Rhabdomyolysis News and Research

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Rhabdomyolysis (often shortened to simply "rhabdo") is the rapid breakdown (''lysis'') of skeletal muscle (''rhabdomyo'') due to injury to muscle tissue.

The effects and mechanisms of SARS-CoV-2 on the nervous system

Researchers reviewed the neurologic manifestations associated with SARS-CoV-2.

30 Jun 2022

The autoantibody profile in COVID-19 patients with MIS-C

A new study assessed the presence of autoantibodies against autoantigens associated with known autoimmune diseases in patients with COVID-19.

10 Nov 2021

UPMC expert finds successful treatment for rare diseases diagnosed by newborn screenings

1It was a nagging mystery: A rare-disease expert at UPMC Children's Hospital of Pittsburgh had found a successful treatment for two of the deadliest symptoms of one of the more common classes of rare diseases diagnosed by newborn screenings, but one symptom--painful episodes of muscle breakdown that land victims in intensive care--persisted.

29 Jun 2021

Low potassium levels in COVID-19 disease

Now a new study by an Italian team of researchers published in June 2020 on the preprint server medRxiv reports that potassium levels are often low in COVID-19 disease, mostly due to the urinary loss of potassium.

17 Jun 2020

New computer model predicts suicide risk

Suicide is now the second most common cause of death among American youth. Fatal suicides rose 30 percent between 2000 and 2016, and 2016 alone saw 1.3 million nonfatal suicide attempts.

25 Apr 2020

Researchers visualize first structure of key enzyme that helps make triglycerides

The first structure of a lipin enzyme, which carries out an important step in the production of triglycerides, the main reservoir for long-term energy storage, will help scientists to better understand how lipins regulate the production of triglycerides.

11 Mar 2020

Rushing into intense exercise after a break can cause “rhabdo”, potentially leading to kidney injury

New evidence is coming to light warning people from rushing too quickly into intense exercise.

27 Jan 2020

Alzheimer's drug associated with two-fold higher risk of hospitalization for rhabdomyolysis

A drug commonly used to manage symptoms of Alzheimer disease and other dementias -- donepezil -- is associated with a two-fold higher risk of hospital admission for rhabdomyolysis, a painful condition of muscle breakdown, compared with several other cholinesterase inhibitors, found a study in CMAJ.

16 Sep 2019

Burns and electrocution risk increased with generic phone chargers, says review

A recent case report in the Annals of Emergency Medicine revealed the potential risk of serious burns and electrocution with the use of generic phone chargers compared to branded ones, as shown by several analyses.

26 Jul 2019

Researchers identify previously unknown autoimmune disease involving muscle pain, weakness

A previously unknown autoimmune muscle disease involving sudden onset of debilitating muscle pain and weakness has been identified by researchers at Washington University School of Medicine in St. Louis.

3 Jun 2019

Statins associated with low risk of side effects

The cholesterol-lowering drugs called statins have demonstrated substantial benefits in reducing the risk of heart attacks and strokes caused by blood clots (ischemic strokes) in at-risk patients.

10 Dec 2018

Study reveals safety, efficacy of brexpiprazole for schizophrenia patients with severe psychotic symptoms

Otsuka Pharmaceutical Co., Ltd. and H. Lundbeck A/S announced study results on the safety and efficacy of brexpiprazole in the treatment of patients with schizophrenia experiencing severe psychotic symptoms during an acute episode. The data will be presented at the upcoming Psych Congress, held in Orlando from October 25-28, 2018.

26 Oct 2018

Combination of Opdivo and Yervoy shows four-year survival benefits in patients with advanced melanoma

Bristol-Myers Squibb Company today announced four-year data from the Phase 3 CheckMate -067 clinical trial - the longest follow-up to date - which continues to demonstrate durable, long-term survival benefits with the first-line combination of Opdivo (nivolumab) and Yervoy (ipilimumab), versus Yervoy alone, in patients with advanced melanoma.

22 Oct 2018

Novartis' new drug combination receives positive CHMP opinion for treating stage III BRAF mutant melanoma

Novartis today announced the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted a positive opinion recommending approval of Tafinlar® in combination with Mekinist® for the adjuvant treatment of adult patients with stage III melanoma with a BRAF V600 mutation, following complete resection.

27 Jul 2018

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Bristol-Myers Squibb Company today announced patient-reported outcomes data from the Phase 3 CheckMate -214 trial in intermediate- and poor-risk patients with advanced renal cell carcinoma treated with the Immuno-Oncology combination Opdivo plus low-dose Yervoy versus sunitinib over a two-year follow-up period.

1 Jun 2018

Testing Service Members for Heat Related Illnesses Before Combat

It is common to think that combat deployment is the most dangerous part of being a warfighter, and in many ways this is correct. However, warfighters need to do many things before they are cleared to deploy to combat zones. Most cases of exertional heat illness (EHI) reported in the U.S. military occur during non-combat activities, such as training regimens, ruck marches, and operational exercises.

From Physitemp Instruments LLC 6 Sep 2017

Tiny 'submarines' could help treat stomach diseases with acid-sensitive drugs

Tiny “submarines” that speed independently through the stomach, use gastric acid for fuel (while rapidly neutralizing it), and release their cargo precisely at the desired pH: Though it may sound like science fiction, this is a new method for treating stomach diseases with acid-sensitive drugs introduced by scientists in the journal Angewandte Chemie.

24 Jan 2017

Sickle cell trait linked to increased risk of rhabdomyolysis among African American Soldiers

A new study published Aug. 4 in the New England Journal of Medicine indicates that among African American U.S. Army Soldiers, sickle cell trait is not associated with an increase in mortality, but is associated with a modest increase in the risk of exertional rhabdomyolysis.

4 Aug 2016

Sickle cell trait may not increase mortality risk

People who carry a gene for sickle cell disease do not appear to be at an increased risk of premature death, according to a study by researchers from Stanford University School of Medicine.