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Thrombosis is the formation or presence of a thrombus (blood clot) inside a blood vessel.
Betrixaban scores near miss for extended thromboprophylaxis

Betrixaban scores near miss for extended thromboprophylaxis

Extended thromboprophylaxis with the direct factor Xa inhibitor betrixaban just fails to show superiority to standard treatment with enoxaparin in acutely ill medical patients. [More]
SIPPET study may have implications for treatment of patients with severe hemophilia A

SIPPET study may have implications for treatment of patients with severe hemophilia A

SIPPET, a study which involved 42 centers in 14 countries in Europe, North and South America, Africa and Asia was designed to definitively settle the long-debated question whether factor VIII concentrates from different sources (plasma-derived containing VWF or recombinant technology) differ in risk of inhibitor development in previously untreated children (PUPs) with severe hemophilia A. [More]
Bare metal stents no longer advisable for high bleeding risk ACS patients

Bare metal stents no longer advisable for high bleeding risk ACS patients

A polymer-free, drug-coated stent gives markedly better outcomes than a bare metal stent in patients with acute coronary syndromes and risk factors for bleeding, report researchers. [More]
Pre-procedural use of antiplatelet therapy becoming less routine in heart attack treatment

Pre-procedural use of antiplatelet therapy becoming less routine in heart attack treatment

Doctors worried about dangerous blood clots in patients undergoing a coronary artery procedure— such as angioplasty to treat a heart attack — will often administer antiplatelet therapy to head off complications. [More]
PCI with polymer-free BA9 drug-coated stent better than bare metal stent in ACS patients

PCI with polymer-free BA9 drug-coated stent better than bare metal stent in ACS patients

Patients with acute coronary syndromes (ACS) who are at high risk for bleeding have significantly lower rates of target lesion revascularisation and fewer adverse events after undergoing percutaneous coronary intervention (PCI) with a polymer-free biolimus-A (BA9) drug-coated stent than with those receiving a bare metal stent (BMS) in results from a sub-study of the LEADERS FREE trial reported for the first time in a late-breaker session at EuroPCR 2016. [More]
Minihepcidins may potentially treat serious genetic blood diseases in children, adults

Minihepcidins may potentially treat serious genetic blood diseases in children, adults

New research suggests that synthetic peptides called minihepcidins may potentially treat two serious genetic blood diseases in children and adults. Although those diseases, beta-thalassemia and polycythemia vera, have opposite effects on red blood cell production, treating animals with minihepcidin helps to restore normal levels of red blood cells and reduces spleen enlargement. It also controls the accumulation of excess levels of iron in beta-thalassemia that often causes severe toxic effects. [More]
Reasons for life-threatening blood clots in elite athletes

Reasons for life-threatening blood clots in elite athletes

Mary Cushman, M.D., M.Sc., a professor of medicine and director of the Thrombosis and Hemostasis Program at the University of Vermont, provides commentary on the causes of life-threatening blood clots in elite athletes. [More]
Increased fitness can normalize platelet function quickly

Increased fitness can normalize platelet function quickly

Women with poor physical fitness display significantly higher platelet activation than women with average to very good fitness. That is the major finding of a study of 62 young women, conducted by the research groups of Ivo Volf and Rochus Pokan and sponsored by the Austrian Heart Foundation. Platelet (thrombocyte) activation can lead to the formation of potentially life-threatening blood clots. [More]
Study explores benefits of hand and shoulder surgeries performed at outpatient centers

Study explores benefits of hand and shoulder surgeries performed at outpatient centers

A large study of hand and shoulder surgeries performed at a freestanding, outpatient center found few complications--0.2 percent in nearly 29,000 patients over an 11-year period. The study appears in the new issue of the Journal of Bone and Joint Surgery. [More]
Interdisciplinary researchers to explore ethical issues of pregnant women during Zika crisis

Interdisciplinary researchers to explore ethical issues of pregnant women during Zika crisis

The emerging Zika virus epidemic is bringing to light a longstanding ethical challenge in medical research: the inclusion of pregnant women. With new funding from the Wellcome Trust, an interdisciplinary team of scholars will focus on issues of ethics and research in pregnancy and women of reproductive age, beginning with the current Zika context and later expanding to general public health research. [More]
Aspirin resistance signals increased stroke severity

Aspirin resistance signals increased stroke severity

Stroke severity and infarct volume are significantly increased among patients who become resistant to aspirin, show study findings published in Neurology. [More]
Ariste Medical develops drug-eluting mesh for more effective open hernia repair

Ariste Medical develops drug-eluting mesh for more effective open hernia repair

Ariste Medical has revealed new research outlining the company’s novel method for addressing medical device failure in open ventral hernia repair. [More]
Magnetically controlled enzyme solutions can be used for targeted treatment of cancer, thrombosis

Magnetically controlled enzyme solutions can be used for targeted treatment of cancer, thrombosis

Researchers from ITMO University, the Hebrew University of Jerusalem and Cyril and Methodius University in Skopje have fabricated a new magnetically controlled material composed of enzymes entrapped directly within magnetite particles. [More]
Micra Transcatheter Pacing System approved to treat heart rhythm disorders

Micra Transcatheter Pacing System approved to treat heart rhythm disorders

The U.S. Food and Drug Administration today approved the first pacemaker that does not require the use of wired leads to provide an electrical connection between the pulse-generating device and the heart. While the Micra Transcatheter Pacing System works like other pacemakers to regulate heart rate, the self-contained, inch-long device is implanted directly in the right ventricle chamber of the heart. [More]
European Medicines Agency approves first-ever treatment for hereditary factor X deficiency

European Medicines Agency approves first-ever treatment for hereditary factor X deficiency

Bio Products Laboratory, Limited (BPL) today announced that the European Medicines Agency has granted marketing authorisation for Coagadex. [More]
New tool may help clinicians provide more personalized treatment strategies following coronary stent procedures

New tool may help clinicians provide more personalized treatment strategies following coronary stent procedures

Nearly 1 million people in the United States receive coronary artery stents each year. Nearly all stent patients are expected to take dual antiplatelet therapy (DAPT) using the combination of aspirin and a second antiplatelet medication to prevent the formation of blood clots. Exactly how long patients should receive DAPT has been debatable. [More]
UC San Diego Health participates in nationwide clinical study on hemophilia B gene therapy

UC San Diego Health participates in nationwide clinical study on hemophilia B gene therapy

The Hemophilia and Thrombosis Treatment Center at UC San Diego Health has joined a nationwide clinical trial testing a potential gene therapy that may one day provide a better and long-lasting treatment for people with hemophilia B. [More]
Oral contraceptives increase rare stroke risk in obese women

Oral contraceptives increase rare stroke risk in obese women

Researchers have found that obese women taking oral contraceptives have an increased risk of cerebral venous thrombosis and should be educated about this risk accordingly. [More]
Study shows gut microbes alter platelet function, heightens risk of heart attack and stroke

Study shows gut microbes alter platelet function, heightens risk of heart attack and stroke

In a combination of both clinical studies of over 4,000 patients and animal model studies, Cleveland Clinic researchers have demonstrated -- for the first time -- that gut microbes alter platelet function and risk of blood clot-related illnesses like heart attack and stroke. [More]
New study sheds light on challenges in addressing post-operative bleeding in newborns

New study sheds light on challenges in addressing post-operative bleeding in newborns

A new study finds significant differences between the blood clot structure in adults and newborns, helping researchers better understand the challenges in addressing post-operative bleeding in neonatal patients. [More]
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