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Scientists identify new potential target to combat acute myeloid leukemia

AML is not a single disease. It is a group of leukemias that develop in the bone marrow from progenitors of specialized blood cells, the so-called myeloid cells. Rapidly growing and dividing, these aberrant cells crowd the bone marrow and bloodstream, which can be fatal within weeks or months if the disease is left untreated.

18 May 2018

Study provides insights into how immune cells kill bacteria with acid

The first line of immune defense against invading pathogens like bacteria are macrophages, immune cells that engulf every foreign object that crosses their way. After enclosing it in intracellular membrane vesicles, a process called phagocytosis, macrophages kill their prey with acid.

17 May 2018

Opioid overdoses are rising faster among Latinos than whites or blacks. Why?

The tall, gangly man twists a cone of paper in his hands as stories from nearly 30 years of addiction pour out: the robbery that landed him in prison at age 17; never getting his high school equivalency diploma; going through the horrors of detox, maybe 40 times, including this latest bout, which he finished two weeks ago. He’s now in a residential treatment unit for at least 30 days.

17 May 2018

FutureNeuro and GreenLight Medicines team up to develop cannabis-based treatments for epilepsies

A new partnership between FutureNeuro, the SFI Research Centre for Chronic and Rare Neurological diseases based at RCSI and GreenLight Medicines, an indigenous Irish biopharmaceutical company has been formed to develop new cannabis-based treatments for drug-resistant epilepsies, and in particular, childhood epilepsies.

17 May 2018

Cleveland Clinic researcher wins NCI grant to delve into cancer genetics and radiation effectiveness

Can the genetic makeup of their cancers predict how patients with lung cancer will respond to radiation therapy? And can this information be used to advance a genetically guided strategy for patients with these tumors? Cleveland Clinic researcher and radiation oncologist Mohamed Abazeed, M.D., Ph.D., has been awarded a $2 million grant from the National Cancer Institute (NCI) to delve into those and other related questions.

15 May 2018

Gun safety programs do not reduce likelihood of children using firearms, study finds

Children who participate in gun safety programs often ignore what they learned when encountering a real firearm, according to a Rutgers School of Nursing study.

15 May 2018

Study uncovers promising new line of attack against aggressive prostate cancer

UC San Francisco researchers have discovered a promising new line of attack against lethal, treatment-resistant prostate cancer. Analysis of hundreds of human prostate tumors revealed that the most aggressive cancers depend on a built-in cellular stress response to put a brake on their own hot-wired physiology.

14 May 2018

Increasingly failing communication between cells' organelles is main cause of aging, shows study

A basic discovery of how the cellular functions are connected to control aging is presented in the journal Cell Metabolism.

11 May 2018

Researchers develop artificial intelligence method to help cancer patients worldwide

Before performing radiation therapy, radiation oncologists first carefully review medical images of a patient to identify the gross tumor volume -- the observable portion of the disease. They then design patient-specific clinical target volumes that include surrounding tissues, since these regions can hide cancerous cells and provide pathways for metastasis.

10 May 2018

Broadridge Financial Solutions acquires Ireland-based company, FundAssist

Broadridge Financial Solutions, Inc., a global fintech leader, has completed the acquisition of FundAssist Limited, a regulatory, marketing and sales solutions service provider to the global investments industry.

9 May 2018

Human papilloma virus vaccines can protect against cervical lesions in young women

New evidence published today in the Cochrane Library shows that human papilloma virus vaccines protect against cervical lesions in young women, particularly in those who are vaccinated between the ages of 15 and 26.

9 May 2018

Findings confirm analytical principle that describes mutational processes and cancer development

When a cell develops into a tumor, something has gone terribly wrong: the uncontrolled growth, invasion of nearby tissues and finally metastasis are the result of many consecutive DNA mutations.

9 May 2018

Scientists discover how potential new drug targets spinal muscular atrophy

Spinal muscular atrophy (SMA) is a genetic disease that can leave infants with weak muscles and trouble breathing. Many with the disease die before age two. To help these patients, doctors need therapies that target the genetic mutation and stop its progression.

8 May 2018

Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

A new study in Biological Psychiatry reports that dementia-related and psychiatric-related proteins cluster together to form aggregates in the brain, leading to abnormal cell function and behavior.

8 May 2018

Alnylam achieves delivery of novel siRNAs conjugates to the central nervous system

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that the Company has achieved delivery of novel small interfering RNA conjugates to the central nervous system and is planning to advance a pipeline of investigational RNAi therapeutics into clinical development.

8 May 2018

Nuclear pore complexes are critical for survival of circulating T cells, study shows

Nuclear pore complexes in the nuclear membrane not only control the transport of molecules into and out of the nucleus- they play an essential role in the survival of T cells.

8 May 2018

Tufts CTSI receives 2018 Clinical and Translational Science Award

Tufts University and Tufts Medical Center today announced that the National Institutes of Health's National Center for Advancing Translational Sciences has named Tufts Clinical and Translational Science Institute a recipient of the 2018 Clinical and Translational Science Awards.

7 May 2018

Researchers develop highly elastic biodegradable hydrogel for cell printing

Researchers at The University of Texas at Arlington have developed a highly elastic biodegradable hydrogel for bio-printing of materials that mimic natural human soft tissues.

4 May 2018

Study provides vital information to develop successful PI5P4K inhibitors for p53-mutant cancers

One major hallmark of cancer cells is their ability to adapt to stressful conditions such as nutrient deprivation. Rapidly growing tumor cells must compete for the ever-diminishing supply of nutrients in the surrounding environment to survive and proliferate. Targeting these adaptive mechanisms represents a promising approach for cancer therapeutics.

3 May 2018

New research hub set to transform Australia’s medical technology sector

A new research hub is set to transform Australia’s medical technology sector by developing cost-competitive technologies for the rapid production of medical devices.

2 May 2018

Translation News and Research

Scientists identify new potential target to combat acute myeloid leukemia

Study provides insights into how immune cells kill bacteria with acid

Opioid overdoses are rising faster among Latinos than whites or blacks. Why?

FutureNeuro and GreenLight Medicines team up to develop cannabis-based treatments for epilepsies

Cleveland Clinic researcher wins NCI grant to delve into cancer genetics and radiation effectiveness

Gun safety programs do not reduce likelihood of children using firearms, study finds

Study uncovers promising new line of attack against aggressive prostate cancer

Increasingly failing communication between cells' organelles is main cause of aging, shows study

Researchers develop artificial intelligence method to help cancer patients worldwide

Broadridge Financial Solutions acquires Ireland-based company, FundAssist

Human papilloma virus vaccines can protect against cervical lesions in young women

Findings confirm analytical principle that describes mutational processes and cancer development

Scientists discover how potential new drug targets spinal muscular atrophy

Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

Alnylam achieves delivery of novel siRNAs conjugates to the central nervous system

Nuclear pore complexes are critical for survival of circulating T cells, study shows

Tufts CTSI receives 2018 Clinical and Translational Science Award

Researchers develop highly elastic biodegradable hydrogel for cell printing

Study provides vital information to develop successful PI5P4K inhibitors for p53-mutant cancers

New research hub set to transform Australia’s medical technology sector

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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