Tissue Engineering News and Research

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Dramatic advances in the fields of biochemistry, cell and molecular biology, genetics, biomedical engineering and materials science have given rise to the remarkable new cross-disciplinary field of tissue engineering. Tissue engineering uses synthetic or naturally derived, engineered biomaterials to replace damaged or defective tissues, such as bone, skin, and even organs.

Bone mineralization found to dampen metastatic progression of breast cancer

Tumor cells are known to be fickle sleeper agents, often lying dormant in distant tissues for years before reactivating and forming metastasis.

7 Aug 2023

Novel vaccine targets inflamed brain cells in Alzheimer's to modify the course of disease

A novel vaccine that targets inflamed brain cells associated with Alzheimer's disease may hold the key to potentially preventing or modifying the course of the disease, according to preliminary research presented at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions 2023.

31 Jul 2023

Lab-on-a-chip technologies offer new ways to assess stored red blood cells

Ziya Isiksacan, PhD, a research fellow in the Center for Engineering in Medicine and Surgery (CEMS) is the lead author, and Osman Berk Usta, PhD, an investigator in the CEMS at Massachusetts General Hospital and an associate professor of Surgery at Harvard Medical School, is the senior author of a new study published in PNAS, Assessment of Stored Red Blood Cells Through Lab-on-a-Chip Technologies for Precision Transfusion Medicine.

26 Jul 2023

AXT and CELLINK Form a Formidable Australian Bioprinting Partnership

3D bioprinting is experiencing rapid growth as the technology continues to evolve. This is certainly the case in Australia and AXT, who are already well entrenched in the field are pleased to announce that they are strengthening their position by partnering with CELLINK.

From AXT Pty Ltd 25 Jul 2023

Penn state researchers receive $2 million NIH grant to develop new bioprinting technology

Developing technology to quickly and efficiently bioprint human tissues at scale is the goal of a new project led by Penn State researchers.

21 Jul 2023

Penn State researchers receive $3 million grant to develop new revascularization techniques

The ability to regenerate and pattern blood vessels, the literal lifelines extending deep into soft tissues, remains an elusive milestone in regenerative medicine.

7 Jul 2023

Study unlocks the healing power of oral keratinocytes

Scientists have made significant progress in understanding the signals involved in regulating oral keratinocyte cell motility and proliferative capacity, offering new insights into potential pharmacological manipulation for regenerative medicine.

29 Jun 2023

Study shows therapeutic potential of HK for treating degenerative rotator cuff injury in humans

The incidence of degenerative rotator cuff injury in the elderly poses a significant economic burden. A novel study by investigators in The American Journal of Pathology, published by Elsevier, has established that mitochondrial sirtuin 3 (SIRT3) activator honokiol (HK) promotes healing of rotator cuff injury in aged mice.

20 Jun 2023

Bio-TUNE project aims to develop materials with high antibacterial potential and efficient tissue integration

The UPC's Biomaterials, Biomechanics and Tissue Engineering Group (BBT) leads the international project Bio-TUNE, which aims to develop multifunctional materials with high antibacterial potential and efficient tissue integration.

15 Jun 2023

Revolution in neuroscience: 2D nanomaterials propel advances in brain repair, treatment, and diagnosis

Review discusses the increasing importance of two-dimensional nanomaterials like graphene in neuroscience, highlighting their potential in nerve repair, creating brain-mimicking synaptic devices, and treating neurological disorders. It also considers the challenges and future prospects of these materials in this complex field.

11 Jun 2023

New platform to study how pathogens carried by mosquitoes impact and infect human cells and tissues

A UCF research team has engineered tissue with human cells that mosquitoes love to bite and feed upon -; with the goal of helping fight deadly diseases transmitted by the biting insects.

9 Jun 2023

New folate-targeting magnetic microrobot system shows great potential in cancer treatment

The limited ability of microrobots to assist drugs in entering cells hinders their therapeutic efficacy. To address this, the cancer-targeting molecule folic acid (FA) was introduced to microrobots to promote drug uptake by cancer cells via receptor-ligand-mediated endocytosis.

6 Jun 2023

Cancer researchers join together to fight lethal childhood brain cancer

Virginia Tech researchers with the Fralin Biomedical Research Institute at VTC have joined a Children's National Hospital effort to treat deadly brain tumors with ultrahigh frequency sound waves.

22 May 2023

Researchers evaluate the dual-therapeutic effect of gene therapy in mouse model of osteosarcoma

Investigators at Brigham and Women’s Hospital and collaborating institutions evaluated the dual-therapeutic effect of gene therapy in a clinically relevant model for common form of bone cancer.

8 May 2023

Research develops unique delivery system to treat osteosarcoma

New research has identified a potential therapeutic target and developed a unique delivery system to treat osteosarcoma, a bone cancer that primarily affects children and adolescents.

27 Apr 2023

Researchers shed light on the genetics behind facial changes in Down syndrome

Researchers at the Francis Crick Institute, King's College London and University College London have shed light on the genetics behind changes in the structure and shape of the face and head in a mouse model of Down Syndrome.

26 Apr 2023

New injectable cell therapy shows promise for treating osteoarthritis

Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have created a promising injectable cell therapy to treat osteoarthritis that both reduces inflammation and also regenerates articular cartilage.

21 Apr 2023

Light-activated SpyLigation can turn on proteins both inside and outside of living cells

Scientists can now use light to activate protein functions both inside and outside of living cells. The new method, called light-activated SpyLigation, can turn on proteins that are normally off to allow researchers to study and control them in more detail.

18 Apr 2023

AI-based design method synthesizes polymers that mimic blood plasma

Most life on Earth is based on polymers of 20 amino acids that have evolved into hundreds of thousands of different, highly specialized proteins. They catalyze reactions, form backbone and muscle and even generate movement.

20 Mar 2023

Upgraded tumor model points the way toward more effective cancer therapies

Tumor cells won't show their true selves in a petri dish, isolated from other cells.