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Sepsis is a life-threatening illness. Your body's response to a bacterial infection usually causes it. Your immune system goes into overdrive, overwhelming normal processes in your blood. The result is that small blood clots form, blocking blood flow to vital organs. This can lead to organ failure. Babies, old people and those with weakened immune systems are most likely to get sepsis. But even healthy people can become deathly ill from it. A quick diagnosis can be crucial, because one third of people who get sepsis die from it. Sepsis is usually treated in a hospital intensive care unit (ICU). IV antibiotics and fluids may be given to try to knock out the infection and to keep blood pressure from dropping too low. Patients may also need respirators to help them breathe.
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BIOCRATES launches first-ever bile acids kit based on targeted metabolite quantitation

BIOCRATES launches first-ever bile acids kit based on targeted metabolite quantitation

Austrian BIOCRATES Life Sciences AG, internationally renowned developer and marketer of innovative targeted metabolomics solutions, further expands its range of metabolomics-based kits with the addition of its assay for the determination of endogenous bile acids, allowing a panel of up to 19 analytes to be simultaneously quantitated from a single 10 µL sample of human or mouse plasma. [More]
Educating clinicians can reduce sepsis patient mortality and lower hospital costs

Educating clinicians can reduce sepsis patient mortality and lower hospital costs

Sepsis is the tenth leading cause of death in the United States, and new research published in the Journal for Healthcare Quality (JHQ) shows that educating clinicians about expediting diagnosis and administration of antibiotics can reduce sepsis patient mortality and lower hospital costs. [More]
UAB scientist receives R01 grant to study transmission of deadly bacteria from mothers to infants

UAB scientist receives R01 grant to study transmission of deadly bacteria from mothers to infants

New research from the University of Alabama at Birmingham School of Optometry will study the transmission of a bacteria that up to 40 percent of healthy women carry, which becomes deadly when passed on to infants during birth. [More]
OMRF receives $14.5 million grant from NIH to continue research on anthrax

OMRF receives $14.5 million grant from NIH to continue research on anthrax

The National Institutes of Health has awarded the Oklahoma Medical Research Foundation a five-year, $14.5 million grant to continue its research on anthrax and the bacteria's effects on humans. [More]
Researchers shed light on the dual action of aspirin

Researchers shed light on the dual action of aspirin

Hugely popular non-steroidal anti-inflammation drugs like aspirin, naproxen (marketed as Aleve) and ibuprofen (Advil, Motrin) all work by inhibiting or killing an enzyme called cyclooxygenase - a key catalyst in production of hormone-like lipid compounds called prostaglandins that are linked to a variety of ailments, from headaches and arthritis to menstrual cramps and wound sepsis. [More]
Actavis reports positive results from ceftazidime-avibactam Phase III studies in cIAI patients

Actavis reports positive results from ceftazidime-avibactam Phase III studies in cIAI patients

Actavis plc today confirmed positive topline results from RECLAIM-1 and -2, pivotal Phase III studies evaluating the potential for the investigational antibiotic, ceftazidime-avibactam as a treatment for adult hospitalized patients with complicated intra-abdominal infections. [More]
Researchers reveal importance of highly specialised immune cells in killing melanoma cells

Researchers reveal importance of highly specialised immune cells in killing melanoma cells

Melbourne researchers have revealed the critical importance of highly specialised immune cells, called natural killer cells, in killing melanoma cells that have spread to the lungs. [More]
Babies suffering from life-threatening bacterial infections could benefit from improved treatment

Babies suffering from life-threatening bacterial infections could benefit from improved treatment

Babies suffering from life-threatening bacterial infections such as sepsis could benefit from improved treatment, thanks to a ground-breaking study. [More]
Inovio Pharmaceuticals reports increased revenue in second quarter 2014

Inovio Pharmaceuticals reports increased revenue in second quarter 2014

Inovio Pharmaceuticals, Inc. today reported financial results for the quarter ended June 30, 2014. Total revenue was $3.8 million and $6.2 million for the three and six months ended June 30, 2014, compared to $786,000 and $2.2 million for the same periods in 2013. [More]
Receipt of nutrition via feeding tube may be harmful for ICU patients

Receipt of nutrition via feeding tube may be harmful for ICU patients

Among mechanically ventilated intensive care unit (ICU) patients, receipt of high-protein nutrition via a feeding tube enriched with immune-modulating nutrients (such as glutamine, omega-3 fatty acids, and antioxidants) vs standard high-protein nutrition did not result in a significant difference in the incidence of new complications and may be harmful, as suggested by an increased risk of death at 6 months, according to a study in the August 6 issue of JAMA. [More]
Researchers reveal obesity paradox among older Americans suffering from sepsis

Researchers reveal obesity paradox among older Americans suffering from sepsis

University of Michigan Health System researchers revealed an obesity paradox among older Americans suffering from sepsis. [More]
Emergency department closures can affect death rates, finds UCSF research

Emergency department closures can affect death rates, finds UCSF research

In the first analysis of its kind, UC San Francisco research shows that emergency department closures can have a ripple effect on patient outcomes at nearby hospitals. [More]
Astute Medical, OCD partner to expand access to new acute kidney injury test

Astute Medical, OCD partner to expand access to new acute kidney injury test

Astute Medical, Inc. today announced a strategic collaboration with Ortho-Clinical Diagnostics, Inc. that will expand access to a new test that assesses critically ill patients for risk of acute kidney injury (AKI), a prevalent and deadly condition. [More]
Brain network measures placebo effects in Parkinson's disease patients

Brain network measures placebo effects in Parkinson's disease patients

Investigators at The Feinstein Institute for Medical Research have utilized a new image-based strategy to identify and measure placebo effects in randomized clinical trials for brain disorders. The findings are published in the August issue of The Journal of Clinical Investigation. [More]
First publication describing use of CytoSorb during cardiac surgery

First publication describing use of CytoSorb during cardiac surgery

CytoSorbents Corporation, a critical care immunotherapy company commercializing its CytoSorb® cytokine adsorber in multiple countries worldwide, announced the PDF availability of the first publication describing the use of CytoSorb® intra-operatively during cardiac surgery at the Ludwig Maximilian University of Munich Hospital - Grosshadern Campus, in Germany. [More]
Researchers release evidence substantiating unexpected dual role of immune system

Researchers release evidence substantiating unexpected dual role of immune system

University of Leicester researchers have released evidence substantiating an unexpected dual role of an important component of the immune system. [More]
'Pure mass of HES molecules' explains toxicity to renal tubule cells

'Pure mass of HES molecules' explains toxicity to renal tubule cells

The increased risk of kidney injury related to the use of hydroxyethyl starch (HES) in resuscitation fluids reflects the mass of HES molecules, according to a report in Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS). [More]
Study: Minimally invasive aortic repair procedure safer for patients

Study: Minimally invasive aortic repair procedure safer for patients

Researchers at the University of California, San Diego School of Medicine have documented the safety benefits of aortic stent grafts inserted during minimally invasive surgery to repair abdominal aortic aneurysms - weaknesses in the body's largest artery that can rupture, causing potentially lethal internal bleeding. [More]
Keck Medicine of USC study identifies potential therapeutic target for inflammation

Keck Medicine of USC study identifies potential therapeutic target for inflammation

Molecular microbiologists from the Keck School of Medicine of the University of Southern California have discovered that mice lacking a specific component of the immune system are completely resistant to sepsis, a potentially fatal complication of infection. [More]
Scientists uncover mechanisms that can protect against lethal bacteria

Scientists uncover mechanisms that can protect against lethal bacteria

An important development in understanding how the bacterium that causes pneumonia, meningitis and septicaemia remains harmlessly in the nose and throat has been discovered at the University of Liverpool's Institute of Infection and Global Health. [More]