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Cannabis shows promise in easing endometriosis pain, new research suggests

The Journal of Clinical Medicine review explores cannabis as a self-management strategy for endometriosis pain, revealing its potential to reduce gut inflammation and improve gut permeability, thereby alleviating bloating and suppressing pain through interactions with the endocannabinoid system and gut microbiota.

14 Nov 2023

Study finds lack of high certainty evidence on the efficacy and safety of analgesics for low back pain

Despite nearly 60 years of research, there is still a lack of high certainty evidence on the effectiveness and safety of commonly used painkillers (analgesics) for short bouts of low back pain, finds an analysis of the evidence published by The BMJ.

23 Mar 2023

Novel multimodal analgesia protocol following total knee arthroplasty provides pain relief without opioids

A study led by Vinod Dasa, MD, Professor of Orthopaedics at LSU Health New Orleans School of Medicine, reports that a novel surgical pain management strategy following total knee arthroplasty (TKA), or total knee replacement, provided pain relief without opioids.

27 Feb 2023

Researchers assess the evidence basis for medications used to treat spine-related pain in older adults

Spine-related pain is increasingly common in older adults. While medications play an important role in pain management, their use has limitations in geriatric patients due to reduced liver and kidney function, comorbid medical problems and polypharmacy (the simultaneous use of multiple drugs to treat medical conditions).

28 Jun 2022

Existing drug may reduce damage after spinal cord injury, research shows

Scientists from the University of Birmingham have shown an existing drug may reduce damage after spinal cord injury, by blocking the inflammatory response in the spinal cord.

20 May 2022

AAN issues new guideline on oral and topical treatments for painful diabetic neuropathy

Diabetic neuropathy refers to nerve damage due to diabetes and it may lead to pain and numbness, most often in the hands and feet. To help neurologists and other doctors determine the best treatment for people with diabetic neuropathy, the American Academy of Neurology (AAN) has issued a guideline on oral and topical treatments for painful diabetic neuropathy.

28 Dec 2021

New pain management regimen reduced opioid exposure in trauma patients

A pain management regimen comprised mostly of over-the-counter medication reduced opioid exposure in trauma patients while achieving equal levels of pain control, according to a new study by physician-researchers at The University of Texas Health Science Center at Houston (UTHealth).

22 Jan 2021

Some of the main osteoporosis treatments could have a protective effect against COVID-19

Some of the principal treatments for osteoporosis, denosumab, zoledronate and calcium, could have a protective effect against COVID-19 in patients who take them, specifically a 30 to 40% reduction in the rate of infection, according to the results of a joint study by Hospital del Mar, the Hospital del Mar Medical Research Institute (IMIM), Pompeu Fabra University and the Pere Virgili Health Park.

3 Nov 2020

Increase in out-of-pocket costs associated with lower adherence to neurologic medications

As out-of-pocket costs go up for drugs for the neurologic disorders Alzheimer's disease, peripheral neuropathy and Parkinson's disease, people are less likely to take the drugs as often as their doctors prescribed, according to a study funded by the American Academy of Neurology and published in the February 19, 2020, online issue of Neurology, the medical journal of the American Academy of Neurology.

19 Feb 2020

Gabapentin – a drug for nerve pain could help patients with spinal injury finds study

A preclinical study with mice has shown that Gabapentin, a drug that is commonly used in nerve pain could be useful for patients with spinal cord injury. Use of the drug showed improvement in upper limb function among the mice models of spinal cord injury, wrote the researchers. The study titled, “Gabapentinoid treatment promotes corticospinal plasticity and regeneration following murine spinal cord injury,” was published this week in the latest issue of the Journal of Clinical Investigation.

4 Dec 2019

Common drug for nerve pain could help restore upper limb function after spinal cord injury

Long-term treatment with gabapentin, a commonly prescribed drug for nerve pain, could help restore upper limb function after a spinal cord injury, new research in mice suggests.

3 Dec 2019

Anti-epileptic drugs linked to increase in patients' risk of suicide

Three of the most common forms of anti-epileptic drugs in Denmark is associated with increase in patients' risk of suicide. However, the risk is low and should be seen in conjunction with the many beneficial effects of the medicines.

21 Nov 2019

Gabapentinoid medications increasingly prescribed off-label for adults with cancer

Between 2005 and 2015, as the opioid crisis in America came into focus, prescriptions for gabapentinoid medications -- gabapentin and pregabalin -- to adults with cancer saw a two-fold increase, a University of Michigan Rogel Cancer Center study has found.

29 Oct 2019

Penn Medicine awarded $22 million to apply scientific solutions to reverse opioid crisis

The nation has been grappling with the opioid epidemic for years-;and the city of Philadelphia has been hit hard by the crisis. While data is showing slight declines in overdose deaths, the opioid crisis remains a public health emergency.

4 Oct 2019

FDA grants approval for generic versions of Lyrica

On July 19, the U.S. Food and Drug Administration approved multiple applications for first generics of Lyrica (pregabalin) for the management of neuropathic pain associated with diabetic peripheral neuropathy, for the management of postherpetic neuralgia, as an adjunctive therapy for the treatment of partial onset seizures in patients 17 years of age and older, for the management of fibromyalgia, and for the management of neuropathic pain associated with spinal cord injury.

22 Jul 2019

Alzheimer's patients using antiepileptic drugs have twice the risk of pneumonia, study shows

People with Alzheimer's disease using antiepileptic drugs have twice the risk of pneumonia compared to non-users, a new study from the University of Eastern Finland shows.

21 Mar 2019

Some clinical trials may promote use of ineffective and costly treatments, researchers say

A new paper published by McGill University researchers in JAMA Internal Medicine suggests that some clinical trials may promote the use of ineffective and costly treatments. That's the opposite of what clinical trials are aimed at, namely preventing ineffective and costly treatments from being taken up by physicians and patients.

27 Nov 2018