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Pneumonia is a leading cause of death and hospitalization, costing health care systems billions of dollars and an estimated 600,000 adult deaths worldwide each year. Pneumococcal disease is caused by the bacterium Streptococcus pneumoniae and the term describes a group of illnesses, including invasive infections, such as bacteremia/sepsis and meningitis, as well as pneumonia and upper respiratory tract infections. Although all age groups may be affected, the highest rate of pneumococcal disease occurs in young children and older adults. In addition, persons suffering from a wide range of chronic conditions (eg, diabetes, cardiovascular disease) and immune deficiencies are at increased risk.
Early identification of heart disease a priority for schizophrenia patients

Early identification of heart disease a priority for schizophrenia patients

Early recognition and treatment of coronary artery disease must become a clinical priority for all adults with schizophrenia, say researchers who studied autopsy data for schizophrenia patients who died suddenly in hospital. [More]
New tool can help doctors identify patients at highest risk for respiratory failure after surgery

New tool can help doctors identify patients at highest risk for respiratory failure after surgery

A new prediction tool can help doctors better identify patients who are at highest risk for respiratory failure after surgery and therefore prevent the often deadly condition, suggest data from a large multi-center study published in the May issue of Anesthesiology. [More]
Pediatrician reviews co-pathogenesis of influenza viruses with bacteria in lung

Pediatrician reviews co-pathogenesis of influenza viruses with bacteria in lung

Le Bonheur Children's Hospital Pediatrician-in-Chief Jon McCullers, MD, was recently invited to submit a review in the April issue of Nature Reviews Microbiology, one of the world's foremost scientific publications. [More]
Study finds ginseng can help prevent, treat influenza and RSV infection

Study finds ginseng can help prevent, treat influenza and RSV infection

Ginseng can help treat and prevent influenza and respiratory syncytial virus (RSV), a respiratory virus that infects the lungs and breathing passages, according to research findings by a scientist in Georgia State University's new Institute for Biomedical Sciences. [More]
Cubist submits ceftolozane/tazobactam NDA for treatment of cUTI and cIAI

Cubist submits ceftolozane/tazobactam NDA for treatment of cUTI and cIAI

Cubist Pharmaceuticals, Inc. today announced that it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration for approval of its investigational antibiotic ceftolozane/tazobactam for the treatment of Complicated Urinary Tract Infections (cUTI) and Complicated Intra-Abdominal Infections (cIAI). [More]
Benzodiazepines may contribute to respiratory problems in people with COPD

Benzodiazepines may contribute to respiratory problems in people with COPD

A group of drugs commonly prescribed for insomnia, anxiety and breathing issues "significantly increase the risk" that older people with chronic obstructive pulmonary disease, or COPD, need to visit a doctor or Emergency Department for respiratory reasons, new research has found. [More]

Study shows how infection worsens damage caused by stroke

Infection is bad news for all of us - but it can be really serious to people who have had a stroke. Evidence is mounting that infection makes things much worse after a stroke. [More]

S. pneumoniae serotypes differ between primary and post-viral disease

Certain capsular serotypes of Streptococcus pneumoniae are particularly likely to cause disease in people who have recently experienced a respiratory viral infection, study findings indicate. [More]
Study examines effect of community on hospital readmission rates

Study examines effect of community on hospital readmission rates

Nearly 60 percent of the variation in hospital readmission rates appears to be associated with where the hospital is located rather than on the hospital's performance, finds a new study in Health Services Research. [More]
Guidance on use of Tamiflu needs to be reviewed in light of most recent evidence

Guidance on use of Tamiflu needs to be reviewed in light of most recent evidence

Tamiflu (the antiviral drug oseltamivir) shortens symptoms of influenza by half a day, but there is no good evidence to support claims that it reduces admissions to hospital or complications of influenza. [More]
Scientists discover promising agents to fight antibiotic-resistant bacteria

Scientists discover promising agents to fight antibiotic-resistant bacteria

In the fight against "superbugs," scientists have discovered a class of agents that can make some of the most notorious strains vulnerable to the same antibiotics that they once handily shrugged off. The report on the promising agents called metallopolymers appears in the Journal of the American Chemical Society. [More]
Researchers demonstrate advantages of HOPE fixation strategy

Researchers demonstrate advantages of HOPE fixation strategy

They discovered that the so-called HOPE method allows tissue samples to be treated such that they do not only meet the requirements of clinical histology, but can still be characterised later on by modern methods of proteomics, a technique analysing all proteins at once. [More]
Expert guidance highlights strategies to prevent catheter-associated urinary tract infections

Expert guidance highlights strategies to prevent catheter-associated urinary tract infections

New expert guidance highlights strategies for implementing and prioritizing efforts to prevent catheter-associated urinary tract infections (CAUTI) in hospitals. [More]
Janssen submits supplemental New Drug Application for IMBRUVICA to the U.S. FDA

Janssen submits supplemental New Drug Application for IMBRUVICA to the U.S. FDA

Janssen Research & Development, LLC ("Janssen") today announced the submission of a supplemental New Drug Application (sNDA) for IMBRUVICA™ (ibrutinib) to the U.S. Food and Drug Administration (FDA) by its collaboration partner Pharmacyclics, Inc. [More]

Fewer blood transfusions reduce infection rates by nearly 20%

Blood transfusions are among the most common treatments for hospitalized patients nationwide, but doing them less often reduces infection rates by nearly 20 percent, according to a study in the Journal of the American Medical Association co-authored by Neil Blumberg, M.D., professor at the University of Rochester School of Medicine and Dentistry. [More]
S. pneumoniae is commonest cause of paediatric CAP

S. pneumoniae is commonest cause of paediatric CAP

Streptococcus pneumoniae is the predominant cause of community-acquired pneumonia among children in Belgium, with non-vaccine serotypes accounting for the majority of cases, a Belgian study shows. [More]
Clinigen Group announces acquisition of SAVENE oncology support therapy from SpePharm

Clinigen Group announces acquisition of SAVENE oncology support therapy from SpePharm

Clinigen Group plc ('Clinigen' or the 'Group') the specialty global pharmaceutical company today announces the acquisition of SAVENE® (dexrazoxane) from SpePharm AG, a majority owned affiliate of Norgine B.V. The Financial terms of the acquisition are not being disclosed. [More]

Hospital infection rates down, but patients still dying of preventable causes

Hospitals and nursing homes have been trying to cut the facility-acquired infection rates, which has worked better for some conditions than others. [More]

Low dose injections of artificial properdin provides protection against septic diseases in mice

Breakthrough MRC-funded study from University of Leicester shows low dose injections of artificial properdin provides substantial protection against septic diseases in mice [More]
ASU scientist selected as 2014 recipient of Lifetime Achievement Award

ASU scientist selected as 2014 recipient of Lifetime Achievement Award

Roy Curtiss III, a scientist at the Biodesign Institute at Arizona State University, has been selected as the 2014 recipient of the Lifetime Achievement Award from the American Society for Microbiology. [More]