Renal Cell Carcinoma

Renal cell carcinoma (RCC, also known as hypernephroma) is a kidney cancer that originates in the lining of the proximal convoluted tubule, the very small tubes in the kidney that filter the blood and remove waste products.

What is Renal Cell Carcinoma?

Renal cell carcinoma, also called hypernephroma, is a cancer of the kidneys that forms in the proximal convoluted tubule. In the UK, it is the eighth most common cancer among adults, affecting 9,300 people every year.

Renal Cell Carcinoma Epidemiology

Renal Cell Carcinoma Symptoms

Renal Cell Carcinoma Diagnosis

Renal Cell Carcinoma Risk Factors

Renal Cell Carcinoma Treatments

Renal Cell Carcinoma Survival Rate

Metastatic Renal Cell Carcinoma

Adjuvant Therapy in Renal Cell Carcinoma

Latest Renal Cell Carcinoma News and Research

NCCN 2024 Annual Conference focuses on practical applications for improving cancer care

The National Comprehensive Cancer Network (NCCN)-;an alliance of leading cancer centers-;hosted more than 1,700 oncology professionals during the NCCN 2024 Annual Conference on April 5-7.

13 Apr 2024

New AI-powered protein mapping tool optimizes cancer therapy

Scientists have developed a new AI tool that maps the function of proteins in a cancerous tumour, enabling clinicians to decide how to target treatment in a more precise way.

13 Feb 2024

AI tool maps protein function in tumors, paving way for personalized cancer treatment

Scientists have developed a new AI tool that maps the function of proteins in a cancerous tumor, enabling clinicians to decide how to target treatment in a more precise way.

9 Feb 2024

Subcutaneous nivolumab revolutionizes renal cell carcinoma care with faster, easier treatment

Subcutaneous injection of the immunotherapy nivolumab (brand name Opdivo) is noninferior to intravenous delivery and dramatically reduces treatment time in patients with renal cell carcinoma, as seen in the results of a large phase 3 clinical trial reported today at the 2024 American Society of Clinical Oncology (ASCO) Genitourinary Cancers Symposium in San Francisco, California.

29 Jan 2024

$2.8M grant targets copper's role in deadly kidney cancer

Copper is an essential trace element required to produce energy in the body and allows humans to live in our atmosphere.

17 Jan 2024

Pazopanib activity confirmed in EWSR1-NFATC2 bone sarcoma

A new case report was published in Oncoscience (Volume 10) on September 20, 2023, entitled, "Activity of pazopanib in EWSR1-NFATC2 translocation-associated bone sarcoma."

12 Jan 2024

Study uses game theory to show low tumor heterogeneity leads to higher aggression

A study by the University of the Basque Country (UPV/EHU) uses game theory to establish that tumors with less cellular heterogeneity are more aggressive.

5 Dec 2023

CMA clarifies cooperation on combination therapies to speed up patient access to vital treatments

The Competition and Markets Authority (CMA) has today issued a statement clarifying that certain types of engagements between competing drug firms working on 'combination therapies' will not be prioritized for investigation - making it easier for drug firms to work together to develop vital treatments for use in the NHS.

17 Nov 2023

HIF-2α inhibitor belzutifan significantly reduces progression of clear cell renal cell carcinoma

Belzutifan significantly reduced the risk of progression of clear cell renal cell carcinoma (ccRCC), the most common type of kidney cancer, in patients previously treated with immune checkpoint inhibitors and anti-angiogenic therapies compared with everolimus in a phase 3 clinical trial.

24 Oct 2023

Dual-action drug produces shows promising results in neuroendocrine tumor trial

A drug that simultaneously strikes cancer cells' growth circuits and pipeline to the bloodstream produced encouraging results in a clinical trial involving patients with advanced neuroendocrine tumors, according to a study led by Dana-Farber Cancer Institute investigators.

22 Oct 2023

Everolimus after surgery may benefit patients with very-high-risk clear cell renal cell carcinoma

A secondary analysis from the SWOG S0931 EVEREST trial has found that in the subgroup of patients with clear-cell renal cell carcinoma (RCC) who were at very-high risk of recurrence, those who were treated with everolimus after surgery had a statistically significant improvement in recurrence-free survival compared to patients getting placebo after surgery.

22 Oct 2023

TTUHSC receives nearly $2.3 million in CPRIT grants to support cancer research

The Cancer Prevention and Research Institute of Texas (CPRIT) recently awarded grants to four researchers from the Texas Tech University Health Sciences Center (TTUHSC).

12 Oct 2023

Stereotactic radiation therapy offers new hope for older adults with inoperable kidney cancer

Older adults diagnosed with kidney tumors that are not suitable for surgery may benefit from targeted, high-dose radiation, a new study from Australian and Dutch researchers suggests.

3 Oct 2023

AI-based tool can assess pathology slides to identify valuable features of clear cell renal cell carcinoma

A team of Dana-Farber researchers has identified a potential new way to assess clinically valuable features of clear cell renal cell carcinoma (ccRCC), a form of kidney cancer, using image processing with deep learning.

20 Sep 2023

Combination of cediranib and lenalidomide does not improve outcomes in advanced thyroid cancer

Results of a multicenter phase II clinical trial led by the University of Chicago Medicine Comprehensive Cancer Center show that adding an immunomodulatory agent to treatment with the targeted tyrosine kinase inhibitor (TKI) cediranib did not make a difference in outcomes for treating patients with an advanced form of thyroid cancer that develops from thyroid follicular cells called differentiated thyroid cancer (DTC).

1 Sep 2023

Associations between alcohol intake, cancer risk, and modifying factors in women: smoking, BMI, and MHT interactions

Researchers examined the association between moderate alcohol intake and specific cancer risks.

21 Aug 2023

Kidney cancer study reveals new findings about MiTF family gene mutations

A new study from clinicians and researchers at the University of Michigan Rogel Cancer Center, U-M Department of Pathology and the Michigan Center for Translational Pathology reveals findings from over 800 clinical assays performed for kidney patients with MiTF family gene mutations.

14 Aug 2023

UCLA researchers confirm mutations that predispose patients to rare kidney cancer syndrome

Researchers at the UCLA Jonsson Comprehensive Cancer Center have confirmed that a large number of genetic variants of unknown significance are in fact verified mutations that predispose patients to a rare hereditary syndrome that increases the risk of kidney cancer.

13 Jul 2023

Fecal transplants safe and effective in treating advanced melanoma, clinical trial shows

In a world-first clinical trial published in the journal Nature Medicine, a multi-center study from Lawson Health Research Institute, the Centre hospitalier de l'Université de Montréal and the Jewish General Hospital (JGH) has found fecal microbiota transplants (FMT) from healthy donors are safe and show promise in improving response to immunotherapy in patients with advanced melanoma.

7 Jul 2023

Single-cell RNA sequencing provides new insights into gastric cancer

A new study led by researchers at The University of Texas MD Anderson Cancer Center provides a deeper understanding of the evolution of the tumor microenvironment during gastric cancer progression.

6 Jul 2023

Renal Cell Carcinoma

Overview

Renal Cell Carcinoma Epidemiology

Renal Cell Carcinoma Symptoms

Renal Cell Carcinoma Diagnosis

Feature Articles

Renal Cell Carcinoma Risk Factors

Renal Cell Carcinoma Treatments

Renal Cell Carcinoma Survival Rate

Metastatic Renal Cell Carcinoma

Adjuvant Therapy in Renal Cell Carcinoma

Latest Renal Cell Carcinoma News and Research

NCCN 2024 Annual Conference focuses on practical applications for improving cancer care

New AI-powered protein mapping tool optimizes cancer therapy

AI tool maps protein function in tumors, paving way for personalized cancer treatment

Subcutaneous nivolumab revolutionizes renal cell carcinoma care with faster, easier treatment

$2.8M grant targets copper's role in deadly kidney cancer

Pazopanib activity confirmed in EWSR1-NFATC2 bone sarcoma

Study uses game theory to show low tumor heterogeneity leads to higher aggression

CMA clarifies cooperation on combination therapies to speed up patient access to vital treatments

HIF-2α inhibitor belzutifan significantly reduces progression of clear cell renal cell carcinoma

Dual-action drug produces shows promising results in neuroendocrine tumor trial

Everolimus after surgery may benefit patients with very-high-risk clear cell renal cell carcinoma

TTUHSC receives nearly $2.3 million in CPRIT grants to support cancer research

Stereotactic radiation therapy offers new hope for older adults with inoperable kidney cancer

AI-based tool can assess pathology slides to identify valuable features of clear cell renal cell carcinoma

Combination of cediranib and lenalidomide does not improve outcomes in advanced thyroid cancer

Associations between alcohol intake, cancer risk, and modifying factors in women: smoking, BMI, and MHT interactions

Kidney cancer study reveals new findings about MiTF family gene mutations

UCLA researchers confirm mutations that predispose patients to rare kidney cancer syndrome

Fecal transplants safe and effective in treating advanced melanoma, clinical trial shows

Single-cell RNA sequencing provides new insights into gastric cancer

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Renal Cell Carcinoma

Overview

Feature Articles

Renal Cell Carcinoma Risk Factors

Renal Cell Carcinoma Treatments

Renal Cell Carcinoma Survival Rate

Metastatic Renal Cell Carcinoma

Adjuvant Therapy in Renal Cell Carcinoma

Latest Renal Cell Carcinoma News and Research

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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