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A telomere is a region of repetitive DNA at the end of a chromosome, which protects the end of the chromosome from deterioration.
Higher maternal age of successful child bearing may be marker of healthy aging

Higher maternal age of successful child bearing may be marker of healthy aging

Death and taxes have long been said to be the only two things guaranteed in life. Exactly when someone will die, in most instances, remains a mystery. [More]
Starvation may shorten lifespans of children and male descendants, study suggests

Starvation may shorten lifespans of children and male descendants, study suggests

New Tel Aviv University research suggests that periods of fasting or starvation may significantly shorten the lifespans of both children and their male descendants. [More]
Genetic differences between brain cancer cells and normal tissues could offer clues to tumor behavior

Genetic differences between brain cancer cells and normal tissues could offer clues to tumor behavior

Two recently discovered genetic differences between brain cancer cells and normal tissue cells -- an altered gene and a snippet of noncoding genetic material -- could offer clues to tumor behavior and potential new targets for therapy, Johns Hopkins scientists report. [More]
Length of telomeres may reveal if vitamin D and omega-3 supplements improve heart health, longevity

Length of telomeres may reveal if vitamin D and omega-3 supplements improve heart health, longevity

The length of your telomeres appears to be a window into your heart health and longevity, and scientists are measuring them to see if vitamin D and omega-3 supplements really improve both. [More]
UPCI scientists reveal how cancer cells hijack DNA repair pathways to stay alive

UPCI scientists reveal how cancer cells hijack DNA repair pathways to stay alive

Research by scientists at the University of Pittsburgh Cancer Institute has revealed how cancer cells hijack DNA repair pathways to prevent telomeres, the endcaps of chromosomes, from shortening, thus allowing the tumor to spread. The findings are published today in the journal Cell Reports. [More]
Study suggests targeting UNG enzyme may help treat non-Hodgkin's lymphoma

Study suggests targeting UNG enzyme may help treat non-Hodgkin's lymphoma

Researchers have discovered that an enzyme called uracil-DNA glycosylase (UNG) protects the ends of B cell chromosomes to facilitate the proliferation of these antibody-producing cells in response to infection. [More]
Increased food availability during active season slows cellular aging in animals

Increased food availability during active season slows cellular aging in animals

Hibernation has long been considered the secret behind the relatively long lifespan of the edible dormouse. [More]
Nobel laureate-led study uses new technology to watch interaction between telomerase and telomeres

Nobel laureate-led study uses new technology to watch interaction between telomerase and telomeres

As the rope of a chromosomes replicates, it frays at the ends. No problem: A chromosome's ends have extra twine so that fraying doesn't reach into the body of the rope where the important information resides. [More]
Penn researchers uncover strategy to reverse effects of dyskeratosis congenita

Penn researchers uncover strategy to reverse effects of dyskeratosis congenita

Dyskeratosis congenita, or DC, is a rare, inherited disease for which there are limited treatment options and no cure. [More]
Study reveals crucial role of TERRA in preservation of telomeres

Study reveals crucial role of TERRA in preservation of telomeres

Despite their especially compact structure that is difficult to access, telomeres transcribe information like the rest of the DNA. [More]
New disease gene linked to shortened telomeres appears to raise risk of pulmonary fibrosis-emphysema

New disease gene linked to shortened telomeres appears to raise risk of pulmonary fibrosis-emphysema

Johns Hopkins researchers say they have identified a new disease gene that, when mutated, appears to increase the risk in a small number of people of developing emphysema and a lung-scarring condition known as pulmonary fibrosis. [More]
Male hormones can reverse biological drivers of aging, study shows

Male hormones can reverse biological drivers of aging, study shows

Telomerase, an enzyme naturally found in the human organism, is the closest of all known substances to a "cellular elixir of youth." In a recent study, Brazilian and US researchers show that sex hormones can stimulate production of this enzyme. [More]
Mutations in STN1 gene cause Coats plus syndrome

Mutations in STN1 gene cause Coats plus syndrome

A team of Israeli researchers has discovered that mutations in STN1, a gene that helps maintain the ends of chromosomes, cause the rare, inherited disorder Coats plus syndrome. [More]
Review highlights interconnected roles of apoptosis, cellular senescence in cancer and aging

Review highlights interconnected roles of apoptosis, cellular senescence in cancer and aging

A common feature of cancer and aging is cells' reduced ability to respond to stress-induced damage to DNA or cellular structures. [More]
Scientists discover new way to predict risk for delayed recovery in children with AML

Scientists discover new way to predict risk for delayed recovery in children with AML

The chemotherapy treatments necessary to treat Acute Myeloid Leukemia (AML) in children can be grueling on the body, and can cause health-related complications during therapy, as well as long down the road after remission. [More]
Scientists develop new nonradioactive method to determine telomere length

Scientists develop new nonradioactive method to determine telomere length

UT Southwestern Medical Center cell biologists have identified a new method for determining the length of telomeres, the endcaps of chromosomes, which can influence cancer progression and aging. [More]
Maternal stress exposure can have major effect on child’s development and future health

Maternal stress exposure can have major effect on child’s development and future health

The environment the unborn child is exposed to inside the womb can have a major effect on her or his development and future health. Maternal stress during pregnancy can be transmitted biologically to the unborn child. [More]
Maintaining cardiomyocyte telomere length may enhance heart regeneration in adults

Maintaining cardiomyocyte telomere length may enhance heart regeneration in adults

Researchers at the Spanish National Center for Cardiovascular Research have discovered that the ends of heart muscle cell chromosomes rapidly erode after birth, limiting the cells' ability to proliferate and replace damaged heart tissue. [More]
TSRI study shows how specific gene mutation promotes growth of aggressive tumors

TSRI study shows how specific gene mutation promotes growth of aggressive tumors

Scientists at The Scripps Research Institute have caught a cancer-causing mutation in the act. A new study shows how a gene mutation found in several human cancers, including leukemia, gliomas and melanoma, promotes the growth of aggressive tumors. [More]
First breakthrough in gene therapy against aging

First breakthrough in gene therapy against aging

In September 2015, then 44 year-old CEO of BioViva USA Inc. Elizabeth Parrish received two of her own company's experimental gene therapies: one to protect against loss of muscle mass with age, another to battle stem cell depletion responsible for diverse age-related diseases and infirmities. [More]
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