Retinal Degeneration News and Research

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Retinal tissue may degenerate for a number of reasons. Among them are: artery or vein occlusion, diabetic retinopathy, R.L.F./R.O.P. or disease (usually hereditary). Retinitis pigmentosa, retinoschisis, lattic degeneration, and macular degeneration are characterized by progressive types of retinal degeneration.

Roundworms shed light on vision loss in a rare human genetic disorder

In this interview, News-Medical speaks to Xinxing Zhang, a postdoctoral research fellow at the University of Michigan, about his research investigating vision loss in Bardet-Biedl syndrome.

4 Jul 2022

Single-cell-resolution map of retinal pigment epithelium could help develop precise therapies for degenerative diseases

Researchers have identified distinct differences among the cells comprising a tissue in the retina that is vital to human visual perception.

6 May 2022

Fecal microbiota transplant can reverse hallmarks of aging in mice

In the search for eternal youth, poo transplants may seem like an unlikely way to reverse the aging process.

5 May 2022

Study evaluates the ocular tropism and the possible ocular transmission of SARS-CoV-2 in animal models

Researchers demonstrated ocular tropism of SARS-CoV-2 through neuronal invasion in transgenic mice with hACE2 expression.

20 Apr 2022

Scientists shine new light on the complexity of vitamin B12 diseases

A team of researchers at Baylor College of Medicine and collaborating institutions has shed new light into the complexity of vitamin B12 diseases.

10 Jan 2022

WVU receives funding from National Eye Institute for retinal degeneration research

Inherited retinal degeneration can make even the most mundane tasks-;like cooking, driving and walking down the sidewalk-;difficult or impossible, and it can't be cured.

6 Jan 2022

Gene therapy and diabetes drug may be treatments for late-onset retinal degeneration

Scientists have discovered that gene therapy and the diabetes drug metformin may be potential treatments for late-onset retinal degeneration (L-ORD), a rare, blinding eye disease.

9 Dec 2021

HyVIS project to develop bionic synapses for retinal prostheses

HyVIS, the European project coordinated by the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology), is about to start.

3 Dec 2021

New technology streamlines the development of gene therapy for genetic blinding disorders

A novel computational platform developed by researchers from the University of Pittsburgh School of Medicine identifies top-performing viral vectors that could deliver gene therapies to the retina with maximum efficiency and precision.

19 Oct 2021

New study finds SARS-CoV-2 causes retinal infection

Can coronavirus disease 2019 (COVID-19) affect the eye? New research suggests the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can enter the eye and infect photoreceptor and retinal ganglion cells. In addition, SARS-CoV-2 infection increases the expression of several inflammatory genes, including the cytokine interleukin 33 (IL33), which is linked to COVID-19 disease and retinal degeneration.

13 Oct 2021

Nanoscope presents optical gene delivery, OCT-guided electrophysiology platforms at ARVO annual meeting

Nanoscope Technologies LLC, a biotechnology company developing gene therapies for treatment of retinal diseases, is featuring multiple scientific presentations highlighting its groundbreaking research on optical gene delivery for vision restoration and OCT-guided electrophysiology platforms for characterization of retinal degeneration and assessment of efficacy of cell-gene therapy at the 2021 ARVO annual (virtual) meeting, May 1-7.

5 May 2021

Researcher uses alternative approach to find genetic drivers of rare eye disease

An analysis of thousands of genomes from people with and without the rare eye disease known as MacTel has turned up more than a dozen gene variants that are likely causing the condition to develop and worsen for a significant share of patients.

23 Mar 2021

Research shows how mutation linked with CLN3-Batten disease could lead to vision loss

Progressive vision loss, and eventually blindness, are the hallmarks of juvenile neuronal ceroid lipofuscinosis (JNCL) or CLN3-Batten disease.

8 Feb 2021

Novel device may help restore total eye function

An international consortium of researchers is developing a new method to bring eyes back to life from deceased body donors for clinical research purposes.

18 Dec 2020

Researchers use new imaging technique to produce digital reconstruction of eye tissues

A new study by scientists at the University of Southampton has made a breakthrough that could help the search for treatments against age related sight loss.

2 Dec 2020

Study uncovers a promising therapeutic target for retinal dystrophies

A team of LSU Health New Orleans researchers reports for the first time that deleting one of the inhibitors of the RPE65 gene in a mouse model that carries a human disease mutation prevents degeneration of cone photoreceptors that are used for daytime high-resolution color vision.

1 Dec 2020

FAU researchers receive NIH funding to analyze stem cell activation

Researchers from Florida Atlantic University's Schmidt College of Medicine hope to conquer a major limitation in the ability for scientists to engineer tissues for regenerative therapies for age-related and degenerative diseases.

14 Oct 2020

Neurobiologists decode central mechanism of degenerative processes in brains of mouse models

Heidelberg neurobiologists decode central mechanism of degenerative processes in the brains of mouse models and develop new principle for therapeutic agents

9 Oct 2020

First pathoconnectome shows how eye disease alters retinal circuitry

Scientists from the John A. Moran Eye Center at the University of Utah have achieved another first in the field of connectomics, which studies the synaptic connections between neurons.

30 Sep 2020

Novel mechanism that may confer protection against glaucoma identified

A team of researchers from LSU Health New Orleans Neuroscience Center of Excellence and the University of Copenhagen provides the first evidence that patients with ocular hypertension may exhibit superior antioxidant protection that promotes resistance to the elevated intraocular pressure associated with glaucoma.

17 Sep 2020