Protein Aggregation News and Research

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Cold temperature plays a central role in longevity

Cold activates a cellular cleansing mechanism that breaks down harmful protein aggregations responsible for various diseases associated with aging.

3 Apr 2023

Exploring the neuroprotective potential of cell-penetrating peptides, extracellular vesicles, and micro ribonucleic acids

In a recent review published in Biomedicines, researchers explored extracellular vesicles (EVs), cell-penetrating peptides (CPPs), and micro ribonucleic acids (miRNAs) as therapies for neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD).

1 Mar 2023

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

A new study in the journal Nature Communications aimed to analyze the aggregation propensity in the proteins of both SARS-CoV-2 and SARS-CoV.

21 Feb 2023

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

Researchers presented eight hallmarks of neurodegenerative diseases (NDDs), their in vivo biomarkers, and interactions to help categorize NDDs and specify patients within a specific NDD.

21 Feb 2023

Nanopore-based sensing device can provide volume information about tau and tubulin proteins

Tau and tubulin proteins are one of the leading causes of many neurodegenerative diseases, such as Alzheimer's and Parkinson's.

10 Jan 2023

Newly identified genetic mutation may be a root cause of severe childhood glaucoma

An international team of scientists led by Mass Eye and Ear, a member of Mass General Brigham, and Boston Children's Hospital, has discovered a new genetic mutation that may be a root cause of severe cases of childhood glaucoma, a devastating condition that runs in families and can rob children of their vision by 3 years of age.

1 Dec 2022

The roles of innate and adaptive immunity in Alzheimer’s disease development and progression

Researchers reviewed research advancements showing the significant role both innate and adaptive immune systems play in the pathological course of Alzheimer’s disease.

10 Nov 2022

Research shows how a very low dose of rhenium metal complex kills ovarian cancer cells

Metal-containing complexes have taken up center stage in the search for new cancer drugs that are as free of side effects as possible.

12 Oct 2022

Repligen expands process analytics portfolio with DRS Daylight Solutions agreement

Repligen Corporation, a life sciences company focused on bioprocessing technology leadership, today announced it has entered into a strategic partnership and exclusive license agreement with DRS Daylight Solutions to expand the use of mid-infrared (mid-IR) technology in the bioprocessing market.

From Daylight Solutions Inc 22 Sep 2022

SARS-CoV-2 generates amyloid in cerebral spinal fluid

In a recent study posted to the bioRxiv* preprint server, an international team of researchers demonstrated amyloid aggregation due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human cerebrospinal fluid (CSF).

20 Sep 2022

Molecular probes can track the progress of protein that misbehaves in neurodegenerative diseases

A team of researchers from the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) has designed in silico "molecular probes" able to track the progress of a protein that misbehaves in different neurodegenerative diseases, such as Amyotrophic Lateral Sclerosis (ALS) and Fronto-Temporal Dementia (FTD).

9 Sep 2022

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

Scientists review current literature associated with the role of the gut-brain axis in AD pathogenesis.

9 Aug 2022

DZNE and Intravacc receive € 2.5 million EU funding to develop a prototype ALS vaccine

DZNE and Intravacc B.V., a world leading contract development and manufacturing organization (CDMO) of preventive and therapeutic vaccines, have been awarded a funding of € 2.5 million from the European Union (EIC Transition Grant) to further develop a prototype ALS vaccine, including process development, scale-up, and toxicology study.

6 Jul 2022

Experimental drug more effective than existing FDA-approved medications for ALS

New research on the experimental drug, NU-9, invented and developed by two Northwestern University scientists to treat ALS (amyotrophic lateral sclerosis), shows it is more effective than existing FDA-approved drugs for the disease.

17 May 2022

The evolution of the SARS-CoV-2 spike protein

Researchers discuss the evolution and mechanisms of mutations that have occurred in the spike protein of SARS-CoV-2.

31 Mar 2022

Novel optobiological system may shine light on protein aggregation in Parkinson's disease

A novel system to control protein aggregation in a model of Parkinson's disease may answer longstanding questions about how the disease begins and spreads, according to a new study published March 9th in the open-access journal PLOS Biology by Abid Oueslati of Laval University, Quebec, Canada, and colleagues.

23 Mar 2022

Protein Aggregation News and Research

Cold temperature plays a central role in longevity

Exploring the neuroprotective potential of cell-penetrating peptides, extracellular vesicles, and micro ribonucleic acids

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

Nanopore-based sensing device can provide volume information about tau and tubulin proteins

Newly identified genetic mutation may be a root cause of severe childhood glaucoma

The roles of innate and adaptive immunity in Alzheimer’s disease development and progression

Research shows how a very low dose of rhenium metal complex kills ovarian cancer cells

Repligen expands process analytics portfolio with DRS Daylight Solutions agreement

SARS-CoV-2 generates amyloid in cerebral spinal fluid

Molecular probes can track the progress of protein that misbehaves in neurodegenerative diseases

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

DZNE and Intravacc receive € 2.5 million EU funding to develop a prototype ALS vaccine

Experimental drug more effective than existing FDA-approved medications for ALS

The evolution of the SARS-CoV-2 spike protein

Novel optobiological system may shine light on protein aggregation in Parkinson's disease

Cognitive decline found to be the key factor in predicting life expectancy for Alzheimer's patients

Optimizing bioprocessing with Raman spectroscopy

Advanced technique reveals the ultrastructure of huntingtin inclusion bodies

What impact does temperature have on SARS-CoV-2 M protein dynamics?

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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