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Perelman School of Medicine opens new medical education center

Perelman School of Medicine opens new medical education center

With the opening of the Henry A. Jordan M'62 Medical Education Center, the Perelman School of Medicine at the University of Pennsylvania has expanded its urban campus with an innovative new facility that's redefining medical education for 21st century doctors. [More]
Altered dopamine signaling may contribute to autism

Altered dopamine signaling may contribute to autism

Newly discovered genetic variations linked to autism spectrum disorder (ASD) disrupt the function of the dopamine transporter, suggesting that altered dopamine signaling contributes to this common developmental condition, according to a Vanderbilt University-led research team. [More]
Study recommends normalizing blood pressure in pregnant women

Study recommends normalizing blood pressure in pregnant women

Throughout her career in Canada and the UK, Dr. Laura Magee has taken a restrained approach to use of blood pressure-lowering medication in her pregnant patients, fearing that lowering pressure could reduce the flow of blood and vital nutrients to their babies. [More]
Damon Runyon Cancer Research Foundation names 15 new Damon Runyon Fellows

Damon Runyon Cancer Research Foundation names 15 new Damon Runyon Fellows

The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting innovative early career researchers, named 15 new Damon Runyon Fellows at its fall Fellowship Award Committee review. The recipients of this prestigious, four-year award are outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators across the country. [More]
NCCN commemorates 20 years of advancing high-quality, high-value cancer care

NCCN commemorates 20 years of advancing high-quality, high-value cancer care

On January 31, 2015, the National Comprehensive Cancer Network celebrates its 20th anniversary. Originally announced as an alliance of 13 leading cancer centers in 1995, NCCN has grown to a network of 25 academic cancer centers; the NCCN mission as an alliance of leading academic cancer centers devoted to patient care, research, and education, is to improve the quality, effectiveness, and efficiency of cancer care so that patients can live better lives. [More]
Cell-penetrating nanoparticles can efficiently transport oligonucleotide drugs into cells

Cell-penetrating nanoparticles can efficiently transport oligonucleotide drugs into cells

Therapeutic oligonucleotide analogs represent a new and promising family of drugs that act on nucleic acid targets such as RNA or DNA; however, their effectiveness has been limited due to difficulty crossing the cell membrane. [More]
Pancreatic cancer cells know a way to sidestep chemotherapy, reveal Fox Chase researchers

Pancreatic cancer cells know a way to sidestep chemotherapy, reveal Fox Chase researchers

Pancreatic cancer is one of the deadliest forms of the disease. The American Cancer Society's most recent estimates for 2014 show that over 46,000 people will be diagnosed with pancreatic cancer and more than 39,000 will die from it. Now, research led by Timothy J. Yen, PhD, Professor at Fox Chase Cancer Center, reveals that one reason this deadly form of cancer can be so challenging to treat is because its cells have found a way to sidestep chemotherapy. [More]
UCSD, UCSF launch new project to map cancer cells

UCSD, UCSF launch new project to map cancer cells

Researchers from the University of California, San Diego School of Medicine and University of California, San Francisco, with support from a diverse team of collaborators, have launched an ambitious new project - dubbed the Cancer Cell Map Initiative or CCMI - to determine how all of the components of a cancer cell interact. [More]
UAB doctor says measles can be halted with safe, effective measles vaccine

UAB doctor says measles can be halted with safe, effective measles vaccine

An ongoing, multistate measles outbreak linked to a California amusement park has already caused 68 confirmed cases between Jan. 1 and 23, according to the Centers for Disease Control and Prevention. [More]
People who carry longevity gene variant have larger brain region

People who carry longevity gene variant have larger brain region

People who carry a variant of a gene that is associated with longevity also have larger volumes in a front part of the brain involved in planning and decision-making, according to researchers at UC San Francisco. [More]
Researchers advance generalized concept for future studies of mental resilience

Researchers advance generalized concept for future studies of mental resilience

Researchers at the Research Center Translational Neurosciences of Johannes Gutenberg University Mainz in Germany have advanced a generalized concept as the basis for future studies of mental resilience. Their new approach is based on a mechanistic theory which takes as its starting point the appraisals made by the brain in response to exposure to stressful or threatening situations. [More]
Alzheimer's Association announces new research grants to study potential drug therapies

Alzheimer's Association announces new research grants to study potential drug therapies

Many academic researchers and pharmaceutical companies have identified new Alzheimer's drug therapy candidates, but lack the funding to move them into human testing. At the same time, few funding sources support early-phase clinical drug trials. As a result, too many promising studies stall out early in the discovery process. [More]
Researchers probe possibility of reversing medications' adverse cognitive effects

Researchers probe possibility of reversing medications' adverse cognitive effects

Whether the adverse cognitive effects of medications can be reversed is of significant importance to an aging population, their caregivers and their families, as well as to an overburdened health care system. [More]
Improving prefrontal cortex activity could help autistic people regulate emotions

Improving prefrontal cortex activity could help autistic people regulate emotions

Tantrums, irritability, self-injury, depression, anxiety. These symptoms are associated with autism, but they're not considered core symptoms of the disorder. Researchers from the UNC School of Medicine are challenging this assertion. They have used functional MRI to show that - when it comes to the ability to regulate emotions - brain activity in autistic people is significantly different than brain activity in people without autism. [More]
Developmental salivary biomarkers linked to feeding success in newborns

Developmental salivary biomarkers linked to feeding success in newborns

Results from a study published online in the Journal of Pediatrics hold the potential to substantially improve clinical decision-making to determine when a premature newborn is ready for oral feeding. The study describes developmental salivary biomarkers associated with feeding success in newborns, markers that could lead to development of objective assessment tools for caregivers. [More]
Researchers devise novel way to generate corneal stem cells for treating corneal blindness

Researchers devise novel way to generate corneal stem cells for treating corneal blindness

Researchers in the Cedars-Sinai Board of Governors Regenerative Medicine Institute have devised a novel way to generate transplantable corneal stem cells that may eventually benefit patients suffering from life-altering forms of blindness. [More]
CHLA researchers develop new protein-based therapy against drug-resistant leukemia cells

CHLA researchers develop new protein-based therapy against drug-resistant leukemia cells

Resistance of leukemia cells to contemporary chemotherapy is one of the most formidable obstacles to treating acute lymphoblastic leukemia (ALL), the most common form of childhood cancer. Now researchers at Children's Hospital Los Angeles have designed and developed a new protein-based therapy they believe will prove highly effective against drug-resistant leukemia cells. [More]
Imperial College professor honored with Helmholtz International Fellow Award

Imperial College professor honored with Helmholtz International Fellow Award

The British cell biologist Professor Amanda Gay Fisher of Imperial College London has been honored with the Helmholtz International Fellow Award for her excellent research. Fisher is one of seven outstanding researchers from abroad who received the award, each of which is endowed with 20,000 euros. According to the Helmholtz Association, Germany's largest scientific organization, the award also includes an invitation to visit one or several Helmholtz research centers. [More]
New imaging technique increases detection rates of invasive breast cancers

New imaging technique increases detection rates of invasive breast cancers

A new breast imaging technique pioneered at Mayo Clinic nearly quadruples detection rates of invasive breast cancers in women with dense breast tissue, according to the results of a major study published this week in the American Journal of Roentgenology. [More]
Study examines effects of beetroot juice on physical function of COPD patients

Study examines effects of beetroot juice on physical function of COPD patients

A Wake Forest University study to investigate the effects of acute beetroot juice ingestion on the exercise capacity of COPD patients shows some promise, but a larger clinical trial is needed to verify results. [More]