Smallpox News and Research

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Smallpox is a highly contagious disease caused by the variola virus, a member of the Orthopox virus family. It is one of the most devastating diseases known to humanity, with a mortality rate as high as 30%. In 1967, the World Health Organization embarked upon an intensified vaccination campaign to eliminate smallpox, which culminated in the successful eradication of the disease globally by 1980.

By the mid-1980s, there were only two known repositories of variola virus: the Institute of Virus Preparations in Russia, and the US CDC. The events in the US in September and October 2001 highlighted the risk that the variola virus might be used as an agent of bioterrorism. Governments around the world are taking precautionary measures to be ready to deal with a potential smallpox outbreak.
Immunological responses against monkeypox virus concerning the 2022 outbreak

Immunological responses against monkeypox virus concerning the 2022 outbreak

What are the eye complications associated with monkeypox infection?

What are the eye complications associated with monkeypox infection?

Phylodynamic analysis of the monkeypox virus genome suggests low genetic variation and evolutionary rates

Phylodynamic analysis of the monkeypox virus genome suggests low genetic variation and evolutionary rates

Specific mutations in the monkeypox virus contribute to its continued infectiousness

Specific mutations in the monkeypox virus contribute to its continued infectiousness

How does the ISG15/ISGylation system modulate Vaccinia virus infection?

How does the ISG15/ISGylation system modulate Vaccinia virus infection?

'What pediatricians need to know' about monkeypox in children

'What pediatricians need to know' about monkeypox in children

UC San Diego participates in national trial to assess potential treatment for human monkeypox

UC San Diego participates in national trial to assess potential treatment for human monkeypox

Researchers use models developed for COVID-19 predictions to predict and simulate monkeypox transmission and vaccination scenarios

Researchers use models developed for COVID-19 predictions to predict and simulate monkeypox transmission and vaccination scenarios

Monkeypox virus infection and its persistence in the testes of infected crab-eating macaques

Monkeypox virus infection and its persistence in the testes of infected crab-eating macaques

Review of characteristics of human monkeypox

Review of characteristics of human monkeypox

UK hospital study explores whether monkeypox can be transmitted through aerosolized droplets and fomites

UK hospital study explores whether monkeypox can be transmitted through aerosolized droplets and fomites

Mass General Brigham sites announce participation in phase 3 trial of monkeypox treatment

Mass General Brigham sites announce participation in phase 3 trial of monkeypox treatment

Bioinformatics analysis of monkeypox virus-host cell interactions

Bioinformatics analysis of monkeypox virus-host cell interactions

Scientists detect monkeypox virus in the testes of macaques during acute infection

Scientists detect monkeypox virus in the testes of macaques during acute infection

Clinical trial to evaluate antiviral drug for monkeypox begins in the Democratic Republic of the Congo

Clinical trial to evaluate antiviral drug for monkeypox begins in the Democratic Republic of the Congo

The role of wastewater surveillance for monitoring monkeypox

The role of wastewater surveillance for monitoring monkeypox

What is the impact of monkeypox infection on the hemostatic system?

What is the impact of monkeypox infection on the hemostatic system?

Myocarditis may be attributable to monkeypox infection

Myocarditis may be attributable to monkeypox infection

Study finds the majority of post-vaccination monkeypox infections occur within 2 weeks of receiving the first dose of MVA-BN

Study finds the majority of post-vaccination monkeypox infections occur within 2 weeks of receiving the first dose of MVA-BN

French study reports growing evidence of sexual activity-linked transmission of monkeypox

French study reports growing evidence of sexual activity-linked transmission of monkeypox

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