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Emotionally abused children may face accelerated cellular aging as adults

21. November 2009 00:51
Children who suffer physical or emotional abuse may be faced with accelerated cellular aging as adults, according to new research from Butler Hospital and Brown University. [More]

Posted in: Child Health News | Medical Science News

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Researchers find link between telomeres and longevity

12. November 2009 00:32
A team led by researchers at Albert Einstein College of Medicine of Yeshiva University has found a clear link between living to 100 and inheriting a hyperactive version of an enzyme that rebuilds telomeres - the tip ends of chromosomes. The findings appear in the latest issue of the Proceedings of the National Academy of Sciences. [More]

Cellular mechanisms that may impact immune functions in the elderly discovered

9. November 2009 03:15
Investigators discover cellular mechanisms that may impact the decline of both innate and adaptive immune functions that increase the susceptibility to various infectious agents, cancer and diseases in the elderly say experts at the annual meeting of the American College of Allergy, Asthma and Immunology (ACAAI) in Miami Beach, Fla. [More]

DKC establishes link between genetic mutation affecting telomerase function and human disease

19. October 2009 04:49
The human genetic disease dyskeratosis congenita (DKC) is an autosomal dominant disease that leads to abnormalities in tissues with a rapid cell turnover - the skin, nails, bone marrow, lungs and gut. Patients with DKC experience life-threatening symptoms. Bone marrow failure increases their risk of fatal infections and cancer. Many die before the age of 30 and management of the disease is limited to trying to treat its symptoms. [More]

Posted in: Medical Science News | Medical Condition News

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National Science Foundation funded 2009 Nobel laureates felicitated

15. October 2009 07:28
The National Science Foundation (NSF) congratulates the 2009 Nobel laureates, particularly those who have received NSF funding over the years: Jack W. Szostak, who shared the prize in physiology or medicine; Thomas A. Steitz, who shared the prize in chemistry; and Elinor Ostrom and Oliver E. Williamson who earned the Sveriges Riksbank Prize in economic sciences in memory of Alfred Nobel 2009. [More]

Posted in: Miscellaneous News

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Molecular biologist receives 2009 Nobel Prize in Physiology or Medicine

6. October 2009 02:21
Molecular biologist Elizabeth H. Blackburn, PhD, 60, of the University of California, San Francisco, today was named to receive the 2009 Nobel Prize in Physiology or Medicine. [More]

Research reveals that large non-coding RNA in mammals play an important role in telomere maintenance

1. September 2009 04:09
A team of researchers from The Wistar Institute have shown that a large non-coding RNA in mammals and yeast plays a central role in helping maintain telomeres, the tips of chromosomes that contain important genetic information and help regulate cell division. Since this RNA also facilitates the formation of DNA at telomeres-a process that can protect aging cells and destabilize tumor cells-manipulating its expression may be useful in treating cancer and other diseases. [More]

Posted in: Medical Science News

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Protein plays unexpected role protecting chromosome tips

13. August 2009 19:43
A protein specialist that opens the genomic door for DNA repair and gene expression also turns out to be a multi-tasking workhorse that protects the tips of chromosomes and dabbles in a protein-destruction complex, a team lead by researchers at The University of Texas M. D. Anderson Cancer Center reports in the Aug. 13 edition of Molecular Cell. [More]

Handle with care: Telomeres resemble DNA fragile sites

9. July 2009 17:52
Telomeres, the repetitive sequences of DNA at the ends of linear chromosomes, have an important function: They protect vulnerable chromosome ends from molecular attack. [More]

Posted in: Medical Research News

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Study gives clues to how ultra-rare adrenocortical cancer forms

4. June 2009 19:49
At the ends of chromosome are special pieces of DNA called telomeres. Think of it as the little tip that caps off a shoelace. The telomeres send signals to the cells to let them know it's the end point, not a break that should be repaired. [More]

Posted in: Medical Research News

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Researchers target telomeres to attack tumors

5. May 2009 19:09
Hoping to develop more effective long-term attacks on cancer, researchers at the Indiana University School of Medicine are conducting the first human tests of a breast cancer drug regimen that includes a compound meant to force cancer cells to grow old and die. [More]

African sleeping sickness parasite breaks its own DNA to avoid detection

15. April 2009 21:58
The parasite Trypanosoma brucei, which causes African sleeping sickness, is like a thief donning a disguise. [More]

Posted in: Medical Science News

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The egg makes sure that sperm don't get too old

25. March 2009 19:16
In contrast to women, men are fertile throughout life, but research at the Sahlgrenska Academy, University of Gothenburg, Sweden, has now shown that a fertilising sperm can get help from the egg to rejuvenate. The result is an important step towards future stem cell therapy. [More]

Posted in: Medical Research News

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Study reinforces the importance of healthy living for women

16. March 2009 18:44
Women who maintain a healthy weight and who have lower perceived stress may be less likely to have chromosome changes associated with aging than obese and stressed women, according to a pilot study that was part of the Sister Study. [More]

Enhanced skin cancer risk linked to defects in cellular aging controls

23. February 2009 22:18
Cell lifespan is limited by telomeres, DNA sequences that cap chromosomes and control the number of times a cell may be copied. [More]

Posted in: Medical Research News

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