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Staphylococcus aureus is a spherical bacterium (coccus) which on microscopic examination appears in pairs, short chains, or bunched, grape-like clusters. These organisms are Gram-positive. Some strains are capable of producing a highly heat-stable protein toxin that causes illness in humans.
Researchers successfully use CRISPR to treat adult mouse model of Duchenne muscular dystrophy

Researchers successfully use CRISPR to treat adult mouse model of Duchenne muscular dystrophy

Researchers have used CRISPR to treat an adult mouse model of Duchenne muscular dystrophy. This marks the first time that CRISPR has successfully treated a genetic disease inside a fully developed living mammal with a strategy that has the potential to be translated to human therapy. [More]
Newly discovered molecular mechanism may provide alternative explanation for antibiotic resistance

Newly discovered molecular mechanism may provide alternative explanation for antibiotic resistance

The bacterium B. cereus had so far been considered to be exclusively endospore-forming. In response to harsh conditions, the bacteria form protective endospores enabling them to remain dormant for extended periods. When conditions are more favourable, the endospores reactivate to become fully functioning bacteria. [More]
Father-daughter duo co-author research paper on new grapefruit cybrids

Father-daughter duo co-author research paper on new grapefruit cybrids

When Jude Grosser's daughter, Melinda, was in elementary school, he would often take her to his laboratory at the University of Florida's Citrus Research and Education Center, where he works as a researcher on citrus diseases and creating new varieties. [More]
Drugs approved for various conditions also have antibiotic properties

Drugs approved for various conditions also have antibiotic properties

A number of drugs already approved to treat parasitic infections, cancers, infertility and other conditions also show promise as antibiotic agents against staph and tuberculosis infections, according to a new study by University of Illinois chemists and collaborators. Because these agents act against multiple targets within the bacteria, it may be harder for bacteria to develop resistance. [More]
New easy-to-use computer program can quickly identify drug-resistant infections

New easy-to-use computer program can quickly identify drug-resistant infections

Scientists have developed an easy-to-use computer program that can quickly analyse bacterial DNA from a patient's infection and predict which antibiotics will work, and which will fail due to drug resistance. The software is currently being trialled in three UK hospitals to see whether it could help speed up diagnosis of drug-resistant infections and enable doctors to better target the prescription of antibiotics. [More]
Novel class of antimicrobials could be effective in fighting drug-resistant MRSA infection

Novel class of antimicrobials could be effective in fighting drug-resistant MRSA infection

A novel class of antimicrobials that inhibits the function of a key disease-causing component of bacteria could be effective in fighting methicillin-resistant Staphylococcus aureus (MRSA), one of the major drug-resistant bacterial pathogens, according to researchers at Georgia State University. [More]
Innovative microbiome technology may help fight certain infections

Innovative microbiome technology may help fight certain infections

Stony Brook University and Ortek Therapeutics, Inc. announced today that two patent applications were filed in the United States and internationally for nutrient based compositions utilizing an innovative microbiome technology that may help combat certain infections. [More]
Coating implants with certain 'activator' can prevent S. aureus infection

Coating implants with certain 'activator' can prevent S. aureus infection

Biofilms frequently coat the surfaces of catheters, and of various medical implants and prostheses, where they can cause life-threatening infections. New research at the Sahlgrenska Academy show that coating implants with a certain "activator" can prevent Staphylococcus aureus, the leading cause of hospital-acquired infections, from forming biofilms. [More]
Some antibiotics may make MRSA more harmful

Some antibiotics may make MRSA more harmful

Treating MRSA with certain first-line antibiotics can actually make MRSA skin infections worse, according to a study published in Cell Host & Microbe. [More]
Certain antibiotic treatment for MRSA may potentially make patients sicker

Certain antibiotic treatment for MRSA may potentially make patients sicker

A new study sheds light on how treatment of the "superbug" known as MRSA with certain antibiotics can potentially make patients sicker. The findings by Cedars-Sinai scientists, published today in the journal Cell Host & Microbe, could have implications for managing the bug, a virulent form of the common staph infection that can be difficult to control. [More]
Common ingredient in sunscreen can prevent infections related to medical implants

Common ingredient in sunscreen can prevent infections related to medical implants

A common ingredient in sunscreen could be an effective antibacterial coating for medical implants such as pacemakers and replacement joints. [More]
Paratek initiates Omadacycline phase 3 clinical study in community acquired bacterial pneumonia (CABP)

Paratek initiates Omadacycline phase 3 clinical study in community acquired bacterial pneumonia (CABP)

Paratek Pharmaceuticals, Inc. has announced the dosing of the first patient in its Phase 3 clinical study of its lead drug candidate, omadacycline, for the treatment of Community Acquired Bacterial Pneumonia (CABP). This global Phase 3 study will assess the efficacy and safety of omadacycline compared with moxifloxacin in subjects with CABP. [More]
Key part of MRSA vaccine puzzle unearthed

Key part of MRSA vaccine puzzle unearthed

Immunologists from Trinity College Dublin have unearthed a key piece of the MRSA vaccine puzzle by identifying specific ‘helper’ cells whose role in the immune response is critical in affecting infection outcomes. [More]
Coating implants with tissue plasminogen activator can prevent biofilm-related infections

Coating implants with tissue plasminogen activator can prevent biofilm-related infections

Biofilms--mats of bacteria similar to the plaque that grows on teeth--frequently coat the surfaces of catheters, and of various medical implants and prostheses, where they can threaten lives or lead to failure of the implants. Antibiotics are impotent against biofilms. [More]
Tamoxifen drug clears MRSA, reduces mortality

Tamoxifen drug clears MRSA, reduces mortality

Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences have found that the breast cancer drug tamoxifen gives white blood cells a boost, better enabling them to respond to, ensnare and kill bacteria in laboratory experiments. Tamoxifen treatment in mice also enhances clearance of the antibiotic-resistant bacterial pathogen MRSA and reduces mortality. [More]
Allergan's anti-infective portfolio to be highlighted at IDWeek 2015

Allergan's anti-infective portfolio to be highlighted at IDWeek 2015

Allergan plc today announced that its infectious disease portfolio will be featured in 13 abstracts highlighting data at IDWeek 2015, which takes place from October 7-11, 2015, in San Diego. [More]
Cleaning patient rooms with combination of chemicals and UV light cuts transmission of superbugs

Cleaning patient rooms with combination of chemicals and UV light cuts transmission of superbugs

Healthcare facilities continue to battle drug-resistant organisms such as methicillin-resistant Staphylococcus aureus (MRSA) that loiter on surfaces even after patient rooms have been cleaned and can cause new, sometimes-deadly infections. [More]
Overall incidence of serious, highly drug-resistant group of bacteria relatively low in 2012-2013

Overall incidence of serious, highly drug-resistant group of bacteria relatively low in 2012-2013

The overall incidence in 2012-2013 was relatively low of a serious, highly drug-resistant group of bacteria (Carbapenem-resistant Enterobacteriaceae [CRE]) that are an important cause for health-care associated infections, according to a study published online by JAMA. Most CRE cases were associated with prior hospitalizations and discharge to long-term care settings. [More]
Plymouth University and Ingenza partner to develop efficient, scalable microbial production system for epidermicin

Plymouth University and Ingenza partner to develop efficient, scalable microbial production system for epidermicin

Ingenza is collaborating with researchers at Plymouth University to develop an efficient, scalable microbial production system for epidermicin, an exciting new antibiotic that rapidly kills methicillin-resistant Staphylococcus aureus and other harmful bacteria. [More]
Unlocking the genes behind antibiotic resistance: an interview with Professor Romesberg

Unlocking the genes behind antibiotic resistance: an interview with Professor Romesberg

Bacteria are very, very diverse. This is why their susceptibility to different antibiotics can be very different. It also makes the tools they have to evolve resistance in many cases different. [More]
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