Positron Emission Tomography News and Research

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First COX-2-targeted PET imaging agent for use in animal models of inflammation, cancer

A series of novel imaging agents could make it possible to "see" tumors in their earliest stages, before they turn deadly.

10 Oct 2011

Researchers reveal how motivation facilitates motor functional recovery in stroke, SCI patients

An effective recovery has been observed in stroke patients and those with spinal cord injuries who have strong vitality and motivation to rehabilitate in clinical practice. However, it was not really clear how motivation facilitates functional recovery in brain science.

29 Sep 2011

UCLA's gene-based imaging system can accurately detect metastatic prostate cancers

Researchers at UCLA's Jonsson Comprehensive Cancer Center have developed a way to image the spread of a particularly dangerous form of prostate cancer earlier than conventional imaging in use today, which may allow oncologists to find and treat these metastases more quickly and give patients a better chance at survival.

23 Sep 2011

New GE healthymagination initiative aims to improve cancer innovation and care

GE and leading healthcare and financial partners today launched a new healthymagination initiative aimed at accelerating cancer innovation and improving care for 10 million cancer patients around the world by 2020.

16 Sep 2011

Glucose metabolism inhibition with 2-DG induces cell death in alveolar rhabdomyosarcoma

A study made by IDIBELL researchers shows that glucose metabolism inhibition with 2-deoxyglucose (2-DG) induces cell death in a type of childhood sarcoma: alveolar rhabdomyosarcoma.

15 Sep 2011

Researchers use MRI and PET/CT to assess safety, efficacy of heart drug dalcetrapib

Researchers from Mount Sinai School of Medicine have for the first time used several imaging techniques to prove the efficacy of a promising new treatment for atherosclerosis—the build-up of plaque in artery walls that can lead to a heart attack.

13 Sep 2011

Ohio Third Frontier grants to advance Philips Healthcare Global Advanced Imaging Innovation Center

The Ohio Third Frontier Commission has awarded $2.5 million in research grants to advance the Philips Healthcare Global Advanced Imaging Innovation Center, a collaboration among Case Western Reserve University, University Hospitals (UH) Case Medical Center and Philips Healthcare. The research projects are part of $30 million in funding awarded throughout the State of Ohio this week by the Ohio Third Frontier Commission.

8 Sep 2011

Glioma stem cells can change their metabolic state at will, finds study

The metabolic state of glioma stem cells, which give rise to deadly glioblastomas, is significantly different from that of the brain cancer cells to which they give birth, a factor which helps those stem cells avoid treatment and cause recurrence later.

7 Sep 2011

Positive topline data from 4SC's resminostat Phase II trial on Hodgkin's Lymphoma

4SC AG, a discovery and development company of targeted small molecule drugs for autoimmune diseases and cancer, today announced positive topline data from its Phase II SAPHIRE trial with resminostat, its oral pan HDAC inhibitor, in patients with relapsed/refractory Hodgkin's Lymphoma.

6 Sep 2011

Scientists aim to tackle Hawaii's liver cancer problem with improved detection

Two scientists from the University of Hawaii Cancer Center and The Queen's Medical Center have received a five-year $2.3 million grant from the National Cancer Institute to develop novel methods that can better detect liver cancer through the joint analysis of gene expression and imaging data of the liver.

24 Aug 2011

Study confirms tamoxifen is superior to fulvestrant in blocking estrogen

For the first time, researchers at Seattle Cancer Care Alliance have demonstrated the feasibility of using serial positron emission tomography (PET) scans, using a special estrogen-containing isotope, to confirm the relative effectiveness of estrogen-blocking and estrogen-depleting therapy in patients with metastatic breast cancer.

19 Aug 2011

IMRT produces high response rate in patients with extranodal lymphoma of head and neck: Research

Lymphoma is a cancer that affects organs of the immune system, including the lymph nodes. In a subtype of the disease called extranodal lymphoma, tumors arise in non-lymphoid organs, such as the tongue and tonsils.

16 Aug 2011

Siemens receives Health Canada Medical Device License for Biograph mMR

Siemens Canada Healthcare has received a Health Canada Medical Device License for the Biograph mMR.

4 Aug 2011

Role of molecular imaging in diagnosis and clinical trials

Two new studies published in the August issue of The Journal of Nuclear Medicine (JNM) provide insight into the potential of positron emission tomography (PET) to differentiate between types of dementia and to identify pharmaceuticals to slow the progress of dementia. With proposed National Institute on Aging (NIA) and the Alzheimer's Association guidelines for detecting Alzheimer's-related brain changes expected in September, these articles give a preview of what may be to come.

3 Aug 2011

Mood-related brain protein linked to sadness during cigarette withdrawal

Heavy smokers may experience sadness after quitting because early withdrawal leads to an increase in the mood-related brain protein monoamine oxidase A (MAO-A), a new study by the Centre for Addiction and Mental Health (CAMH) has shown. This finding, which was published in the Archives of General Psychiatry, may also explain why heavy smokers are at high risk for clinical depression.

3 Aug 2011

High methodological quality studies of PET in malignant melanoma patients needed

The relevance of positron emission tomography (PET) alone or in combination with computed tomography (CT) in patients with malignant melanoma cannot be currently assessed due to a lack of meaningful studies. This is the result of a final report published by the German Institute for Quality and Efficiency in Health Care (IQWiG) on 20 July 2011.

21 Jul 2011

Three flutemetamol clinical abstracts to be presented at 2011 Alzheimer's Association ICAD

Recent clinical research data reported that the investigational amyloid imaging agent [18F]Flutemetamol showed highly consistent image interpretation1 and showed comparable in vitro binding to the Pittsburgh Compound-B investigational imaging agent3.

21 Jul 2011

Falling may be an early sign of Alzheimer's

In a new study presented at the Alzheimer's Association's annual International Conference in Paris it was reported that older people whose brain scans showed signs of amyloid plaques - an early indicator of Alzheimer's disease - but who were otherwise healthy, had twice the risk of falls as people without brain amyloid.

20 Jul 2011

Earlier Alzheimer’s disease and dementia diagnosis: New guidelines

It has been the tradition to confirm the presence of Alzheimer's disease during autopsy. However new guidelines proposed on Sunday by the U.S. National Institute on Aging and the Alzheimer's Association seek to distinguish between memory changes or dementia diagnosed by doctors when people are alive, and the changes pathologists can see in an autopsy.

18 Jul 2011

Cardinal Health opens The Center for the Advancement of Molecular Imaging in Phoenix

Today in Phoenix, Cardinal Health opened The Center for the Advancement of Molecular Imaging – a new, first-of-its-kind collaboration laboratory that will expedite the development of nuclear imaging agents that treat complex diseases like cancer, heart disease and neurological disorders.