Prophylaxis News and Research

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Hypertension drug shown to prevent post-traumatic headaches

A study led by VA Puget Sound Health Care System researchers has shown that prazosin, a drug used to treat high blood pressure, can prevent posttraumatic headaches.

21 Jun 2023

Phase 3 clinical trial shows favorable safety and immunogenicity profile of single-shot live-attenuated chikungunya vaccine

Researchers performed a double-blinded, phase III randomized trial.

15 Jun 2023

Letermovir: A promising breakthrough in CMV prevention for kidney transplant recipients

In a recent article published in the journal JAMA Network, researchers performed a randomized clinical trial (RCT) to demonstrate the noninferiority of letermovir vs. valganciclovir for prophylaxis of cytomegalovirus (CMV) in adult CMV-seronegative kidney transplant recipients (KTRs) who received a kidney from a CMV-seropositive individual.

13 Jun 2023

Antiretroviral treatment efficiently suppresses penile HIV replication

Of the 38 million people worldwide living with HIV, approximately 700,000 are newly infected men, primarily via sexual transmission.

12 Jun 2023

Vaccine against deadly chytrid fungus shifts microbiome to make frogs more resilient to future exposure

A human or animal's microbiome -; the collection of often beneficial microorganisms, including as bacteria and fungi, that live on or within a host organism -; can play an important role in the host's overall immune response, but it is unclear how vaccines against harmful pathogens impact the microbiome.

11 Jun 2023

Is healthy sleep, both before and during the COVID-19 pandemic, prior to SARS-CoV-2 infection, protective against post–COVID-19 condition?

Researchers examined the relationship between multidimensional sleep health and post-coronavirus disease 2019 condition.

1 Jun 2023

CDC reports on its Mpox response

Research paper provides an overview of the U.S. monkeypox outbreak, highlighting the rapid response, vaccination efforts, and racial disparities in cases. Ongoing surveillance, vaccination, and communication are emphasized as crucial for future prevention.

24 May 2023

JYNNEOS vaccine shows strong effectiveness against Mpox in New York outbreak

In the recent Morbidity and Mortality Weekly Report (MMWR) published by the Centers for Disease Control and Prevention (CDC), researchers reported on JYNNEOS vaccine effectiveness (VE) against Mpox infections among New York (NY) residents in 2022.

23 May 2023

Real-world assessment of JYNNEOS vaccine effectiveness during the 2022 mpox outbreak in the US

A recent study published in Morbidity and Mortality Weekly Report estimated the efficacy of the JYNNEOS vaccine against mpox.

22 May 2023

Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses

Researchers generated six human monoclonal antibodies that prevented infection.

17 May 2023

Understanding the adverse events profile of MVA-BN vaccine for Mpox

Researchers evaluated adverse events following the Modified Vaccinia Ankara-Bavarian Nordic (MVA-BN) vaccination for mpox.

10 May 2023

New guidance recommends the discontinuation of antibiotics after closure of incisions

Antibiotics administered before and during surgery should be discontinued immediately after a patient's incision is closed, according to updated recommendations for preventing surgical site infections.

5 May 2023

Discontinuing oral antibiotics after breast reconstruction does not lead to an increase in infections

For breast cancer patients undergoing breast reconstruction after mastectomy, avoiding postoperative oral antibiotics does not reduce the risk of infections, reports a study in the May issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons.

27 Apr 2023

US officials want to end the HIV epidemic by 2030. Many stakeholders think they won’t.

In 2018, Mike Ferraro was living on the street and sharing needles with other people who injected drugs when he found out he was HIV-positive.

24 Apr 2023

Study reveals alarming global burden of antimicrobial resistance in bacterial infections

The paper presents a systematic analysis of the global burden of bacterial antimicrobial resistance in 2019. The authors highlight the urgent need for action to address this growing public health threat.

23 Apr 2023

HIV diagnoses increases more than three-fold after implementing targeted testing in EDs

Targeted testing for HIV in emergency departments has great potential for increasing diagnoses, this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Copenhagen, Denmark, (15-18 April), will hear.

10 Apr 2023

No-cost preventive services are now in jeopardy. Here’s what you need to know.

When a federal judge in Texas declared unconstitutional a popular part of the Affordable Care Act that ensures no-cost preventive care for certain services, such as screening exams for conditions such as diabetes, hepatitis, and certain cancers, it left a lot of people with a lot of questions.

7 Apr 2023

Post-exposure doxycycline approach leads to two-thirds reduction in STI incidence

The oral antibiotic doxycycline prevented the acquisition of sexually transmitted infections (STIs) when tested among men who have sex with men (MSM) and transgender women who took the medication within 72 hours of having condomless sex, according to findings published today in the New England Journal of Medicine.

6 Apr 2023

World Health Day: Giving Universal Health Coverage a Platform

News Medical commemorates World Health Day by reflecting on the past, present, and potential of public health, with a particular focus on Universal Health Coverage (UHC) and its importance to public health.