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New polymer gel could help create swallowable devices for ultra-long drug delivery

New polymer gel could help create swallowable devices for ultra-long drug delivery

Medical devices designed to reside in the stomach have a variety of applications, including prolonged drug delivery, electronic monitoring, and weight-loss intervention. However, these devices, often created with nondegradable elastic polymers, bear an inherent risk of intestinal obstruction as a result of accidental fracture or migration. As such, they are usually designed to remain in the stomach for a limited time. [More]
Important new target identified for ovarian cancer therapy

Important new target identified for ovarian cancer therapy

Scientists at Lawson Health Research Institute have uncovered an important new target for ovarian cancer therapy. Contrary to current research this new study found that LKB1, a molecule that regulates the metabolism of many adult cells, is an important molecule in the cancer's promotion and survival. [More]
Expanded use for IntelliCap with further CE Mark for aspiration of fluids

Expanded use for IntelliCap with further CE Mark for aspiration of fluids

The small, pill-shaped IntelliCap wireless medical device is opening up research opportunities into the impact of the small intestine microbiota on health and disease. For the first time, scientists have been able to obtain and analyse samples of the small intestine’s microbiome in a non-invasive way. [More]
NeoGenomics announces launch of new germline cancer predisposition testing services

NeoGenomics announces launch of new germline cancer predisposition testing services

NeoGenomics, Inc., a leading provider of cancer-focused genetic testing services, announced today the launch of a new line of germline cancer predisposition testing services. The new tests include comprehensive testing for BRCA1 and BRCA2 encompassing an analysis of all exons and adjacent intronic regions. [More]
Natural supplement may improve quality of life for people who have celiac disease and gluten intolerance

Natural supplement may improve quality of life for people who have celiac disease and gluten intolerance

University of Alberta researchers may have found a way to help people with celiac disease enjoy the wide variety of foods they normally have to shun. [More]
Georgia researchers develop new tools to genetically manipulate parasite that causes cryptosporidiosis

Georgia researchers develop new tools to genetically manipulate parasite that causes cryptosporidiosis

Researchers at the University of Georgia have developed new tools to study and genetically manipulate cryptosporidium, a microscopic parasite that causes the diarrheal disease cryptosporidiosis. [More]
New Rush Center for Obesity and Bariatric Surgery opens

New Rush Center for Obesity and Bariatric Surgery opens

Being overweight or obese isn't a cosmetic problem. These conditions greatly raise your risk for other health problems including heart disease, stroke, Type 2 diabetes, some cancers and other chronic issues. [More]
University of Oslo researchers find the cause of coeliac disease

University of Oslo researchers find the cause of coeliac disease

Professor Ludvig M. Sollid and his colleagues at the University of Oslo have found the cause of coeliac disease. To do so required really going into depth, right down to molecular level. [More]
Spouses & Relatives Of Celiac Disease Patients At Risk For Autoimmune Diseases

Spouses & Relatives Of Celiac Disease Patients At Risk For Autoimmune Diseases

Both spouses and first-degree relatives of patients with celiac disease are at increased risk of nonceliac autoimmune disease, according to a study in the July issue of Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association. This risk represents a mixture of genetic, environmental and ascertainment bias mechanisms. [More]
Small intestine causes chronic inflammation in obese patients

Small intestine causes chronic inflammation in obese patients

Obesity is caused by numerous and complex factors, some of which are as yet unsuspected. Scientists from the CNRS, INSERM, UPMC and Université Paris Descartes, working with research clinicians from Paris Public Hospitals (AP-HP) have now shown that severe obesity is accompanied by inflammation of the small intestine and enhanced immune response in that region. [More]
Celimmune to provide oral presentation on AMG 714 antibody at 16th International Coeliac Disease Symposium

Celimmune to provide oral presentation on AMG 714 antibody at 16th International Coeliac Disease Symposium

Celimmune LLC, a clinical development-stage immunotherapy company focused on treating and preventing autoimmune diseases, announced today that Dr. Francisco Leon, CEO and Chief Medical Officer, will provide an oral presentation on an abstract related to the company's lead product candidate, AMG 714, at the 16th International Coeliac Disease Symposium, June 24, 2015, in Prague, Czech Republic. [More]
CHLA researchers provide new hope for infants with short bowel syndrome

CHLA researchers provide new hope for infants with short bowel syndrome

Investigators at Children's Hospital Los Angeles are providing new hope for babies with short bowel syndrome (SBS) by developing a novel model of SBS in zebrafish, described in a paper published online on June 18 by the American Journal of Physiology-Gastrointestinal and Liver Physiology. [More]
Nutrinia's NTRA-9620 granted FDA orphan drug designation for treatment of short bowel syndrome

Nutrinia's NTRA-9620 granted FDA orphan drug designation for treatment of short bowel syndrome

Nutrinia, developing therapies to treat rare gastrointestinal disorders, announced today that the U.S. Food and Drug Administration (FDA) granted orphan drug designation for the company's orally-administered drug for treating short bowel syndrome (SBS) in patients of all ages. Nutrinia plans to begin a pivotal clinical trial in this indication. [More]
NGS mutational testing can help detect patients with Barrett's esophagus

NGS mutational testing can help detect patients with Barrett's esophagus

Barrett's esophagus (BE) develops in a subset of patients with gastroesophageal reflux disease (GERD) and can increase the risk of developing cancer of the esophagus. Although periodic surveillance for cancer is recommended for BE patients, these examinations may fail to identify pre-cancerous dysplasia and early cancers. [More]
Mistakes in mismatch repair genes may accurately predict response to certain immunotherapy drugs

Mistakes in mismatch repair genes may accurately predict response to certain immunotherapy drugs

In a report of a proof-of-principle study of patients with colon and other cancers for whom standard therapies failed, researchers at the Johns Hopkins Kimmel Cancer Center say that mistakes in so-called mismatch repair genes, first identified by Johns Hopkins and other scientists two decades ago, may accurately predict who will respond to certain immunotherapy drugs known as PD-1 inhibitors. Such drugs aim to disarm systems developed by cancer cells to evade detection and destruction by immune system cells. [More]
Canadian government improves access to gluten-free diets to mark Celiac Awareness Month

Canadian government improves access to gluten-free diets to mark Celiac Awareness Month

To mark Celiac Awareness Month, the Honourable Rona Ambrose, Minister of Health today announced changes that will result in more safe food choices for Canadians with celiac disease by approving "gluten-free" claims on specially produced oats and foods containing these oats. [More]
Risk prediction model can help target hepatitis C treatment to patients with most urgent need

Risk prediction model can help target hepatitis C treatment to patients with most urgent need

A team of researchers at the University of Michigan Health System has developed a risk prediction model that helps identify which hepatitis C patients have the most urgent need for new anti-viral drugs. [More]
Patients want to take more active role in decision-making process, study finds

Patients want to take more active role in decision-making process, study finds

Patients faced with a choice of surgical options want to engage their physicians and take a more active role in decision-making, according to a study (abstract 567) released at Digestive Disease Week 2015. [More]
UCB sponsoring several presentations on Cimzia for Crohn's disease at DDW 2015

UCB sponsoring several presentations on Cimzia for Crohn's disease at DDW 2015

UCB, a global biopharmaceutical company focusing on immunology and neurology treatment and research, is sponsoring several data presentations on Cimzia (certolizumab pegol) at Digestive Disease Week 2015, taking place in Washington, DC from May 16-19. [More]
Conjoined twin boys undergo successful separation surgery

Conjoined twin boys undergo successful separation surgery

Carter and Conner, conjoined twin boys born Dec. 12, 2014, in Jacksonville, Fla., underwent a successful separation surgery on May 7, 2015. The 12-hour surgery was led by a team of highly skilled pediatric specialists that included Daniel Robie, MD, chief of pediatric general surgery, and Nicholas Poulos, MD, pediatric general surgeon, for Nemours Children's Specialty Care and Wolfson Children's Hospital. [More]
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