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Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

Study links acid-reducing drugs to increased risk of migraine

People who take acid-reducing drugs may have a higher risk of migraine and other severe headache than people who do not take these medications, according to a study published in the April 24, 2024, online issue of Neurology Clinical Practice, an official journal of the American Academy of Neurology.

24 Apr 2024

Prostaglandin E2: The culprit behind tumor immune evasion

Tumors actively prevent the formation of immune responses by so-called cytotoxic T cells, which are essential in combating cancer. Researchers at the Technical University of Munich (TUM) and the Ludwig-Maximilians-Universität München (LMU) Hospital have now uncovered for the first time how this exactly happens.

24 Apr 2024

Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Researchers at Texas Children’s Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital and Houston Methodist published results of a phase I clinical trial of a novel immunotherapy for high-risk sarcomas in the journal Nature Cancer.

24 Apr 2024

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Intranasal administration of neomycin sulfate in murine models shows promise as a prophylactic and therapeutic agent against respiratory viruses like influenza A and SARS-CoV-2 by inducing interferon-stimulated gene (ISG) expression, independent of microbiota and interferon activation.

24 Apr 2024

Innovative peptide-based hydrogel therapy for virus prevention

Vaccines remain the gold standard of protection against dangerous pathogens, but take considerable time and vast resources to develop.

23 Apr 2024

U-M scientists develop new tool to better understand neuronal signaling

University of Michigan researchers have developed a new tool to better understand how chemicals like dopamine and epinephrine interact with neurons.

23 Apr 2024

New tool hunts for Alzheimer's clues in gut microbiome

Cleveland Clinic researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease.

23 Apr 2024

Natural obesity fighters: How coffee, tea, and cocoa combat weight gain

A review in Current Research in Food Science explores how bioactive compounds in coffee, tea, and cocoa combat obesity by inhibiting white adipogenesis and promoting brown adipogenesis and lipolysis.

22 Apr 2024

Young mouse plasma found to reverse aging in older mice

Researchers demonstrate that small extracellular vesicles (sEVs) from young mice plasma can reverse aging effects in older mice by enhancing mitochondrial function and energy metabolism.

22 Apr 2024

Do neighborhood-level disparities in breast cancer–specific survival remain after accounting for individual, tumor, and treatment characteristics?

The role of neighborhood-level disparities in determining shorter breast cancer-specific survival.

22 Apr 2024

Study links air pollution to increased colorectal cancer risk through DNA changes

Researchers reveal how air pollution increases colorectal cancer (CRC) risk through epigenetic changes, using a large-scale study and Mendelian randomization to demonstrate ambient pollution’s impact on CRC mortality and incidence in China.

21 Apr 2024

Animal study suggests early Western diet exposure linked to lasting memory issues

Researchers find that early exposure to a Western diet in rats leads to long-lasting impairments in hippocampus-dependent memory, mediated by disruptions in acetylcholine signaling.

18 Apr 2024

Aging affects immune response and virus dynamics in COVID-19 patients, study finds

A study examining 1031 hospitalized COVID-19 patients found that aging significantly impacts immune responses, viral dynamics, and the nasal microbiome, with older adults experiencing more severe disease symptoms and delayed viral clearance.

18 Apr 2024

UC Riverside nematologist receives NIH award to study parasite-host interactions

To study how parasites evolve to break the defenses of their hosts, the National Institutes of Health has granted UC Riverside nematologist Simon "Niels" Groen a $1.9 million Outstanding Investigator Award.

18 Apr 2024

Research highlights emergence of immune-evasive SARS-CoV-2 variants in immunocompromised patients

New research to be presented at next week's ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April) highlights the risk of new immune-evasive SARS-CoV-2 variants emerging in immunocompromised patients.

18 Apr 2024

Breakthrough research offers hope for patients with persistent Lyme disease symptoms

Tulane University researchers have identified a promising new approach to treating persistent neurological symptoms associated with Lyme disease, offering hope to patients who suffer from long-term effects of the bacterial infection, even after antibiotic treatment.

18 Apr 2024

Siblings with unique gene mutation offer insights into type 1 diabetes treatment

Two siblings who have the only known mutations in a key gene anywhere in the world have helped scientists gain new insights that could help progress the search for new treatments in type 1 diabetes.

18 Apr 2024

ApoA-IV surge after bariatric surgery enhances insulin secretion and energy expenditure

Bariatric surgery has emerged as an effective means of reducing weight in morbidly obese individuals, while also significantly improving diabetes. Currently, laparoscopic sleeve gastrectomy (LSG) and Roux-en-Y gastric bypass (RYGB) are two of the most commonly performed bariatric surgeries.

18 Apr 2024

Phase 2 trial reveals Lixisenatide may reduce motor disability in Parkinson’s patients

A trial of lixisenatide to assess its effects in early Parkinson’s disease.

18 Apr 2024

Receptor News and Research

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Study links acid-reducing drugs to increased risk of migraine

Prostaglandin E2: The culprit behind tumor immune evasion

Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Innovative peptide-based hydrogel therapy for virus prevention

U-M scientists develop new tool to better understand neuronal signaling

New tool hunts for Alzheimer's clues in gut microbiome

Natural obesity fighters: How coffee, tea, and cocoa combat weight gain

Young mouse plasma found to reverse aging in older mice

Do neighborhood-level disparities in breast cancer–specific survival remain after accounting for individual, tumor, and treatment characteristics?

Study links air pollution to increased colorectal cancer risk through DNA changes

Animal study suggests early Western diet exposure linked to lasting memory issues

Aging affects immune response and virus dynamics in COVID-19 patients, study finds

UC Riverside nematologist receives NIH award to study parasite-host interactions

Research highlights emergence of immune-evasive SARS-CoV-2 variants in immunocompromised patients

Breakthrough research offers hope for patients with persistent Lyme disease symptoms

Siblings with unique gene mutation offer insights into type 1 diabetes treatment

ApoA-IV surge after bariatric surgery enhances insulin secretion and energy expenditure

Phase 2 trial reveals Lixisenatide may reduce motor disability in Parkinson’s patients

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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