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Rotavirus is the most common cause of severe diarrhea among children, resulting in the hospitalization of approximately 55,000 children each year in the United States and the death of over 600,000 children annually worldwide. The incubation period for rotavirus disease is approximately 2 days. The disease is characterized by vomiting and watery diarrhea for 3 - 8 days, and fever and abdominal pain occur frequently. Immunity after infection is incomplete, but repeat infections tend to be less severe than the original infection.
Vaccinations could have significant economic value

Vaccinations could have significant economic value

Vaccinations, long recognized as an excellent investment that saves lives and prevents illness, could have significant economic value that far exceeds their original cost, a new study from researchers at the Johns Hopkins Bloomberg School of Public Health has found. [More]
New research sheds light on how gut damage can cause malnutrition, oral vaccine failure

New research sheds light on how gut damage can cause malnutrition, oral vaccine failure

It has been estimated that if every nutritional measure known to be helpful were applied to every child in the world, global malnutrition would be decreased by only a third. New research from the University of Virginia School of Medicine, the University of Vermont and the International Centre for Diarrhoeal Disease Research in Bangladesh sheds light on why: Damage to the gut from infection explains why food alone is not a solution to malnutrition. [More]
CureVac raises €100M to enable rapid expansion of mRNA development platform, clinical-stage pipeline

CureVac raises €100M to enable rapid expansion of mRNA development platform, clinical-stage pipeline

CureVac, a clinical-stage biopharmaceutical company pioneering the field of mRNA-based technology, today announces that it has raised about $110 million (€100 million) to enable accelerated expansion of its industry-leading messenger RNA (mRNA) development platform and clinical-stage pipeline. [More]
Environmental and lifestyle factors contribute to development of celiac disease

Environmental and lifestyle factors contribute to development of celiac disease

Celiac disease incidence has increased among Swedish children between 2 to 15 years. The significant escalation in celiac disease can be associated with planned caesarean sections, urinary tract infections during pregnancy, season of birth and being born in south Sweden. [More]
New test capable of detecting all viruses that affect people and animals

New test capable of detecting all viruses that affect people and animals

A new, super-sensitive test has been developed that can detect virtually any virus that causes illness in humans and animals, according to researchers at Washington University School of Medicine in St. Louis. [More]
New test identifies viruses that infect people and animals

New test identifies viruses that infect people and animals

A new test detects virtually any virus that infects people and animals, according to research at Washington University School of Medicine in St. Louis, where the technology was developed. [More]
Pneumococcal and rotavirus vaccines lead to rapid reduction in pediatric hospital burden

Pneumococcal and rotavirus vaccines lead to rapid reduction in pediatric hospital burden

Researchers show that the introduction of both pneumococcal conjugate vaccines (PCVs) and rotavirus vaccines (RVs) led to the rapid and dramatic reduction in hospital burden of both winter diarrhea and respiratory infections within <5 years post introduction of the vaccines. [More]
CureVac announces official launch of U.S. operations in Cambridge, MA

CureVac announces official launch of U.S. operations in Cambridge, MA

CureVac, a clinical-stage biopharmaceutical company pioneering the field of mRNA-based technology, today announced the official launch of its U.S. operations in Cambridge, MA, as the company advances the development of its proprietary mRNA platform technology and multiple, clinical-stage mRNA therapeutics and vaccines. [More]
Researchers uncover new mechanism that innate immune system uses to curb viral infections

Researchers uncover new mechanism that innate immune system uses to curb viral infections

An innovative mechanism that the innate immune system uses to control viral infections has been uncovered by researchers at the University Medical Centers in Mainz and Freiburg. Central to this is the discovery that two different but related elements of the immune system can act together in concert to fight, for example, rotavirus infections. [More]
Acute gastroenteritis hospitalization rates among young U.S. children decline following use of rotavirus vaccine

Acute gastroenteritis hospitalization rates among young U.S. children decline following use of rotavirus vaccine

Following implementation of rotavirus vaccination in 2006, all-cause acute gastroenteritis hospitalization rates among U.S. children younger than 5 years of age declined by 31 percent - 55 percent in each of the post-vaccine years from 2008 through 2012, according to a study in the June 9 issue of JAMA. [More]
New microneedle patch simplifies measles vaccination

New microneedle patch simplifies measles vaccination

A new microneedle patch being developed by the Georgia Institute of Technology and the Centers for Disease Control and Prevention (CDC) could make it easier to vaccinate people against measles and other vaccine-preventable diseases. [More]
Researchers team up to study stomach flu

Researchers team up to study stomach flu

Rice University bioengineers are teaming with colleagues from Baylor College of Medicine and MD Anderson Cancer Center to apply the latest techniques in tissue engineering toward the study of one of the most common and deadly human illnesses -- the stomach flu. [More]
Efficacy of ebola vaccine to be assessed in large-scale clinical trial

Efficacy of ebola vaccine to be assessed in large-scale clinical trial

GlaxoSmithKline (GSK) announced today that they will soon be commencing the first large-scale clinical trial to assess the efficacy of an experimental ebola vaccine. [More]
Zylast selected as a winner of USAID Fighting Ebola Grand Challenge

Zylast selected as a winner of USAID Fighting Ebola Grand Challenge

Zylast products have been selected as one of only three initial winners of the USAID Fighting Ebola Grand Challenge. The announcement, made from the White House, introduces Zylast as a solution to "help healthcare workers on the front lines provide better care and stop the spread of Ebola." [More]
Bacterial protein flagellin can prevent and cure rotavirus infection

Bacterial protein flagellin can prevent and cure rotavirus infection

Activation of the innate immune system with the bacterial protein flagellin could prevent and cure rotavirus infection, which is among the most common causes of severe diarrhea, says a Georgia State University research team that described the method as a novel means to prevent and treat viral infection. [More]
Four out of ten children in Burkina Faso genetically resistant to virus strains

Four out of ten children in Burkina Faso genetically resistant to virus strains

Every year rotavirus causes half a million diarrhoea-related deaths amongst children in developing countries. Existing vaccines provide poor protection. The reason could be a widespread genetic resistance amongst children, according to virologists at Linköping University. [More]
Sanitation programme in India increases latrine coverage, not health

Sanitation programme in India increases latrine coverage, not health

A sanitation programme currently being widely implemented in low-income communities in India significantly increases latrine coverage but does not actually improve health, a study involving 100 rural villages, published in The Lancet Global Health has found. [More]
UPM researchers find way to enhance detection of rotavirus

UPM researchers find way to enhance detection of rotavirus

Researchers at the Universidad Politécnica de Madrid have found a way to enhance detection capacity of small concentrations of rotavirus. All this thanks to a new way to assess the biosensing response applied to an interferometric device. [More]
Gastroenterologist hopes to achieve healthy growth and development in children around the world

Gastroenterologist hopes to achieve healthy growth and development in children around the world

Why is it harder for kids in low- and middle-income countries to grow as well as kids in wealthy countries? Food security, or access to good nutrition, remains a major challenge. The issue is not just food supply but poor sanitation - a problem exacerbated by local infrastructure and cultural mores. [More]
High uptake of US infant vaccination in 2013

High uptake of US infant vaccination in 2013

The recently published National Immunization Survey (NIS) conducted by the CDC, shows that the majority of infants in the US were vaccinated against potentially serious diseases in 2013. Fewer than 1% of children were unvaccinated in 2013. [More]
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