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Thrombosis is the formation or presence of a thrombus (blood clot) inside a blood vessel.
Study reveals that prolonged Dkk1 signaling can lead to fibrosis, stiffening of artery walls

Study reveals that prolonged Dkk1 signaling can lead to fibrosis, stiffening of artery walls

The hardening of arteries is a hallmark of atherosclerosis, an often deadly disease in which plaques, excessive connective tissue, and other changes build up inside vessel walls and squeeze off the flow of oxygen-rich blood throughout the body. [More]
Breathing motor vehicle emissions triggers change in HDL cholesterol

Breathing motor vehicle emissions triggers change in HDL cholesterol

Academic researchers have found that breathing motor vehicle emissions triggers a change in high-density lipoprotein cholesterol, altering its cardiovascular protective qualities so that it actually contributes to clogged arteries. [More]
Study shows patient satisfaction from a pharmacy program

Study shows patient satisfaction from a pharmacy program

As hospitals look for ways to improve patient satisfaction and boost their Medicare reimbursement, a Henry Ford Hospital study found that an inpatient pharmacist-directed anticoagulation service might be an unexpected opportunity. [More]
Gene offers new insights into treatment strategies for deep-vein thrombosis

Gene offers new insights into treatment strategies for deep-vein thrombosis

A gene associated with both protection against bacterial infection and excessive blood clotting could offer new insights into treatment strategies for deep-vein thrombosis -- the formation of a harmful clot in a deep vein. [More]

ECMO can be used on neonates with severe respiratory failure until lung transplantation, say scientists

Adults with end-stage respiratory failure and pulmonary hypertension requiring ECMO (extracorporeal membrane oxygenation) have been "bridged" toward lung transplantation with novel lung assist devices such as the Novalung. [More]

Gray matter atrophy underlies PD subtypes

Patients with the postural instability gait difficulty subtype of Parkinson’s disease have marked gray matter atrophy relative to those with the tremor dominant subtype, shows research. [More]

GOLD predicts mortality in COPD

The Global Initiative for Chronic Obstructive Lung Disease classification of chronic obstructive pulmonary disease predicts mortality better than the 2011 ABCD scoring system, report Norwegian researchers. [More]
COPD-asthma overlap ‘needs greater recognition’

COPD-asthma overlap ‘needs greater recognition’

More attention should be given to patients who have chronic obstructive pulmonary disease and concomitant asthma, after a study showed that nearly one-fifth of patients with COPD fall into this subtype. [More]
Exclusion diet boosts anal fissure healing

Exclusion diet boosts anal fissure healing

Research published in the American Journal of Gastroenterology shows that an exclusion diet combined with medical treatment can increase healing rates in patients with chronic anal fissure who have been referred for surgery. [More]

New guidance on radioiodine therapy use after radiographic studies

Researchers have provided new evidence that could act as a guide for the use of radioiodine therapy after patients have undergone radiographic imaging studies that use iodine as a contrasting agent. [More]
Measles outbreak prompts national vaccination catch-up program in UK

Measles outbreak prompts national vaccination catch-up program in UK

Health officials in the UK have announced a national catch-up program to target 10–16 year olds who did not receive the combined measles, mumps, and rubella vaccination in early childhood due to fears about links with autism. [More]
Specific inflammatory pattern found in patients with pneumonia and COPD

Specific inflammatory pattern found in patients with pneumonia and COPD

Patients with community-acquired pneumonia on a background of chronic obstructive pulmonary disease have a different early inflammatory pattern than patients with CAP only, a prospective study shows. [More]

FDA approves Octapharma USA's BLA for octaplex

The U.S. Food and Drug Administration has accepted Octapharma USA's Biological License Application for octaplex. [More]
Revised criteria improve early-onset dementia diagnosis

Revised criteria improve early-onset dementia diagnosis

Updated diagnostic criteria based on the Frontotemporal Dementia Consensus are “encouragingly” sensitive and specific in identifying patients who have early-onset dementia, a study finds. [More]
Autism linked to epilepsy drug use in pregnancy

Autism linked to epilepsy drug use in pregnancy

Children born to mothers who take valproate during pregnancy are at increased risk for developing autism compared with children of women who did not take the epilepsy drug, Danish research shows. [More]

Laparoscopic radical nephropathy effective for advanced renal masses

Laparoscopic radical nephrectomy is an effective treatment approach for individuals with renal cell carcinoma who have larger or more advanced renal masses, report researchers. [More]

Continuous monitoring flags acute compartment syndrome

Continuous intracompartmental pressure monitoring is highly accurate for the detection of acute compartment syndrome after tibial diaphyseal fracture, say UK researchers who believe it may allow diagnosis before signs and symptoms occur. [More]
IL-1 antagonist relieves dry eyes

IL-1 antagonist relieves dry eyes

Clinical trial results point to a role for interleukin-1 targeted agents for the treatment of dry eye disease associated with meibomian gland dysfunction. [More]
Biventricular pacing best in atrioventricular block patients

Biventricular pacing best in atrioventricular block patients

Use of biventricular rather than conventional right ventricular pacing results in better clinical outcomes in patients who have heart failure with atrioventricular block and left ventricular systolic dysfunction, show the results of BLOCK HF. [More]

Geriatric focus cuts hospital costs

An Acute Care for Elders unit with a focus on identifying and treating geriatric syndromes significantly reduces costs and 30-day readmissions for elderly patients, a study finds. [More]