Thymine News and Research

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Thymine is one of the four bases in DNA that make up the letters ATGC, thymine is the "T". The others are adenine, guanine, and cytosine. Thymine always pairs with adenine.

Research finds higher rate of rare tandem repeats in the genomes of individuals with schizophrenia

In our cells, the language of DNA is written, making each of us unique. A tandem repeat occurs in DNA when a pattern of one or more nucleotides – the basic structural unit of DNA coded in the base of chemicals cytosine (C), adenine (A), guanine (G) and thymine (T) – is repeated multiple times in tandem. An example might be: CAG CAG CAG, in which the pattern CAG is repeated three times.

30 Nov 2022

Study shows clear shifts in SARS-CoV-2 mutational spectrum during evolution

Researchers examined whether the mutational process of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) itself has changed during the evolution of SARS-CoV-2.

23 Nov 2022

Virology of the human monkeypox virus

A new review to be posted in the Virus Research journal aims to provide an overview of the recent advances reported concerning hMPXV virology.

21 Sep 2022

Common molecular tool for DNA labelling shows unexpected anticancer properties

Scientists at the UNC School of Medicine have made the surprising discovery that a molecule called EdU, which is commonly used in laboratory experiments to label DNA, is in fact recognized by human cells as DNA damage, triggering a runaway process of DNA repair that is eventually fatal to affected cells, including cancer cells.

23 Aug 2022

GenomeBits representation of SARS-CoV-2 Delta and Omicron genome sequences

In a new study, researchers uncovered distinct genomic features of SARS-CoV-2 Delta and Omicron variants.

13 Jul 2022

SARS-CoV-2 variant-specific polymerase chain reaction assay for SARS-CoV-2 genomic surveillance

Researchers reported on the misclassification of the SARS-CoV-2 Omicron BA.1 subvariant as Omicron BA.2 subvariant in an automated variant-specific polymerase chain reaction analysis.

17 Jun 2022

Scientists provide crucial insights into the roles of inflammation and oxidative stress in certain cancers

Rampant inflammation has long been linked to cancer but exactly how it pushes healthy cells to transform into malignant ones has remained a mystery.

7 Jun 2022

Study identified multiple siRNAs spanning the SARS-CoV-2 genome with potent antiviral activity

A recent study demonstrated that RNA interference could prophylactically protect against SARS-CoV-2.

24 Mar 2022

Study investigates the spread of SARS-CoV-2 genetic diversity on a fishing boat

In a recent study posted to the bioRxiv* preprint server, a team of researchers from Washington, United States, investigated the transmission of viral genetic diversity during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) superspreading outbreak among the crew members on a fishing boat.

14 Feb 2022

Error rate of bacterial DNA polymerase is consistently higher under microgravity, study shows

On 22 May 2019, scientists from Queen's University boarded a modified Falcon 20 aircraft at Ottawa airport. Scheduled was a 'vomit comet' flight, where the plane repeatedly climbs to 8km in a steep parabola, alternating with a descent in freefall.

29 Nov 2021

Impact of ultraviolet disinfection on nosocomial transmission of SARS-CoV-2 and other infectious diseases

A new review article determines the role of UV disinfection for nosocomial transmission of COVID-19 and other infectious diseases.

22 Nov 2021

Inhibition of SARS-CoV-2 helicase by single DNA lesions

In a paper, the impact of specific DNA lesions is investigated regarding the unwinding activity of NSP13.

18 Oct 2021

Melanoma mutations result from a chemical conversion in DNA fueled by sunlight, study reports

The mutations that give rise to melanoma result from a chemical conversion in DNA fueled by sunlight -; not just a DNA copying error as previously believed, reports a study by Van Andel Institute scientists published today in Science Advances.

30 Jul 2021

How bacterial cells have been engineered to produce virus-resistant synthetic polymers

A recent Science paper discusses the utilization of a previously reported synthetic Escherichia coli to produce virus-resistant synthetic polymers.

3 Jun 2021

Could a mathematical application of information theory identify and predict SARS-CoV-2 mutations?

An interesting new study by researchers at the University of Portsmouth, UK, describes the use of a mathematical method to sequence genomes based on information theory. The method offers an alternative to clinical techniques, allowing mutations to be detected and possibly even predicted. In this way, it opens new research opportunities in bioinformatics and genetics.

31 May 2021

High-throughput system can regulate gene expression for treating sickle cell disease, beta thalassemia

St. Jude Children's Research Hospital scientists have developed an integrated, high-throughput system to better understand and possibly manipulate gene expression for treatment of disorders such as sickle cell disease and beta thalassemia. The research appears today in the journal Nature Genetics.

7 May 2021

Thymine News and Research

Further Reading

Research finds higher rate of rare tandem repeats in the genomes of individuals with schizophrenia

Study shows clear shifts in SARS-CoV-2 mutational spectrum during evolution

Virology of the human monkeypox virus

Common molecular tool for DNA labelling shows unexpected anticancer properties

GenomeBits representation of SARS-CoV-2 Delta and Omicron genome sequences

SARS-CoV-2 variant-specific polymerase chain reaction assay for SARS-CoV-2 genomic surveillance

Scientists provide crucial insights into the roles of inflammation and oxidative stress in certain cancers

Study identified multiple siRNAs spanning the SARS-CoV-2 genome with potent antiviral activity

Study investigates the spread of SARS-CoV-2 genetic diversity on a fishing boat

Error rate of bacterial DNA polymerase is consistently higher under microgravity, study shows

Impact of ultraviolet disinfection on nosocomial transmission of SARS-CoV-2 and other infectious diseases

Inhibition of SARS-CoV-2 helicase by single DNA lesions

Melanoma mutations result from a chemical conversion in DNA fueled by sunlight, study reports

How bacterial cells have been engineered to produce virus-resistant synthetic polymers

Could a mathematical application of information theory identify and predict SARS-CoV-2 mutations?

High-throughput system can regulate gene expression for treating sickle cell disease, beta thalassemia

Unique system detects small changes in DNA structures

Rice bioengineer wins NIH support for a new strategy to fight cystic fibrosis

Prime editing enables more precise correction of genetic problems than traditional CRISPR

NIST compiles the first detailed tutorial on DNA origami

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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