Progesterone News and Research

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Are reproductive factors and endometrial cancer risk associated?

The association between specific reproductive factors and the risk of endometrial cancer among women.

8 Sep 2023

Keto diet may lower testosterone levels in women with PCOS

The ketogenic (keto) diet may lower testosterone levels in women with polycystic ovary syndrome (PCOS), according to a new paper published in the Journal of the Endocrine Society.

8 Sep 2023

Rethinking menopause: Experts call for individualized treatment and more research

A comprehensive review in the journal Cell provides an in-depth look at the biology, clinical outcomes, and treatment options for menopause, including the effects of hormonal changes on metabolic and cognitive functions. The article also discusses various therapeutic interventions, from hormone therapy to alternative medicines, and their efficacy in managing menopausal symptoms.

7 Sep 2023

Vagus nerve stimulation shows mixed results in lowering stress hormone aldosterone

The study explored the effects of acute transcutaneous vagus nerve stimulation (tVNS) on serum aldosterone levels in both younger and older adults. While active tVNS did lead to a reduction in aldosterone levels, the changes were not significantly different from those observed in sham treatments, with aldosterone levels also varying based on age and sex.

4 Sep 2023

Review explores relationship between sleep disorders and pregnancy

A recent review summarizes what is known about these conditions and suggests future research directions and opportunities.

23 Aug 2023

Less is more: Radiotherapy omission deemed safe for certain breast cancer patients

The risk of breast cancer recurrence after breast-conserving surgery.

22 Aug 2023

Some early-stage, low-risk breast cancer patients may not need radiotherapy after surgery

Some women with early-stage, low-risk breast cancer may not need radiotherapy after breast conserving surgery according to new research led by McMaster University, BC Cancer, Hamilton Heath Sciences, and the University of British Columbia.

16 Aug 2023

Scientists develop synthetic extracellular matrix to support growth of mini endometrium in a dish

Scientists have developed a synthetic extracellular matrix (ECM) that can support the growth of a mini endometrium in a dish for at least two weeks.

11 Aug 2023

The role of estrogen in osteoarthritis and lower back pain

Researchers review existing evidence on the association between estrogen, osteoarthritis, and lower back pain.

10 Aug 2023

The impact of epigenetic features on breast cancer treatment and outcomes

The impact of epigenetic features on breast cancer treatment and outcomes.

9 Aug 2023

NCI funds study to investigate the underlying cellular mechanisms that drive ER+ breast cancer

The National Cancer Institute (NCI) has awarded a 5-year, $2.7 million grant to researchers at Sanford Burnham Prebys to investigate and elucidate the underlying cellular mechanisms that drive the most common form of breast cancer.

7 Aug 2023

Core promoter variation may drive development of triple-negative breast cancer

TNBC is a particularly aggressive subtype of breast cancer, characterized by the absence of three key receptors: estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2).

26 Jul 2023

Cervical fibroblasts in cervical insufficiency patients show impaired responses to progesterone

The study described in Scientific Reports highlights an impaired response to the hormone progesterone (P4) in cervical fibroblasts from patients with refractory cervical insufficiency (CI).

26 Jul 2023

New drug could overcome resistance to CDK4/6 inhibitors in breast cancer

Brest cancer is the most common cancer in women. Among breast tumors that spread to other organs (develop metastasis), 70% belong to a variant, called luminal, whose cells are sensitive to the female sex hormones estrogen and progesterone. In fact, the tumor forms when these hormones order the cells to divide.

14 Jul 2023