Schizophrenia News and Research RSS Feed - Schizophrenia News and Research

Schizophrenia is a chronic debilitating disorder which affects more than two million Americans, and millions more worldwide. While significant progress has been made in understanding the disease and developing treatments, there remains a significant unmet medical need. More than 50% of patients switch their medication in a given year due to either poor response or the experience of adverse events.
External stimulation guides brain circuit’s early development

External stimulation guides brain circuit’s early development

A healthy brain has just the right ratio of cells that enhance signals (excitatory neurons) and cells that tone down signals (inhibitory neurons). These two sets of neurons start out looking exactly the same, so what determines their roles? [More]
Study finds gap in screening for lipid abnormalities among adults taking antipsychotic medications

Study finds gap in screening for lipid abnormalities among adults taking antipsychotic medications

Too few adults taking antipsychotic medications are being screened for abnormalities in lipids, which include cholesterol and triglycerides, new research from the University of Colorado Anschutz Medical Campus finds. [More]
Specific monocyte immune cells serve as link between gut bacteria and the brain

Specific monocyte immune cells serve as link between gut bacteria and the brain

A special kind of immune cell serves as an intermediary between gut bacteria and the brain. Dr. Susanne Wolf of the Max Delbruck Center for Molecular Medicine in the Helmholtz Association discovered this in tests on mice and published her findings in the journal Cell Reports. [More]
Understanding potential of illicit drug ketamine in treating depression

Understanding potential of illicit drug ketamine in treating depression

Advancing the understanding and treatment of psychiatric disorders is a principal goal of neuroscientists. As mental disorders are the leading cause of disabilities worldwide, it is concerning that there are few effective therapeutics on the market due to the lack of knowledge regarding pathophysiology. [More]
Study shows non-Hispanic blacks less likely to receive treatment for schizophrenia

Study shows non-Hispanic blacks less likely to receive treatment for schizophrenia

Non-Hispanic blacks are almost twice as likely as non-Hispanic whites to be diagnosed with schizophrenia, but they're significantly less likely to receive medication for treatment, according to researchers. [More]
Antipsychotic drug users may twice as likely to experience heart attack than non-users

Antipsychotic drug users may twice as likely to experience heart attack than non-users

A review of nine observational studies found evidence supporting an increased risk of heart attacks in patients taking antipsychotic drugs. [More]
Genes linked to educational attainment expressed in the brain during prenatal development

Genes linked to educational attainment expressed in the brain during prenatal development

An international group of 253 scientists has conducted one of the largest genetic studies to date and identified 74 genetic variants that are associated with the years of formal education that an individual completes. [More]
Children of depressed parents more likely to have recurrent episodes of depression, poor outcomes in adulthood

Children of depressed parents more likely to have recurrent episodes of depression, poor outcomes in adulthood

The latest report from a 30-year study of families at high- and low-risk for depression reveals that the offspring of depressed parents have a higher risk for depression, morbidity and mortality that persists into middle age. [More]
New research on epigenetics of lactose intolerance unravels understanding of schizophrenia

New research on epigenetics of lactose intolerance unravels understanding of schizophrenia

A new study on the epigenetics of lactose intolerance may provide an approach to understanding schizophrenia and other complex, serious illnesses [More]
New study finds genetic overlap between bipolar disorder and autism

New study finds genetic overlap between bipolar disorder and autism

A new study suggests there may be an overlap between rare genetic variations linked to bipolar disorder (BD) and those implicated in schizophrenia and autism. [More]
Candida yeast infections more common in men with schizophrenia or bipolar disorder

Candida yeast infections more common in men with schizophrenia or bipolar disorder

In a study prompted in part by suggestions from people with mental illness, Johns Hopkins researchers found that a history of Candida yeast infections was more common in a group of men with schizophrenia or bipolar disorder than in those without these disorders, and that women with schizophrenia or bipolar disorder who tested positive for Candida performed worse on a standard memory test than women with schizophrenia or bipolar disorder who had no evidence of past infection. [More]
Depression, anxiety co-occur in bipolar disorder patients following mania

Depression, anxiety co-occur in bipolar disorder patients following mania

Adults with bipolar disorder are just as likely to develop anxiety as depression following an episode of mania, according to data from a national survey of more than 34,000 adults. This finding, published today in Molecular Psychiatry, may expand our understanding of bipolar disorder to include anxiety. [More]
Brain receptor that initiates adolescent synaptic pruning appears to go awry in autism, schizophrenia

Brain receptor that initiates adolescent synaptic pruning appears to go awry in autism, schizophrenia

Research led by SUNY Downstate Medical Center has identified a brain receptor that appears to initiate adolescent synaptic pruning, a process believed necessary for learning, but one that appears to go awry in both autism and schizophrenia. [More]
Study shows cannabinoid type 2 receptor plays vital role in signal processing of the brain

Study shows cannabinoid type 2 receptor plays vital role in signal processing of the brain

The cannabinoid type 2 receptor - also called "CB2 receptor" - is a special membrane protein. Its function is to receive chemical signals that control cellular activity. "Until now, this receptor was considered part of the immune system without function in nerve cells. [More]
Snapshots of NMDA receptor activation may help in novel drug design

Snapshots of NMDA receptor activation may help in novel drug design

Structural biologists at Cold Spring Harbor Laboratory and Janelia Research Campus/HHMI, have obtained snapshots of the activation of an important type of brain-cell receptor. Dysfunction of the receptor has been implicated in a range of neurological illnesses, including Alzheimer's disease, Parkinson's disease, depression, seizure, schizophrenia, autism, and injuries related to stroke. [More]
Level of salts in the brain play critical role in controlling sleep-wake cycle

Level of salts in the brain play critical role in controlling sleep-wake cycle

Danish research is behind a new epoch-making discovery, which may prove decisive to future brain research. The level of salts in the brain plays a critical role in whether we are asleep or awake. This discovery may be of great importance to research on psychiatric diseases such as schizophrenia and convulsive fits from lack of sleep as well as post-anaesthetization confusion, according to Professor Maiken Nedergaard. [More]
Elusive brain receptor may play vital role in death of neurons from neurological diseases

Elusive brain receptor may play vital role in death of neurons from neurological diseases

Strokes, seizures, traumatic brain injury and schizophrenia: these conditions can cause persistent, widespread acidity around neurons in the brain. But exactly how that acidity affects brain function isn't well understood. [More]
Key gene changes reveal four previously unknown conditions within schizophrenia

Key gene changes reveal four previously unknown conditions within schizophrenia

Changes in key genes clearly define four previously unknown conditions within the umbrella diagnosis of schizophrenia, according to a study led by researchers from NYU Langone Medical Center published online April 28 in EBioMedicine, a Lancet journal. Cases associated with changes in each of the four genes were different from each other in terms of symptoms, intelligence level and other disease features. [More]
Group of gamma-protocadherins linked with neurons help regulate growth of dendrites

Group of gamma-protocadherins linked with neurons help regulate growth of dendrites

When you think of a neuron, imagine a tree. A healthy brain cell indeed looks like a tree with a full canopy. There's a trunk, which is the cell's nucleus; there's a root system, embodied in a single axon; and there are the branches, called dendrites. [More]
Study reveals new function for CACNA1C gene in psychiatric diseases

Study reveals new function for CACNA1C gene in psychiatric diseases

A new study shows the death of newborn brain cells may be linked to a genetic risk factor for five major psychiatric diseases, and at the same time shows a compound currently being developed for use in humans may have therapeutic value for these diseases by preventing the cells from dying. [More]
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