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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.
Researchers study how skin stem cells respond to forces

Researchers study how skin stem cells respond to forces

All cells share the same genetic code, no matter if they are skin or brain cells. However, these cells are exposed to very different types of mechanical environments and mechanical stresses. [More]
Research findings unveil new avenues to monitor, treat lung cancer more effectively

Research findings unveil new avenues to monitor, treat lung cancer more effectively

A team of researchers from Singapore has discovered a class of small RNA molecules, known as oncomiRs, which are responsible for fuelling lung cancer. [More]
Exosome research and quality control at Cell Guidance Systems use the ZetaView

Exosome research and quality control at Cell Guidance Systems use the ZetaView

Cell Guidance Systems (CellGS) provides innovative life science research tools and services. Their goal is to identify valuable innovations from research groups around the world and develop products that address unmet needs, providing new tools that expand the possibilities of life science research. [More]
JAX researchers find precise, reliable way to identify leukemia cells of origin

JAX researchers find precise, reliable way to identify leukemia cells of origin

Every cancer starts with a single cell, and Jackson Laboratory researchers have found a precise and reliable way -- whole-genome profiling of open chromatin -- to identify the kind of cell that leads to a given case of leukemia, a valuable key to cancer prognosis and outcome. [More]
Research opens up new ways to detect, inhibit cancer spread

Research opens up new ways to detect, inhibit cancer spread

Clusters of circulating cells commonly found in the blood of cancer patients have long been the subject of research on cancer. These clusters have been regarded for more than 50 years as malignant cells that have broken off from the primary tumor, spreading cancer to other parts of the body. [More]
Study finds microRNA let-7 plays key role in restricting neuroblastoma

Study finds microRNA let-7 plays key role in restricting neuroblastoma

Great strides have been made in treating neuroblastoma, the most common cancer in infants and toddlers. However, advanced cases are often fatal, and children who survive often face life-long physical and intellectual challenges related to their treatment. [More]
Study results pave way to development of effective human vaccine against HIV

Study results pave way to development of effective human vaccine against HIV

A new scientific study conducted by a team of leading AIDS scientists reveal results that lead the way to the development of an effective human vaccine against human immunodeficiency virus (HIV). [More]
Study shows miR-19 helps new neurons in the adult brain stay on track

Study shows miR-19 helps new neurons in the adult brain stay on track

A small stretch of ribonucleic acid called microRNA could make the difference between a healthy adult brain and one that's prone to disorders including schizophrenia. [More]
New topical film patch can effectively close dermal wounds, reduce scarring

New topical film patch can effectively close dermal wounds, reduce scarring

Currently there is no product available based on polymer film containing active molecules to accelerate dermal wound healing that also reduces the scar formation. [More]
Extra-coding RNA modulates neuronal DNA methylation patterns

Extra-coding RNA modulates neuronal DNA methylation patterns

The creation of memories in the brain involves addition or removal of methyl groups at precise spots on chromosomal DNA. But what controls the careful targeting of these neuronal DNA methylation dynamics? [More]
PREVAIL IV trial opens in Liberia for EVD survivors with persistent traces of Ebola virus RNA

PREVAIL IV trial opens in Liberia for EVD survivors with persistent traces of Ebola virus RNA

The Partnership for Research on Ebola Virus in Liberia, a U.S.-Liberia joint Clinical Research Partnership, today announced the opening of PREVAIL IV, a treatment trial for men who have survived Ebola virus disease (EVD) but continue to have evidence of Ebola virus genetic material, RNA, in their semen. [More]
Researchers find distinct, non-identical differences among retroviruses

Researchers find distinct, non-identical differences among retroviruses

In the most comprehensive study of its kind, researchers in the report that most types of retroviruses have distinct, non-identical virus structures. [More]
Researchers identify potential biomarker for Parkinson's disease in biobanked urine samples

Researchers identify potential biomarker for Parkinson's disease in biobanked urine samples

For more than five years, urine and cerebral-spinal fluid samples from patients with Parkinson's disease have been locked in freezers in the NINDS National Repository, stored with the expectation they might someday help unravel the still-hidden course of this slow-acting neurodegenerative disease. [More]
Penn researchers develop low-cost genetic test for Zika virus

Penn researchers develop low-cost genetic test for Zika virus

University of Pennsylvania engineers have developed a rapid, low-cost genetic test for the Zika virus. [More]
Alnylam reports new results from investigational RNAi therapeutic programs

Alnylam reports new results from investigational RNAi therapeutic programs

Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, announced today preliminary results from its ongoing Phase 2 open-label extension (OLE) studies with patisiran and revusiran, both investigational RNAi therapeutics targeting transthyretin (TTR) for the treatment of hereditary TTR-mediated amyloidosis (hATTR amyloidosis). [More]
MIT engineers develop new way to visualize RNA molecules in higher resolution

MIT engineers develop new way to visualize RNA molecules in higher resolution

Cells contain thousands of messenger RNA molecules, which carry copies of DNA's genetic instructions to the rest of the cell. MIT engineers have now developed a way to visualize these molecules in higher resolution than previously possible in intact tissues, allowing researchers to precisely map the location of RNA throughout cells. [More]
Novel technique could help discover genes linked to complex traits in any animal model

Novel technique could help discover genes linked to complex traits in any animal model

Mice are one of the most commonly used laboratory organisms, widely used to study everything from autism to infectious diseases. Yet genomic studies in mice have lagged behind those in humans. [More]
Researchers identify non-coding RNA NEAT1 as potential drug target to combat cancer

Researchers identify non-coding RNA NEAT1 as potential drug target to combat cancer

A team of researchers led by professor Jean-Christophe Marine has identified NEAT1, a non-coding RNA, as a potential therapeutic target in the fight against cancer. [More]
Novel high-resolution method helps study which genes are active in tissues

Novel high-resolution method helps study which genes are active in tissues

Scientists at Karolinska Institutet and the Royal Institute of Technology have devised a new high-resolution method for studying which genes are active in a tissue. [More]
Study focuses on critical proteins involved in ovarian cancer biology

Study focuses on critical proteins involved in ovarian cancer biology

In what is believed to be the largest study of its kind, scientists at the Pacific Northwest National Laboratory, Johns Hopkins University and their collaborators from institutions across the nation have examined the collections of proteins in the tumors of 169 ovarian cancer patients to identify critical proteins present in their tumors. [More]
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