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An epileptic seizure, occasionally referred to as a fit, is defined as a transient symptom of "abnormal excessive or synchronous neuronal activity in the brain".
Knowledge and access barriers bar epilepsy patients from surgery

Knowledge and access barriers bar epilepsy patients from surgery

The unfamiliarity of some neurologists with recommended practice standards, coupled with access barriers, may be preventing eligible patients with epilepsy from undergoing surgical treatment, survey findings suggest. [More]
SPECT scan measures brain activity during seizures

SPECT scan measures brain activity during seizures

Loyola University Medical Center is offering epileptic patients an imaging scan that records brain activity during seizures. [More]
UK doctors to test cannabis-based medicine for children with severe epilepsy

UK doctors to test cannabis-based medicine for children with severe epilepsy

Children with severe epilepsy could be helped by a new treatment derived from the cannabis plant. [More]
New research could revolutionise global diagnostic procedures for epilepsy

New research could revolutionise global diagnostic procedures for epilepsy

Pioneering new research by the University of Exeter could revolutionise global diagnostic procedures for one of the most common forms of epilepsy. [More]
Chemical chaperone: A new therapeutic option for epilepsy

Chemical chaperone: A new therapeutic option for epilepsy

Researchers found out that the conformational defect in a specific protein causes Autosomal Dominant Lateral Temporal Lobe Epilepsy (ADLTE) which is a form of familial epilepsy. They showed that treatment with chemical corrector called "chemical chaperone" ameliorates increased seizure susceptibility in a mouse model of human epilepsy by correcting the conformational defect. [More]
Study shows link between cardiac abnormalities, sudden unexpected death in epilepsy

Study shows link between cardiac abnormalities, sudden unexpected death in epilepsy

Groundbreaking findings describing the link between cardiac abnormalities and sudden unexpected death in epilepsy (SUDEP) will be presented at the American Epilepsy Society's Annual Meeting in December. [More]
New study explores reliability of optogenetics as method of intervention of temporal lobe seizures

New study explores reliability of optogenetics as method of intervention of temporal lobe seizures

Optogenetics is one of the hottest tools in biomedical research today, a method that uses gene therapy to deliver light-sensitive proteins into specific cells. This new tool allows researchers to interact with a single cell or a network of cells with exquisite precision. Whereas imaging and other technologies allow researchers to watch the brain in action, optogenetics enables them to influence those actions. [More]
CNF names Elizabeth A. Thiele as winner of 2014 Infantile Spasms Heroes Award

CNF names Elizabeth A. Thiele as winner of 2014 Infantile Spasms Heroes Award

Today the Child Neurology Foundation, named Elizabeth A. Thiele, MD, PhD, as its 2014 Infantile Spasms (IS) Heroes Award winner to help kick off IS Awareness Week (December 5-11, 2014). The IS Heroes Award was established in 2010 by CNF, www.childneurologyfoundation.org, to recognize a deserving healthcare professional for making a positive difference in the life of a child with infantile spasms. [More]
Identifying infant and toddler injuries that require emergency medical care

Identifying infant and toddler injuries that require emergency medical care

Bianca Edison, MD, MS is an attending physician in the Children's Orthopaedic Center at Children's Hospital Los Angeles, and is assistant clinical professor of Orthopaedics at the Keck School of Medicine of the University of Southern California. Edison is a licensed, Board-Certified pediatrician and Fellow of the American Academy of Pediatrics who completed a fellowship in Primary Care SportsMedicine. Her interests and experience include orthopaedic conditions affecting young children, teens, and athletes. Here she reviews common infant and toddler injuries, and how parents can determine if emergency medical care is needed. [More]
External artificial pancreas improves glucose control, reduces hypoglycemia risk

External artificial pancreas improves glucose control, reduces hypoglycemia risk

The world's first clinical trial comparing three alternative treatments for type 1 diabetes was conducted in Montréal by researchers at the IRCM and the University of Montreal, led by endocrinologist Dr. Rémi Rabasa-Lhoret. [More]
Janssen announces submission of NDA for three-month paliperidone palmitate

Janssen announces submission of NDA for three-month paliperidone palmitate

Janssen Research & Development, LLC today announced the submission of a New Drug Application (NDA) for three-month atypical antipsychotic paliperidone palmitate to the U.S. Food and Drug Administration. The NDA seeks approval for the medication as a treatment for schizophrenia in adults. [More]
Pros and cons of medical marijuana to be discussed at Queensland Epilepsy Symposium

Pros and cons of medical marijuana to be discussed at Queensland Epilepsy Symposium

The pros and cons of medical marijuana is a discussion focus at the fifth annual Queensland Epilepsy Symposium, Epilepsy – On the Horizon. [More]
McLean Hospital lab explores use of stem cell therapy to treat epilepsy

McLean Hospital lab explores use of stem cell therapy to treat epilepsy

McLean Hospital and Harvard Stem Cell Institute scientists have new evidence that stem cell transplantation could be a worthwhile strategy to help epileptics who do not respond to anti-seizure drugs. [More]
Epilepsy: A true window on the brain

Epilepsy: A true window on the brain

Rapidly emerging technologies, novel imaging techniques, the development of new therapies and new genes, have given researchers and clinicians an extraordinary ability to explore the brain at the cellular, genetic and neural levels. While current epilepsy research may seem like it's ripped from the pages of a science fiction novel, it's real—and even pretty cool. [More]
New statistical test can help doctors locate seizures, make surgery more effective

New statistical test can help doctors locate seizures, make surgery more effective

A new statistical test that looks at the patterns of high-frequency network activity flow from brain signals can help doctors pinpoint the exact location of seizures occurring in the brain and make surgery more effective, according to researchers at Georgia State University and Emory University School of Medicine. [More]
Researchers discover link between seizures and migraines

Researchers discover link between seizures and migraines

Seizures and migraines have always been considered separate physiological events in the brain, but now a team of engineers and neuroscientists looking at the brain from a physics viewpoint discovered a link between these and related phenomena. [More]
Hypocalcaemic seizure surveillance highlights UK public health policy failings

Hypocalcaemic seizure surveillance highlights UK public health policy failings

The occurrence of 91 confirmed or probable hypocalcaemic seizures in children with vitamin D deficiency over a 2-year period in the UK highlights a failure to promote appropriate supplementation. [More]
Epileptic mothers in the dark about pregnancy risk?

Epileptic mothers in the dark about pregnancy risk?

A new study has highlighted the need for more research into the safety of using anti-epileptic drugs during pregnancy. [More]
Cypher researchers identify new genetic cause of severe epileptic encephalopathy

Cypher researchers identify new genetic cause of severe epileptic encephalopathy

Cypher Genomics, Inc., the genome informatics company, announced today the identification of de novo KCNB1 missense mutations as a novel genetic cause of severe epileptic encephalopathy. Cypher’s co-founder and Chief Scientific Officer Ali Torkamani, Ph.D. reviewed the data today at a platform presentation at the ASHG 2014 meeting being held October 18 to 22 in San Diego. [More]
FDA accepts Eisai's sNDA for perampanel drug for treatment of PGTC seizures

FDA accepts Eisai's sNDA for perampanel drug for treatment of PGTC seizures

Eisai Inc. announced today that the U.S. Food and Drug Administration (FDA) accepted for review the company's Supplemental New Drug Application (sNDA) for its in-house-discovered AMPA receptor antagonist perampanel for the treatment of primary generalized tonic-clonic (PGTC) seizures. [More]