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Non-coding RNAs play key role in maintaining proper balance between fighting infection and inflammation

Non-coding RNAs play key role in maintaining proper balance between fighting infection and inflammation

Special RNA molecules called long non-coding RNAs (lncRNAs) are key controllers for maintaining immune health when fighting infection or preventing inflammatory disorders, according to research led by Jorge Henao-Mejia, MD, PhD, an assistant professor of Pathology and Laboratory Medicine in the Perelman School of Medicine at the University of Pennsylvania. [More]
Type of bacteria in the gut may increase or decrease risk of developing celiac disease

Type of bacteria in the gut may increase or decrease risk of developing celiac disease

About 40 per cent of the population have a genetic disposition to celiac disease, but only about one per cent develop the autoimmune condition when exposed to gluten, and this could be promoted by the type of bacteria present in the gut. [More]
HMS study reveals key instigator of nerve cell damage in ALS patients

HMS study reveals key instigator of nerve cell damage in ALS patients

Scientists from Harvard Medical School have identified a key instigator of nerve cell damage in people with amyotrophic lateral sclerosis, or ALS, a progressive and incurable neurodegenerative disorder. [More]
UT Southwestern researchers discover protein that can promote healthful breakdown of fat

UT Southwestern researchers discover protein that can promote healthful breakdown of fat

Researchers at UT Southwestern Medical Center have found that a protein often located on the surface of fat droplets within cells - and especially abundant in the muscles of endurance athletes - can kick-start the more efficient and healthful breakdown of fat. [More]
Researchers identify brain circuit that helps take major developmental step despite nutritional stress

Researchers identify brain circuit that helps take major developmental step despite nutritional stress

When we go hungry, we have the ability to ignore the urge to eat such that we can carry out the task at hand. It has long been known that the brain is involved in such decisions. [More]
New imaging technique may help detect amyloid-related heart failure

New imaging technique may help detect amyloid-related heart failure

A type of heart failure caused by a build-up of amyloid can be accurately diagnosed and prognosticated with an imaging technique, eliminating the need for a biopsy, according to a multicenter study led by researchers at Columbia University Medical Center. [More]
Assigning barcode to stem cells makes it possible to monitor large blood cell populations

Assigning barcode to stem cells makes it possible to monitor large blood cell populations

By assigning a barcode to stem cells, researchers at Lund University in Sweden have made it possible to monitor large blood cell populations as well as individual blood cells, and study the changes over time. [More]
New chemical compound could potentially be used to treat Ebola virus infection

New chemical compound could potentially be used to treat Ebola virus infection

Scientists have found Ebola's Achilles' heel: a new kind of chemical compound can block the protein Ebola uses to break out of cells and infect new cells. [More]
EPFL scientists discover new path to combat pathogenic bacteria

EPFL scientists discover new path to combat pathogenic bacteria

Bacteria that cause tuberculosis, leprosy and other diseases, survive by switching between two different types of metabolism. [More]
Scientists move a step closer to translating BubR1 protein's function into potential cancer therapy

Scientists move a step closer to translating BubR1 protein's function into potential cancer therapy

In a paper published recently in the journal eLife, Mayo Clinic scientists take a step toward translating the protein BubR1's function into a potential therapy for cancer. [More]
Researchers investigate link between diet, obesity-linked Type 2 diabetes, and spinal disc degeneration

Researchers investigate link between diet, obesity-linked Type 2 diabetes, and spinal disc degeneration

Can a diet high in processed fat and sugar and Type 2 diabetes cause degeneration of intervertebral discs in the spine? If so, what is happening, and can it be prevented? As part of an ongoing collaboration between Rensselaer Polytechnic Institute and the Icahn School of Medicine at Mount Sinai - a partnership that draws upon the expertise of both schools to address significant health problems - researchers hope to answer those questions by investigating the link between diet, obesity-linked Type 2 diabetes, and intervertebral disc degeneration. [More]
Scientists find how sleep deprivation negatively affects memory

Scientists find how sleep deprivation negatively affects memory

Researchers from the Universities of Groningen and Pennsylvania have discovered a piece in the puzzle of how sleep deprivation negatively affects memory. [More]
TMDU researchers inject gelatin-based gel carrying protein/peptide drugs to trigger bone augmentation

TMDU researchers inject gelatin-based gel carrying protein/peptide drugs to trigger bone augmentation

The part of the jawbone containing tooth sockets is known as alveolar bone, and its loss over time or following dental disease may ultimately result in tooth loss. [More]
Novel innovation could help scientists study new treatments for mitochondrial diseases

Novel innovation could help scientists study new treatments for mitochondrial diseases

A new study published in the Proceedings of the National Academy of Sciences from the University of Missouri has succeeded in creating embryos with "heteroplasmy," or the presence of both maternal and paternal mitochondrial DNA. [More]
Drinking green tea could prevent abdominal aortic aneurysm

Drinking green tea could prevent abdominal aortic aneurysm

Japan's favorite beverage might be offering more than just a relaxing tea break. [More]
Research finding opens door to new treatment options for inflammatory rheumatism

Research finding opens door to new treatment options for inflammatory rheumatism

Enthesitis, inflammation of tendons where they attach to the bone, is a common medical problem which underlies various forms of inflammatory rheumatism. [More]
Researchers discover new role of cellular signaling molecule involved in release of hunger hormone

Researchers discover new role of cellular signaling molecule involved in release of hunger hormone

Researchers at UT Southwestern Medical Center have identified a previously unknown role of a cellular signaling molecule involved in release of the "hunger hormone" ghrelin, a finding that could have implications for optimal treatment of children taking beta blockers. [More]
NIH researchers discover rare, lethal inflammatory disease that affects young children

NIH researchers discover rare, lethal inflammatory disease that affects young children

National Institutes of Health researchers have discovered a rare and sometimes lethal inflammatory disease - otulipenia - that primarily affects young children. They have also identified anti-inflammatory treatments that ease some of the patients' symptoms: fever, skin rashes, diarrhea, joint pain and overall failure to grow or thrive. [More]
Scientists reveal role of lysosomal vesicles in spread of Parkinson's disease

Scientists reveal role of lysosomal vesicles in spread of Parkinson's disease

Scientists from the Institut Pasteur have demonstrated the role of lysosomal vesicles in transporting α-synuclein aggregates, responsible for Parkinson's and other neurodegenerative diseases, between neurons. [More]
Study may show ways to maintain immunity in older people

Study may show ways to maintain immunity in older people

A study from Oxford and Basel universities may point the way to maintaining our immune systems as we get older. [More]
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