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An epileptic seizure, occasionally referred to as a fit, is defined as a transient symptom of "abnormal excessive or synchronous neuronal activity in the brain".
Study sheds new light on how the brain forms memories

Study sheds new light on how the brain forms memories

In the first study of its kind, UCLA and United Kingdom researchers found that neurons in a specific brain region play a key role in rapidly forming memories about every day events, a finding that may result in a better understanding of memory loss and new methods to fight it in Alzheimer's and other neurological diseases. [More]
Neurologists evaluate application of smartphones in epilepsy care

Neurologists evaluate application of smartphones in epilepsy care

While many people with epilepsy can control their seizures with medication, those unpredictable and involuntary changes in behavior and consciousness can be limiting for others. Neurologists writing in the International Journal of Epilepsy evaluated the application of smartphones in epilepsy care. [More]
Finding may pave way for much-needed treatments for people with epilepsy

Finding may pave way for much-needed treatments for people with epilepsy

An amino acid whose role in the body has been all but a mystery appears to act as a potent seizure inhibitor in mice, according to a study by researchers at Johns Hopkins. [More]
Paediatric outpatient study compares effectiveness of three alternative treatments for type 1 diabetes

Paediatric outpatient study compares effectiveness of three alternative treatments for type 1 diabetes

A Montréal research team, co-supervised by Dr. Rémi Rabasa-Lhoret from the IRCM and Dr. Laurent Legault from the Montreal Children's Hospital, undertook the first paediatric outpatient study to compare three alternative treatments for type 1 diabetes. [More]
Diagnosing brain lesions in children can be challenging, report Loyola physicians

Diagnosing brain lesions in children can be challenging, report Loyola physicians

Brain lesions in children can be especially challenging to diagnose, according to a report in the journal Frontiers in Neurology by a multidisciplinary team of Loyola University Medical Center physicians.' [More]
Duke Medicine scientists produce 3-D map of human brain stem using MRI technology

Duke Medicine scientists produce 3-D map of human brain stem using MRI technology

Scientists at Duke Medicine have produced a 3-D map of the human brain stem at an unprecedented level of detail using MRI technology. [More]
Upsher-Smith announces FDA approval of sNDA for Qudexy XR extended-release capsules

Upsher-Smith announces FDA approval of sNDA for Qudexy XR extended-release capsules

Upsher-Smith Laboratories, Inc. announced that it has received U.S. Food and Drug Administration approval of a supplemental new drug application (sNDA) for Qudexy XR (topiramate) extended-release capsules for use as initial monotherapy in patients two years of age and older who are experiencing partial-onset seizures (POS) or primary generalized tonic-clonic seizures. [More]

New insights on strategies to treat infants with seizures

New recommendations offer insights on strategies for treating infants with seizures. In an Epilepsia report, child neurologists who are members of the International League Against Epilepsy note that intervening at the time of a febrile seizure does not alter the risk for subsequent epilepsy, and there is no evidence to support the use of antiepileptic drugs for simple febrile seizures. [More]
Enzalutamide Phase 2 study for AR positive triple-negative breast cancer meets primary endpoint

Enzalutamide Phase 2 study for AR positive triple-negative breast cancer meets primary endpoint

Astellas Pharma Inc. announced that data from a Phase 2 study evaluating the investigational use of enzalutamide as a single agent for the treatment of advanced androgen receptor (AR) positive, triple-negative breast cancer (TNBC) were presented during an oral abstracts session at the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago. [More]
Researchers identify chemical pathway associated with seizures, shorter survival in patients with malignant glioma

Researchers identify chemical pathway associated with seizures, shorter survival in patients with malignant glioma

Researchers at the University of Alabama at Birmingham have identified a chemical pathway that may be associated with seizures and shorter patient survival in some patients with malignant glioma, the most common and deadly form of brain tumor. In findings published May 27 in Science Translational Medicine, the researchers suggest that a transporter known as SXC is responsible for boosting levels of glutamate in the brains of some glioma patients. [More]
Amgen to present clinical data on multiple blood cancer treatments at EHA 2015

Amgen to present clinical data on multiple blood cancer treatments at EHA 2015

Amgen today announced that it will present data from multiple Kyprolis (carfilzomib) for Injection, BLINCYTO (blinatumomab), oprozomib and Nplate (romiplostim)‎ studies at the 20th Congress of the European Hematology Association taking place in Vienna, June 11 - 14, 2015. [More]
Researchers use animal models to study how dysfunction of genes contributes to ASD risk

Researchers use animal models to study how dysfunction of genes contributes to ASD risk

Autism Spectrum Disorder (ASD) is a neurological condition that affects approximately two percent of people around the world. Although several genes have been linked to multiple concurring conditions of ASD, the process that explains how specific genetic variants lead to behaviors characteristic of the disorder remains elusive. [More]
Treatment outcomes in type 1 diabetes could be improved across all age groups

Treatment outcomes in type 1 diabetes could be improved across all age groups

In a sweeping analysis assessing the current state of diabetes treatment in the U.S., T1D Exchange researchers conclude that there remains considerable room for improving treatment outcomes in type 1 diabetes across all age groups, but especially for adolescents and young adults. [More]
Discovery has clear implications in the quest for new epilepsy treatments

Discovery has clear implications in the quest for new epilepsy treatments

The mission of neural stem cells located in the hippocampus, one of the main regions of the brain, is to generate new neurons during the adult life of mammals, including human beings, of course, and their function is to participate in certain types of learning and responses to anxiety and stress. [More]
UCB sponsoring several presentations on Cimzia for Crohn's disease at DDW 2015

UCB sponsoring several presentations on Cimzia for Crohn's disease at DDW 2015

UCB, a global biopharmaceutical company focusing on immunology and neurology treatment and research, is sponsoring several data presentations on Cimzia (certolizumab pegol) at Digestive Disease Week 2015, taking place in Washington, DC from May 16-19. [More]
DNMT1 gene essential to maintain breast and cancer stem cells

DNMT1 gene essential to maintain breast and cancer stem cells

The gene and hormone soup that enables women to breastfeed their newborns also can be a recipe for breast cancer, particularly when the first pregnancy is after age 30. [More]
Orexigen Therapeutics provides update on business and financial results for Q1 2015

Orexigen Therapeutics provides update on business and financial results for Q1 2015

Orexigen Therapeutics, Inc. today announced business and financial results for the first quarter ended March 31, 2015. [More]
ViiV Healthcare initiates Phase III trial to evaluate dolutegravir and rilpivirine in HIV patients

ViiV Healthcare initiates Phase III trial to evaluate dolutegravir and rilpivirine in HIV patients

ViiV Healthcare today announced the start of a Phase III clinical trial programme to evaluate the safety and efficacy of dolutegravir (Tivicay) and rilpivirine (Edurant) as maintenance therapy for adult patients with HIV. [More]
Electroclinical triggers for repeat MRI in intractable epilepsy identified

Electroclinical triggers for repeat MRI in intractable epilepsy identified

Researchers have outlined the electroclinical features typically associated with bottom-of-sulcus dysplasia, the surgical removal of which often cures epilepsy in affected patients. [More]
Parents share arduous, circuitous journey to get referrals for childhood epilepsy surgery

Parents share arduous, circuitous journey to get referrals for childhood epilepsy surgery

Having a child diagnosed with epilepsy can be a frightening and confusing time. Now, parents share their arduous and "circuitous" journey to get referrals for pediatric epilepsy surgery once their child's disease stops responding to anti-seizure medications. The UCLA study sheds light on the difficulties parents face obtaining specialty and sub-specialty care for their children during an already stressful time. [More]
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