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UH researcher aims to revolutionize treatment regimens for triple-negative breast cancer

A researcher at the University of Houston College of Pharmacy Drug Discovery Institute is working to revolutionize treatment regimens for triple-negative breast cancer (TNBC) by proving that nebivolol, an FDA-approved drug for high blood pressure, is effective in treating it.

31 Jan 2024

Are younger women experiencing a higher incidence of breast cancer?

Researchers evaluated the incidence of breast cancer among young women between the ages of 20 and 49 years. They assessed the incidence according to age at diagnosis, tumor stage, estrogen and progesterone hormone receptor status, and race and ethnicity.

31 Jan 2024

New review aims to help clinicians diagnose and manage PCOS

A recent review article in CMAJ explores the state of current knowledge on the diagnosis and treatment of this chronic disorder.

30 Jan 2024

Study identifies genetic variants that influence response to preterm birth treatment

A UC San Francisco-led study has for the first time identified genetic variants that predict whether patients will respond to treatment for preterm birth, a condition that affects one in 10 infants born in the United States.

22 Jan 2024

Does space travel impact the human reproductive system?

How space travel, space radiation, and microgravity affect human reproductive functions.

22 Jan 2024

Evaluating the effectiveness and safety of single-port robot-assisted technique in nipple-sparing mastectomy procedures

Researchers evaluated the safety and feasibility of a single-port (SP) robotic-assisted approach for performing nipple-sparing mastectomies (NSM).

19 Jan 2024

Hundreds of chemicals linked to breast cancer risk identified in new study

Study identifies 921 chemicals potentially linked to breast cancer risk, using a framework evaluating genotoxicity and endocrine activity.

14 Jan 2024

Combining immunotherapy and radiation to tackle aggressive triple-negative breast cancer

Cedars-Sinai Cancer investigators have analyzed the cells within triple-negative breast cancer tumors before and after radiation therapy with immunotherapy, identifying three patient groups with different responses to the treatment.

8 Jan 2024

Phthalate exposure before conception linked to reduced fertility and hormonal imbalances in women

Study examines the impact of preconception phthalate exposure on women's reproductive health, revealing associations with reduced fecundability, hormonal changes, and increased oxidative stress and inflammation.

1 Jan 2024

Scientists find sparse research on women and exercise at all

There is no shortage of advice for women on what to eat, how to train, or what supplements to take during their menstrual cycles, but a new review by an international team of scientists has found little evidence to support such recommendations.

5 Dec 2023

Cannabis shows promise in easing endometriosis pain, new research suggests

The Journal of Clinical Medicine review explores cannabis as a self-management strategy for endometriosis pain, revealing its potential to reduce gut inflammation and improve gut permeability, thereby alleviating bloating and suppressing pain through interactions with the endocannabinoid system and gut microbiota.

14 Nov 2023

Hormonal contraceptives taken by adolescents may affect risk assessment behavior

Hormonal contraceptives taken by adolescents may influence development of the brain in a way that alters the recognition of risks, a new study in rats suggests.

13 Nov 2023

Managing menopause: The 2023 toolkit for healthcare practitioners

The authors of the revised 2023 Toolkit extracted key recommendations from professional guidelines and positions as well as consensus statements on menopause and related conditions that have emerged since 2014.

1 Nov 2023

Paxlovid treatment provides protection against COVID-19 for both mother and child

A new mouse model of infection with the COVID-19-causing SARS-CoV-2 virus during pregnancy tracks closely the disease course doctors have observed in SARS-CoV-2-infected pregnant patients, and suggests that treatment with the antiviral Paxlovid provides protection for both mother and child.

16 Oct 2023

Saliva test breakthrough: Early detection for ectopic pregnancies on the horizon

Salivary proteins may offer early detection for ectopic pregnancies, potentially saving maternal lives through a non-invasive diagnostic approach. The study identifies specific proteins that are prominently present in ruptured ectopic pregnancy cases, highlighting the potential for developing a saliva-based diagnostic kit.

9 Oct 2023

Pregnancy hormones 'rewire' the brain to prepare for motherhood, research shows

Researchers at the Francis Crick Institute have shown that pregnancy hormones 'rewire' the brain to prepare mice for motherhood.

5 Oct 2023

Key player in ovarian cancer may have implications for PCOS

Researchers explore the involvement and altered expression of BBOX1-AS1 and microRNA-19b in polycystic ovary syndrome.

26 Sep 2023

Transforming postpartum depression treatment with neurosteroids

A new study in Neuropsychopharmacology delves into the mechanisms of action of brexanolone, the first FDA-approved, rapid-acting antidepressant specifically for postpartum depression (PPD). The research highlights brexanolone's potential anti-inflammatory effects and its impact on GABAA receptors, offering insights into its efficacy and suggesting avenues for further study.

19 Sep 2023

Research demonstrates a double-acting mechanism for fighting triple-negative breast cancer

Zachary Schug, Ph.D., assistant professor in the Molecular and Cellular Oncogenesis Program of the Ellen and Ronald Caplan Cancer Center at The Wistar Institute, has published a new paper in the journal Nature Cancer.