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Scientists reveal how disruption of DISC1 gene involved in mental illness affects the brain

Scientists reveal how disruption of DISC1 gene involved in mental illness affects the brain

Scientists have for the first time shown how the disruption of a key gene involved in mental illness impacts on the brain. [More]
TGen professor to receive top award from Arizona Medical Association

TGen professor to receive top award from Arizona Medical Association

Dr. Daniel D. Von Hoff, Distinguished Professor and Physician-In-Chief of the Translational Genomics Research Institute, will receive one of the top awards May 29 from the Arizona Medical Association. [More]
Mayo Clinic scientists create mouse model of ALS, FTD caused by mutations in C9ORF72 gene

Mayo Clinic scientists create mouse model of ALS, FTD caused by mutations in C9ORF72 gene

Scientists at Mayo Clinic, Jacksonville, Florida created a novel mouse that exhibits the symptoms and neurodegeneration associated with the most common genetic forms of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), both of which are caused by a mutation in the a gene called C9ORF72. [More]
Treatment outcomes in type 1 diabetes could be improved across all age groups

Treatment outcomes in type 1 diabetes could be improved across all age groups

In a sweeping analysis assessing the current state of diabetes treatment in the U.S., T1D Exchange researchers conclude that there remains considerable room for improving treatment outcomes in type 1 diabetes across all age groups, but especially for adolescents and young adults. [More]
Clinical genomic sequencing could impact treatment decisions in advanced prostate cancer patients

Clinical genomic sequencing could impact treatment decisions in advanced prostate cancer patients

An international collaboration of researchers are advancing precision medicine to men with advanced prostate cancer. [More]
TGen and Baylor partnership set to increase treatment options for cancer patients

TGen and Baylor partnership set to increase treatment options for cancer patients

The Translational Genomics Research Institute (TGen) and Baylor Research Institute (BRI) at Dallas today announce an agreement that will focus on accelerating early detection and treatments for patients with a broad range of cancers. [More]
Johns Hopkins scientists safely use immune cells to treat multiple myeloma

Johns Hopkins scientists safely use immune cells to treat multiple myeloma

In a report on what is believed to be the first small clinical trial of its kind, researchers at the Johns Hopkins Kimmel Cancer Center say they have safely used immune cells grown from patients' own bone marrow to treat multiple myeloma, a cancer of white blood cells. [More]
Second-generation antibiotic shows promise against common bacterial infections

Second-generation antibiotic shows promise against common bacterial infections

Researchers led by St. Jude Children's Research Hospital scientists have developed a second-generation antibiotic that shows early effectiveness against common bacterial infections that pose a serious health threat to children and adults. [More]
RepliCel's autologous cell treatment for Achilles tendinosis to be presented at ISCT 2015

RepliCel's autologous cell treatment for Achilles tendinosis to be presented at ISCT 2015

RepliCel Life Sciences Inc., a clinical stage regenerative medicine company focused on the development of autologous cell therapies, announced today an upcoming poster presentation at the International Society for Cellular Therapy on RepliCel's autologous cell treatment for chronic Achilles tendinosis currently in a Phase 1/2 clinical trial. [More]
Novel drug target identified for treating rheumatoid arthritis

Novel drug target identified for treating rheumatoid arthritis

Researchers at the La Jolla Institute for Allergy and Immunology, in collaboration with colleagues the University of California, San Diego, identified a novel drug target for the treatment of rheumatoid arthritis that focuses on the cells that are directly responsible for the cartilage damage in affected joints. [More]
AACC receives three 2015 Hermes Creative Awards

AACC receives three 2015 Hermes Creative Awards

AACC, a global scientific and medical professional organization dedicated to better health through laboratory medicine, is pleased to announce that it has received three 2015 Hermes Creative Awards. These awards recognize the association for the exceptional writing and design of its news publications and website, which help laboratory medicine professionals worldwide stay informed about important issues in the field and find solutions to challenging patient health problems. [More]
New UCLA study finds Naltrexone drug as promising treatment for methamphetamine addiction

New UCLA study finds Naltrexone drug as promising treatment for methamphetamine addiction

A new study by UCLA researchers has found that Naltrexone, a drug used to treat alcoholism, may also be a promising treatment for addiction to methamphetamine. [More]
vTv Therapeutics enrolls first patients in azeliragon Phase 3 trial for treatment of mild Alzheimer's disease

vTv Therapeutics enrolls first patients in azeliragon Phase 3 trial for treatment of mild Alzheimer's disease

vTv Therapeutics LLC today announced enrollment of the first patients into STEADFAST (Single Trial Evaluating Alzheimer's Disease Following Addition to Symptomatic Therapy), vTv's Phase 3 placebo controlled trial of azeliragon, an oral antagonist of the Receptor for Advanced Glycation Endproducts (RAGE) for treatment of mild Alzheimer's disease. [More]
New microfluidic chip can capture rare clusters of circulating tumor cells

New microfluidic chip can capture rare clusters of circulating tumor cells

Researchers have developed a microfluidic chip that can capture rare clusters of circulating tumor cells, which could yield important new insights into how cancer spreads. The work was funded by the National Institute of Biomedical Imaging and Bioengineering, part of the National Institutes of Health. [More]
Study finds new colon cancer screening as promising alternative to colonoscopy for African Americans

Study finds new colon cancer screening as promising alternative to colonoscopy for African Americans

In a first-of-its-kind clinical trial, physician-scientists at University Hospitals Case Medical Center Seidman Cancer Center and Case Western Reserve University School of Medicine found that a new non-invasive technology for colon cancer screening is a promising alternative to colonoscopy for African Americans. [More]
Two-drug combination improves lung function in some cystic fibrosis patients

Two-drug combination improves lung function in some cystic fibrosis patients

The combination of two drugs — an investigational drug used in conjunction with an already FDA-approved medication — improved lung function in patients with one form of cystic fibrosis, according to two new studies. [More]
Researchers uncover major link between human body clock and immune system

Researchers uncover major link between human body clock and immune system

An important link between the human body clock and the immune system has relevance for better understanding inflammatory and infectious diseases, discovered collaborators at the Perelman School of Medicine at the University of Pennsylvania and Trinity College, Dublin. [More]
Fibromyalgia now considered as a lifelong central nervous system disorder

Fibromyalgia now considered as a lifelong central nervous system disorder

Fibromyalgia is the second most common rheumatic disorder behind osteoarthritis and, though still widely misunderstood, is now considered to be a lifelong central nervous system disorder, which is responsible for amplified pain that shoots through the body in those who suffer from it. [More]
Combined therapy shows promise in cystic fibrosis patients

Combined therapy shows promise in cystic fibrosis patients

Treatment with two medications that target the most common genetic cause of cystic fibrosis improves lung function and lowers the rate of pulmonary exacerbations, according to the results from a Phase III international clinical trial published online in the New England Journal of Medicine on May 17, 2015. [More]
APS honors recipients of Clinical Centers of Excellence in Pain Management Awards

APS honors recipients of Clinical Centers of Excellence in Pain Management Awards

The American Pain Society today honored the recipients of its annual Clinical Centers of Excellence in Pain Management Awards recognizing the nation's outstanding pain care centers. Five multidisciplinary pain programs were recognized. [More]
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