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UNMC seeking patients with lymphoma to evaluate two-drug oral therapy

UNMC seeking patients with lymphoma to evaluate two-drug oral therapy

The University of Nebraska Medical Center is seeking 24 patients to enroll in a Phase 2a study to evaluate the safety and efficacy of two oral cancer drugs for patients with diffuse large B-cell lymphoma who have relapsed or are resistant to other traditional therapies. [More]
NIH scientists create Salmonella-infected mouse model to study life-threatening meningitis

NIH scientists create Salmonella-infected mouse model to study life-threatening meningitis

National Institutes of Healthscientists have established in mice a way to study potentially life-threatening meningitis caused by Salmonella. [More]
Researchers track severely brain injured woman to reveal biological process of recovery

Researchers track severely brain injured woman to reveal biological process of recovery

A severely brain injured woman, who recovered the ability to communicate using her left eye, restored connections and function of the areas of her brain responsible for producing expressive language and responding to human speech, according to new research from Weill Cornell Medicine scientists. [More]
Study identifies recurrent genomic alterations in subset of breast cancer

Study identifies recurrent genomic alterations in subset of breast cancer

A genomic analysis study by Rutgers Cancer Institute of New Jersey investigators and other colleagues has identified recurrent genomic alterations in a subset of breast cancer that are typically associated with a form of thyroid cancer and an intestinal birth defect known as Hirschsprung disease. [More]
Albert Einstein College of Medicine awarded NIH grant to launch diabetes translation research center

Albert Einstein College of Medicine awarded NIH grant to launch diabetes translation research center

The National Institutes of Health has awarded researchers at Albert Einstein College of Medicine and Montefiore Health System a five-year, $2.9-million grant to launch a new center, one of only 8 in the country, for diabetes translation research. [More]
Personalized cancer vaccine improves outcomes for patients with AML, clinical study shows

Personalized cancer vaccine improves outcomes for patients with AML, clinical study shows

A personalized cancer vaccine markedly improved outcomes for patients suffering from acute myeloid leukemia (AML), a potentially lethal blood cancer, in a clinical trial led by investigators at Beth Israel Deaconess Medical Center. [More]
Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following publication of research findings today in the journal Science Translational Medicine. [More]
Brain activity of healthy older adults could help predict risk of falling

Brain activity of healthy older adults could help predict risk of falling

Falls are the leading cause of fatal and non-fatal injuries among older Americans and all too often lead to physical decline and loss of independence. [More]
Scientists find novel way for earlier detection of deadly Merkel cell carcinoma

Scientists find novel way for earlier detection of deadly Merkel cell carcinoma

Scientists have found a way to detect earlier if a deadly cancer, Merkel cell carcinoma (MCC), is recurring in patients, according to a paper to be published 11 a.m. Eastern time, Dec. 7, in the journal Cancer. [More]
Detecting inflammation in diabetic patients

Detecting inflammation in diabetic patients

As well as presenting with high blood glucose, diabetic patients have chronic low-grade inflammation, which can be measured by a range of inflammatory markers such as so-called high-sensitive CRP, TNFa and IL-6 as well as a full blood cell count. [More]
Leukaemia patients could safely reduce side effects of drug by cutting dose in half, study shows

Leukaemia patients could safely reduce side effects of drug by cutting dose in half, study shows

Patients with a chronic type of leukaemia could safely reduce the side effects of life-long treatment by cutting their dose in half, according to the results of a University of Liverpool led study presented at an international conference in America this week. [More]
NIH scientists unravel chain of events that lead to fatal outcomes in cerebral malaria

NIH scientists unravel chain of events that lead to fatal outcomes in cerebral malaria

Using state-of-the-art brain imaging technology, scientists at the National Institutes of Health filmed what happens in the brains of mice that developed cerebral malaria (CM). [More]
Researchers develop new microfluidic device to study brain inflammation

Researchers develop new microfluidic device to study brain inflammation

The blood-brain barrier is a network of specialized cells that surrounds the arteries and veins within the brain. It forms a unique gateway that both provides brain cells with the nutrients they require and protects them from potentially harmful compounds. [More]
Researchers find strong link between angiotensin receptor autoantibodies and increased risk of frailty

Researchers find strong link between angiotensin receptor autoantibodies and increased risk of frailty

Results of a new study led by Johns Hopkins researchers offer new evidence for a strong link between angiotensin receptor autoantibodies and increased risk of frailty. [More]
Experts discuss ways to integrate whole genome analysis into clinical practice at Congenica webinar

Experts discuss ways to integrate whole genome analysis into clinical practice at Congenica webinar

Whole genome analysis – where all of a patient’s genes are screened for potential disease causing variants – offers the potential for a rapid, responsive NHS testing service. [More]
CBD oil may reduce frequency and severity of seizures in patients with epilepsy, UAB study shows

CBD oil may reduce frequency and severity of seizures in patients with epilepsy, UAB study shows

Cannabidiol oil, also known as CBD oil, reduces the frequency and severity of seizures in children and adults with severe, intractable epilepsy, according to findings presented by researchers from the University of Alabama at Birmingham at the American Epilepsy Society 70th Annual Meeting. [More]
Researchers develop portable sensor for fast, accurate assessment of blood's clotting ability

Researchers develop portable sensor for fast, accurate assessment of blood's clotting ability

Case Western Reserve University researchers have developed a portable sensor that can assess the clotting ability of a person's blood 95 times faster than current methods—using only a single drop of blood. [More]
Combination of demineralized bone and gene therapy shows promise for treating pseudarthrosis

Combination of demineralized bone and gene therapy shows promise for treating pseudarthrosis

A team headed by Professor Albert Rizvanov, director of the Gene and Cell Technologies Open Lab, created a gene therapy drug that encodes growth factors for the stimulation of blood vessel and bone formation. [More]
Delay in giving adrenaline shots after cardiac arrest lowers survival rates of patients

Delay in giving adrenaline shots after cardiac arrest lowers survival rates of patients

Hospitals in which the administration of epinephrine to patients whose hearts have stopped is delayed beyond five minutes have significantly lower survival rates of those patients, a new study led by a cardiologist at UT Southwestern Medical Center finds. [More]
New study finds genetic link between Parkinson's disease and cognitive decline

New study finds genetic link between Parkinson's disease and cognitive decline

Although the hallmark symptoms of Parkinson's disease (PD) - such as involuntary shaking, slowness of movement and muscle rigidity - are related to movement, recent evidence has suggested that memory impairment plays an outsized role in diminished quality of life and the burden placed on caregivers. [More]
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