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Reviving reservoirs: new findings shake up HIV treatment understanding

Researchers provide insight into the interaction between T lymphocytes and persisting reservoirs of HIV, with repercussions for harnessing effective, long-lasting responses to HIV eradication.

14 Sep 2023

New Omicron subvariant BA.2.86: A master of immune escape but not taking over yet

Researchers have isolated a new SARS-CoV-2 Omicron subvariant, BA.2.86, revealing its ability to escape neutralizing antibodies five-fold greater than its ancestor strain. Despite its enhanced immune evasion capabilities, BA.2.86 has not shown a significant difference in spread compared to other current variants.

13 Sep 2023

Early sepsis detection: molecular immune markers show limited impact in screening tools

Researchers evaluated the additional predictive value of molecular immune markers with the Predict Sepsis screening tools developed previously by the same research team.

13 Sep 2023

How COVID-19 targets the pancreas revealed

The study uncovers the role of the PLAC8 protein in making the human pancreas vulnerable to SARS-CoV-2 infection, leading to pancreatic injury and complications in severe COVID-19 cases. The findings open up new avenues for understanding how the virus affects multiple organ systems and offer a potential target for future treatments.

12 Sep 2023

CDC advises healthcare providers on new tools to combat RSV

The CDC predicts increased activity of Respiratory Syncytial Virus (RSV) for the upcoming winter season, urging clinicians to implement new prevention tools like nirsevimab and FDA-approved vaccines for vulnerable populations. The advisory comes as RSV activity shows a changing pattern, affecting infants, children, and adults, and causing thousands of hospitalizations annually.

10 Sep 2023

Unlocking the secret drivers of deadly pancreatic cancer: New target offers hope for treatment

Researchers identify a super-enhancer-regulated RNA-binding protein cascade that drives the growth of pancreatic ductal adenocarcinoma, a deadly form of pancreatic cancer. The discovery offers a promising new avenue for targeted therapy, potentially sidestepping severe side effects associated with other treatments.

10 Sep 2023

Vaccination amps up antibody response and cuts down COVID severity, UK study shows

UK study reveals COVID-19 vaccination effectively boosts anti-S antibody levels and reduces symptom severity post-infection, irrespective of the viral variant involved. High antibody levels are linked to quicker viral clearance, suggesting reduced transmission risk.

10 Sep 2023

The role of exercise-induced hormone irisin in amyloid beta reduction

Researchers explored the biological mechanisms by which exercise-induced irisin attenuates amyloid-beta pathology in Alzheimer’s disease.

8 Sep 2023

Chronic inflammation's influence on TP53 mutations in leukemia evolution explored in new study

Researchers performed a multi-omics evaluation of HSPCs obtained from individuals with myeloproliferative neoplasms transforming to TP53-related secondary forms of acute myeloid leukemia.

7 Sep 2023

Specialized astrocyte subpopulation discovery sheds light on brain health and treatment avenues

In a recent study published in Nature, researchers investigated whether glutamatergic gliotransmission was mediated by specialized astrocytes in the central nervous system.

7 Sep 2023

Study reveals heart failure insights at single-cell level

Researchers examined the cell-intrinsic effects of hematopoietic stem cells with somatic mutations in circulating cells from heart failure patients.

6 Sep 2023

Using ChatGPT to address vaccine hesitancy: a promising tool for guiding users to scientific information?

Researchers assessed ChatGPT's ability to address the 50 most common misconceptions about vaccine safety.

6 Sep 2023

Monovalent vaccine outperforms bivalent in fighting new Omicron variants

New U.S. study finds mRNA-1273.815, a monovalent vaccine targeting the Omicron XBB.1.5 variant, generates higher neutralizing antibody titers compared to its bivalent counterpart. The study supports updating to an XBB.1.5-based monovalent vaccine for the 2023-24 campaign to combat emerging variants.

5 Sep 2023

How SARS-CoV-2 hijacks Fragile X proteins to fuel infection: New clues in COVID-19 and genetic disorders

Study explores the interaction between SARS-CoV-2's non-structural protein 3 (NSP3) and proteins related to Fragile X mental retardation (FMRPs), shedding light on COVID-19 pathophysiology. The research suggests that the virus exploits these host cell proteins for effective infection and possibly interferes with antiviral defense mechanisms, offering new insights into the genetic basis of Fragile X syndrome.

5 Sep 2023

SARS-CoV-2 Eris variant spreads faster and dodges immunity

Study investigates the characteristics of the EG.5.1 "Eris" variant of SARS-CoV-2, finding it more transmissible among hamsters and slightly better at evading immunity compared to the XBB.1.5 variant. The results suggest that these properties could be driving the variant's increasing prevalence in human populations.

5 Sep 2023

Gut microbes play a starring role in insulin resistance, opening doors for new diabetes treatments

The study reveals a strong association between gut microbial carbohydrate metabolism and insulin resistance, pointing to gut microbes as a key player in metabolic syndrome and type 2 diabetes. Targeting these microbial activities could offer a new therapeutic pathway for improving insulin resistance and overall metabolic health.

4 Sep 2023

Ribonucleic Acid News and Research

Reviving reservoirs: new findings shake up HIV treatment understanding

New Omicron subvariant BA.2.86: A master of immune escape but not taking over yet

Early sepsis detection: molecular immune markers show limited impact in screening tools

How COVID-19 targets the pancreas revealed

CDC advises healthcare providers on new tools to combat RSV

Unlocking the secret drivers of deadly pancreatic cancer: New target offers hope for treatment

Vaccination amps up antibody response and cuts down COVID severity, UK study shows

The role of exercise-induced hormone irisin in amyloid beta reduction

Chronic inflammation's influence on TP53 mutations in leukemia evolution explored in new study

Specialized astrocyte subpopulation discovery sheds light on brain health and treatment avenues

Study reveals heart failure insights at single-cell level

Using ChatGPT to address vaccine hesitancy: a promising tool for guiding users to scientific information?

Monovalent vaccine outperforms bivalent in fighting new Omicron variants

How SARS-CoV-2 hijacks Fragile X proteins to fuel infection: New clues in COVID-19 and genetic disorders

SARS-CoV-2 Eris variant spreads faster and dodges immunity

Gut microbes play a starring role in insulin resistance, opening doors for new diabetes treatments

Study characterizes SARS-CoV-2 subvariants to inform development of next-generation COVID-19 vaccines

Study investigates the pathophysiological mechanisms of PASC after COVID-19

Study explores the role of sex on mRNA and protein levels and its genetic regulation in brain

Wild boars and Hepatitis E: Whats the zoonotic risk?

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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