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Rotavirus is the most common cause of severe diarrhea among children, resulting in the hospitalization of approximately 55,000 children each year in the United States and the death of over 600,000 children annually worldwide. The incubation period for rotavirus disease is approximately 2 days. The disease is characterized by vomiting and watery diarrhea for 3 - 8 days, and fever and abdominal pain occur frequently. Immunity after infection is incomplete, but repeat infections tend to be less severe than the original infection.
LDL cholesterol blood level declines found to have abruptly ended in 2008

LDL cholesterol blood level declines found to have abruptly ended in 2008

Decades of declines in LDL cholesterol blood levels, a key marker of death risk from heart disease, abruptly ended in 2008, and may have stalled since, according to a multi-year, national study published in PLOS ONE. [More]
India's DBT, Bharat Biotech announce positive Phase III clinical trial results of rotavirus vaccine

India's DBT, Bharat Biotech announce positive Phase III clinical trial results of rotavirus vaccine

The Government of India's Department of Biotechnology and Bharat Biotech announced positive results from a Phase III clinical trial of a rotavirus vaccine developed and manufactured in India. [More]
New study provides clear picture of the impact and causes of diarrheal diseases

New study provides clear picture of the impact and causes of diarrheal diseases

A new international study published today in The Lancet provides the clearest picture yet of the impact and most common causes of diarrheal diseases, the second leading killer of young children globally, after pneumonia. [More]
New VLP vaccine candidate produced for H7N9 virus

New VLP vaccine candidate produced for H7N9 virus

Medicago Inc., a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles, today announced that it has successfully produced a new VLP vaccine candidate for the H7N9 virus that is responsible for the current influenza outbreak in China. [More]
Opinion pieces address Global Vaccine Summit

Opinion pieces address Global Vaccine Summit

Project Syndicate last week published two opinion pieces addressing the Global Vaccine Summit, held in Abu Dhabi from April 24-25, which was hosted by His Highness General Sheikh Mohamed bin Zayed bin Sultan Al Nahyan, Crown Prince of Abu Dhabi, in partnership with U.N. Secretary-General Ban Ki-moon and Bill Gates, co-chair of the Bill & Melinda Gates Foundation. [More]

Blog posts address goal of universal immunization

World Immunization Week (April 21-28) aims to raise awareness that immunizations avert two to three million deaths annually, but an estimated 22 million infants are not fully immunized with routine vaccines. [More]
Global experts highlight strategies to immunize more children

Global experts highlight strategies to immunize more children

In advance of World Immunization Week, global experts are highlighting strategies to further advance progress on the Global Vaccine Action Plan that was endorsed by the World Health Assembly, 2012. [More]

WHO, UNICEF launch new Global Action Plan to save children from pneumonia and diarrhoea

A new Global Action Plan launched today by the WHO and UNICEF has the potential to save up to 2 million children every year from deaths caused by pneumonia and diarrhoea, some of the leading killers of children under five globally. [More]
New national study examines marijuana use and prescription drug misuse

New national study examines marijuana use and prescription drug misuse

Individuals who use marijuana recreationally are more likely to misuse other drugs, including pain-controlling, but potentially addictive narcotics, sedatives and other prescription medications, than individuals who do not use marijuana, according to a new national study issued today by Quest Diagnostics, the world's leading provider of diagnostic information services. [More]
New study shows varicella vaccine neutralizes chicken pox

New study shows varicella vaccine neutralizes chicken pox

Chicken pox, the childhood affliction of earlier generations, has been largely neutralized by the varicella vaccine, according to a new study by the Kaiser Permanente Vaccine Study Center, which appears in the current online issue of Pediatrics. [More]

Global efforts to address malnutrition should factor in immunization

"On Red Nose Day, we are reminded of the famine in Ethiopia that triggered the first Comic Relief, over 25 years ago," and "as we reflect, we now know that the link between malnutrition and infectious disease makes for a particularly vicious circle," Seth Berkley, CEO of the GAVI Alliance, writes in an opinion piece in the Guardian's "Global Development Professionals Network." [More]
Vaccine prices and availability: an interview with Kate Elder, Vaccines Policy Advisor for Médecins Sans Frontières's Access Campaign

Vaccine prices and availability: an interview with Kate Elder, Vaccines Policy Advisor for Médecins Sans Frontières's Access Campaign

One of the key reasons why children are missed by immunization programs, particularly in developing countries where Médecins Sans Frontières (MSF) works, is that the products that we currently have in their present formulation are not well-suited to the places that have the most un-immunized children. These are the most challenging contexts to work in. [More]
Rotavirus vaccination in children impacts on adults

Rotavirus vaccination in children impacts on adults

Vaccinating children against rotavirus should be encouraged, say researchers, following findings that the prevalence of the disease has recently halved among unvaccinated adults in the USA. [More]
High vaccine prices ignored by ‘Decade of Vaccines’ blueprint

High vaccine prices ignored by ‘Decade of Vaccines’ blueprint

Governments meeting at the World Health Organization’s Executive Board (WHO EB) this week must seize the opportunity to improve serious shortcomings in the document that will drive the global community’s vaccines response in the next few years. If they fail to do so, key reasons why children continue to be missed by immunisation programmes will be left unaddressed. [More]
Pediatric rotavirus vaccination indirectly protects unvaccinated adults

Pediatric rotavirus vaccination indirectly protects unvaccinated adults

Pediatric rotavirus vaccination also indirectly protects unvaccinated adults from the highly contagious cause of severe diarrhea and vomiting, suggests a new study published in Clinical Infectious Diseases and available online. [More]

Indian company plans to make lower-cost injectable polio vaccine

Serum Institute of India Ltd., the world's largest vaccine manufacturer, plans to "slash the price of polio immunization and introduce shots for diarrhea and pneumonia, undercutting Pfizer Inc. and GlaxoSmithKline Plc.," Bloomberg Businessweek reports. [More]
Towards imaging biological processes in action at the atomic level

Towards imaging biological processes in action at the atomic level

If the key to winning battles is knowing both your enemy and yourself, then scientists are now well on their way toward becoming the Sun Tzus of medicine by taking a giant step toward a priceless advantage - the ability to see the soldiers in action on the battlefield. [More]

New technique to directly image biological structures at atomic levels

Investigators at the Virginia Tech Carilion Research Institute have invented a way to directly image biological structures at their most fundamental level and in their natural habitats. The technique is a major advancement toward the ultimate goal of imaging biological processes in action at the atomic level. [More]

Health workers face 'severe logistical challenges' to vaccinating Maasai tribes in Tanzania

Chris Endean of the GAVI Alliance writes ahead of the GAVI Partners Forum in a CNN opinion piece about efforts to vaccinate members of the Maasai tribes in Tanzania's Arusha National Park. Noting Maasai tribes are "constantly on the move searching for water and fresh pasture for their cattle," he describes "severe logistical challenges" health workers face when trying to reach their patients and notes." [More]
Nearly 63,000 people visit online catch-up immunization scheduling tool

Nearly 63,000 people visit online catch-up immunization scheduling tool

Children obtain protection against certain diseases by receiving vaccinations, but they commonly miss recommended times to receive these immunizations. Once a child falls behind, health care professionals typically have to construct a unique, personalized catch-up schedule for each child - often while the child waits in the treatment room. [More]