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Researchers discover protein for treatment of anaplastic thyroid carcinoma

Researchers discover protein for treatment of anaplastic thyroid carcinoma

Anaplastic thyroid carcinoma (ATC) is an aggressive type of cancer with a poor prognosis for which there is currently no effective treatment. Researchers from the National University of Singapore (NUS) have discovered for the first time that an epithelial basement membrane protein, called laminin-5 gamma-2 (LAMC2), has the potential to be an ideal target for the treatment of ATC. [More]
NUS researchers discover promising treatment for anaplastic thyroid carcinoma

NUS researchers discover promising treatment for anaplastic thyroid carcinoma

Anaplastic thyroid carcinoma is an aggressive type of cancer with a poor prognosis for which there is currently no effective treatment. Researchers from the National University of Singapore have discovered for the first time that an epithelial basement membrane protein, called laminin-5 gamma-2 (LAMC2), has the potential to be an ideal target for the treatment of ATC. [More]
New comprehensive textbook on tiny parathyroid glands for endocrine surgeons

New comprehensive textbook on tiny parathyroid glands for endocrine surgeons

How robots enable no-neck-scar thyroid surgery and advanced imaging helps surgeons track down often elusive, tiny parathyroid glands are timely topics for a new comprehensive textbook for endocrine surgeons. [More]
Scientists discover new mechanism governing brain stem cell proliferation

Scientists discover new mechanism governing brain stem cell proliferation

Higher mammals, such as humans, have markedly larger brains than other mammals. Scientists from the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden recently discovered a new mechanism governing brain stem cell proliferation. [More]
Pfizer and Merck join forces to explore therapeutic potential of anti-PD-1 therapy

Pfizer and Merck join forces to explore therapeutic potential of anti-PD-1 therapy

Pfizer Inc. announced today that it has agreed with Merck & Co., Inc., known as MSD outside the United States and Canada ("Merck"), through two Merck subsidiaries, to explore the therapeutic potential of Merck's investigational anti-PD-1 therapy, MK-3475, in combination with two Pfizer oncology assets. [More]
Scientists discover potential cure for triple negative breast cancer

Scientists discover potential cure for triple negative breast cancer

Scientists have discovered a potential cure for one of the most aggressive and least treatable forms of breast cancer called "triple negative breast cancer." In laboratory experiments involving human cancer cells, scientists used a virus similar to the one that helped eradicate smallpox to coax cancer cells to produce a protein which makes them susceptible to radioactive iodine. [More]
NeoGenomics validates and launches series of NeoTYPE cancer profiling tests

NeoGenomics validates and launches series of NeoTYPE cancer profiling tests

NeoGenomics, Inc., a leading provider of cancer-focused genetic and molecular testing services, announced today that it has validated and launched a series of NeoTYPE cancer profiling tests covering 22 different categories of cancer. Each of these tests is designed to investigate the most common and actionable genomic abnormalities reported for that particular tumor. [More]
New pre-clinical data shows potential protective effects of GFT505 in different types of cancer

New pre-clinical data shows potential protective effects of GFT505 in different types of cancer

GENFIT, a biopharmaceutical company at the forefront of drug discovery and development, focusing on the early diagnosis and preventive treatment of cardiometabolic and associated disorders, today announces new pre-clinical data demonstrating the inhibitory effects of GFT505 on the proliferation of cancer cells of different origins. [More]
Researchers reveal role of extra thymus gland in the network of body's natural defense systems

Researchers reveal role of extra thymus gland in the network of body's natural defense systems

The thymus gland is a critical component of the human immune system that is responsible for the development of T-lymphocytes, or T-cells, which help organize and lead the body's fighting forces against harmful organisms like bacteria and viruses. [More]
Research roundup: Nursing home transitions; the impact of raising Medicare premiums; workers' views of job-based insurance

Research roundup: Nursing home transitions; the impact of raising Medicare premiums; workers' views of job-based insurance

Each week, KHN compiles a selection of recently released health policy studies and briefs. [More]

BMH-21 chemical compound has ability to shut down a common cancer process

Johns Hopkins scientists say a previously known but little studied chemical compound targets and shuts down a common cancer process. In studies of laboratory-grown human tumor cell lines, the drug disrupted tumor cell division and prevented growth of advanced cancer cells. [More]
Minority patients and those of lower socioeconomic status are more likely to have advanced thyroid cancer

Minority patients and those of lower socioeconomic status are more likely to have advanced thyroid cancer

​UCLA researchers have found that minority patients and those of lower socioeconomic status are far more likely to have advanced thyroid cancer when they are diagnosed with the disease than white patients and those in higher economic brackets. [More]
Apitope-led consortium awarded FP7 Health Innovation funding to develop Graves' disease vaccine

Apitope-led consortium awarded FP7 Health Innovation funding to develop Graves' disease vaccine

Apitope, the drug discovery and development company focused on treating the underlying cause of autoimmune diseases, today announces that the consortium, led by Apitope, which includes GSK Vaccines, Quintiles and KWS Biotest Limited, has been awarded prestigious Framework Programme 7 Health Innovation funding by the European Commission to develop its Graves' disease therapeutic vaccine, including a Phase I first-in-man study in Graves' disease patients. [More]
Navidea Biopharmaceuticals, GMST sign distribution agreement for Lymphoseek Injection in Taiwan

Navidea Biopharmaceuticals, GMST sign distribution agreement for Lymphoseek Injection in Taiwan

Navidea Biopharmaceuticals, Inc., a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, announced today it has entered into a distribution agreement for Lymphoseek (technetium Tc 99m tilmanocept) Injection in Taiwan with Global Medical Solutions Taiwan, Ltd., a leading in-country distributor of nuclear medicine and diagnostic imaging products. [More]

Researchers develop new tool that accurately predicts individual's risk of colorectal cancer

​Researchers at Cleveland Clinic have developed a new tool called CRC-PRO that allows physicians to quickly and accurately predict an individual's risk of colorectal cancer, as published in the current edition of the Journal of the American Board of Family Medicine. [More]
AACE releases first 2013 list of most frequently searched endocrine medical conditions

AACE releases first 2013 list of most frequently searched endocrine medical conditions

The American Association of Clinical Endocrinologists (AACE) today released its first annual list of the most frequently searched endocrine medical conditions for 2013, as measured by visits to the organization's patient education website, www.empoweryourhealth.org. [More]
Smoking, diets rich in animal products, alcohol have correlations with cancer incidence rates, says study

Smoking, diets rich in animal products, alcohol have correlations with cancer incidence rates, says study

A multicountry study just published in Nutrients finds that smoking, diets rich in animal products, and alcohol have the strongest correlations with cancer incidence rates. The cancer incidence rates are from 2008 as assembled by the International Agency for Research on Cancer of the World Health Organization. [More]
Psychiatrist offers tips for dealing with holiday stress and sadness problems of the season

Psychiatrist offers tips for dealing with holiday stress and sadness problems of the season

During the holidays, the goal should be to set the course somewhere "between Hallmark and heartache," a Vanderbilt psychiatrist says. In other words, don't strive for the perfect (you won't achieve it), and recognize and deal head-on with some of the stressors of the season. [More]

Endocrine Society issues scientific statement on health consequences of performance-enhancing drugs

A new Scientific Statement issued today by The Endocrine Society represents a comprehensive evaluation of available information on the prevalence and medical consequences of the use of performance-enhancing drugs. The statement highlights the clinical pharmacology, adverse effects and detection of many substances often classified as PEDs, identifies gaps in knowledge and aims to focus the attention of the medical community and policymakers on PED use as an important public health problem. [More]

Navidea seeks FDA approval for marketing Lymphoseek Injection for SLN detection

Navidea Biopharmaceuticals, Inc., a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, announced today that it has submitted a Supplemental New Drug Application with the U.S. Food and Drug Administration seeking approval for the marketing and sale of Lymphoseek (technetium 99m tilmanocept) Injection for sentinel lymph node detection in patients with head and neck cancer, an indication for which Lymphoseek was also granted Fast Track designation earlier this month. [More]