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Cedars-Sinai investigators developing novel treatment for locally advanced pancreatic cancer

Cedars-Sinai investigators developing novel treatment for locally advanced pancreatic cancer

Investigators at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute are developing a novel, multistep investigational treatment for one of the most complex and difficult-to-treat forms of the disease, locally advanced pancreatic cancer. [More]
Understanding how some cells in the brain and nervous system turn cancerous

Understanding how some cells in the brain and nervous system turn cancerous

Scientists from the Sloan-Kettering Institute for Cancer Research in New York with the help of Plymouth University Peninsula Schools of Medicine and Dentistry have completed research which for the first time brings us nearer to understanding how some cells in the brain and nervous system become cancerous. [More]
SIV can be entrenched in tissues before virus is detectable in blood plasma

SIV can be entrenched in tissues before virus is detectable in blood plasma

Scientists have generally believed that HIV and its monkey equivalent, SIV, gain a permanent foothold in the body very early after infection, making it difficult to completely eliminate the virus even after antiretroviral therapy has controlled it. [More]
Study finds microglia increase neuronal firing and enhance brain cell survival after injury

Study finds microglia increase neuronal firing and enhance brain cell survival after injury

A type of immune cell widely believed to exacerbate chronic adult brain diseases, such as Alzheimer's disease and multiple sclerosis (MS), can actually protect the brain from traumatic brain injury (TBI) and may slow the progression of neurodegenerative diseases, according to Cleveland Clinic research published today in the online journal Nature Communications. [More]
Scientists develop next-generation platelet bioreactor to generate functional human platelets

Scientists develop next-generation platelet bioreactor to generate functional human platelets

Scientists at Brigham and Women's Hospital (BWH) have developed a scalable, next-generation platelet bioreactor to generate fully functional human platelets in vitro. The work is a major biomedical advancement that will help address blood transfusion needs worldwide. [More]
Peer-led interventions can reduce depression and anxiety in mothers of kids with autism

Peer-led interventions can reduce depression and anxiety in mothers of kids with autism

Peer-led interventions that target parental well-being can significantly reduce stress, depression and anxiety in mothers of children with disabilities, according to new findings released today in the journal Pediatrics. [More]
Researchers propose ‘microbiome cloud model’ to understand variation in individual's microbiome composition

Researchers propose ‘microbiome cloud model’ to understand variation in individual's microbiome composition

The Human Microbiome Project (HMP) is a global initiative to identify and characterize the microorganisms present at multiple sites in the human body. [More]
Experts join MD Anderson to end cancer

Experts join MD Anderson to end cancer

The University of Texas MD Anderson Cancer Center is pleased to announce that one of the world's preeminent experts in breast cancer research and treatment, V. Craig Jordan, Ph.D., will join the institution's efforts to end cancer. Jordan is considered the "Father of Tamoxifen," the groundbreaking therapeutic drug that has saved countless lives. [More]
Findings point to biological mechanisms and pathways that may underlie schizophrenia

Findings point to biological mechanisms and pathways that may underlie schizophrenia

As part of a multinational, collaborative effort, researchers from the University of North Carolina School of Medicine and scores of other institutions from all over the world have helped identify over 100 locations in the human genome associated with the risk of developing schizophrenia, in what is the largest genomic study published on any psychiatric disorder to date. [More]
Study provides evidence for intranasal nerve growth factor for repair of spinal cord injury

Study provides evidence for intranasal nerve growth factor for repair of spinal cord injury

Nerve growth factor can be delivered to the brain by intranasal administration without risk for treatment of brain diseases. [More]
Marmoset's unique rapid reproductive system sheds new light on evolution and primate biology

Marmoset's unique rapid reproductive system sheds new light on evolution and primate biology

A team of scientists from around the world led by Baylor College of Medicine and Washington University in St. Louis has completed the genome sequence of the common marmoset - the first sequence of a New World Monkey - providing new information about the marmoset's unique rapid reproductive system, physiology and growth, shedding new light on primate biology and evolution. [More]
Common genetic variation in gene may modify cardiovascular benefit of aspirin

Common genetic variation in gene may modify cardiovascular benefit of aspirin

Aspirin is the gold standard for antiplatelet therapy and a daily low-dose aspirin is widely prescribed for the prevention of cardiovascular disease. [More]
Three leading universities join forces to find better solutions for patients with craniofacial defects

Three leading universities join forces to find better solutions for patients with craniofacial defects

One in every 2,000 babies is born with a skull that can't grow normally. Various sections of these babies' skulls are fused together at joints called sutures, constricting the developing brain and disrupting vision, sleep, eating and IQ. For these young patients, risky skull-expanding surgeries become an almost annual event. [More]
Scientists identify genes that may help predict steroid responsiveness in people with EoE

Scientists identify genes that may help predict steroid responsiveness in people with EoE

Results from a clinical trial show that high doses of the corticosteroid fluticasone propionate safely and effectively induce remission in many people with eosinophilic esophagitis (EoE), a chronic inflammatory disease of the esophagus characterized by high levels of white blood cells called eosinophils. [More]
National Drug Early Warning System to monitor emerging drug trends

National Drug Early Warning System to monitor emerging drug trends

An innovative National Drug Early Warning System (NDEWS) is being developed to monitor emerging trends that will help health experts respond quickly to potential outbreaks of illicit drugs such as heroin and to identify increased use of designer synthetic compounds. [More]
UH Case Medical Center signs agreement with ARUP to offer DEEPGEN-HIV test

UH Case Medical Center signs agreement with ARUP to offer DEEPGEN-HIV test

University Hospitals (UH) Case Medical Center has signed an agreement with ARUP Laboratories, a major national clinical reference laboratory that offers an extensive menu of highly complex and unique medical tests to hospitals, medical schools, and other nonprofit and commercial organizations throughout the United States. [More]

New article describes about crowdsourcing and drug repurposing needs

Experimental drugs proven safe but perhaps not sufficiently effective in initial testing or against a first disease target may sit gathering dust on the shelves of pharmaceutical companies. [More]
Deadly neurodegenerative disease treated in worms gives hope for humans

Deadly neurodegenerative disease treated in worms gives hope for humans

An untreatable and deadly neurodegenerative disease has been modelled and treated in worms by University of Liverpool researchers, suggesting a cure could be found for humans. [More]
Phase III research shows that new drug improves symptoms related to plaque psoriasis

Phase III research shows that new drug improves symptoms related to plaque psoriasis

Randomized, phase III research from the University of Alabama at Birmingham shows that a new drug improves symptoms related to moderate to severe plaque psoriasis, a chronic skin disease of scaling and inflammation. [More]
Investigators identify gene that underlies devastating autoinflammatory condition in children

Investigators identify gene that underlies devastating autoinflammatory condition in children

Investigators have identified a gene that underlies a very rare but devastating autoinflammatory condition in children. Several existing drugs have shown therapeutic potential in laboratory studies, and one is currently being studied in children with the disease, which the researchers named STING-associated vasculopathy with onset in infancy (SAVI). [More]