New diabetes algorithm released by AACE for the management of type 2 diabetes

22. October 2009 00:19

A new, first-of-its-kind diabetes algorithm created to help achieve glycemic (blood sugar) control in type 2 patients was published online today in the September/October edition of Endocrine Practice. [More]

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Posted in: Medical Condition News

Tags: Cholesterol, Diabetes, Diabetes Mellitus, Education, Endocrinology, Growth Hormone, Hypoglycemia, Insulin, Obesity, Osteoporosis, Thiazolidinediones, Type 2 Diabetes

FDA approves Daiichi Sankyo's sNDA for Welchol

7. October 2009 09:04

Daiichi Sankyo, Inc. (DSI) announced today that the U.S. Food and Drug Administration (FDA) has approved the supplemental new drug application (sNDA) for Welchol® (colesevelam HCl) to be used as an adjunct to diet and exercise for the reduction of elevated low-density lipoprotein cholesterol (LDL-C) in boys and postmenarchal girls, 10 to 17 years of age, with heterozygous familial hypercholesterolemia (heFH) alone or in combination with a statin after failing an adequate trial of diet therapy. [More]

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Posted in: Pharmaceutical News

Tags: Atherosclerosis, Bone, Cancer, Cardiovascular Disease, CDC, Cholesterol, Constipation, Diabetes, Diabetes Mellitus, Diabetic Ketoacidosis, Diet, Dyslipidemia, Exercise, Gastroparesis, Headache, Hypercholesterolemia, Hyperlipidemia, Hypertriglyceridemia, Hypoglycemia, Insulin, Lipoprotein, Nausea, New Drug Application, Pancreatitis, Pregnancy, Rhinitis, Statin, Thiazolidinediones, Triglyceride, Type 1 Diabetes, Type 2 Diabetes, Vitamin K, Vomiting, Warfarin

Safety profiles of JANUVIA and JANUMET drugs established through clinical development program

28. September 2009 06:28

Merck has thoroughly reviewed the safety data for sitagliptin, and sitagliptin was not associated with an increase in the incidence of pancreatitis in preclinical studies or in clinical trials of up to two years in duration with more than 6,000 patients. [More]

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Posted in: Pharmaceutical News

Tags: Abdominal Pain, Amiloride, Anemia, Angioedema, Blindness, Breast Milk, Calcium, Cell, Chloramphenicol, Chromosome, Congestive Heart Failure, Creatinine, Cyclosporine, Dehydration, Diabetes, Diabetes Mellitus, Diabetic Ketoacidosis, Dialysis, Diarrhea, Diet, DNA, Estradiol, Ethanol, Exercise, Fertility, Furosemide, Glibenclamide, Headache, Heart Failure, Hospital, Hyperglycemia, Hyperinsulinemia, Hypersensitivity, Hypoglycemia, Hypothermia, Ibuprofen, Indigestion, Insulin, Isoniazid, Kidney Disease, Lymphoma, Metabolism, Metformin, Morphine, Nausea, Nursing, Obesity, Pancreatitis, Pharmacology, Pioglitazone, Pregnancy, Quinine, Salicylates, Sepsis, Septicemia, Sore Throat, Stress, Stroke, Sulfonylurea, Thiazolidinediones, Toxicology, Trauma, Type 1 Diabetes, Type 2 Diabetes, Urticaria, Vasculitis, Vomiting, Warfarin

European CHMP recommends Merck's JANUVIA and JANUMET as add-on to insulin

26. September 2009 01:23

Merck & Co., Inc., which operates in many countries as Merck Sharp & Dohme (MSD), has received a positive opinion from the European Medicines Agency’s (EMEA) Committee for Medicinal Products for Human Use (CHMP) for JANUVIA® tablets and JANUMET® tablets recommending their use as add-on to insulin for the treatment of type 2 diabetes. [More]

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Posted in: Medical Condition News | Pharmaceutical News

Tags: Abdominal Pain, Amiloride, Anemia, Angioedema, Blindness, Breast Milk, Calcium, Cell, Chloramphenicol, Chromosome, Congestive Heart Failure, Creatinine, Cyclosporine, Dehydration, Diabetes, Diabetes Mellitus, Diabetic Ketoacidosis, Dialysis, Diarrhea, Diet, DNA, Estradiol, Ethanol, Exercise, Fertility, Furosemide, Glibenclamide, Headache, Heart Failure, Hospital, Hyperglycemia, Hyperinsulinemia, Hypersensitivity, Hypoglycemia, Hypothermia, Ibuprofen, Indigestion, Insulin, Insulin Resistance, Isoniazid, Kidney Disease, Lymphoma, Metabolism, Metformin, Morphine, Nausea, New Drug Application, Nursing, Obesity, Pancreatitis, Pharmacology, Pioglitazone, Pregnancy, Quinine, Salicylates, Sepsis, Septicemia, Sore Throat, Stress, Stroke, Sulfonylurea, Thiazolidinediones, Toxicology, Trauma, Type 1 Diabetes, Type 2 Diabetes, Urticaria, Vasculitis, Vomiting, Warfarin

Adverse cardiovascular events during treatment with pioglitazone and rosiglitazone: Population-based cohort study

20. August 2009 18:54

Rosiglitazone, a drug used to treat type 2 diabetes, is associated with an increased risk of heart failure and death among older patients compared to a similar drug (pioglitazone), concludes a study published on bmj.com today. [More]

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Posted in: Medical Research News | Pharmaceutical News

Tags: Diabetes, Heart Failure, Hospital, Pioglitazone, Thiazolidinediones, Type 2 Diabetes

NDA for Exenatide once weekly accepted for FDA review

7. July 2009 21:55

Amylin Pharmaceuticals, Inc., Eli Lilly and Company and Alkermes, Inc. today announced that the New Drug Application (NDA) for exenatide once weekly has been accepted for review by the U.S. Food and Drug Administration (FDA). [More]

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Posted in: Pharmaceutical News

Tags: Diabetes, Exenatide, Hypoglycemia, Metformin, New Drug Application (NDA), Sulfonylurea, Thiazolidinediones, Type 2 Diabetes

Discovery of genetic markers to help fight diabetes

17. June 2009 00:07

Translational Genomics Research Institute (TGen) scientists have identified five genetic biomarkers that could help lead to improved treatments, with fewer side-effects, for patients with diabetes. [More]

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Posted in: Medical Research News

Tags: Actos, Biomarker, Diabetes, Diabetes Mellitus, Genetics, Pharmacogenetics, Potassium, Thiazolidinediones, Type 2 Diabetes

Diabetes drug pioglitazone shows potential against multiple sclerosis

26. May 2009 16:46

A drug currently FDA-approved for use in diabetes shows some protective effects in the brains of patients with relapsing remitting multiple sclerosis, researchers at the University of Illinois at Chicago College of Medicine report in a study currently available online in the Journal of Neuroimmunology. [More]

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Posted in: Drug Trial News

Tags: Actos, Cytokines, Immunology, Multiple Sclerosis, Neuron, Pioglitazone, Thiazolidinediones, Type 2 Diabetes

People with Ala12 gene variant need to watch out for high fat in their diets

6. January 2009 21:56

New evidence in mice bolsters the notion that a version of a gene earlier shown to protect lean people against weight gain and insulin resistance can have the opposite effect in those who eat a high-fat diet and are heavier, reveals a report in the January 7th issue of the journal Cell Metabolism, a Cell Press publication. [More]

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Posted in: Medical Research News

Tags: Cell Metabolism, Diabetes, Diet, Gene Expression, Genetics, Insulin, Insulin Resistance, Metabolic Syndrome, Metabolism, Thiazolidinediones, Type 2 Diabetes

Thiazolidinediones doubles risk of fractures in women

10. December 2008 16:34

New findings out of Wake Forest University School of Medicine and the University of East Anglia show that long-term use of a popular class of oral diabetic drugs doubles the risk of fractures in women with type 2 diabetes. [More]

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Posted in: Women's Health News

Tags: Bone, Bone Marrow, Bone Mineral Density, Congestive Heart Failure, Diabetes, Heart Failure, Pioglitazone, Seniors, Spine, Thiazolidinediones, Type 2 Diabetes

New evidence shows that the heart beats to its own drummer

3. December 2008 07:55

They've uncovered some of the molecular circuitry within the cardiovascular system itself that controls the daily rise and fall of blood pressure and heart rate. The findings might also explain why commonly used diabetes drugs come with cardiovascular benefits, according to the researchers. [More]

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Posted in: Medical Research News

Tags: Blood Pressure, Brain, Cell Metabolism, Circadian Rhythm, Diabetes, Genetics, Heart Attack (Myocardial Infarction), Metabolism, Nervous System, Physiology, Pioglitazone, Stroke, Thiazolidinediones, Veterans Affairs

Risks associated with diabetes drug rosiglitazone may be higher than those with pioglitazone

24. November 2008 21:42

Older adults who take the diabetes medication rosiglitazone appear to have a higher risk of death and heart failure than those taking the related medication pioglitazone, according to a report in the November 24 issue of Archives of Internal Medicine. [More]

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Posted in: Drug Trial News

Tags: Congestive Heart Failure, Diabetes, Heart Attack (Myocardial Infarction), Heart Failure, Insulin, Insulin Resistance, Pioglitazone, Seniors, Stroke, Thiazolidinediones

FDA continues review of Takeda's NDA for Alogliptin

12. October 2008 18:27

Takeda Pharmaceutical Company Limited has announced that Takeda Global Research and Development Center, Inc., a wholly owned United States (U.S.) subsidiary, received notification that the U.S. Food and Drug Administration (FDA) will not be able to complete its review of the alogliptin New Drug Application (NDA) by the Prescription Drug User Fee Act (PDUFA) date of October 27, 2008. [More]

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Posted in: Pharmaceutical News

Tags: Diabetes, Diet, Exercise, Hypoglycemia, Insulin, Metformin, New Drug Application (NDA), Prescription Drug, Sulfonylurea, Thiazolidinediones, Type 2 Diabetes

Advances in the management of diabetes mellitus

1. September 2008 18:54

The need for long term studies to establish the best means of treating Diabetes, was underlined by Prof John Cleland from the University of Hull at the ESC Congress in Munich. Prof Cleland listed the latest treatment available for patients and voiced his concern about the side-effects and efficacy of available anti-diabetic drugs. [More]

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Posted in: Medical Condition News

Tags: Blood Pressure, Carbohydrate, Cardiovascular Disease, Diabetes, Diabetes Mellitus, Exenatide, Hypertension (High Blood Pressure), Insulin, Lipids, Metformin, Neuropathy, Obesity, Physiology, Pioglitazone, Pulmonary Oedema, Seniors, Stroke, Thiazolidinediones, Type 1 Diabetes, Weight Loss

Thiazolidinediones - diabetes drugs carry significant cardiovascular risks

28. August 2008 17:58

A class of oral drugs used to treat type 2 diabetes may significantly increase the risk of serious cardiovascular events, according to an editorial published online in Heart Wednesday by two Wake Forest University School of Medicine faculty members. [More]

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Posted in: Pharmaceutical News

Tags: Blood Pressure, Cardiovascular Disease, Cholesterol, Congestive Heart Failure, Diabetes, Heart Failure, Pioglitazone, Seniors, Thiazolidinediones, Triglyceride, Type 2 Diabetes, Veterans Affairs

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Thiazolidinediones News and Research

New diabetes algorithm released by AACE for the management of type 2 diabetes

FDA approves Daiichi Sankyo's sNDA for Welchol

Safety profiles of JANUVIA and JANUMET drugs established through clinical development program

European CHMP recommends Merck's JANUVIA and JANUMET as add-on to insulin

Adverse cardiovascular events during treatment with pioglitazone and rosiglitazone: Population-based cohort study

NDA for Exenatide once weekly accepted for FDA review

Discovery of genetic markers to help fight diabetes

Diabetes drug pioglitazone shows potential against multiple sclerosis

People with Ala12 gene variant need to watch out for high fat in their diets

Thiazolidinediones doubles risk of fractures in women

New evidence shows that the heart beats to its own drummer

Risks associated with diabetes drug rosiglitazone may be higher than those with pioglitazone

FDA continues review of Takeda's NDA for Alogliptin

Advances in the management of diabetes mellitus

Thiazolidinediones - diabetes drugs carry significant cardiovascular risks

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