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New studies may offer hope for people with migraine

New studies may offer hope for people with migraine

Two new studies may offer hope for people with migraine. The two studies released today will be presented at the American Academy of Neurology's 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014. [More]
Pfizer reports positive results from two tofacitinib Phase 3 trials for moderate-to-severe plaque psoriasis

Pfizer reports positive results from two tofacitinib Phase 3 trials for moderate-to-severe plaque psoriasis

Pfizer Inc. announced today top-line results from two pivotal Phase 3 trials from the Oral treatment Psoriasis Trials (OPT) Program, OPT Pivotal #1 (A3921078) and OPT Pivotal #2 (A3921079), evaluating the efficacy and safety of tofacitinib, an oral Janus kinase (JAK) inhibitor, the first in a new class of medicines being investigated for the treatment of moderate-to-severe plaque psoriasis. [More]
Pediatric viral respiratory tract infection often complicated by bacterial sinusitis

Pediatric viral respiratory tract infection often complicated by bacterial sinusitis

Nearly 1 in 10 cases of viral upper respiratory tract infections in infants and young children is complicated by acute bacterial sinusitis, often in conjunction with acute otitis media, a longitudinal cohort study has found. [More]
Concordia Healthcare enters into definitive agreement to acquire Donnatal

Concordia Healthcare enters into definitive agreement to acquire Donnatal

Concordia Healthcare Corp., announced today that it has entered into a definitive agreement to acquire Donnatal®, an adjunctive therapy in the treatment of irritable bowel syndrome ("IBS") and acute enterocolitis, from a privately held specialty pharmaceutical company carrying on business as Revive Pharmaceuticals ("Revive Pharmaceuticals"). [More]
L. reuteri Protectis reduces diarrhea, respiratory tract infections in healthy children

L. reuteri Protectis reduces diarrhea, respiratory tract infections in healthy children

Healthy children attending day-care centres have a significantly lower risk of getting diarrhoea or respiratory tract infections when given a daily supplement of Lactobacillus reuteri Protectis, a study in 336 children shows. "Our study confirms earlier published data in proving that preventive use of L. reuteri Protectis in healthy children reduces diarrhoeic episodes. [More]
Atopix presents positive results of Phase IIb asthma study at AAAAI meeting

Atopix presents positive results of Phase IIb asthma study at AAAAI meeting

Atopix Therapeutics Ltd ("Atopix"), a biopharmaceutical company developing innovative CRTH2 antagonists for allergic disease, announced the results of a Phase IIb asthma study with their lead compound OC459 at the American Academy of Allergy, Asthma and Immunology (AAAAI) Annual Meeting , San Diego, California, USA on March 1st. [More]
FDA approves sNDA to include radiographic data updating label of Pfizer XELJANZ for treatment of RA

FDA approves sNDA to include radiographic data updating label of Pfizer XELJANZ for treatment of RA

Pfizer Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved a supplemental New Drug Application (sNDA) to update the current label of XELJANZ® (tofacitinib citrate) 5 mg tablets to include radiographic data from two Phase 3 studies, ORAL Scan (A3921044) and ORAL Start. [More]
Antibiotics prescribed for children who have URIs does not prevent complications

Antibiotics prescribed for children who have URIs does not prevent complications

Antibiotics are often prescribed for young children who have upper respiratory tract infections (URIs) in order to prevent complications, such as ear infections and pneumonia, however, a new evidence review in The Cochrane Library found no evidence to support this practice. [More]

Air pollution puts pressure on primary care

Research in Hong Kong shows that air pollution concentrations are significantly associated with the number of consultations for upper respiratory tract infections (URTIs), contributing to the burden on primary care services. [More]

Infection contributes to higher risk of stroke death among blacks

Infection is a stronger trigger of stroke death in African- Americans than in whites, a University of Michigan study shows. [More]
NICE approves MabThera for treating severe forms of GPA and MPA

NICE approves MabThera for treating severe forms of GPA and MPA

Today the National Institute for Health and Care Excellence has approved the use of MabThera for two potentially life-threatening auto-immune diseases, GPA and MPA, which result in the inflammation and damage of small blood vessels and frequently involve multiple organs. The two diseases affect over 13,000 people in the UK and are characterised by the breaking down of specific areas of tissue in the body that, if not treated, can lead to organ damage, organ failure and even death. [More]
First antigen test for human bocavirus type 1 now available on ArcDia's mariPOC test platform

First antigen test for human bocavirus type 1 now available on ArcDia's mariPOC test platform

ArcDia Ltd. ArcDia International Ltd today announced that the first antigen test for human bocavirus type 1 is now commercially available on ArcDia's mariPOC test platform. [More]
Cord blood vitamin D linked to pediatric RTI risk

Cord blood vitamin D linked to pediatric RTI risk

South Korean researchers say that encouraging pregnant women to spend more time outdoors or to increase their vitamin D supplementation may reduce the number of respiratory tract infections in their infants. [More]
Perinatal probiotic supplements do not prevent childhood asthma

Perinatal probiotic supplements do not prevent childhood asthma

There is insufficient evidence to support the use of probiotic supplements during pregnancy or infancy to prevent the development of asthma in infants, Canadian researchers report. [More]
Streptococcus biofilms persist on objects, surfaces in daycare center for longer periods after cleaning

Streptococcus biofilms persist on objects, surfaces in daycare center for longer periods after cleaning

​Numerous scientific studies have concluded that two common bacteria that cause colds, ear infections, strep throat and more serious infections cannot live for long outside the human body. [More]

Duration of common pediatric respiratory infections estimated

An international research team has systematically reviewed the literature to formulate up-to-date estimates of the duration of common childhood respiratory tract infections. [More]

Interactive booklet boosts parents’ RTI confidence

An interactive booklet given to parents in primary care can help them to be more knowledgeable and feel more confident about when and when not to consult a doctor for their child’s respiratory tract infections. [More]
Maternal weight issues spell wheezing trouble for children

Maternal weight issues spell wheezing trouble for children

High maternal weight and gestational weight gain are independently associated with an increased risk for wheezing in preschool age children, a Dutch study has found. [More]

Paracetamol, ibuprofen or combination of both provide no advantage for respiratory tract infections

Questions have been raised about the advice given to patients with a cold and sore throat, in research published in the British Medical Journal. [More]

Influenza vaccination linked with reduced risk of adverse cardiovascular events

Receiving an influenza vaccination was associated with a lower risk of major adverse cardiovascular events such as heart failure or hospitalization for heart attack, with the greatest treatment effect seen among patients with recent acute coronary syndrome (ACS; such as heart attack or unstable angina), according to a meta-analysis published in the October 23/30 issue of JAMA. [More]