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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Neuroscientists map brain's sensory gatekeeper in unprecedented detail

Many people with autism experience sensory hypersensitivity, attention deficits, and sleep disruption. One brain region that has been implicated in these symptoms is the thalamic reticular nucleus (TRN), which is believed to act as a gatekeeper for sensory information flowing to the cortex.

22 Jul 2020

Experts use genomic analysis tools to create personalized treatment for kidney cancer patients

Experts at City of Hope and the Translational Genomics Research Institute are using one of the world's most comprehensive genomic analysis tools to map out personalized treatment plans for metastatic kidney cancer patients.

22 Jul 2020

New pathways that could help treat RNA viruses identified

Researchers at the University of New Hampshire have identified new pathways in an RNA-based virus where inhibitors, like medical treatments, unbind.

22 Jul 2020

Vitamin D could help suppress excessive T cell-mediated lung inflammation in severe COVID-19

As COVID-19 continues to spread over the world scientists continue to seek the reasons for the difference in disease severity from person to person.

22 Jul 2020

Monash University researchers pave way for affordable immunotherapies

Researchers from Monash University’s Institute of Pharmaceutical Sciences are paving the way for accessible and affordable cancer treatment by using powerful nanoscale tools to overcome the high costs and long lead-times associated with one of the world’s newest forms of immunotherapy: CAR-T cell therapy.

22 Jul 2020

Silver-plated gold nanostars could be used to identify early biomarkers of cancer

Biomedical engineers at Duke University have engineered a method for simultaneously detecting the presence of multiple specific microRNAs in RNA extracted from tissue samples without the need for labeling or target amplification.

21 Jul 2020

Stanford researchers develop a portable device for rapidly detecting blood ammonia levels

Seated around the dinner table, faculty affiliated with Stanford ChEM-H - one of Stanford University's interdisciplinary institutes - spoke one-by-one, pitching ideas for collaborative research.

21 Jul 2020

Pfizer/BioNTech COVID-19 vaccine elicits both neutralizing antibodies and T cell response

A new study published on the preprint server medRxiv by a research group from the U.S. and Germany indicates that a novel BNT162b1 RNA-based vaccine against coronavirus disease (COVID-19) induces functional and proinflammatory T cell responses in almost all participants – marking another landmark achievement for this promising vaccine candidate.

21 Jul 2020

Nitric oxide treatment can be pivotal in the fight against COVID-19

Nitric oxide treatment can be pivotal in the world's fight against SARS-CoV-2, the coronavirus that causes COVID-19, according to a review from the George Washington University (GW). The article is published in the journal Nitric Oxide.

21 Jul 2020

Promega Maxwell Extraction System added to CDC COVID-19 diagnostic protocol

Promega Corporation’s Maxwell RSC 48 Instrument and Maxwell RSC Viral Total Nucleic Acid Purification Kit are now in the Centers for Disease Control and Prevention’s COVID-19 diagnostic protocol for emergency use.

From Promega Corporation 21 Jul 2020

Analysis of the SARS-CoV-2 proteome via visual tools

Now, a new study published on the preprint server bioRxiv* in July 2020 shows how this can be advanced at a greater speed by combining experimental results with homology models obtained by high-throughput pipelines. This will help produce new hypotheses that will show novel druggable targets for effective drug development.

21 Jul 2020

A multi-omics single cell analysis on COVID-19

Now, a new study published on the preprint server medRxiv aims to analyze the immune response over time, using multi-omics in the study of a single cell.

21 Jul 2020

Advanced cryo-EM imaging reveals high-resolution structure of viral RNA replication complex

For the first time, scientists at the Morgridge Institute for Research have generated near atomic resolution images of a major viral protein complex responsible for replicating the RNA genome of a member of the positive-strand RNA viruses, the large class of viruses that includes coronaviruses and many other pathogens.

20 Jul 2020

An abundance of biomolecules linked to COVID-19 status and severity

Tapping into the potential of the multi-omic method to uncover functional connections between various classes of biomolecules, researchers from notable institutions in the United States have discovered sets of co-varying molecules that shed light on coronavirus disease (COVID-19) pathophysiology and provide treatment opportunities.

20 Jul 2020

COVID-19 vaccine displays protective traits in nonhuman primates

A replicating RNA vaccine, formulated with a lipid-based nanoparticle emulsion that goes by the acronym LION, produces antibodies against the COVID-19 coronavirus in mice and primates with a single immunization. These antibodies potently neutralize the virus.

20 Jul 2020

Using AI to pinpoint neurons involved in gait reacquisition

Researchers at EPFL are able to get paralyzed rodents walking again by stimulating the animals' damaged spinal cords.

20 Jul 2020

McGill researchers discover bacterial organelles involved in gene expression

Researchers at McGill University have discovered bacterial organelles involved in gene expression, suggesting that bacteria may not be as simple as once thought.

20 Jul 2020

New assay improves detection of SARS-CoV-2 antibodies

Researchers at the University of California Santa Cruz have developed a new assay for the detection of antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that they say provides significant advantages over the techniques currently used.

20 Jul 2020

Australian researches detect SARS-CoV-2 virus in wastewater from planes and cruise ships

Previous reports have shown that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19), has been found in untreated wastewater. While the data is limited, there are no reported cases of a person becoming infected with the virus due to exposure to contaminated water.

20 Jul 2020

Novel nanospectroscopy measures biomolecular changes induced by drugs in human cells

Synchrotron InfraRed Nanospectroscopy has been used for the first time to measure biomolecular changes induced by a drug (amiodarone) within human cells (macrophages) and localized at 100 nanometre scale, i.e. two orders of magnitude smaller than the IR wavelength used as probe.

17 Jul 2020

RNA News and Research

Further Reading

Neuroscientists map brain's sensory gatekeeper in unprecedented detail

Experts use genomic analysis tools to create personalized treatment for kidney cancer patients

New pathways that could help treat RNA viruses identified

Vitamin D could help suppress excessive T cell-mediated lung inflammation in severe COVID-19

Monash University researchers pave way for affordable immunotherapies

Silver-plated gold nanostars could be used to identify early biomarkers of cancer

Stanford researchers develop a portable device for rapidly detecting blood ammonia levels

Pfizer/BioNTech COVID-19 vaccine elicits both neutralizing antibodies and T cell response

Nitric oxide treatment can be pivotal in the fight against COVID-19

Promega Maxwell Extraction System added to CDC COVID-19 diagnostic protocol

Analysis of the SARS-CoV-2 proteome via visual tools

A multi-omics single cell analysis on COVID-19

Advanced cryo-EM imaging reveals high-resolution structure of viral RNA replication complex

An abundance of biomolecules linked to COVID-19 status and severity

COVID-19 vaccine displays protective traits in nonhuman primates

Using AI to pinpoint neurons involved in gait reacquisition

McGill researchers discover bacterial organelles involved in gene expression

New assay improves detection of SARS-CoV-2 antibodies

Australian researches detect SARS-CoV-2 virus in wastewater from planes and cruise ships

Novel nanospectroscopy measures biomolecular changes induced by drugs in human cells

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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