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Thrombosis is the formation or presence of a thrombus (blood clot) inside a blood vessel.
FDA recommens approval of Daiichi Sankyo's once-daily SAVAYSA for patients with NVAF

FDA recommens approval of Daiichi Sankyo's once-daily SAVAYSA for patients with NVAF

Daiichi Sankyo Company, Limited (hereafter, Daiichi Sankyo) today announced that the U.S. Food and Drug Administration's Cardiovascular and Renal Drugs Advisory Committee voted 9 to 1 to recommend approval of once-daily SAVAYSA (edoxaban) 60 mg dosing regimen for the reduction in risk of stroke and systemic embolic events (SEE) in patients with non-valvular atrial fibrillation (NVAF). [More]
Penn Medicine-developed drug gets FDA orphan status for PNH treatment

Penn Medicine-developed drug gets FDA orphan status for PNH treatment

A Penn Medicine-developed drug has received orphan status from the Food and Drug Administration (FDA) this month for the treatment of paroxysmal nocturnal hemoglobinuria (PNH), a rare, life-threatening disease that causes anemia due to destruction of red blood cells and thrombosis. [More]
Newly developed agent filters out toxins from body in the event of overdose

Newly developed agent filters out toxins from body in the event of overdose

Every minute counts in the event of an overdose. ETH professor Jean-Christophe Leroux and his team have developed an agent to filter out toxins from the body more quickly and efficiently. [More]
New study on global burden of venous thromboembolism

New study on global burden of venous thromboembolism

A study on the global burden of venous thromboembolism—when a dangerous clot forms in a blood vessel—found that annual incidences range from 0.75 to 2.69 per 1,000 individuals in the population. [More]
New implantable device can control heart failure

New implantable device can control heart failure

A new, implantable device to control heart failure is showing promising results in the first trial to determine safety and effectiveness in patients, according to lead researcher Dr. William Abraham of The Ohio State University Wexner Medical Center. [More]
Research performed in anemic mice shows acetate stimulates the formation of red blood cells

Research performed in anemic mice shows acetate stimulates the formation of red blood cells

UT Southwestern Medical Center researchers seeking novel treatments for anemia found that giving acetate, the major component of household vinegar, to anemic mice stimulated the formation of new red blood cells. [More]
Study: Dietary polyunsaturated fatty acids may reduce coronary heart disease risk

Study: Dietary polyunsaturated fatty acids may reduce coronary heart disease risk

A recent study completed at the University of Eastern Finland shows that dietary polyunsaturated fatty acids may reduce the risk of coronary heart disease. The sources of polyunsaturated fatty acids include fish, vegetable oils, and nuts. [More]
CorMedix submits IND application to FDA for Neutrolin

CorMedix submits IND application to FDA for Neutrolin

CorMedix Inc., a pharmaceutical company focused on developing and commercializing therapeutic products for the prevention and treatment of cardiac, renal and infectious disease, is pleased to announce that an Investigational New Drug application (IND) for Neutrolin was submitted to the United States Food and Drug Administration on Wednesday, September 24, 2014. [More]
Elsevier honored at BMA Medical Book Awards ceremony

Elsevier honored at BMA Medical Book Awards ceremony

Elsevier, a world-leading provider of scientific, technical and medical information products and services, announced today that 28 of its professional and scholarly products were honored at the British Medical Association's annual BMA Medical Book Awards ceremony at BMA House in London on Sept. 22, 2014. [More]
Studies explore role of STXBP5 gene in development of cardiovascular disease

Studies explore role of STXBP5 gene in development of cardiovascular disease

Two independent groups of researchers led by Sidney (Wally) Whiteheart, PhD, of the University of Kentucky, and Charles Lowenstein, MD, of the University of Rochester, have published important studies exploring the role that a gene called STXBP5 plays in the development of cardiovascular disease. [More]
New guidance can help physicians determine best oral blood thinners for patients

New guidance can help physicians determine best oral blood thinners for patients

Physicians around the world now have guidance that can help them determine the best oral blood thinners to use for their patients suffering from blood clots in their veins, thanks to a patient of The Ottawa Hospital who asked his physician a question he couldn't answer. [More]
New guideline recommends against routine use of bed rest in pregnancy

New guideline recommends against routine use of bed rest in pregnancy

In a new guideline, the Society for Maternal-Fetal Medicine has recommended against the routine use of bed rest in pregnancy. [More]
Ambulance administration of antiplatelet medication may help heart attack patients

Ambulance administration of antiplatelet medication may help heart attack patients

Ambulance administration of the antiplatelet medication ticagrelor to patients with a type of heart attack known as ST segment elevation myocardial infarction (STEMI) is not better than hospital administration, in terms of improving blood flow in blocked arteries before a revascularisation procedure, according to a new study presented at ESC Congress 2014 today. [More]
New data confirms that mechanical heart valves raise risks during and after pregnancy

New data confirms that mechanical heart valves raise risks during and after pregnancy

The fact that mechanical heart valves increase risks during and after pregnancy, has been confirmed by data from the ROPAC registry presented for the first time today in an ESC Congress Hot Line session by Professor Jolien W. Roos-Hesselink, co-chair with Professor Roger Hall of the registry's executive committee. [More]
ESC launches first recommendations on use of all new oral anticoagulants in pulmonary embolism

ESC launches first recommendations on use of all new oral anticoagulants in pulmonary embolism

The first recommendations on the use of all new oral anticoagulants in pulmonary embolism are published today in new ESC Guidelines. [More]
Janssen, Bayer announce expansion of EXPLORER global cardiovascular research program for XARELTO

Janssen, Bayer announce expansion of EXPLORER global cardiovascular research program for XARELTO

Janssen Research & Development, LLC and its development partner, Bayer HealthCare, announced today the expansion of the EXPLORER global cardiovascular research program for XARELTO (rivaroxaban) to include additional high-risk patient populations. [More]
Penn receives orphan status in Europe for treatment of PNH

Penn receives orphan status in Europe for treatment of PNH

A Penn Medicine-developed drug has received orphan status in Europe this week for the treatment of paroxysmal nocturnal hemoglobinuria (PNH), a rare, life-threatening disease that causes anemia due to destruction of red blood cells and thrombosis. [More]
ProMedica participates in innovative research into development of non-invasive treatment for BPH

ProMedica participates in innovative research into development of non-invasive treatment for BPH

ProMedica is participating in innovative research into the development of a safe, non-invasive treatment for BPH or enlarged prostate. BPH can block the flow of urine out of the bladder and cause bladder, urinary tract or kidney problems. [More]
Study explores the effectiveness of stents in treating vein obstructions

Study explores the effectiveness of stents in treating vein obstructions

Jobst Vascular Institute is conducting pioneering research that looks at using stents to treat blocked veins. For years, stents - small mesh tubes - have been used to treat narrowed or blocked arteries; however none are specifically designed for use in veins. [More]
Researchers compare benefits of bivalirudin and heparin for patients undergoing coronary stenting

Researchers compare benefits of bivalirudin and heparin for patients undergoing coronary stenting

Bivalirudin and heparin are two anticoagulant options for patients undergoing coronary stenting for ischemic heart disease. Bivalirudin, a newer anticoagulant, has been touted as being as effective as generic heparin, but with nearly half the rate of bleeding. [More]