Schizophrenia News and Research RSS Feed - Schizophrenia News and Research

Schizophrenia is a chronic debilitating disorder which affects more than two million Americans, and millions more worldwide. While significant progress has been made in understanding the disease and developing treatments, there remains a significant unmet medical need. More than 50% of patients switch their medication in a given year due to either poor response or the experience of adverse events.
New Autism-Causing Genetic Variant Identified

New Autism-Causing Genetic Variant Identified

Using a novel approach that homes in on rare families severely affected by autism, a Johns Hopkins-led team of researchers has identified a new genetic cause of the disease. The rare genetic variant offers important insights into the root causes of autism, the researchers say. And, they suggest, their unconventional method can be used to identify other genetic causes of autism and other complex genetic conditions. [More]
Broad Institute of MIT researcher honored for groundbreaking research using new gene editing tool

Broad Institute of MIT researcher honored for groundbreaking research using new gene editing tool

The newest gene editing tool - called CRISPR-Cas9 - is leading to new research possibilities in cell biology and neuroscience. This includes the ability to make transgenic animal models more quickly, which helps researchers better study diseases that affect thousands of people each year. [More]
New methodology isolates functional differences between autistic, non-autistic brains

New methodology isolates functional differences between autistic, non-autistic brains

The functional differences between autistic and non-autistic brains have been isolated for the first time, following the development of a new methodology for analysing MRI scans. [More]
Study offers new insights into diagnosis and treatment of social dysfunctions

Study offers new insights into diagnosis and treatment of social dysfunctions

What if there were a pill that made you more compassionate and more likely to give spare change to someone less fortunate? UC Berkeley scientists have taken a big step in that direction. [More]
AbbVie signs exclusive worldwide license agreement with C2N for Alzheimer's disease therapies

AbbVie signs exclusive worldwide license agreement with C2N for Alzheimer's disease therapies

AbbVie today announced that it has entered into an exclusive worldwide license agreement with C2N Diagnostics, a privately held protein diagnostic and therapeutic discovery company, to develop and commercialize a portfolio of anti-tau antibodies for the treatment of Alzheimer's Disease and other neurological disorders. [More]
IU researchers reveal how Toxoplasma parasites modify brain cells

IU researchers reveal how Toxoplasma parasites modify brain cells

Rodents infected with a common parasite lose their fear of cats, resulting in easy meals for the felines. Now IU School of Medicine researchers have identified a new way the parasite may modify brain cells, possibly helping explain changes in the behavior of mice -- and humans. [More]
Janssen announces acquisition of XO1

Janssen announces acquisition of XO1

Janssen Pharmaceuticals, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson, announced today that it has acquired XO1 Limited, a privately held asset-centric virtual biopharmaceutical company founded to develop the anti-thrombin antibody ichorcumab. [More]
People with severe schizophrenia have major differences in brain networks

People with severe schizophrenia have major differences in brain networks

People with a severe form of schizophrenia have major differences in their brain networks compared to others with schizophrenia, bipolar disorder and healthy individuals, a new study from the Centre for Addiction and Mental Health shows. [More]
Cannabis abuse affects long-term memory, finds new Northwestern Medicine study

Cannabis abuse affects long-term memory, finds new Northwestern Medicine study

Teens who were heavy marijuana users - smoking it daily for about three years -- had an abnormally shaped hippocampus and performed poorly on long-term memory tasks, reports a new Northwestern Medicine study. [More]
Neuralstem reports top line data from NSI-566 Phase II trial for treatment of ALS

Neuralstem reports top line data from NSI-566 Phase II trial for treatment of ALS

Neuralstem, Inc. announced top line data from the Phase II trial of NSI-566 spinal cord-derived neural stem cells under development for the treatment of amyotrophic lateral sclerosis (ALS). The study met primary safety endpoints. The maximum tolerated dose of 16 million transplanted cells and the surgery was well tolerated. [More]
Rat study reveals role of lead in schizophrenia

Rat study reveals role of lead in schizophrenia

A study of the brains of rats exposed to lead has uncovered striking similarities with what is known about the brains of human schizophrenia patients, adding compelling evidence that lead is a factor in the onset of schizophrenia. [More]
Use of psychedelic drugs linked to less psychological distress, fewer suicidal thoughts

Use of psychedelic drugs linked to less psychological distress, fewer suicidal thoughts

A history of psychedelic drug use is associated with less psychological distress and fewer suicidal thoughts, planning and attempts, according to new research from Johns Hopkins and the University of Alabama at Birmingham. [More]
Stepped-care strategy improves function, decreases pain severity in veterans

Stepped-care strategy improves function, decreases pain severity in veterans

Although U.S. military veterans who have returned from Iraq or Afghanistan are more likely to suffer chronic pain than veterans of any other conflict in American history, little headway has been made in helping them manage the often debilitating effects of chronic pain. [More]
Study finds similar brain anomalies in people with anorexia and body dysmorphic disorder

Study finds similar brain anomalies in people with anorexia and body dysmorphic disorder

People with anorexia nervosa and with body dysmorphic disorder have similar abnormalities in their brains that affect their ability to process visual information, a new UCLA study reveals. [More]
Possible therapies to address cognitive symptoms in individuals with schizophrenia

Possible therapies to address cognitive symptoms in individuals with schizophrenia

By studying specially bred mice with specific developmental and cognitive traits resembling those seen in schizophrenia, UC San Francisco researchers have provided new evidence that abnormal rhythmic activity in particular brain cells contributes to problems with learning, attention, and decision-making in individuals with that disorder. [More]
Better interventions possible for children experiencing acute psychosis with antibodies

Better interventions possible for children experiencing acute psychosis with antibodies

Antibodies defend the body against bacterial, viral, and other invaders. But sometimes the body makes antibodies that attack healthy cells. In these cases, autoimmune disorders develop. [More]
GeneSight test better predicts antidepressant outcomes for patients with depression

GeneSight test better predicts antidepressant outcomes for patients with depression

The combinatorial, multi-gene GeneSight test has been found to better predict antidepressant treatment outcomes for patients with depression, and their use of health care resources, than any of the individual genes that comprise the test, according to a peer-reviewed analysis by investigators from the Mayo Clinic and Assurex Health, and published online by The Pharmacogenomics Journal. [More]
Oxytocin may be a potential therapeutic target for improving social function in psychiatric disorders

Oxytocin may be a potential therapeutic target for improving social function in psychiatric disorders

Researchers at the Yerkes National Primate Research Center, Emory University, have shown inducing the release of brain oxytocin may be a viable therapeutic option for enhancing social function in psychiatric disorders, including autism spectrum disorders and schizophrenia. [More]
New healthcare law may threaten federally subsidized coverage for over 2.5 million Americans

New healthcare law may threaten federally subsidized coverage for over 2.5 million Americans

A new study shows that over 2.5 million Americans who have a serious mental health condition in 34 states will become uninsured in 2016, if the Supreme Court rolls back tax credit subsidies that currently make it affordable for those individuals to purchase coverage on federally-run health insurance marketplaces under the Affordable Care Act. [More]
UC Berkeley research explores link between ADHD and childhood maltreatment

UC Berkeley research explores link between ADHD and childhood maltreatment

Young women with ADHD who have been exposed to abuse, neglect or other traumas in childhood and adolescence are at greater risk for self-injury, eating disorders and suicide than those with ADHD who were not mistreated in early youth, according to new research from UC Berkeley. [More]
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