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Staphylococcus aureus is a spherical bacterium (coccus) which on microscopic examination appears in pairs, short chains, or bunched, grape-like clusters. These organisms are Gram-positive. Some strains are capable of producing a highly heat-stable protein toxin that causes illness in humans.
Cigarette smoke promotes bacteria colonization, immune invasion

Cigarette smoke promotes bacteria colonization, immune invasion

The mouth is one of the "dirtiest" parts of the body, home to millions of germs. But puffing cigarettes can increase the likelihood that certain bacteria like Porphyromonas gingivalis will not only set up camp but will build a fortified city in the mouth and fight against the immune system. [More]
OIE’s new strategy aims to provide necessary tools to fight antimicrobial resistance more effectively

OIE’s new strategy aims to provide necessary tools to fight antimicrobial resistance more effectively

At the 84th General Session of the World Assembly of National Delegates, the OIE presented to its Members, and proposed for adoption, the basic principles of its new strategy to fight antimicrobial resistance. [More]
Natural product darwinolide may help combat fatal MRSA infection

Natural product darwinolide may help combat fatal MRSA infection

A serious and sometimes fatal bacterial infection, known as methicillin-resistant Staphylococcus aureus (MRSA), may soon be beatable thanks to the efforts of University of South Florida scientists who have isolated and tested an extract from a sponge found in Antarctica. [More]
Pathogen-selective approach to antibiotic development less disruptive to gut microbiome

Pathogen-selective approach to antibiotic development less disruptive to gut microbiome

St. Jude Children's Research Hospital scientists report the first evidence that a pathogen-specific antibiotic was less disruptive to the gut microbiome than broad-spectrum antibiotics. [More]
Study emphasizes benefits of newborn screening for CF patients

Study emphasizes benefits of newborn screening for CF patients

A new study led by a team from the Research Institute of the McGill University Health Centre and Cystic Fibrosis Canada reinforces the benefits of newborn screening for cystic fibrosis (CF) patients. [More]
Scientists identify novel way of synthesising promising new antibiotic

Scientists identify novel way of synthesising promising new antibiotic

A novel way of synthesising a promising new antibiotic has been identified by scientists at the University of Bristol. By expressing the genes involved in the production of pleuromutilin in a different type of fungus, the researchers were able to increase production by more than 2,000 per cent. [More]
Small doses of cancer drug may be potential treatment for sepsis and other pandemics

Small doses of cancer drug may be potential treatment for sepsis and other pandemics

Results from laboratory experiments and mouse studies suggest that small doses of drugs from a specific class of approved cancer medications called topoisomerase 1 (top1) inhibitors may protect against the overwhelming immune response to infection that sometimes leads to sepsis, a bacterial condition that kills as many as 500,000 people in the United States each year. [More]
Exposure to titanium dioxide nanoparticles increases bacterial infection of HeLa cells

Exposure to titanium dioxide nanoparticles increases bacterial infection of HeLa cells

When human cells are exposed to titanium dioxide without the presence of UV light from the sun, the risk for bacterial infection more than doubles. This finding by a Stony Brook University-led research team, published early online in the Journal of Nanobiotechnology, raises concerns about exposure to titanium dioxide, a nanoparticle commonly used in millions of products worldwide ranging from cosmetics to toothpaste, gum, food coloring, and medicines. [More]
Scientists evaluate phage-based therapy to battle antibiotic-resistant bacterial superbug infections

Scientists evaluate phage-based therapy to battle antibiotic-resistant bacterial superbug infections

Flinders University scientists are looking to bacteriophages – highly specific viruses - as the as the best way to attack antibiotic-resistant bacterial superbug infections. [More]
UC San Diego receives NIH grant to establish interdisciplinary center to combat antibiotic resistance

UC San Diego receives NIH grant to establish interdisciplinary center to combat antibiotic resistance

Researchers at University of California, San Diego School of Medicine have received a five-year, $9.5-million award from the National Institute of Allergy and Infectious Diseases at the National Institutes of Health to establish an interdisciplinary center to define the systems biology of antibiotic resistance. The program will be led by Bernhard Palsson, PhD, Distinguished Professor of Bioengineering and Pediatrics, and Victor Nizet, MD, professor of pediatrics and pharmacy. [More]
Novel biochemical method can extend lifetime of implantable medical devices

Novel biochemical method can extend lifetime of implantable medical devices

Blood-contacting implantable medical devices, such as stents, heart valves, ventricular assist devices, and extracorporeal support systems, as well as vascular grafts and access catheters, are used worldwide to improve patients' lives. However, these devices are prone to failure due to the body's responses at the blood-material interface; clots can form and inflammatory reactions can prevent the device from performing as indicated. Currently, when this occurs, the only solution is to replace the device. [More]
Novel antibiotics to overcome antibacterial resistance

Novel antibiotics to overcome antibacterial resistance

Small and innovative pharmaceutical companies, with products in early stages of development, presented some of their novel approaches and antimicrobial therapies under development during a dedicated session at the annual congress (ECCMID) of the European Society of Clinical Microbiology and Infectious Diseases(ESCMID) in Amsterdam. [More]
Keynotes announced for ECCMID 2016

Keynotes announced for ECCMID 2016

The European Society of Clinical Microbiology and Infectious Diseases (ESCMID) previews some of the keynote lectures at the 26th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). The globe’s most prominent infection specialists will be gathering at its annual congress in Amsterdam from 9 – 12 April 2016. [More]
Novel method uses light-activated nanodrug to help fight antibiotic-resistant infections

Novel method uses light-activated nanodrug to help fight antibiotic-resistant infections

A research team led by University of Arkansas chemist Jingyi Chen and University of Arkansas for Medical Sciences microbiologist Mark Smeltzer has developed an alternative therapeutic approach to fighting antibiotic-resistant infections. [More]
Study provides better picture of molecular basis for antibiotic resistance

Study provides better picture of molecular basis for antibiotic resistance

Scientists from the University of Leeds have solved a 25-year-old question about how a family of proteins allow bacteria to resist the effects of certain antibiotics. [More]
UCLA study finds better method to improve recovery, reduce spread of MRSA infection

UCLA study finds better method to improve recovery, reduce spread of MRSA infection

UCLA researchers have found that doctors can use a specific antibiotic in addition to surgically draining an abscess to give people a better chance of recovery. The discovery turns on its head the long-held notion that surgical drainage alone is sufficient for treating abscesses. [More]
Anti-bacterial fabrics show promise against superbugs

Anti-bacterial fabrics show promise against superbugs

Antibiotics have proven to be a valuable weapon in the fight against infectious bacteria. However, due to the excess use of antibiotics in conventional treatments, overtime antibiotics have become less effective. [More]
New research shows copper can destroy MRSA in touch contamination

New research shows copper can destroy MRSA in touch contamination

New research from the University of Southampton shows that copper can destroy MRSA spread by touching and fingertip contamination of surfaces. [More]
Allergan's sNDA for TEFLARO (ceftaroline fosamil) accepted by FDA

Allergan's sNDA for TEFLARO (ceftaroline fosamil) accepted by FDA

Allergan plc today announced the U.S. Food and Drug Administration has accepted for filing the company's supplemental New Drug Application (sNDA) for TEFLARO (ceftaroline fosamil). [More]
Discovery takes researchers one step closer to preventing C. diff

Discovery takes researchers one step closer to preventing C. diff

Exposure to specific antibiotics is linked to the development of certain strains of antibiotic-resistant C. difficile, one of the fastest growing bacteria superbugs, according to a new study published by Stuart Johnson, MD, of Loyola University Health System, Loyola University Chicago Stritch School of Medicine and the Hines VA Medical Hospital. [More]
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