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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.
MDA celebrates FDA approval of new spinal muscular atrophy drug

MDA celebrates FDA approval of new spinal muscular atrophy drug

The Muscular Dystrophy Association today celebrated news of the U.S. Food and Drug Administration's decision to grant approval for nusinersen (brand name Spinraza), the first disease-modifying drug to treat the most common genetic cause of death in infants. [More]
UC researchers uncover obesity-related protein's role in leukemia development

UC researchers uncover obesity-related protein's role in leukemia development

Cancer researchers at the University of Cincinnati College of Medicine have found an obesity-associated protein's role in leukemia development and drug response which could lead to more effective therapies for the illness. [More]
Mount Sinai researchers laying groundwork to find effective treatment for Zika virus

Mount Sinai researchers laying groundwork to find effective treatment for Zika virus

Researchers at the Icahn School of Medicine at Mount Sinai are working on the basic science that lays the groundwork to finding a way to treat and prevent the Zika virus, a global health risk. [More]
Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Diet-related diseases like non-alcoholic fatty liver disease (NAFLD) are known to have a major inflammatory component. [More]
Researchers creating computer model to track circadian clock

Researchers creating computer model to track circadian clock

Biology dictates that DNA creates proteins which create - among other things - metabolites, the outputs of metabolism. [More]
TSRI scientists develop new methods to design precision medicines against disease-causing RNAs

TSRI scientists develop new methods to design precision medicines against disease-causing RNAs

Scientists on the Florida campus of The Scripps Research Institute have developed broad methods to design precision medicines against currently incurable diseases caused by RNA. [More]
Researchers use CRISPR-based genetic screening to identify three promising HIV treatment targets

Researchers use CRISPR-based genetic screening to identify three promising HIV treatment targets

Investigators from Whitehead Institute, the Ragon Institute of MGH, MIT and Harvard and the Broad Institute of MIT and Harvard have used CRISPR-Cas9 gene-editing technology to identify three promising new targets for treatment of HIV infection. [More]
Scientists develop novel nanoparticle-based method to deliver DNA vaccine

Scientists develop novel nanoparticle-based method to deliver DNA vaccine

Scientists at Brigham and Women's Hospital have developed a novel method for delivering therapeutic molecules into cells. [More]
New ultrasensitive detection system of in-flow microRNAs uses encoded microgels

New ultrasensitive detection system of in-flow microRNAs uses encoded microgels

Single-stranded, noncoding micro-ribonucleic acids, consisting of 18-23 nucleotides, play a key role in regulating gene expression. [More]
Research finds link between p53 pathway and ribosome biogenesis, nucleotide metabolism in DBA

Research finds link between p53 pathway and ribosome biogenesis, nucleotide metabolism in DBA

Diamond Blackfan Anemia (DBA) is a condition that is characterized by a failure of the bone marrow to produce red blood cells, congenital abnormalities, and a predisposition to cancer. [More]
Study provides new insights into fundamental characteristics of dendritic cells

Study provides new insights into fundamental characteristics of dendritic cells

Dendritic cells represent an important component of the immune system: they recognize and engulf invaders, which subsequently triggers a pathogen-specific immune response. [More]
Researchers find new insights into silencing of X-chromosomes in human embryos

Researchers find new insights into silencing of X-chromosomes in human embryos

Researchers have discovered new insights into how one of the two X-chromosomes is silenced during the development of female human embryos and also in lab-grown stem cells. [More]
Multifunctional RNA nanoparticles could overcome treatment resistance in breast cancer, study shows

Multifunctional RNA nanoparticles could overcome treatment resistance in breast cancer, study shows

Researchers at the University of Cincinnati College of Medicine have been able to generate multifunctional RNA nanoparticles that could overcome treatment resistance in breast cancer, potentially making existing treatments more effective in these patients. [More]
Porvair sciences introduce products for use in animal and plant genetics

Porvair sciences introduce products for use in animal and plant genetics

Porvair Sciences will showcase two important technical breakthroughs at PAG XXV in San Diego (USA) from January 14-18, 2017. [More]
Oral cavity bacterium linked to development and progression of esophageal cancer

Oral cavity bacterium linked to development and progression of esophageal cancer

A type of bacterium usually found in the human mouth, Fusobacterium nucleatum, has been found to be related to the prognosis of esophageal cancer in Japanese patients by researchers from Kumamoto University, Japan. [More]
Researchers uncover first ‘off-switches’ for better control of CRISPR/Cas9 gene editing

Researchers uncover first ‘off-switches’ for better control of CRISPR/Cas9 gene editing

CRISPR/Cas9 genome editing is quickly revolutionizing biomedical research, but the new technology is not yet exact. The technique can inadvertently make excessive or unwanted changes in the genome and create off-target mutations, limiting safety and efficacy in therapeutic applications. [More]
Researchers crack genetic code of lung tissues to identify novel targets for treating IPF

Researchers crack genetic code of lung tissues to identify novel targets for treating IPF

Researchers cracked the complete genetic code of individual cells in healthy and diseased human lung tissues to find potential new molecular targets for diagnosing and treating the lethal lung disease Idiopathic Pulmonary Fibrosis (IPF). [More]
RNA modifications play significant role in function of nervous system

RNA modifications play significant role in function of nervous system

Researchers at the Institute of Molecular Biology and Johannes Gutenberg University Mainz have shown that a new way of regulating genes is vital for the activity of the nervous system. [More]
Scientists identify biomarkers to predict patient’s response to breast cancer treatment

Scientists identify biomarkers to predict patient’s response to breast cancer treatment

Why do some breast cancers respond to treatment while others resist it? A study led by researchers at the University of North Carolina Lineberger Comprehensive Cancer Center may provide insight into this important question. [More]
Scientists discover truncated p53 proteins that promote cancer growth and metastasis

Scientists discover truncated p53 proteins that promote cancer growth and metastasis

Discovered in the 1970s, tumor suppressors are among the most important proteins in the body. [More]
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