Renal Failure News and Research RSS Feed - Renal Failure News and Research

Renal failure or kidney failure is where the kidneys fail to function adequately. Renal failure is divided in acute and chronic forms; either form may be due to a large number of other medical problems.
Study provides key insights for effective treatment of individuals with HFpEF

Study provides key insights for effective treatment of individuals with HFpEF

The number of patients hospitalized with HFpEF is now comparable to those with traditional heart failure with a reduced ejection fraction (HFrEF) and is projected to exceed that of HFrEF within the next few years. [More]
Aggressive home blood pressure monitoring may contribute to rise in emergency department visits

Aggressive home blood pressure monitoring may contribute to rise in emergency department visits

Visits to emergency departments for patients with hypertension increased by 64 percent between 2002 and 2012 while hospitalizations for those visits declined by 28 percent. [More]
European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Amgen has announced that the European Commission (EC) has approved a variation to the marketing authorization for Kyprolis® (carfilzomib) to include use in combination with dexamethasone alone for adult patients with multiple myeloma who have received at least one prior therapy. The extended indication marks the second approval for Kyprolis by the EC in less than a year. [More]
First-line nivolumab promising in advanced NSCLC

First-line nivolumab promising in advanced NSCLC

Phase I results published in the Journal of Clinical Oncology suggest that nivolumab, either given alone or alongside platinum-based doublet chemotherapy, could have a role in the first-line treatment of advanced non-small-cell lung cancer. [More]
Study highlights need to improve end-of-life care for all patients with serious illnesses

Study highlights need to improve end-of-life care for all patients with serious illnesses

Historically, efforts to improve end-of-life care have focused primarily on patients with cancer. But few studies have looked at the quality of end-of-life care for patients with other serious illnesses, such as lung, kidney or heart failure or dementia. [More]
Researchers aim to protect kidneys while improving cisplatin's efficacy against cancer

Researchers aim to protect kidneys while improving cisplatin's efficacy against cancer

Cisplatin is a common, powerful chemotherapy agent used for a wide range of cancers such as breast, ovarian and lung, that in a handful of days can also permanently damage or destroy patients' kidneys. [More]
Researchers investigate causes of renal failure using mathematical model

Researchers investigate causes of renal failure using mathematical model

No one can deny that open-heart surgery, where the heart is exposed and the blood is made to bypass it, is one of the most invasive of all medical procedures. Nearly a third of all patients undergoing heart surgery experience kidney failure, yet little is known about why kidney injury occurs or how to prevent it. [More]
Mortality risk proportional to PPM severity in aortic value surgery

Mortality risk proportional to PPM severity in aortic value surgery

Prosthesis-patient mismatch during surgical aortic valve replacement is associated with a perioperative mortality risk that increases with increasing PPM severity, study findings indicate. [More]
Chronic use of antacid drugs may speed up aging of blood vessels

Chronic use of antacid drugs may speed up aging of blood vessels

Chronic use of some drugs for heartburn and gastroesophageal reflux (GERD) speeds up the aging of blood vessels, according to a published paper in Circulation Research, an American Heart Association journal. [More]
Long-term Warfarin use may increase dementia rates in AF patients

Long-term Warfarin use may increase dementia rates in AF patients

A new study of more than 10,000 patients treated long term with the blood thinner, Warfarin, reveals higher rates of dementia for patients with atrial fibrillation versus non-AF patients [More]
Long-term use of herbal remedies may not guarantee safety

Long-term use of herbal remedies may not guarantee safety

Millions of people around the world use herbal health remedies, following a tradition that began millennia ago. Many believe that herbs are safe because they have been used for many years, but researchers from Baylor College of Medicine and Stony Brook University are raising awareness that long-term use of herbal remedies is no guarantee of their safety. The invited commentary appears in EMBO reports. [More]
Entresto drug shows added benefit in symptomatic chronic heart failure

Entresto drug shows added benefit in symptomatic chronic heart failure

The fixed-dose combination of sacubitril and valsartan (trade name: Entresto) has been approved since November 2015 for adults with symptomatic chronic heart failure with reduced pump function (ejection fraction). The German Institute for Quality and Efficiency in Health Care (IQWiG) now examined in an early benefit assessment whether this drug combination offers an added benefit for patients in comparison with the appropriate comparator therapy. [More]
Many kidney transplant patients may benefit from lower-than-standard dose of CNIs

Many kidney transplant patients may benefit from lower-than-standard dose of CNIs

The kidney is the most commonly transplanted organ in the United States, with more than 17,000 transplants performed each year. Following kidney transplant, patients are routinely placed on a regimen of immunosuppressant medications to prevent organ rejection, which often includes calcineurin inhibitors (CNIs) as the backbone medication of this regimen. [More]
Pioneering progress on ADPKD: an interview with Tess Harris

Pioneering progress on ADPKD: an interview with Tess Harris

ADPKD is a chronic, progressive and inherited kidney disease characterized by fluid-filled cysts that develop in the kidneys and other organs. It is the most common inherited kidney disease, and affects millions worldwide. [More]
Scientists trace one of the causes of ischemia renal failure

Scientists trace one of the causes of ischemia renal failure

Every year acute renal failure affects over 13 million people and leads to 1.7 million deaths across the globe. It often develops when an insufficient supply of oxygen reaches the kidneys, a condition called ischemia. [More]
ISHLT issues new list of criteria to determine patient eligibility for heart transplant

ISHLT issues new list of criteria to determine patient eligibility for heart transplant

To determine patient eligibility for heart transplant, the International Society for Heart Lung Transplantation maintains a list of criteria, first issued in 2006, that acts as a guideline for physicians. [More]
CTA scans with reduced amount of contrast medium and radiation dose still provide good image quality

CTA scans with reduced amount of contrast medium and radiation dose still provide good image quality

Wouter Nijhof obtained his PhD at the University of Twente for the research he conducted in collaboration with the Radiology department at the Jeroen Bosch Hospital in 's-Hertogenbosch. [More]
Zurampic (lesinurad) approved to treat high levels of hyperuricemia associated with gout

Zurampic (lesinurad) approved to treat high levels of hyperuricemia associated with gout

The U.S. Food and Drug Administration today approved Zurampic (lesinurad) to treat high levels of uric acid in the blood (hyperuricemia) associated with gout, when used in combination with a xanthine oxidase inhibitor (XOI), a type of drug approved to reduce the production of uric acid in the body. [More]
Shingles vaccine can help protect elderly patients with end-stage renal disease

Shingles vaccine can help protect elderly patients with end-stage renal disease

Elderly patients with end-stage renal disease (ESRD) who received the shingles vaccine were half as likely to develop shingles compared to those who were not vaccinated. The new study from Kaiser Permanente, published in Clinical Infectious Diseases, also found the best protection against shingles was achieved when patients received the vaccination shortly after beginning dialysis. [More]
Egalet, Teva sign agreement to commercialize SPRIX Nasal Spray in Israel, Gaza and the West Bank

Egalet, Teva sign agreement to commercialize SPRIX Nasal Spray in Israel, Gaza and the West Bank

Egalet Corporation, a fully integrated specialty pharmaceutical company focused on developing, manufacturing and commercializing innovative treatments for pain and other conditions, today announced a collaboration agreement with Teva Pharmaceutical Industries Ltd., a leading global pharmaceutical company. [More]
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