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Tetanus is a severe, frequently fatal disease caused by an exotoxin produced by Clostridium tetani, a bacterium that is found in the environment. Tetanus is not transmitted from person to person. Rather, Clostridium tetani enters the body through an open wound, including lacerations, abrasions and puncture wounds. The toxin causes neuromuscular dysfunction, with rigidity and spasms of skeletal muscles. The muscle spasms usually start in the jaw (which is why the disease is sometimes called "lockjaw") and neck and may spread to many other muscles, leading to generalized paralysis.
Ralphs Pharmacies continue to offer Tdap vaccinations for whooping cough in Southern California

Ralphs Pharmacies continue to offer Tdap vaccinations for whooping cough in Southern California

As the number of pertussis cases, also known as whooping cough, reaches epidemic proportions in California, Ralphs Pharmacies continue to offer Tdap (tetanus, diphtheria, pertussis) vaccinations at its 85 in-store pharmacies throughout Southern California. [More]
Studies confirm importance of men seeing physician on regular basis

Studies confirm importance of men seeing physician on regular basis

For many men being a father is about staying strong as they protect and care for their family. Some men see going to the doctor as a weakness or nuisance, but protecting your health is one of the best things a father can do for his family. [More]
Sanofi presents Phase II trial results for investigational vaccine for prevention of CDI

Sanofi presents Phase II trial results for investigational vaccine for prevention of CDI

Sanofi Pasteur, the vaccines division of Sanofi, presented Phase II (H-030-012) trial results for an investigational vaccine for the prevention of Clostridium difficile infection at the 114th General Meeting of the American Society for Microbiology. [More]
Pfizer reports positive results from rLP2086 Phase 2 study for invasive meningococcal disease

Pfizer reports positive results from rLP2086 Phase 2 study for invasive meningococcal disease

Pfizer Inc. announced today the results from two Phase 2 studies of bivalent rLP2086, Pfizer's recombinant vaccine candidate, currently under development for the prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroup B in 10 to 25 year olds. [More]
MinuteClinic walk-in medical clinics open in central Georgia

MinuteClinic walk-in medical clinics open in central Georgia

The first MinuteClinic walk-in medical clinics in central Georgia have opened inside two CVS/pharmacy stores in Macon and one in Warner Robbins. [More]
Rates of infant immunization with pertussis-containing vaccine do not increase with epidemic

Rates of infant immunization with pertussis-containing vaccine do not increase with epidemic

Conventional wisdom holds that when the risk of catching a disease is high, people are more likely to get vaccinated to protect themselves. [More]
Research provides definitive evidence of safety of Tdap immunization during pregnancy

Research provides definitive evidence of safety of Tdap immunization during pregnancy

A preliminary study finds that receipt of the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine in the third trimester of pregnancy did not increase the risk of adverse events for the mother or infant, according to a study in the May 7 issue of JAMA, a theme issue on child health. [More]
Promising new approach targets cancer protein to slow tumor growth

Promising new approach targets cancer protein to slow tumor growth

Sometimes a full-on assault isn't the best approach when dealing with a powerful enemy. A more effective approach, in the long run, may be to target the support system replenishing the supplies that keep your foe strong and ready for battle. [More]
Doctors must consider factors when administering combination vaccines, say researchers

Doctors must consider factors when administering combination vaccines, say researchers

One of the most popular vaccine brands for children may not be the most cost-effective choice. And doctors may be overlooking some cost factors when choosing vaccines, driving the market toward what is actually a more expensive option, according to a new study by University of Illinois researchers. [More]
New analysis finds less research attention is given to diseases of developing world

New analysis finds less research attention is given to diseases of developing world

Death is not distributed equally around the world. In high-income countries, people typically die in old age of chronic diseases such as cancer or cardiovascular problems. In low-income countries, death comes primarily from infectious and perinatal diseases, and strikes at a young age. [More]
FDA expands age indication of Adacel vaccine for immunization against tetanus, diphtheria, pertussis

FDA expands age indication of Adacel vaccine for immunization against tetanus, diphtheria, pertussis

Sanofi Pasteur, the vaccines division of Sanofi, announced today that the U.S. Food and Drug Administration (FDA) has expanded the approved age indication of Adacel® (Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed; Tdap) for active booster immunization for the prevention of tetanus, diphtheria, and pertussis as a single dose in persons 10 through 64 years of age. [More]
New instrument can conduct biological scans in fraction of time and cost of industry standard

New instrument can conduct biological scans in fraction of time and cost of industry standard

Northeastern University professor of pharmaceutical sciences, Tania Konry, has developed a single instrument that can conduct a wide range of biological scans in a fraction of the time and cost of industry standard equipment. That's because it uses considerably less material and ultra-sensitive detection methods to do the same thing. [More]
ADMA Biologics reports consolidated net loss of $15.5M in 2013

ADMA Biologics reports consolidated net loss of $15.5M in 2013

ADMA Biologics, Inc., a late-stage biopharmaceutical company that develops, manufactures, and intends to market specialty plasma-based biologics for the treatment and prevention of certain infectious diseases, today announced its financial results for the year ended December 31, 2013 and provided recent company developments as well as anticipated milestones for 2014. [More]
Researchers find 69% rise in pertussis vaccination rate among new mothers

Researchers find 69% rise in pertussis vaccination rate among new mothers

Changing the hospital orders for women who have just delivered a child led to a 69% increase in the new mothers' pertussis vaccination rate, providing protection for themselves and their newborns against the disease, commonly known as whooping cough, according to a study in the March issue of the American Journal of Obstetrics & Gynecology. [More]
Research roundup: Examining readmissions; easing doctor burnout

Research roundup: Examining readmissions; easing doctor burnout

Despite massive early IT problems, exchange enrollment is accelerating rapidly. While enrollment may not reach 7 million by the end of March, we expect at least 5 million to have enrolled by the close of the initial open-enrollment period. If enrollment falls far short, HHS could extend open enrollment for a fixed period to reach its 7 million target. ... We project that 5 million new beneficiaries will be covered by Medicaid and the Children's Health Insurance Program by the end of 2014. Medicaid managed-care enrollment of non-dual beneficiaries will increase by 20 percent from 2013 to 2014 and by 38 percent from 2013 to 2016. We expect that 75 percent of non-dual Medicaid beneficiaries will be covered by Managed Care Organizations starting in 2015, up from 63 percent in 2012 (Feb. 2014). [More]
MassBiologics gets FDA orphan drug designation for MBL-HCV1 antibody

MassBiologics gets FDA orphan drug designation for MBL-HCV1 antibody

MassBiologics of the University of Massachusetts Medical School has received an orphan drug designation from the U.S. Food and Drug Administration for MBL-HCV1, a monoclonal antibody developed to prevent hepatitis C virus recurrence in patients receiving a liver transplant. [More]
Abortion of female fetuses in northern India results in gender imbalance

Abortion of female fetuses in northern India results in gender imbalance

Modern ultrasound technology and economic pressure leads to female fetuses in the Ballabgarh area of northern India being aborted more often than male fetuses. Additionally, girls up to the age of five die more frequently than boys, which results in a gender imbalance in the area, according to Anand Krishnan, MD and doctoral candidate at Ume- University, who defends his thesis on 11 October. [More]
Healthcare providers report unaccompanied teens may not receive required vaccines

Healthcare providers report unaccompanied teens may not receive required vaccines

Healthcare providers report that older teens often go to the doctor without a parent or guardian, a new survey in the Journal of Adolescent Health reveals—and those teens may not get necessary vaccinations because there's no parent or guardian present to give consent. [More]
New report shows 6.6 million children under 5 died in 2012

New report shows 6.6 million children under 5 died in 2012

In 2012, approximately 6.6 million children worldwide - 18 000 children per day - died before reaching their fifth birthday, according to a new report released today by UNICEF, WHO, the World Bank Group and the United Nations Department of Economic and Social Affairs/Population Division. This is roughly half the number of under-fives who died in 1990, when more than 12 million children died. [More]
Undervaccination results in increased risk for whooping cough in young children

Undervaccination results in increased risk for whooping cough in young children

Undervaccination – not receiving all recommended vaccinations or not being vaccinated according to the Advisory Committee on Immunization Practices schedule – results in an increased risk for whooping cough in children 3 to 36 months of age, according to a new Kaiser Permanente study. [More]