Sepsis News and Research RSS Feed - Sepsis News and Research

Sepsis is a life-threatening illness. Your body's response to a bacterial infection usually causes it. Your immune system goes into overdrive, overwhelming normal processes in your blood. The result is that small blood clots form, blocking blood flow to vital organs. This can lead to organ failure. Babies, old people and those with weakened immune systems are most likely to get sepsis. But even healthy people can become deathly ill from it. A quick diagnosis can be crucial, because one third of people who get sepsis die from it. Sepsis is usually treated in a hospital intensive care unit (ICU). IV antibiotics and fluids may be given to try to knock out the infection and to keep blood pressure from dropping too low. Patients may also need respirators to help them breathe.
Further Reading
Researchers explore phenomenon that causes late mortality in sepsis patients

Researchers explore phenomenon that causes late mortality in sepsis patients

It's known that many patients die in the months and years after sepsis. But no one has known if this increased risk of death (in the 30 days to 2 years after sepsis) is because of sepsis itself, or because of the pre-existing health conditions the patient had before acquiring the complication. [More]
HbA1C test can effectively detect hidden diabetes among hyperglycemia patients

HbA1C test can effectively detect hidden diabetes among hyperglycemia patients

A retrospective review of medical records found the HbA1C test, commonly used to diagnose and manage diabetes, can effectively detect hidden disease among hospital patients with hyperglycemia, commonly known as high blood sugar. [More]
New method helps scavenge inflammatory molecules that mediate sepsis in mice

New method helps scavenge inflammatory molecules that mediate sepsis in mice

Sepsis is a life-threatening complication of infection in which the molecules that the body releases to fight an infection trigger widespread inflammatory responses, resulting in damage to multiple organ systems. [More]
Overnight extubations in ICU patients linked to higher mortality

Overnight extubations in ICU patients linked to higher mortality

Adult patients who were admitted to U.S. intensive care units had higher mortality if they were extubated overnight. The results reported at the ATS 2016 International Conference may discourage hospital administrators from expanding the practice of overnight extubations in ICUs, which the lead author noted are rapidly being transformed to provide continuity of care. [More]
Automated process uses EMR to identify patients with potential for clinical deterioration

Automated process uses EMR to identify patients with potential for clinical deterioration

Hospitalized patients can deteriorate quickly, requiring prompt identification and treatment, especially since each hour of treatment delay can increase the risk of mortality. [More]
Risk factors for hospital readmission after pediatric neurosurgical procedures

Risk factors for hospital readmission after pediatric neurosurgical procedures

Researchers at The University of Alabama at Birmingham have determined specific risk factors associated with hospital readmission following pediatric neurosurgery. [More]
Innovative technology in NICU can predict risk of major infections in premature or critically ill babies

Innovative technology in NICU can predict risk of major infections in premature or critically ill babies

A new technology in the Neonatal Intensive Care Unit at UC San Diego Health is able to predict the risk of life-threatening infections up to 24 hours before they appear in severely premature or critically ill infants. Infection is the leading cause of death in this fragile patient population. [More]
Research shows spleen MZ B cells produce signaling proteins involved in inflammatory responses

Research shows spleen MZ B cells produce signaling proteins involved in inflammatory responses

The inability to adequately respond to infection can cause a whole-body state of inflammation known as sepsis. This can eventually lead to systemic inflammatory response syndrome (SIRS), and even death. [More]
Small doses of cancer drug may be potential treatment for sepsis and other pandemics

Small doses of cancer drug may be potential treatment for sepsis and other pandemics

Results from laboratory experiments and mouse studies suggest that small doses of drugs from a specific class of approved cancer medications called topoisomerase 1 (top1) inhibitors may protect against the overwhelming immune response to infection that sometimes leads to sepsis, a bacterial condition that kills as many as 500,000 people in the United States each year. [More]
Therapies based on alpha defensins could help treat rheumatoid arthritis

Therapies based on alpha defensins could help treat rheumatoid arthritis

Arthritis and other inflammatory conditions could be helped by new insights into how the immune response is switched off. [More]
Researchers develop novel method to store microfluidic devices for CD4 T cell testing

Researchers develop novel method to store microfluidic devices for CD4 T cell testing

Providing vital health care services to people in developing countries without reliable electricity, refrigeration and state-of-the-art medical equipment poses a number of challenges. Inspired by pregnancy tests, researchers from Florida Atlantic University, Stanford University, and Baskent University in Turkey, have developed a novel method to store microfluidic devices for CD4 T cell testing in extreme weather conditions for up to six months without refrigeration. [More]
Tackling superbugs with antibiotic resistance breakers: an interview with Professor Colin Garner, Chief Executive, Antibiotic Research UK

Tackling superbugs with antibiotic resistance breakers: an interview with Professor Colin Garner, Chief Executive, Antibiotic Research UK

Superbugs – or to give them their correct name, antibiotic resistant bacteria – arise on repeated exposure to antibiotics. In any population of bacteria there will be a few that are antibiotic resistant (approximately 1 in 100 million bacteria). If these bacteria are allowed to grow and multiply, an antibiotic resistant infection results. [More]
Weekend effect in hospitals affect kidney stone treatment, outcomes

Weekend effect in hospitals affect kidney stone treatment, outcomes

Patients with severe cases of kidney stones are 26 percent less likely to receive timely treatment when they're admitted to the hospital on the weekend, according to a study by researchers at Loyola Medicine and Loyola University Chicago Stritch School of Medicine. [More]
Researchers find evidence that protein involved in regulating inflammation has anti-septic effects

Researchers find evidence that protein involved in regulating inflammation has anti-septic effects

Sepsis represents a serious complication of infection and is one of the leading causes of death and critical illness worldwide due in part to the lack of effective therapies. A report in the American Journal of Pathology provides evidence from both mouse and human studies that SHARPIN, a protein involved in regulating inflammation, has anti-septic effects. These findings may spur development of novel sepsis treatments. [More]
Spending less than $5 per person could save millions of maternal, child lives every year

Spending less than $5 per person could save millions of maternal, child lives every year

By spending less than $5 per person on essential health care services such as contraception, medication for serious illnesses and nutritional supplements, millions of maternal and child lives could be saved every year, according to a new analysis led by the Johns Hopkins Bloomberg School of Public Health. [More]
New study suggests that Neanderthals across Europe may have diseases carried out of Africa

New study suggests that Neanderthals across Europe may have diseases carried out of Africa

A new study suggests that Neanderthals across Europe may well have been infected with diseases carried out of Africa by waves of anatomically modern humans, or Homo sapiens. As both were species of hominin, it would have been easier for pathogens to jump populations, say researchers. This might have contributed to the demise of Neanderthals. [More]
Inflectra (infliximab-dyyb) approved for multiple indications

Inflectra (infliximab-dyyb) approved for multiple indications

The U.S. Food and Drug Administration today approved Inflectra (infliximab-dyyb) for multiple indications. Inflectra is administered by intravenous infusion. This is the second biosimilar approved by the FDA. [More]
UAM implements family-centered care model to provide better patient outcomes

UAM implements family-centered care model to provide better patient outcomes

Family presence when a child is undergoing tracheal intubation in a pediatric intensive care unit (PICU) can safely be implemented as part of a family-centered care model, reported a research team led by a University of Arkansas for Medical Sciences professor in the March 7 issue of JAMA Pediatrics. [More]
Caloric restriction leads to fatale weakening of the immune system

Caloric restriction leads to fatale weakening of the immune system

It's already well known that a diet may have a life-extending effect. Researchers from Leibniz Institute on Aging - Fritz Lipmann Institute in Jena, Germany, now showed that besides improving the functionality of stem cells in mice, a caloric restriction also leads to a fatale weakening of their immune system - counteracting the life-lengthening effect of a diet. [More]
New study demonstrates role of hospital nurses in ensuring safe outcomes for surgical patients

New study demonstrates role of hospital nurses in ensuring safe outcomes for surgical patients

A new study from the University of Pennsylvania School of Nursing's Center for Health Outcomes and Policy Research (CHOPR) shows that patients, who undergo elective hip and knee surgery in hospitals with inadequate nurse staffing and poor nurse work environments, are more likely to require re-hospitalization. [More]
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