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MIT researchers develop new method to quickly screen cancer-associated genetic mutations

Tumors can carry mutations in hundreds of different genes, and each of those genes may be mutated in different ways -; some mutations simply replace one DNA nucleotide with another, while others insert or delete larger sections of DNA.

12 Mar 2024

Unveiling the molecular mechanism responsible for crossover interference during meiosis

Movies such as 'X-Men,' 'Fantastic Four,' and 'The Guardians,' which showcase vibrant mutant heroes, have captivated global audiences.

7 Mar 2024

Study uncovers a biological role of transmembrane protein TMEM208

A recent study conducted in the lab of Dr. Hugo J. Bellen, distinguished service professor at Baylor College of Medicine and principal investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, has discovered a biological role of a specific transmembrane protein called TMEM208.

23 Feb 2024

Decoding the differences between two vital RNA transport complexes

Genetic expression, often leading to protein synthesis, requires a complex coordination of molecular machinery across several stages.

8 Feb 2024

Unexpected link between pure mathematics and genetics discovered

An interdisciplinary team of mathematicians, engineers, physicists, and medical scientists have uncovered an unexpected link between pure mathematics and genetics, that reveals key insights into the structure of neutral mutations and the evolution of organisms.

8 Aug 2023

New study spotlights effective strategy against COVID-19 variants: the E7 monoclonal antibody

Researchers developed potent monoclonal antibodies from a severe acute respiratory syndrome coronavirus (SARS-CoV) survivor.

1 Aug 2023

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

A recent study reveals that DCAF1 is overexpressed and phosphorylates EZH2 in colon cancer cells.

18 Apr 2023

Study finds minimal impact of SARS-CoV-2 genome variability on current diagnostic molecular systems

The authors of a new study under review at the journal Scientific Reports and currently posted to the Research Square preprint* server proposed a novel analysis pipeline to help identify mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcription-polymerase chain reaction (RT-PCR) primer regions.

29 Mar 2023

One-Pot-LAMP: A promising tool for non-small cell lung cancer diagnosis

Researchers assessed the efficiency of a genetic decoding system for diagnosing non-small cell lung cancer (NSCLC).

16 Mar 2023

Important backup mechanism of human immune cells elucidated

The enzyme TBK1 is an important component of the innate immune system that plays a critical role in the defense against viruses.

10 Mar 2023

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Researchers highlight recent research investigating whether gut microbiota regulates tau pathology and tau-mediated neurodegeneration in an ApoE isoform–dependent manner.

21 Feb 2023

Cryo-electron microscopy captures the first 3D structure of SPOP protein that drives cancer

SPOP is the most mutated protein in prostate cancer and plays a role in endometrial, uterine and other cancers. Despite this importance, how SPOP mutations drive cancer has been incompletely understood.

23 Jan 2023

Researchers report that vectored expression of a high-affinity ACE2 microbody protein establishes a high degree of protection from SARS-CoV-2

Researchers evaluated the use of receptor decoys for SARS-CoV-2 based on soluble forms of ACE2 for immunological prophylaxis and management of COVID-19 through the use of AAV vectors.

16 Jan 2023

Point mutation News and Research

MIT researchers develop new method to quickly screen cancer-associated genetic mutations

Unveiling the molecular mechanism responsible for crossover interference during meiosis

Study uncovers a biological role of transmembrane protein TMEM208

Decoding the differences between two vital RNA transport complexes

Unexpected link between pure mathematics and genetics discovered

New study spotlights effective strategy against COVID-19 variants: the E7 monoclonal antibody

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

Study finds minimal impact of SARS-CoV-2 genome variability on current diagnostic molecular systems

One-Pot-LAMP: A promising tool for non-small cell lung cancer diagnosis

Important backup mechanism of human immune cells elucidated

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Cryo-electron microscopy captures the first 3D structure of SPOP protein that drives cancer

Researchers report that vectored expression of a high-affinity ACE2 microbody protein establishes a high degree of protection from SARS-CoV-2

New insights on the circadian clock of Drosophila melanogaster

MTCH2 acts as a doorway for proteins into the mitochondrial membrane, study reveals

Bivalent recombinant vaccine protects against SARS-CoV-2 and influenza in animal models

Fast and sensitive paper-based nucleic acid assay for SARS-CoV-2

UCI researchers develop novel test that detects specific SARS-CoV-2 variants with 100% accuracy

ADAR1 mutation sets off biochemical pathways that produce an organ-damaging autoimmune response

The impact of the SARS-CoV-2 spike A222V mutation on viral infection

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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