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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Stem cells are distinguished from other cell types by two important characteristics. First, they are unspecialized cells capable of renewing themselves through cell division, sometimes after long periods of inactivity. Second, under certain physiologic or experimental conditions, they can be induced to become tissue- or organ-specific cells with special functions. In some organs, such as the gut and bone marrow, stem cells regularly divide to repair and replace worn out or damaged tissues. In other organs, however, such as the pancreas and the heart, stem cells only divide under special conditions.
WideCells signs LOI with Qigenix to undertake research at Manchester stem cell facility

WideCells signs LOI with Qigenix to undertake research at Manchester stem cell facility

WideCells Group PLC, the healthcare services company focused on providing stem cell banking services and ground breaking insurance for stem cell treatment, is pleased to announce that it has taken steps to secure a new revenue stream, in addition to the cash flow opportunities outlined in the Company’s prospectus published in July this year, having signed a Letter of Intent (‘LOI’) with Qigenix and its CEO, Dr. Todd Ovokaitys. [More]
UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Previous studies identified the Hippo pathway kinases LATS1/2 as a tumor suppressor, but new research led by University of California San Diego School of Medicine scientists reveals a surprising role for these enzymes in subduing cancer immunity. The findings, published in Cell on December 1, could have a clinical role in improving efficiency of immunotherapy drugs. [More]
Study compares cardiac repair potential of three types of stem cells

Study compares cardiac repair potential of three types of stem cells

New research from New Zealand's University of Otago is providing fresh insights into how a patient's adult stem cells could best be used to regenerate their diseased hearts. [More]
Preventative strategy in stem cell transplant recipients may help thwart C. diff infections

Preventative strategy in stem cell transplant recipients may help thwart C. diff infections

It may be possible to safely prevent one of the most common - and costly to treat - infections contracted by hospitalized patients undergoing bone marrow transplantation for the treatment of blood cancers, according to a study from the Abramson Cancer Center at the University of Pennsylvania. [More]
Researchers reveal mechanism for side effects of drug used for treating hematological malignancies

Researchers reveal mechanism for side effects of drug used for treating hematological malignancies

A team of Japanese researchers revealed the mechanism for side effects such as fever and bone pain caused by G-CSF, which is widely used for peripheral blood hematopoietic stem cell harvesting (PBSCH). [More]
Transcription factor Nanog plays key role in reproduction of embryonic stem cells

Transcription factor Nanog plays key role in reproduction of embryonic stem cells

The transcription factor Nanog plays a crucial role in the self-renewal of embryonic stem cells. [More]
Sheffield haematologist wins prestigious Anthony Nolan Supporter Award

Sheffield haematologist wins prestigious Anthony Nolan Supporter Award

Professor John Snowden, Consultant Haematologist at Sheffield Teaching Hospitals NHS Foundation Trust, was presented with a national award by the blood cancer charity Anthony Nolan. [More]
Research identifies presence of neuron-producing stem cells in meninges

Research identifies presence of neuron-producing stem cells in meninges

A multidisciplinary research, conceived by Dr. Francesco Bifari, Department of Medical Biotechnology and Translational Medicine, University of Milan, Italy and Dr. Ilaria Decimo University of Verona, Italy, found that meninges - the protective membranes that enclose the brain - contain of a pool of neural stem cells. [More]
Research shows mechanism that induces heart arrhythmias in diabetic mice

Research shows mechanism that induces heart arrhythmias in diabetic mice

One of the most serious complications of diabetes, heart arrhythmias, is now on its way to be prevented and combated. [More]
New ULB study shows how cancer cell of origin controls malignant transition

New ULB study shows how cancer cell of origin controls malignant transition

Researchers at the Université libre de Bruxelles, ULB define for the first time how the cancer cell of origin controls invasive and metastatic properties of tumor cells. [More]
Low-dose chemotherapy regimens may be more effective at treating certain breast and pancreatic cancer types

Low-dose chemotherapy regimens may be more effective at treating certain breast and pancreatic cancer types

Conventional, high-dose chemotherapy treatments can cause the fibroblast cells surrounding tumors to secrete proteins that promote the tumors' recurrence in more aggressive forms, researchers at Taipei Medical University and the National Institute of Cancer Research in Taiwan and University of California, San Francisco, have discovered. [More]
Researchers uncover neural progenitors in protective membranes covering the brain

Researchers uncover neural progenitors in protective membranes covering the brain

In a cross-domain study directed by professor Peter Carmeliet (VIB - KU Leuven), researchers discovered unexpected cells in the protective membranes that enclose the brain, the so called meninges. [More]
HSCI researchers use color tagging system to track development of blood stem cells

HSCI researchers use color tagging system to track development of blood stem cells

Harvard Stem Cell Institute (HSCI) researchers have used a colorful, cell-labeling technique to track the development of the blood system and trace the lineage of adult blood cells travelling through the vast networks of veins, arteries, and capillaries back to their parent stem cell in the marrow. [More]
Biologists create bright red fluorescent protein to track essential cellular processes

Biologists create bright red fluorescent protein to track essential cellular processes

After years of trying, biologists have succeeded in creating an extremely bright red fluorescent protein in the lab. [More]
New color-coding tool sheds light on blood disorders, cancers by tracking clonal stem cells

New color-coding tool sheds light on blood disorders, cancers by tracking clonal stem cells

A new color-coding tool is enabling scientists to better track live blood stem cells over time, a key part of understanding how blood disorders and cancers like leukemia arise, report researchers in Boston Children's Hospital's Stem Cell Research Program. [More]
MEMOIR can help read history and ‘family trees’ of cells

MEMOIR can help read history and ‘family trees’ of cells

Researchers have developed a new method for reading the history and "family trees" of cells. [More]
Scientists map reorganization of genetic material in cells using 3-D imaging technique

Scientists map reorganization of genetic material in cells using 3-D imaging technique

Scientists have mapped the reorganization of genetic material that takes place when a stem cell matures into a nerve cell. [More]
Researchers identify pathway that helps cancer cells to aggressively spread in the brain

Researchers identify pathway that helps cancer cells to aggressively spread in the brain

Glioblastoma multiforme remains the most common and highly lethal brain cancer and is known for its ability to relapse. [More]
Creating artery banks may transform treatment of heart and vascular ailments

Creating artery banks may transform treatment of heart and vascular ailments

The prospect of creating artery "banks" available for cardiovascular surgery, bypassing the need to harvest vessels from the patient, could transform treatment of many common heart and vascular ailments. [More]
Lonza’s RAFT 3D Cell Culture System helps researchers develop corneal models for research into blindness treatment

Lonza’s RAFT 3D Cell Culture System helps researchers develop corneal models for research into blindness treatment

Lonza’s RAFT 3D Cell Culture System has been used to develop corneal models for research into treatment for a painful and potentially blinding corneal disease. [More]
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