infarction

CRCHUM receives NIH grant to study ways to prevent mortality after myocardial infarction

The University of Montreal Hospital Research Centre has been awarded a grant of US$2 million from the National Institutes of Health to pilot the Canadian component of a study to determine the optimal amount of blood to transfuse in anemic patients who have suffered a myocardial infarction. [More]
Financial penalties can reduce hospital readmissions

Financial penalties can reduce hospital readmissions

Hospitals that were financially penalized for too many readmissions were more likely than non-penalized institutions to subsequently reduce readmissions for all conditions, according to a new study by Yale School of Medicine researchers and colleagues in the Journal of the American Medical Association. [More]
Research reveals how microbial context during infectious disease can compromise antibiotic therapy

Research reveals how microbial context during infectious disease can compromise antibiotic therapy

Bacteria that are susceptible to antibiotics can survive when enough resistant cells around them are expressing an antibiotic-deactivating factor. [More]
New comprehensive study lists top personal health expenses in the U.S.

New comprehensive study lists top personal health expenses in the U.S.

Just 20 conditions make up more than half of all spending on health care in the United States, according to a new comprehensive financial analysis that examines spending by diseases and injuries. [More]
ACA financial penalties lead to reductions in hospital readmission rates for common conditions

ACA financial penalties lead to reductions in hospital readmission rates for common conditions

Financial penalties levied under the Affordable Care Act's Hospital Readmissions Reduction Program lead to the poorest performing hospitals to achieve the greatest reductions in readmission rates for common conditions. [More]
Study examines mechanisms for measuring and reporting postoperative infection complications

Study examines mechanisms for measuring and reporting postoperative infection complications

How do medical professionals determine whether or not a patient has experienced a post-operative complication? A team of Mayo Clinic physicians and researchers has published results of a three-year study examining mechanisms for measuring and reporting postoperative infection complications. [More]
Researchers engineer promising live-attenuated RSV vaccine candidate

Researchers engineer promising live-attenuated RSV vaccine candidate

Crafting a vaccine against RSV (respiratory syncytial virus) has been a minefield for 50 years, but scientists believe they have found the right balance. [More]
Texas A&M professor shares tips to protect infants from RSV

Texas A&M professor shares tips to protect infants from RSV

Coughing, sneezing and a runny nose: You might think it is yet another cold, but if your baby is under 2 years old, it could very well be respiratory syncytial virus (RSV). [More]
ANTRUK's new research finds promising leads to combat antibiotic resistance

ANTRUK's new research finds promising leads to combat antibiotic resistance

Antibiotic resistant infections are predicted to lead to 10 million deaths per year globally by 2050 at a cost of up to $100 trillion to the world economy. In the UK, at least 5,000 people per year die from resistant infections. [More]
How can we tackle antimicrobial resistance?

How can we tackle antimicrobial resistance?

Antimicrobial resistance happens when bugs, like bacteria, fungi or viruses, change, or evolve, when they’re exposed to drugs, like antibiotics, antifungals, or antivirals. Bugs that develop antimicrobial resistance are sometimes referred to as ‘superbugs’. [More]
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