29. October 2009 01:00
A recent study by Swedish researchers found that rheumatoid arthritis (RA) patients did not experience an elevated cancer risk in the first 6 years after starting anti-tumor necrosis factor (TNF) therapy.
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Posted in: Medical Condition News | Pharmaceutical News
Tags: Adalimumab, Arthritis, Autoimmune Disease, Cancer, Etanercept, Hospital, Infliximab, Methotrexate, Rheumatism, Rheumatoid Arthritis, Rheumatology, TNF Blockers
28. October 2009 08:22
According to new results from the WELCOME trial, exploratory data analyzing the impact of treatment with CIMZIA(®) (certolizumab pegol) - the only PEGylated anti-TNF (alpha) (Tumor Necrosis Factor alpha) - administered either every two weeks or every four weeks, showed that the majority of Crohn's disease patients in both dosing groups experienced no hospitalizations and surgical procedures during the course of the 26-week study.
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Posted in: Drug Trial News | Medical Condition News
Tags: Abatacept, Anemia, Angioedema, Antibody, Arthralgia, Arthritis, Autoimmune Disease, Cancer, Congestive Heart Failure, Crohn's Disease, Dyspnea, Exercise, Gastroenterology, Headache, Heart Failure, Hepatitis B, Hospital, Hypersensitivity, Immunology, Inflammatory Bowel Disease, Infliximab, Leukopenia, Listeriosis, Lupus, Lymphoma, Melanoma, Methotrexate, Nausea, Nervous System, Neuropathy, Rheumatoid Arthritis, Rituximab, Sepsis, Skin Cancer, Thrombocytopenia, TNF Blockers, Tuberculosis, Ulcerative Colitis, Urticaria, Virus, Vomiting
27. October 2009 05:04
New data from an open-label extension study evaluating the long-term safety and efficacy of CIMZIA® (certolizumab pegol) in moderate to severe Crohn's disease patients demonstrate that 82 percent of patients actively treated with CIMZIA - the only PEGylated anti-TNF-alpha (Tumor Necrosis Factor alpha) - remained in long-term remission without dose escalation up to 3.5 years.
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Posted in: Drug Trial News | Disease/Infection News
Tags: Abatacept, Abdominal Pain, Anemia, Angioedema, Antibody, Arthritis, Autoimmune Disease, Cancer, Congestive Heart Failure, Cough, Crohn's Disease, Dyspnea, Exercise, Gastroenterology, Headache, Heart Failure, Hepatitis B, Hypersensitivity, Immunology, Inflammatory Bowel Disease, Leukopenia, Listeriosis, Lupus, Lymphoma, Melanoma, Methotrexate, Nervous System, Neuropathy, Pneumonia, Rheumatoid Arthritis, Rituximab, Sepsis, Skin Cancer, Thrombocytopenia, TNF Blockers, Tuberculosis, Ulcerative Colitis, Urticaria, Virus
20. October 2009 05:35
Phase 3 data reported for the first time show that once every four week subcutaneous injections of SIMPONI(TM) (golimumab) resulted in significantly greater inhibition of structural damage compared with placebo plus methotrexate in patients with active rheumatoid arthritis (RA) and active psoriatic arthritis (PsA).
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Posted in: Drug Trial News | Medical Condition News
Tags: Abatacept, Allergy, Ankylosing Spondylitis, Antibody, Arthritis, Basal Cell Carcinoma, Blood Pressure, Bone, Breast Cancer, Bronchitis, Cancer, Cartilage, Cell, Cold Sores, Cough, Diabetes, Diarrhea, Education, Golimumab, Heart Failure, Hepatitis B, Hodgkin's Disease, Immunology, Inflammatory Disease, Lung Cancer, Lupus, Lymphoma, Methotrexate, Monoclonal Antibody, Multiple Sclerosis, Nausea, Nephrology, Nervous System, Oncology, Psoriasis, Psoriatic Arthritis, Rheumatoid Arthritis, Rheumatology, Rituximab, Sepsis, Skin Cancer, Squamous Cell Carcinoma, TNF Blockers, Tuberculosis, Vaccine, Virus, Vomiting, Weight Loss
19. October 2009 23:55
UCB today announced data that showed rapid and sustained improvements in ACR20, physical function, pain and fatigue of rheumatoid arthritis (RA) as early as the first week, and inhibition of progression of structural joint damage (seen at week 24) following treatment with Cimzia (certolizumab pegol), together with methotrexate (MTX), was sustained up to 100 weeks.
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Posted in: Drug Trial News | Medical Condition News
Tags: Abatacept, Anemia, Angioedema, Antibody, Anti-Inflammatory, Arthralgia, Arthritis, Autoimmune Disease, Back Pain, Bone, Bronchitis, Cancer, Congestive Heart Failure, Crohn's Disease, Dyspnea, Exercise, Headache, Heart Failure, Hepatitis B, Hospital, Hypersensitivity, Immunology, Leukopenia, Listeriosis, Lupus, Lymphoma, Melanoma, Methotrexate, Nervous System, Neuropathy, Rheumatoid Arthritis, Rheumatology, Rituximab, Sepsis, Skin Cancer, Thrombocytopenia, TNF Blockers, Tuberculosis, Urinary Tract Infection, Urticaria, Virus
19. October 2009 09:41
New long-term data from two pivotal, Phase 3 clinical trials showed that patients with active rheumatoid arthritis (RA) receiving SIMPONI(TM) (golimumab) every four weeks achieved sustained improvements in signs and symptoms and physical function response through one year. These new data were presented today at the 2009 American College of Rheumatology (ACR) Annual Scientific Meeting.
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Posted in: Drug Trial News | Medical Condition News
Tags: Adalimumab, Ankylosing Spondylitis, Antibody, Arthritis, Blood Pressure, Breast Cancer, Bronchitis, Cancer, Cartilage, Cell, Cold Sores, Cough, Diabetes, Diarrhea, Education, Etanercept, Golimumab, Heart Failure, Hepatitis B, Hygiene, Immunology, Infliximab, Lupus, Lymphoma, Methotrexate, Monoclonal Antibody, Multiple Sclerosis, Nausea, Nephrology, Nervous System, Oncology, Psoriatic Arthritis, Rheumatoid Arthritis, Rheumatology, TNF Blockers, Tuberculosis, Vaccine, Virus, Vomiting, Weight Loss
1. September 2009 06:41
UCB Canada Inc. announced today that Health Canada has approved Cimzia, the only PEGylated anti-TNF (Tumor Necrosis Factor), for the treatment of adult patients with moderately to severely active rheumatoid arthritis (RA).
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c1be306d-a0a9-4d00-9b96-0ac6eca3c5e4|0|.0
Posted in: Drug Trial News | Pharmaceutical News
Tags: Abatacept, Anemia, Angioedema, Arthritis, Basal Cell Carcinoma, Cell, Congestive Heart Failure, Dyspnea, Exercise, Heart Failure, Hepatitis B, Herpes, Hospital, Hypersensitivity, Immunology, Leukopenia, Listeriosis, Lupus, Lymphoma, Melanoma, Methotrexate, Nervous System, Neuropathy, Prophylaxis, Rheumatoid Arthritis, Sepsis, Thrombocytopenia, TNF Blockers, Tuberculosis, Urticaria, Virus
9. August 2009 20:03
Lloyd J. Old, M.D., is Director of the Ludwig Institute for Cancer Research (LICR) New York Branch. He is also Director of the Cancer Research Institute (CRI) Scientific Advisory Council, Director of the CRI/LICR Cancer Vaccine Collaborative, and Director of the CRI Cancer Vaccine Consortium. He has been a Member of the National Academy of Sciences since 1978.
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28. June 2009 21:37
Golimumab, a new tumour necrosis factor-α (TNF-α) inhibitor reduces the signs and symptoms of rheumatoid arthritis in patients who have previously received any other TNF-α inhibitor, and might be a good option for patients who have inadequate responses to one or two other TNF-α inhibitors, finds an Article published Online first and in this week's edition of The Lancet.
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28. June 2009 21:01
Roche has announced that it has submitted a combined filing to the European health authorities (the European Medicines Agency) for three new indications to extend the label for MabThera to use as a first-line biologic therapy for patients with rheumatoid arthritis (RA).
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20. May 2009 02:16
Genentech, Inc. and Biogen Idec today announced that the companies submitted two supplemental Biologics License Applications (sBLAs) to the U.S. Food and Drug Administration (FDA) for Rituxan (rituximab) plus standard chemotherapy for people with previously untreated or treated chronic lymphocytic leukemia (CLL).
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19. May 2009 16:50
Researchers in London have demonstrated the ability of adult stem cells from bone marrow (mesenchymal stem cells, or MSCs) to deliver a cancer-killing protein to tumors.
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13. May 2009 23:11
UCB announced today that the U.S. Food and Drug Administration (FDA) approved Cimzia, the only PEGylated anti-TNF (Tumor Necrosis Factor), for the treatment of adult patients with moderately to severely active rheumatoid arthritis (RA).
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3888905d-1599-4bf4-a85e-aa48bed64502|2|3.0
Posted in: Pharmaceutical News
Tags: Abatacept, Anemia, Angioedema, Antibody, Antimicrobial Drug, Arthralgia, Arthritis, Autoimmune Disease, Bronchitis, Cimzia (Certolizumab pegol), Congestive Heart Failure, Corticosteroid, Crohn's Disease, Dyspnea, Heart Failure, Hepatitis B, Hypertension (High Blood Pressure), Leukopenia, Listeriosis, Lupus, Lymphoma, Methotrexate, Neuropathy, Peripheral Neuropathy, Rheumatoid Arthritis, Rituximab, TNF Blockers, Urinary Tract Infection, Virotherapy, Virus
29. April 2009 23:49
Differing biological response to infection between men and women may explain higher death rates among older men who are hospitalized with community-acquired pneumonia (CAP).
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20. April 2009 23:15
Overexpression of PEA-15, which binds and drags an oncoprotein out of the cell nucleus where it fuels cancer growth, steeply reduced breast cancer tumors in a preclinical experiment, researchers at The University of Texas M. D. Anderson Cancer Center reported at the 100th annual meeting of the American Association for Cancer Research.
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960e8386-86fb-48bc-b2e4-866e76266ef6|0|.0
Posted in: Medical Research News
Tags: Apoptosis, Autophagy, Biologics Drug / Agent, Breast Cancer, Cancer, DNA, Gene Therapy, Genetics, Glucose Metabolism, Metabolism, Oncology, Ovarian Cancer, TNF Blockers