Seizure News and Research RSS Feed - Seizure News and Research

An epileptic seizure, occasionally referred to as a fit, is defined as a transient symptom of "abnormal excessive or synchronous neuronal activity in the brain".
Upsher-Smith presents favorable data from PREVAIL OLE study of Qudexy XR capsules

Upsher-Smith presents favorable data from PREVAIL OLE study of Qudexy XR capsules

Upsher-Smith Laboratories, Inc. presented data from a 52-week, open-label extension study (PREVAIL OLE) showing that Qudexy XR (topiramate) extended-release capsules offered a long-term adjunctive treatment option with a favorable tolerability profile for a high proportion of patients with refractory partial-onset seizures (POS). [More]
New CUMC study finds DNA anomalies in kids with chronic kidney disease

New CUMC study finds DNA anomalies in kids with chronic kidney disease

A significant proportion of children with chronic kidney disease (CKD) have unsuspected chromosomal imbalances, including DNA anomalies that have been linked to neurocognitive disorders, according to a new Columbia University Medical Center study. [More]
Electronic micropump combined with anticonvulsant drug may treat brain diseases

Electronic micropump combined with anticonvulsant drug may treat brain diseases

Many potentially efficient drugs have been created to treat neurological disorders, but they cannot be used in practice. Typically, for a condition such as epilepsy, it is essential to act at exactly the right time and place in the brain. [More]
New priority program set to develop next generation of optogenetic tools

New priority program set to develop next generation of optogenetic tools

Optogenetics is a new field of research that introduces light-sensitive proteins into cells in a genetically targeted manner, for example, to obtain information on signalling pathways and the function of neurons in a living organism. [More]
Astellas Pharma, Medivation announce topline results from enzalutamide Phase 2 STRIVE trial

Astellas Pharma, Medivation announce topline results from enzalutamide Phase 2 STRIVE trial

Astellas Pharma Inc. and Medivation, Inc. today announced topline results from the Phase 2 STRIVE trial comparing enzalutamide with bicalutamide in a study population of men with non-metastatic or metastatic castration-resistant prostate cancer. [More]
One in five college students experiences exploding head syndrome

One in five college students experiences exploding head syndrome

Washington State University researchers have found that an unexpectedly high percentage of young people experience "exploding head syndrome," a psychological phenomenon in which they are awakened by abrupt loud noises, even the sensation of an explosion in their head. [More]
Only few studies demonstrate the effectiveness of marijuana

Only few studies demonstrate the effectiveness of marijuana

While many states have pushed for new laws to legalize the use of marijuana for medical reasons, there are few well-controlled studies that demonstrate its effectiveness. [More]
Deuterium-containing sigma-1 agonist demonstrates anti-seizure, anti-inflammatory effects in TBI model

Deuterium-containing sigma-1 agonist demonstrates anti-seizure, anti-inflammatory effects in TBI model

Research results published in the Journal of Neurotrauma and conducted by the Walter Reed Army Institute of Research (WRAIR) as part of a collaboration with Concert Pharmaceuticals, Inc. showed that a novel deuterium-containing sigma-1 agonist invented at Concert, called C-10068, demonstrated anti-seizure and anti-inflammatory effects in a preclinical model of traumatic brain injury (TBI). [More]
Anxiety and déjà vu: an interview with Dr Christine Wells, Sheffield Hallam University

Anxiety and déjà vu: an interview with Dr Christine Wells, Sheffield Hallam University

It’s thought that the neural basis of déjà vu is located in the temporal lobes, a region of the brain strongly associated with the storage and retrieval of memories. One source of support for this is evidence from individuals with temporal lobe epilepsy, some of whom experience déjà vu episodes as part of seizure-related auras... [More]
Direct brain responsive neurostimulator reduces seizures, improves quality of life

Direct brain responsive neurostimulator reduces seizures, improves quality of life

Piotr Olejniczak, MD, PhD, LSU Health New Orleans Professor of Neurology and Director of the Epilepsy Center, contributed to a study of the long-term effectiveness of the first direct brain responsive neurostimulator for partial onset, or focal, seizures that cannot be controlled with medication. [More]
LSU Health New Orleans finalizes deal with CB BioSciences

LSU Health New Orleans finalizes deal with CB BioSciences

The Office of Technology Management at LSU Health New Orleans has finalized a deal with CB BioSciences, Inc., a startup drug development company to build a platform around the intellectual property portfolio of Chu Chen, PhD, LSU Health New Orleans Professor of Neuroscience. [More]
Study shows how cannabidiol works within cells

Study shows how cannabidiol works within cells

A team of Stony Brook University researchers have identified fatty acid binding proteins (FABPs) as intracellular transporters for two ingredients in marijuana, THC and CBD (cannabidiol). [More]
Use of STAN in addition to usual monitoring does not improve perinatal outcomes

Use of STAN in addition to usual monitoring does not improve perinatal outcomes

In a study to be presented on Feb. 5 in an oral plenary session at 8 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting™, in San Diego, researchers will report that use of the ST segment (STAN) as an adjunct to conventional intrapartum electronic fetal heart rate monitoring did not improve perinatal outcomes or decrease operative deliveries in hospitals in the United States. [More]
Johns Hopkins pediatricians offer guidelines on choosing between urgent care and ER

Johns Hopkins pediatricians offer guidelines on choosing between urgent care and ER

Parents have a natural tendency to fear the worst when it comes to their children and often opt for a "better safe than sorry" course of action, Canares says, but the truth is many situations don't warrant a trip to the emergency room. At the other end of the spectrum are cases that clearly require emergency attention but end up in urgent care instead — a less common scenario, Canares says. [More]
Prone position linked to epilepsy sudden death risk

Prone position linked to epilepsy sudden death risk

Around three-quarters of patients who have a sudden unexpected death in epilepsy are found lying in the prone position, show meta-analysis findings. [More]
New survey finds long-term benefits of brain surgery in patients with epilepsy

New survey finds long-term benefits of brain surgery in patients with epilepsy

Brain surgery for otherwise hard-to-treat epilepsy is effective for up to 15 years, according to a new survey by Henry Ford Hospital physicians. [More]
Research findings may accelerate work to safely control diabetes

Research findings may accelerate work to safely control diabetes

For those with diabetes, managing blood sugar is a balancing act -- if blood sugar is too high it raises the risk for nerve damage, blindness, kidney failure, and heart trouble, and if too low it can lead to a seizure or unconsciousness. [More]
International scientists take new path in epilepsy research

International scientists take new path in epilepsy research

An international team of scientists together with the University of Bonn Hospital have taken a new path in the research into causes of epilepsy: The researchers determined the networks of the active genes and, like a dragnet, looked for the "main perpetrators" using a computer model. [More]
Alexza begins Phase 2a study of AZ-002 for ARS-related epilepsy management

Alexza begins Phase 2a study of AZ-002 for ARS-related epilepsy management

Alexza Pharmaceuticals, Inc. announced today that it has initiated a Phase 2a study of AZ-002 (Staccato alprazolam), which is being developed for the management of epilepsy in patients with acute repetitive seizures (ARS). [More]
Sheffield researchers use ‘Conversation Analysis’ to improve dementia diagnosis

Sheffield researchers use ‘Conversation Analysis’ to improve dementia diagnosis

ANALYSING distinct features of conversation and how patients describe memory loss could improve the early diagnosis of dementia, and help those whose memory concerns are not due to dementia receive reassurance sooner. [More]
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